Cited by 107Nanotechnology research and applicationsAdvancements in Transdermal Drug DeliveryPharmacology and Nanomedicine Research

Nanotechnology in Dermatology

Open access
Antonio, Joao Roberto, Antonio, Carlos Roberto, Cardeal, Izabela Lidia Soares, Ballavenuto, Julia Maria Avelino, Oliveira, Joao Rodrigo·2014·Anais Brasileiros de Dermatologia

Abstract

The scientific community and general public have been exposed to a series of achievements attributed to a new area of knowledge: Nanotechnology. Both abroad and in Brazil, funding agencies have launched programs aimed at encouraging this type of research. Indeed, for many who come into contact with this subject it will be clear the key role that chemical knowledge will play in the evolution of this subject. And even more, will see that it is a science in which the basic structure is formed by distilling different areas of inter-and multidisciplinary knowledge along the lines of new paradigms. In this article, we attempt to clarify the foundations of nanotechnology, and demonstrate their contribution to new advances in dermatology as well as medicine in general. Nanotechnology is clearly the future.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1590/abd1806-4841.20142228

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Nano-emulsion encapsulation of active ingredients has drawn attention to nanotechnology drug delivery systems for the treatment of hair disorders such as alopecia areata and rogenetica.

    “The use of nano-emulsion to encapsulate active ingredients has drawn attention to nanotechnology drug delivery systems for the treatment of hair disorders such as alopecia areata and rogenetica.”

    From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [85]

    The “Treatment of scalp diseases” section (page unavailable) discusses encapsulated ingredients in nanoparticle delivery systems for androgenic alopecia and alopecia areata. It does not identify nano-emulsions as the delivery system for those treatments; the examples given include nanoparticles and liposomes. (LLM, conf=0.86)

    Experimental — accuracy not yet measured
  • The use of silver and metal oxide nanoparticles with antifungal activity in nail polish for both therapeutic and cosmetic purposes in the treatment of onychomycosis is a novel approach.

    “For example, the use of silver and metal oxide nanoparticles with antifungal activity in nail polish for both therapeutic and cosmetic purposes in the treatment of onychomycosis is a novel approach.”

    From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [85]

    The NANOPARTICLES section describes silver and metal-oxide nanoparticles, and the Treatment of inflammatory disorders section mentions nanoparticle formulations of antifungal drugs. Neither section describes antifungal silver or metal-oxide nanoparticles in nail polish, or their therapeutic and cosmetic use for onychomycosis; the Antisepsis and asepsis section discusses their antibacterial properties instead. Page numbers were not available in our copy. (LLM, conf=0.78)

    Experimental — accuracy not yet measured
  • These nano-emulsion systems carry active ingredients deeper into the hair follicle openings and may serve as a depot for prolonged drug release within the hair follicle.

    “These systems carry active ingredients deeper into the hair follicle openings and may serve as a depot for prolonged drug release within the hair follicle.”

    From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [85]

    The “Treatment of scalp diseases” section says particle delivery systems increase drug penetration into hair follicle openings and act as a deposit for sustained release. It does not establish those effects specifically for nano-emulsions; the passage discusses particle systems more broadly. Page numbers are not available in our copy. (LLM, conf=0.84)

    Experimental — accuracy not yet measured
  • Nail cosmeceuticals based on nanotechnology have several benefits over traditional goods.

    “Nail cosmeceuticals based on nanotechnology have several benefits over traditional goods.”

    From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [85]

    The “Polymeric Micro and Nanoparticles” section lists several benefits of nanoparticles in dermocosmetics, including greater bioavailability and improved tolerance. The “History and Evolution” section mentions delivery through nails, but our copy does not establish that nail cosmeceuticals have these benefits over traditional nail products. No page numbers were provided for these passages. (LLM, conf=0.86)

    Experimental — accuracy not yet measured
  • Nail paints containing nanoparticles increase the toughness, impact resistance, and mar resistance of mammalian nails.

