Tratamento de curto prazo com liraglutide no reganho de peso após cirurgia bariátrica
Open accessAbstract
OBJETIVO: avaliar os resultados da utilização do liraglutide em um grupo de pacientes submetidos ao tratamento cirúrgico da obesidade mórbida com perda insatisfatória de peso ou ganho de mais de 15% do seu peso mínimo atingido. MÉTODOS: realizou-se análise retrospectiva de 15 pacientes operados que tiveram perda de excesso de peso <50% após dois anos de seguimento ou reganho de peso de mais de 15% do peso mínimo atingido. Foram incluídos apenas pacientes que apresentavam a "anatomia cirúrgica" normal avaliada por radiografia contrastada e endoscopia digestiva alta. A média de idade foi 47,2±12,5 anos e os pacientes receberam liraglutide na dose de 1,2 a 3,0mg/dia por oito a 28 semanas de seguimento. RESULTADOS: o tratamento cirúrgico induziu uma perda de peso de 34,1± 16,5Kg. A média de reganho de peso após 5,3 ±3,3 anos foi 14,2±12,1Kg. A media de peso reduziu significativamente após o tratamento com liraglutide (100,9±18,3Kg vs. 93,5±17,4Kg; p<0,0001). Seis pacientes apresentaram náuseas e dois descontinuaram o tratamento em decorrência do custo da medicação. CONCLUSÃO: o tratamento clínico medicamentoso dirigido para o controle da saciedade com o uso do liraglutide pode ser uma alternativa para manejo dos pacientes com reganho de peso ou perda insuficiente após o tratamento cirúrgico, quando nenhum problema técnico tenha sido identificado.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Most reports on GLP1-RA efficacy in patients with weight regain after bariatric surgery are limited to liraglutide and come from observational studies or case reports.
“Reports on the efficacy of GLP1-RAs in patients with weight regain after bariatric surgery are mostly limited to liraglutide in observational studies or case reports [9–20].”
The role of GLP1-RAs in treating weight regain after bariatric surgery is still not defined.
“Their role in the treatment of weight regain after bariatric surgery remains to be defined.”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Martin, R. (1986) · Medical Entomology and Zoology · Cited by 8,743 · see citing works
Astrup, A., Rössner, S., Van Gaal, L., Rissanen, A., Niskanen, L., Al Hakim, M., Madsen, J., Rasmussen, M. F., & Lean, M. E. (2009) · The Lancet · doi:10.1016/s0140-6736(09)61375-1 · Cited by 1,163 · see citing works
Heber, D., Greenway, F. L., Kaplan, L. M., Livingston, E., Salvador, J., & Still, C. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2128 · Cited by 521 · see citing works
Behavioral predictors of weight regain after bariatric surgery
Odom, J., Zalesin, K. C., Washington, T. L., Miller, W. W., Hakmeh, B., Zaremba, D. L., Altattan, M., Balasubramaniam, M., Gibbs, D. S., Krause, K. R., et al. (2010) · Obesity Surgery · doi:10.1007/s11695-009-9895-6 · Cited by 483 · see citing works
Mechanick, J. I., Kushner, R. F., Sugerman, H. J., González-Campoy, J. M., Collazo–Clavell, M. L., Guven, S., Spitz, A. F., Apovian, C. M., Livingston, E. H., Brolin, R. E., et al. (2008) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2008.08.009 · Cited by 372 · see citing works
Bariatric surgery and reduction in morbidity and mortality: experiences from the SOS study
Sjöström, L. (2008) · International Journal of Obesity · doi:10.1038/ijo.2008.244 · Cited by 349 · see citing works
Weight regain after Roux-en-Y: A significant 20% complication related to PYY
Meguid, M. M., Glade, M. J., & Middleton, F. A. (2008) · Nutrition · doi:10.1016/j.nut.2008.06.027 · Cited by 140 · see citing works
Effect of gastric bypass surgery on the incretins
Laferrère, B. (2009) · Diabetes & Metabolism · doi:10.1016/s1262-3636(09)73458-5 · Cited by 89 · see citing works
Kellogg, T. A. (2011) · Surgical Clinics of North America · doi:10.1016/j.suc.2011.08.004 · Cited by 83 · see citing works
Zilberstein, B., Pajecki, D., de Brito, A. C. G., Gallafrio, S. T., Eshkenazy, R., & Andrade, C. G. (2004) · Obesity Surgery · doi:10.1381/0960892041590926 · Cited by 59 · see citing works
Self-citationLiraglutide for the treatment of type 2 diabetes
Shyangdan, D., Cummins, E., Royle, P., & Waugh, N. R. (2011) · Health Technology Assessment · doi:10.3310/hta15suppl1/09 · Cited by 35 · see citing works
Coleman, K. J., Toussi, R., & Fujioka, K. (2010) · Obesity Surgery · doi:10.1007/s11695-010-0223-y · Cited by 34 · see citing works
Zoss, I., Piec, G., & Horber, F. F. (2002) · Obesity Surgery · doi:10.1381/096089202321144685 · Cited by 34 · see citing works
