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Effect of ethyl acetate extract from husk fiber water of Cocos nucifera in Leishmania braziliensis infected hamsters
Open accessAbstract
The objective of this study was to evaluate the treatment with ethyl acetate extract (EAE) from husk fiber water of Cocos nucifera L., Arecaceae, in L. braziliensis (Lb) infected hamsters. Twelve male hamsters were randomly allocated in three groups (n=4): G1 received only EAE; G2 was infected with Lb only and G3 received EAE after Lb infection. The infection was carried 28 days prior to the treatment with EAE, which was administrated (0.2 mL, 300 mg.kg-1) for 21 consecutive days. Infection was evaluated through skin lesions and infected footpad edema. Haematological evaluation was done on -28th, 0 and 21st days. Imprint footpad and lymph node weight were evaluated on 21st day. Lb infection significantly inhibited the peripheral leukocytes blood. However, neutrophils and lymphocytes values did not have significant alterations. G3 presented eosinophilia in relation to G2. The treatment with EAE did not reduce edema of infected footpad neither weight of drainage lymph node. Infected footpad imprints revealed amastigotes forms and cellular infiltration. Animals from G3 presented skin lesions on 7th day, shown a reduction of these lesions in day 14. Therefore, the treatment with EAE did not alter the etiological agent elimination in these conditions. However, EAE presents a healing activity in this experimental model.
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“The lyophilized extract and fractions, as well as ethyl acetate extracts, from the C. nucifera fiber are rich in polyphenols, compounds such as catechins, epicatechins, tannins, and flavonoids (7,33–35).”
From Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review (2015) · cites this paper as [35]
In the citing paper
“Administering EAE (0.2 mL, 300 mg/kg) for 21 consecutive days did not reduce edema of infected footpad nor the weight of lymph node drainage but reduced skin lesions after 14 days.”
From Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review (2015) · cites this paper as [35]
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Esquenazi, D., Wigg, M. D., Miranda, M. M. F. S., Rodrigues, H. M., Tostes, J. B. F., Rozental, S., da Silva, A. J. R., & Alviano, C. S. (2002) · Research in Microbiology · doi:10.1016/s0923-2508(02)01377-3 · Cited by 291
Ashford, D. A., David, J. R., Freire, M., David, R., Sherlock, I. A., Eulalio, M., Pedral-Sampaio, D., & Badaró, R. J. D. S. (1998) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.1998.59.53 · Cited by 189
Mendonça-Filho, R. R., Rodrigues, I. A., Alviano, D. S., Santos, A. L. S., Soares, R. M. A., Alviano, C. S., Lopes, A. H. C. S., & do Socorro S. Rosa, M. (2004) · Research in Microbiology · doi:10.1016/j.resmic.2003.12.001 · Cited by 115
Inhibitory activity of limonene against Leishmania parasites in vitro and in vivo
Arruda, D. C., Miguel, D. C., Yokoyama-Yasunaka, J. K. U., Katzin, A. M., & Uliana, S. R. B. (2009) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2009.02.004 · Cited by 105
Evaluation of the leishmanicidal activity of plants used by Peruvian Chayahuita ethnic group
Estevez, Y., Castillo, D., Tangoa, M. P., Arévalo, J., Rojas, R., Castillo, J. A., Deharo, E., Bourdy, G., & Sauvain, M. (2007) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2007.08.007 · Cited by 99
Pereira, B. A. S., & Alves, C. R. (2008) · Veterinary Parasitology · doi:10.1016/j.vetpar.2008.09.015 · Cited by 91
Antileishmanial activities associated with plants used in the Malian traditional medicine
Ahua, K. M., Ioset, J., Ioset, K. N., Diallo, D., Mauël, J., & Hostettmann, K. (2006) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2006.09.030 · Cited by 83