    “According to a study, nail paints containing nanoparticles increase the toughness, impact resistance, and mar resistance of mammalian nails.”

    From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [85]

    The “Innovations in cosmetics” section discusses nanoparticles in skin-care formulations, but not nanoparticle-containing nail paint or its effects on nails. Searches for nail paint, toughness, impact resistance, and mar or scratch resistance found no passage addressing the claim in our copy. (LLM, conf=0.73)

    Experimental — accuracy not yet measured

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 118

  1. [1]Bhushan B Springer handbook of nanotecnology 2nd ed Heidelberg, Germany Springer-Verlag 2007
  2. [2]Nasir A Nanodermatology: a glimpse of caution just beyond the horizon - part II Skin Therapy Lett 2010 15 4 7 20945053
  3. [3]Drexler KE Machine-phase nanotechnology Sci Am 2001 285 74 75 11524972
  4. [4]Drexler KE Nanosystems: molecular machinery, manufacturing, and computation New York John Wiley & Sons, Inc 1992
  5. [7]Nasir A Nanotechnology and dermatology: part I-potential of nanotechnology Clin Dermatol 2010 28 458 466 20620764
  6. [8]Saraceno R Chiricozzi A Gabellini M Chimenti S Emerging applications of nanomedicine in dermatology Skin Res Technol 2013 19 e13 e19 22175818
  7. [9]Friedman A Nasir A Nanotechnology and dermatology education in the United States: data from a pilot survey J Drugs Dermatol 2011 10 1037 1041 22052274
  8. [10]Papakostas D Rancan F Sterry W Blume-Peytavi U Vogt A Nanoparticles in dermatology Arch Dermatol Res 2011 303 533 550 21837474
  9. [11]Jung S Otberg N Thiede G Richter H Sterry W Panzner S et al Innovative liposomes as a transfollicular drug delivery system: penetration into porcine hair follicles J Invest Dermatol 2006 126 1728 1732 16645589
  10. [12]Peek LJ Middaugh CR Berkland C Nanotechnology in vaccine delivery Adv Drug Deliv Rev 2008 60 915 928 18325628 PMC7103321
  11. [13]de Vries JJ Bungener L Ter Veer W van Alphen L van der Ley P Wilschut J et al Incorporation of LpxL1, a detoxified lipopolysaccharide adjuvant, in influenza H5N1 virosomes increases vaccine immunogenicity Vaccine 2009 27 947 955 19059296
  12. [14]Ludwig C Wagner R Virus-like particles-universal molecular toolboxes Curr Opin Biotechnol 2007 18 537 545 18083549 PMC7126091
  13. [15]Mahe B Vogt A Liard C Duffy D Abadie V Bonduelle O et al Nanoparticlebased targeting of vaccine compounds to skin antigen-presenting cells by hair follicles and their transport in mice J Invest Dermatol 2009 129 1156 1164 19052565
  14. [16]Chirico F Fumelli C Marconi A Tinari A Straface E Malorni W et al Carboxyfullerenes localize within mitochondria and prevent the UVB-induced intrinsic apoptotic pathway Exp Dermatol 2007 16 429 436 17437486
  15. [17]Kato S Taira H Aoshima H Saitoh Y Miwa N Clinical evaluation of fullerene-C60 dissolved in squalane for antiwrinkle cosmetics J Nanosci Nanotechnol 2010 10 6769 6774 21137794
  16. [18]Villalonga-Barber C Micha-Screttas M Steele BR Georgopoulos A Demetzos C Dendrimers as biopharmaceuticals: synthesis and properties Curr Top Med Chem 2008 8 1294 1309 18855710
  17. [19]Venuganti VV Perumal OP Poly(amidoamine) dendrimers as skin penetration enhancers: Influence of charge, generation, and concentration J Pharm Sci 2009 98 2345 2356 18937369
  18. [20]Kristl J Teskac K Grabnar PA Current view on nanosized solid lipid carriers for drug delivery to the skin J Biomed Nanotechnol 2010 6 529 542 21329046
  19. [21]Saupe A Wissing SA Lenk A Schmidt C Müller RH Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC)-structural investigations on two different carrier systems Biomed Mater Eng 2005 15 393 402 16179760