Rothkopf, M. M., Bilof, M. L., Haverstick, L. P., & Nusbaum, M. J. (2009) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2008.09.005 · Cited by 15 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Rev. Col. Bras. Cir. 2012; 40(3): 191-195
Cited by
Sorted by citations
Garvey, W. T., Mechanick, J. I., Brett, E. M., Garber, A. J., Hurley, D. L., Jastreboff, A. M., Nadolsky, K., Pessah-Pollack, R., & Plodkowski, R. (2016) · Endocrine Practice · doi:10.4158/ep161365.gl · Cited by 1,914 · see citing works
Miras, A. D., Pérez-Pevida, B., Aldhwayan, M., Kamocka, A., McGlone, E. R., Al-Najim, W., Chahal, H., Batterham, R. L., McGowan, B., Khan, O., et al. (2019) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(19)30157-3 · Cited by 190 · see citing works
Jensen, A. B., Renström, F., Aczél, S., Folie, P., Biraima-Steinemann, M., Beuschlein, F., & Bilz, S. (2023) · Obesity Surgery · doi:10.1007/s11695-023-06484-8 · Cited by 161 · see citing works
Rye, P., Modi, R., Cawsey, S., & Sharma, A. M. (2018) · Obesity Surgery · doi:10.1007/s11695-018-3393-7 · Cited by 97 · see citing works
Lautenbach, A., Wernecke, M., Huber, T. B., Stoll, F., Wagner, J., Meyhöfer, S. M., Meyhöfer, S., & Aberle, J. (2022) · Obesity Surgery · doi:10.1007/s11695-022-06211-9 · Cited by 92 · see citing works
The limits and challenges of antiobesity pharmacotherapy
Gadde, K. M., & Atkins, K. D. (2020) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2020.1748599 · Cited by 65 · see citing works
Gorgojo-Martínez, J. J., Feo-Ortega, G., & Serrano-Moreno, C. (2016) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2016.02.013 · Cited by 60 · see citing works
Toth, A. T., Gomez, G., Shukla, A. P., Pratt, J. S., Cena, H., Biino, G., Aronne, L. J., & Stanford, F. C. (2018) · Children · doi:10.3390/children5090116 · Cited by 57 · see citing works
Pharmacotherapies for post-bariatric weight regain: real-world comparative outcomes
Gazda, C. L., Clark, J. D., Lingvay, I., & Almandoz, J. P. (2021) · Obesity · doi:10.1002/oby.23146 · Cited by 56 · see citing works
Pharmacotherapy for Obesity—Trends Using a Population Level National Database
Elangovan, A., Shah, R., & Smith, Z. L. (2021) · Obesity Surgery · doi:10.1007/s11695-020-04987-2 · Cited by 56 · see citing works
Use of weight loss medications in patients after bariatric surgery.
Redmond, I. P., Shukla, A. P., & Aronne, L. J. (2021) · Current Obesity Reports · doi:10.1007/s13679-021-00425-1 · Cited by 50 · see citing works
Elhag, W., & El Ansari, W. (2022) · Obesity Surgery · doi:10.1007/s11695-021-05884-y · Cited by 49 · see citing works
Current concepts in management of weight regain following bariatric surgery
Shukla, A. P., He, D., Saunders, K. H., Andrew, C., & Aronne, L. J. (2018) · Expert Review of Endocrinology & Metabolism · doi:10.1080/17446651.2018.1447922 · Cited by 49 · see citing works
Pharmacologic management of weight regain following bariatric surgery.
Lucas, E., Simmons, O., Tchang, B., & Aronne, L. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.1043595 · Cited by 41 · see citing works
Glucagon-Like Peptide 1 Receptor Agonists: A Medication for Obesity Management
Taha, M. B., Yahya, T., Satish, P., Laird, R., Agatston, A. S., Cainzos-Achirica, M., Patel, K. V., & Nasir, K. (2022) · Current Atherosclerosis Reports · doi:10.1007/s11883-022-01041-7 · Cited by 31 · see citing works
- Authors
- Pajecki, D., Halpern, A., Cercato, C., Mancini, M., Cleva, R. D., & Santo, M. A.
- Affiliations
- Universidade de São Paulo (BR)
- Venue
- Revista do Colégio Brasileiro de Cirurgiões
- Publisher
- FapUNIFESP (SciELO)
- Published
- 2013-06
- Volume
- 40
- Issue
- 3
- Pages
- 191-195
- ISSN
- 0100-6991 (ISSN-L)
- OpenAlex
- W2049384527
- Cited by
- 93
- References
- 14
- Citations by year
- 2026: 6 · 2025: 11 · 2024: 16 · 2023: 12 · 2022: 9 · 2021: 8 · 2020: 8 · 2019: 7 · 2018: 6 · 2017: 4 · 2016: 6
- FWCI
- 1.97
- Type
- journal article
- Language
- pt
- Open access
- gold
- doi.org
- Licence
- cc-by-nc
- Locations
- Revista do Colégio Brasileiro de Cirurgiões (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
- Americanae (AECID Library) (submittedVersion, cc-by-nc)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Pharmacology › Pharmacology and Obesity Treatment
- Health Sciences › Medicine › Surgery › Body Contouring and Surgery
- Keywords
- liraglutide, bariatric surgery, morbid obesity, weight regain, weight loss, GLP-1 receptor agonists
- MeSH terms
- Liraglutide, Female, Humans, Male, Middle Aged, Obesity, Morbid, Retrospective Studies, Time Factors, Weight Gain, Treatment Failure, Bariatric Surgery, Glucagon-Like Peptide 1
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