Patrício, F. J. B., Costa, G. C., Pereira, P. V. S., Aragão-Filho, W. C., Sousa, S. M., Frazão, J. B., Pereira, W. S., Maciel, M. C. G., Silva, L. A., do Amaral, F. M. M., et al. (2007) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2007.10.009 · Cited by 67
Self-citationAlviano, D. S., Rodrigues, K. F., Leitão, S. G., Rodrigues, M. L., Matheus, M. E., Fernandes, P. D., Antoniolli, Â. R., & Alviano, C. S. (2004) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2004.03.013 · Cited by 60
Simões-Mattos, L., Mattos, M. R. F., Teixeira, M. J., Oliveira-Lima, J. W., Bevilaqua, C. M. L., Prata-Júnior, R. C., Holanda, C. M. D. C. X., Rondon, F. C. M., Bastos, K. M. S., Coêlho, Z. C. B., et al. (2004) · Veterinary Parasitology · doi:10.1016/j.vetpar.2004.10.008 · Cited by 54
Singh, N., Kumar, A., Gupta, P., Chand, K., Samant, M., Maurya, R., & Dube, A. (2007) · Parasitology Research · doi:10.1007/s00436-007-0822-2 · Cited by 45
Lamidi, M., Giorgio, C. D., Delmas, F., Favel, A., Mve-Mba, C. E., Rondi, M.-L., Ollivier, É., Nze-Ekekang, L., & Balansard, G. (2005) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2005.06.011 · Cited by 44
Alviano, D. S. (2004) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(04)00121-7 · Cited by 10
Research works printed but not linked: 1
- Duke JA 1992. Handbook of phytochemical constituents of Grãs Herbs and other economic plants. CRC Press: Boca Raton.
Cited by
Sorted by citations
Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review
Lima, E. B. C., Sousa, C. N. S., Meneses, L. N., Ximenes, N. C., Santos Júnior, M. A., Vasconcelos, G. S., Lima, N. B. C., Patrocínio, M. C. A., Macedo, D., & Vasconcelos, S. M. M. (2015) · Brazilian Journal of Medical and Biological Research · doi:10.1590/1414-431x20154773 · Cited by 295
Roopan, S. M. (2016) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-016-2067-y · Cited by 53
Singla, R. K., & Dubey, A. K. (2018) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/1871530319666181128100206 · Cited by 27
Parmar, P., Singh, A. K., & Borad, S. G. (2020) · Springer eBooks · doi:10.1007/978-981-15-4194-0_7 · Cited by 18
Plant-Derived Natural Products for the Treatment of Leishmaniasis
(2013) · Studies in natural products chemistry · doi:10.1016/b978-0-444-62615-8.00011-4 · Cited by 12
Metadata
- Authors
- Freitas, J. C. C., Nunes-Pinheiro, D. C. S., Pessoa, A. W. P., Silva, L. C. R., Girão, V. C. C., Lopes-Neto, B. E., Agostinho, M. S., & Abreu, C. R. A.
- Affiliations
- Universidade Estadual do Ceará (BR)
- Venue
- Revista Brasileira de Farmacognosia
- Published
- 2011-12
- Volume
- 21
- Issue
- 6
- Pages
- 1006-1011
- ISSN
- 0102-695X (ISSN-L)
- OpenAlex
- W1569289873
- Cited by
- 14
- References
- 12
- Citations by year
- 2023: 2 · 2022: 4 · 2021: 1 · 2020: 3 · 2018: 1 · 2016: 1 · 2015: 1 · 2013: 1
- FWCI
- 0.31
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc-nd
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- Locations
- Revista Brasileira de Farmacognosia (publishedVersion, cc-by-nc-nd)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
- Americanae (AECID Library) (submittedVersion, cc-by-nc-nd)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Research on Leishmaniasis Studies
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry Medicinal Plant Applications
- Life Sciences › Agricultural and Biological Sciences › Food Science › Coconut Research and Applications
- Keywords
- Cocos nucifera, ethyl acetate extract, Leishmania braziliensis, cutaneous leishmaniasis, antileishmanial activity, wound healing, skin lesions, eosinophilia, peripheral blood leukocytes, lymph node weight, amastigotes, hamster model
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