  20. [22]Schäfer-Korting M Mehnert W Korting HC Lipid nanoparticles for improved topical application of drugs for skin diseases Adv Drug Deliv Rev 2007 59 427 443 17544165
  21. [23]Walther C Meyer K Rennert R Neundorf I Quantum dot-carrier peptide conjugates suitable for imaging and delivery applications Bioconjug Chem 2008 19 2346 2356 18991369
  22. [24]Zhou M Nakatani E Gronenberg LS Tokimoto T Wirth MJ Hruby VJ et al Peptidelabeled quantum dots for imaging GPCRs in whole cells and as single molecules Bioconjug Chem 2007 18 323 332 17373766
  23. [29]Barry BW Novel mechanisms and devices to enable successful transdermal drug delivery Eur J Pharm Sci 2001 14 101 114 11500256
  24. [30]Vogt A Mandt N Lademann J Schaefer H Blume-Peytavi U Follicular targeting-a promising tool in selective dermatotherapy J Investig Dermatol Symp Proc 12 2005 10 3 252 255 16382676
  25. [31]Kumar MN Kumar N Polymeric Controlled Drug-Delivery Systens: Perspective Issues and Opportunities Drug Dev Ind Pharm 1 2001 27 1 1 30 11247530
  26. [32]Embil K Nacht S The microsponge Delivery System (MDS): a topical delivery system with reduced irritancy incorporating multiple triggering mechanisms for the release of actives J Microencapsul 1996 13 575 588 8864994
  27. [34]Nacht S Encapsulation and other topical delivery systems: a review of the state-of-the-art for controlled topical delivery Cosmet Toiler 1995 110 25 30
  28. [35]Tran MA Watts RJ Robertson GP Use of liposomes as drug delivery vehicles for treatment of melanoma Pigment Cell Melanoma Res 2009 22 388 399 19493316 PMC2770731
  29. [36]Toll R Jacobi U Richter H Lademann J Schaefer H Blume-Peytavi U Penetration profile of microspheres in follicular targenting of terminal hair follicles J Invest Dermatol 2004 123 168 176 15191557
  30. [37]Rolland A Wagner N Chatelus A Shroot B Schaefer H Site-specific drug delivery to pilosebaceous strutures using polymeric microspheres Pharm Res 1993 10 1738 1744 8302759
  31. [38]Jenning V Gysler A Schäfer-Korting M Gohla SH Vitamin A loaded solid lipid nanoparticles for topical use: occlusive properties and drug targenting to the upper skin Eur J Pharm Biopharm 2000 49 211 218 10799811
  32. [39]Alvarez-Román R Naik A Kalia YN Guy RH Fessi H Enhancemente of topical delivery from biodegradable nanoparticles Pharm Res 2004 21 1818 1825 15553228
  33. [40]Freitas MN Marchetti JM Nimesulide PLA microspheres as a potencial sustained release system for the treatment of inflammatory diseases Int J Pharm 2005 295 201 211 15848005
  34. [43]Wang SQ Tooley IR Photoprotection in the era of nanotechnology Semin Cutan Med Surg 2011 30 210 213 22123418
  35. [44]Schilling K Bradford B Castelli D Dufour E Nash JF Pape W et al Human safety review of "nano" titanium dioxide and zinc oxide Photochem Photobiol Sci 2010 9 495 509 20354643
  36. [45]Tan MH Commens CA Burnett L Snitch PJ A pilot study on the percutaneous absorption of microfine titanium dioxide from sunscreens Australas J Dermatol 1996 37 185 187 8961584
  37. [46]Dussert AS Gooris E Hemmerle J Characterization of the mineral content of a physical sunscreen emulsion and its distribution onto human stratum corneum Int J Cosmet Sci 1997 19 119 129 18507639
  38. [47]Lademann J Weigmann H Rickmeyer C Barthelmes H Schaefer H Mueller G et al Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice Skin Pharmacol Appl Skin Physiol 1999 12 247 256 10461093
  39. [48]Schulz J Hohenberg H Pflücker F Gärtner E Will T Pfeiffer S et al Distribution of sunscreens on skin Adv Drug Deliv Rev 2002 54 Suppl 1 S157 S163 12460721
