The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Preparation, characterization and evaluation of moisturizing and UV protecting effects of topical solid lipid nanoparticles
Open accessAbstract
Solid lipid nanoparticles (SLN) were recently proposed as carriers for various pharmaceutical and cosmetic actives. These lipid nanoparticles can act as moisturizers and physical sunscreens on their own. Therefore, the full potential of these carriers has yet to be determined. The present study was aimed to determine and compare moisturizing and UV-protecting effects of different solid lipid nanoparticles (SLN) prepared by different solid lipids including Glyceryl monostearate (GMS), Precirol® (P) and cetyl palmitate (CP) as carrier systems of moisturizers and sunscreens. The influence of the size and matrix crystallinity of the solid lipids on the occlusive factor, skin hydration and UV-protection were evaluated by in vitro and in vivo methods. The SLN were prepared by high-shear homogenization and ultrasound methods. Size, zeta potential and morphological characteristics of the samples were assessed by transmission electron microscopy (TEM) and thermotropic properties with differential scanning calorimetry (DSC) technique. Results of the assessments showed that SLN-CP significantly increases skin hydration and UV-protection, compared to SLN-GMS and SLN-P. It was demonstrated that the size of SLN, crystallinity index of solid lipid in SLN and probably other mechanisms besides the occlusive factor can influence skin hydration and UV-protection indices. Furthermore, findings of the assessments demonstrated significant difference between in vitro and in vivo assessments regarding occlusive factor and moisturizing effects. Findings of the present study indicate that the SLN-CP could be a promising carrier for sunscreens and moisturizers.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Particularly, soy isoflavones deposited in the dermal matrix were found to be more effective and exhibits greater penetration into the stratum cornea when they were in the form of solid lipid nanoparticles [81, 82].”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [81]
In the citing paper
“However, improved skin biocompatibility, enhanced photoaging, and enhanced anti-aging potential were demonstrated by biocompatible nano-lipoidal carriers of isotretinoin.”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [81]
Citations
Cites
Solid lipid nanoparticles (SLN) for controlled drug delivery – a review of the state of the art
Müller, R. (2000) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(00)00087-4 · Cited by 3,836
Solid lipid nanoparticles (SLN) for controlled drug delivery – Drug release and release mechanism
Mühlen, A. Z., Schwarz, C., & Mehnert, W. (1998) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(97)00150-1 · Cited by 945
Particle size of liposomes influences dermal delivery of substances into skin
Verma, D. K. (2003) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(03)00183-2 · Cited by 704
Souto, E. B., Wissing, S. A., Barbosa, C. M., & Müller, R. H. (2004) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2004.02.032 · Cited by 692
Preparation, characterization and in vitro release kinetics of clozapine solid lipid nanoparticles
Venkateswarlu, V., & Manjunath, K. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.01.005 · Cited by 565
The production and characteristics of solid lipid nanoparticles (SLNs)
Hou, D., Xie, C., Huang, K., & Zhu, C. (2003) · