The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.
Impact of multidrug-resistant Pseudomonas aeruginosa infection on patient outcomes
Open accessAbstract
Rates of antibiotic resistance in Pseudomonas aeruginosa are increasing worldwide. The multidrug-resistant (MDR) phenotype in P. aeruginosa could be mediated by several mechanisms including multidrug efflux systems, enzyme production, outer membrane protein (porin) loss and target mutations. Currently, no international consensus on the definition of multidrug resistance exists, making direct comparison of the literature difficult. Inappropriate empirical therapy has been associated with increased mortality in P. aeruginosa infections; delays in starting appropriate therapy may contribute to increased length of hospital stay and persistence of infection. In addition, worse clinical outcomes may be associated with MDR infections owing to limited effective antimicrobial options. This article aims to summarize the contemporary literature on patient outcomes following infections caused by drug-resistant P. aeruginosa. The impact of antimicrobial therapy on patient outcomes, mortality and morbidity; and the economic impact of MDR P. aeruginosa infections will be examined.
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Cited by
Ackermann, M., Kempf, H., Hetzel, M., Hesse, C., Hashtchin, A. R., Brinkert, K., Schott, J. W., Haake, K., Kühnel, M. P., Glage, S., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-07570-7 · Cited by 165
Thabit, A. K., Crandon, J. L., & Nicolau, D. P. (2015) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2015.993381 · Cited by 160
Healthcare-associated viral and bacterial infections in dentistry
Laheij, A. M. G. A., Kistler, J. O., Belibasakis, G. N., Välimaa, H., de Soet, J. J., & 2011, E. O. M. W. (. (2012) · Journal of Oral Microbiology · doi:10.3402/jom.v4i0.17659 · Cited by 116
Tagliaferri, T. L., Vieira, C. D., de Carvalho, M. A. R., Ladeira, L. C. D., Magalhães, P. P., de Macêdo Farias, L., & dos Santos, S. G. (2017) · Letters in Applied Microbiology · doi:10.1111/lam.12775 · Cited by 3
Metadata
- Authors
- Hirsch, E. B., & Tam, V. H.
- Venue
- Expert Review of Pharmacoeconomics & Outcomes Research
- Publisher
- Informa UK Limited
- Published
- 2010-08
- Volume
- 10
- Issue
- 4
- Pages
- 441-451
- ISSN
- 1473-7167 (ISSN-L)
- 1744-8379
- OpenAlex
- W2033235589
- Cited by
- 406
- References
- 63
- FWCI
- 4.16
- Type
- journal article
- Language
- en
- Open access
- green
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- Hirsch, E. B., & Tam, V. H. (2010). Impact of multidrug-resistant Pseudomonas aeruginosa infection on patient outcomes. Expert Review of Pharmacoeconomics & Outcomes Research. https://doi.org/10.1586/erp.10.49
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