  40. [50]Cross SE Innes B Roberts MS Tsuzuki T Robertson TA McCormick P Human skin penetration of sunscreen nanoparticles: In-vitro assessment of a novel micronized zinc oxide formulation Skin Pharmacol Physiol 2007 20 148 154 17230054
  41. [51]Mavon A Miquel C Lejeune O Payre B Moretto P In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen Skin Pharmacol Physiol 2007 20 10 20 17035717
  42. [53]Zvyagin AV Zhao X Gierden A Sanchez W Ross JA Roberts MS Imaging of zinc oxide nanoparticle penetration in human skin in vitro and in vivo J Biomed Opt 2008 13 19123677
  43. [54]Sadrieh N Wokovich AM Gopee NV Zheng J Haines D Parmiter D et al Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano- and submicron-size TiO2 particles Toxicol Sci 2010 115 156 166 20156837 PMC2855360
  44. [55]Filipe P Silva JN Silva R Cirne de Castro JL Marques Gomes M Alves LC et al Stratum corneum is an effective barrier to TiO2 and ZnO nanoparticle percutaneous absorption Skin Pharmacol Physiol 2009 22 266 275 19690452
  45. [56]Durand L Habran N Henschel V Amighi K In vitro evaluation of the cutaneous penetration of sprayable sunscreen emulsions with high concentrations of UV filters Int J Cosmet Sci 2009 31 279 292 19496837
  46. [57]Johnston HJ Hutchison GR Christensen FM Peters S Hankin S Stone V Identification of the mechanisms that drive the toxicity of TiO2 particulates: The contribution of physicochemical characteristics Part Fibre Toxicol 2009 6 33 20017923 PMC2804608
  47. [58]Hirakawa K Mori M Yoshida M Oikawa S Kawanishi S Photo-irradiated titanium dioxide catalyzes site specific DNA damage via generation of hydrogen peroxide Free Radic Res 2004 38 439 447 15293551
  48. [59]Wamer WG Yin JJ Wei RR Oxidative damage to nucleic acids photosensitized by titanium dioxide Free Radic Biol Med 1997 23 851 858 9378364
  49. [60]Nakagawa Y Wakuri S Sakamoto K Tanaka N The photogenotoxicity of titanium dioxide particles Mutat Res 1997 394 125 132 9434851
  50. [62]Morganti P Use and potential of nanotechnology in cosmetic dermatology Clin Cosmet Investig Dermatol 2010 3 5 13 PMC3047942 21437055
  51. [64]Abramovits W Granowski P Arrazola P Applications of Nanomedicine in Dermatology: use of nanoparticles in various therapies and imaging J Cosmet Dermatol 2010 9 154 159 20618563
  52. [67]Percot A Viton C Domard A Optimization of chitin extraction from shrimp shell Biomacromolecules 2003 4 12 18 12523840
  53. [68]Muzzarelli RAA Mattioli-Belmonte M Pugnaloni A Biagini G Biochemistry, histology and clinical uses of chitins and chitosans in wound healing Jollés P Muzzarelli RAA Chitin and Chitinases Swizterland Birkhaüser Verlag 251 264 1999 10906965
  54. [71]Mezzana P Clinical efficacy of a new chitin-nanofibrils based gel in wound healing Acta Chir Plast 2008 50 81 84 19263641
  55. [72]Lademann J Richter H Golz K Zastrow L Sterry W Patzelt A Influence of microparticles on the homogeneity of distribution of topically applied substances Skin Pharmacol Physiol 2008 21 274 282 18663341
  56. [73]de Fine Olivarius F Hansen AB Karlsmark T Wulf HC Water protective effect of barrier creams and moisturizing creams: a new in vivo test method Contact Dermatitis 1996 35 219 225 8957641
  57. [74]Santos Maia C Mehnert W Schaller M Korting HC Gysler A Haberland A et al Drug targeting by solid lipid nanoparticles for dermal use J Drug Target 2002 10 489 495 12575739
  58. [75]Chen H Chang X Du D Liu W Liu J Weng T Yang Y et al Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting J Control Release 2006 110 296 306 16325954
  59. [76]Erdogan M Wright JR Jr McAlister VC Liposomal tacrolimus lotion as a novel topical agent for treatment of immune-mediated skin disorders: experimental studies in a murine model Br J Dermatol 2002 146 964 967 12072063
  60. [77]Egbaria K Ramachandran C Weiner N Topical application of liposomally entrapped cyclosporin evaluated by in vitro diffusion studies with human skin Skin Pharmacol 1991 4 21 28 2064787
  61. [78]Ali MF Salah M Rafea M Saleh N Liposomal methotrexate hydrogel for treatment of localized psoriasis: preparation,characterization and laser targeting Med Sci Monit 2008 14 PI66 PI74 19043379
  62. [79]Fang JY Fang CL Liu CH Su YH Lipid nanoparticles as vehicles for topical psoralen delivery: solid lipid nanoparticles (SLN) versus nanostructured lipid carriers (NLC) Eur J Pharm Biopharm 2008 70 633 640 18577447
  63. [80]Saraswat A Agarwal R Katare OP Kaur I Kumar B A randomized, double-blind, vehicle-controlled study of a novel liposomal dithranol formulation in psoriasis J Dermatolog Treat 2007 18 40 45 17365266
  64. [81]Lboutounne H Chaulet JF Ploton C Falson F Pirot F Sustained ex vivo skin antiseptic activity of chlorhexidine in poly(epsilon-caprolactone) nanocapsule encapsulated form and as a digluconate J Control Release 2002 82 319 334 12175746
  65. [82]Lboutounne H Faivre V Falson F Pirot F Characterization of transport of chlorhexidine-loaded nanocapsules through hairless and wistar rat skin Skin Pharmacol Physiol 2004 17 176 182 15258448
  66. [83]Harbarth S Pittet D Grady L Zawacki A Potter-Bynoe G Samore MH et al Interventional study to evaluate the impact of an alcohol-based hand gel in improving hand hygiene compliance Pediatr Infect Dis J 2002 21 489 495 12182370
  67. [84]Nhung DT Freydiere AM Constant H Falson F Pirot F Sustained antibacterial effect of a hand rub gel incorporating chlorhexdine-loaded nanocapsules (Nanochlorex) Int J Pharm 2007 334 166 172 17113253
  68. [85]Tsuang YH Sun JS Huang YC Lu CH Chang WH Wang CC Studies of photokilling of bacteria using titanium dioxide nanoparticles Artif Organs 2008 32 167 174 18269355
  69. [86]Chen X Schluesener HJ Nanosilver: a nanoproduct in medical application Toxicol Lett 2008 176 1 12 18022772
  70. [87]Pitsillides CM Joe EK Wei X Anderson RR Lin CP Selective cell targeting with light-absorbing microparticles and nanoparticles Biophys J 2003 84 4023 4032 12770906 PMC1302982
  71. [88]Dickerson EB Dreaden EC Huang X El-Sayed IH Chu H Pushpanketh S et al Gold nanorod assisted near-infrared plasmonic photothermal therapy (PPTT) of squamous cell carcinoma in mice Cancer Lett 2008 269 57 66 18541363 PMC3413727
  72. [89]El-Sayed IH Huang X El-Sayed MA Selective laser photo-thermal therapy of epithelial carcinoma using anti-EGFR antibody conjugated gold nanoparticles Cancer Lett 2006 239 129 135 16198049
  73. [90]Lu W Xiong C Zhang G Huang Q Zhang R Zhang JZ et al Targeted photothermal ablation of murine melanomas with melanocyte-stimulating hormone analogconjugated hollow gold nanospheres Clin Cancer Res 2009 15 876 886 19188158 PMC2727065
  74. [91]Henderson BW Dougherty TJ How does photodynamic therapy work? Photochem Photobiol 1992 55 145 157 1603846
  75. [92]Chatterjee DK Fong LS Zhang Y Nanoparticles in photodynamic therapy: an emerging paradigm Adv Drug Deliv Rev 2008 60 1627 1637 18930086
  76. [93]Rancan F Helmreich M Mölich A Ermilov EA Jux N Röder B et al Synthesis and in vitro testing of a pyropheophorbide-a-fullerene hexakis adduct immunoconjugate for photodynamic therapy Bioconjug Chem 2007 18 1078 1086 17550226
  77. [94]Khdair A Chen D Patil Y Ma L Dou QP Shekhar MP et al Nanoparticle-mediated combination chemotherapy and photodynamic therapy overcomes tumor drug resistance J Control Release 2010 141 137 144 19751777 PMC3763698
  78. [95]Taglietti M Hawkins CN Rao J Novel topical drug delivery systems and their potential use in acne vulgaris Skin Therapy Lett 2008 13 6 8 18648713
  79. [96]Patel VB Misra A Marfatia YS Topical liposomal gel of tretinoin for the treatment of acne: research and clinical implications Pharm Dev Technol 2000 5 455 464 11109245
  80. [97]Queille-Roussel C Poncet M Mesaros S Clucas A Baker M Soloff AM Comparison of the cumulative irritation potential of adapalene gel and cream with that of erythromycin/tretinoin solution and gel and erythromycin/isotretinoin gel Clin Ther 2001 23 205 212 11293554
  81. [99]Castro GA Oliveira CA Mahecha GA Ferreira LA Comedolytic effect and reduced skin irritation of a new formulation of all-trans retinoic acid-loaded solid lipid nanoparticles for topical treatment of acne Arch Dermatol Res 2011 303 513 520 21298279
  82. [100]Bernard E Dubois JL Wepierre J Importance of sebaceous glands in cutaneous penetration of an antiandrogen: target effect of liposomes J Pharm Sci 1997 86 573 578 9145381
  83. [101]Münster U Nakamura C Haberland A Jores K Mehnert W Rummel S et al RU 58841-myristate-prodrug development for topical treatment of acne and androgenética alopecia Pharmazie 2005 60 8 12 15700772
  84. [102]Bikowski J Del Rosso JQ Benzoyl peroxide microsphere cream as monotherapy and combination treatment of acne J Drugs Dermatol 2008 7 590 595 18561594
  85. [103]Tsujimoto H Hara K Tsukada Y Huang CC Kawashima Y Arakaki M et al Evaluation of the permeability of hair growing ingredient encapsulated PLGA nanospheres to hair follicles and their hair growing effects Bioorg Med Chem Lett 2007 17 4771 4777 17658251
  86. [104]Shim J Seok Kang H Park WS Han SH Kim J Chang IS Transdermal delivery of mixnoxidil with block copolymer nanoparticles J Control Release 2004 97 477 484 15212879
  87. [105]Jain B Singh B Katare OP Vyas SP Development and characterization of minoxidil-loaded liposomal system for delivery to pilosebaceous units J Liposome Res 2010 20 105 114 19698000
  88. [106]Kumar R Singh B Bakshi G Katare OP Development of liposomal systems of finasteride for topical applications: design, characterization, and in vitro evaluation Pharm Dev Technol 2007 12 591 601 18161632
  89. [107]Vogt A Combadiere B Hadam S Stieler KM Lademann J Schaefer H 40 nm.but not 750 or 1.500 nm.nanoparticles enter epidermal CD1a+ cells after transcutaneous application on human skin J Invest Dermatol 2006 126 1316 1322 16614727
  90. [108]Nakamura M Jo J Tabata Y Ishikawa O Controlled delivery of T-box21 small interfering RNA ameliorates autoimmune alopecia (alopecia areata) in a C3H/HeJ mouse model Am J Pathol 2008 172 650 658 18245811 PMC2258260
  91. [109]Ahmed N et al Theranostic applications of nanoparticles in câncer Drug Discov Today 2012 17 928 934 22484464
  92. [110]Persidis A Cancer multidrug resistance Nat Biotechnol 1999 17 94 95 9920278
  93. [111]Parveen S Sahoo SK Nanomedicine: clinical applications of polyethylene glycol conjugated proteins and drugs Clin Pharmacokinet 2006 45 965 988 16984211
  94. [112]Sahoo SK Parveen S Panda JJ The present and future of nanotechnology in human health care Nanomedicine 2007 3 20 31 17379166
  95. [113]Boye J Elter T Engert A An overview of the current clinical use of the anti-CD20 monoclonal antibody rituximab Ann Oncol 2003 14 520 535 12649096
  96. [114]Plosker GL Figgitt DP Rituximab: a review of its use in non- Hodgkin's lymphoma and chronic lymphocytic leukaemia Drugs 2003 63 803 843 12662126
  97. [115]Coiffier B Lepage E Briere J Herbrecht R Tilly H Bouabdallah R et al CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma N Engl J Med 2002 346 235 242 11807147
  98. [116]Elder D Tumor progression, early diagnosis and prognosis of melanoma Acta Oncol 1999 38 535 547 10427941
  99. [117]Garbe C Eigentler TK Diagnosis and treatment of cutaneous melanoma: state of the art 2006 Melanoma Res 2007 17 117 127 17496787
  100. [118]Guerry 4th D Synnestvedt M Elder DE Schultz D Lessons from tumor progression: the invasive radial growth phase of melanoma is common, incapable of metastasis, and indolent J Invest Dermatol 1993 100 342S 345S 8440920
  101. [119]Wang MD Shin DM Simons JW Nie S Nanotechnology for targeted cancer therapy Expert Rev Anticancer Ther 2007 7 833 837 17555393
  102. [120]Solanki A Kim JD Lee KB Nanotechnology for regenerative medicine: nanomaterials for stem cells imaging Nanomedicine (Lond) 2008 3 567 578 18694318
  103. [122]Souza KC Salazar-Alvarez G Ardisson JD Macedo WA Sousa EM Mesoporous silica-magnetite nanocomposite synthesized by using a neutral surfactant Nanotechnology 2008 19 185603 21825691
  104. [123]Jain KK Nanotechnology in clinical laboratory diagnostics Clin Chim Acta 2005 358 37 54 15890325
  105. [124]Olafsson R Bauer DR Montilla LG Witte RS Realtime, contrast enhanced photoacoustic imaging of cancer in a mouse window chamber Opt Express 2010 18 18625 18632 20940754
  106. [125]Hia J Nasir A Photonanodermatology: the interface of photobiology, dermatology and nanotechnology Photodermatol Photoimmunol Photomed 2011 27 2 9 21198876
  107. [127]Lim JK Majetich SA Tilton RD Stabilization of superparamagnetic iron oxide coregold shell nanoparticles in high ionic strength media Langmuir 2009 25 13384 13393 19928938
  108. [128]Kamei K Mukai Y Kojima H Yoshikawa T Yoshikawa M Kiyohara G et al Direct cell entry of gold/iron-oxide magnetic nanoparticles in adenovirus mediated gene delivery Biomaterials 2009 30 1809 1814 19136151
  109. [129]Kohler N Sun C Wang J Zhang M Methotrexate-modified superparamagnetic nanoparticles and their intracellular uptake into human cancer cells Langmuir 2005 21 8858 8864 16142971
  110. [130]Yu MK Jeong YY Park J Park S Kim JW Min JJ Drug-loaded superparamagnetic iron oxide nanoparticles for combined cancer imaging and therapy in vivo Angew Chem Int Ed Engl 2008 47 5362 5365 18551493
  111. [131]Melancon MP Lu W Zhong M Zhou M Liang G Elliott AM et al Targeted multifunctional gold-based nanoshells for magnetic resonance-guided laser ablation of head and neck cancer Biomaterials 2011 32 7600 7608 21745689 PMC3195359
  112. [132]Yang X Grailer JJ Rowland IJ Javadi A Hurley SA Steeber DA et al Multifunctional SPIO/DOX-loaded wormlike polymer vesicles for cancer therapy and MR imaging Biomaterials 2010 31 9065 9073 20828811
  113. [133]Parhi P Mohanty C Sahoo SK Nanotechnology-based combinational drug delivery: an emerging approach for cancer therapy Drug Discov Today 2012 17 1044 1052 22652342
  114. [135]Nel A Xia T Meng H Wang X Lin S Ji Z et al Nanomaterial toxicity testing in the 21st century: use of a predictive toxicological approach and high-throughput Acc Chem Res 2013 46 607 621 22676423 PMC4034475
  115. [136]Nel A Xia T Mädler L Li N Toxic potential of materials at the nanolevel Science 2006 311 622 627 16456071
  116. [137]Nel AE Mädler L Velegol D Xia T Hoek EM Somasundaran P et al Understanding biophysicochemical interactions at the nanobio interface Nat Mater 2009 8 543 557 19525947
  117. [138]George S Pokhrel S Xia T Gilbert B Ji Z Schowalter M, A et al Use of a rapid cytotoxicity screening approach to engineer a safer zinc oxide nanoparticle through iron doping ACS Nano 2010 4 15 29 20043640 PMC3900637
  118. [139]Mura S Couvreur P Nanotheranostics for personalized medicine Adv Drug Deliv Rev 2012 64 1394 1416 22728642

Cited by

Sorted by citations

Authors
Antonio, J. R., Antonio, C. R., Cardeal, I. L. S., Ballavenuto, J. M. A., & Oliveira, J. R.
Affiliations
  • Sao Jose do Rio Preto State School of Medicine, Brazil
  • Faculdade de Medicina de São José do Rio Preto (BR)
Venue
Anais Brasileiros de Dermatologia
Published
2014-01
Volume
89
Issue
1
Pages
126-136
ISSN
0365-0596 (ISSN-L)
OpenAlex
W2072636091
Cited by
107
References
2
Citations by year
2026: 1 · 2025: 11 · 2024: 6 · 2023: 13 · 2022: 11 · 2021: 11 · 2020: 12 · 2019: 7 · 2018: 10 · 2017: 4 · 2016: 11 · 2015: 8 · 2014: 2
FWCI
0.72
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • Anais Brasileiros de Dermatologia (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • University of Birmingham Research Portal (University of Birmingham) (publishedVersion, other-oa)
  • LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
  • Americanae (AECID Library) (submittedVersion, cc-by-nc)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Faculdade de Medicina de São José do Rio Preto
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Nanotechnology research and applications
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Drug Discovery › Pharmacology and Nanomedicine Research
Keywords
nanotechnology, dermatology, nanomedicine, interdisciplinary research, chemical knowledge, research funding
MeSH terms
Dermatology, Humans, Skin Diseases, Drug Delivery Systems, Nanomedicine, Nanoparticles

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review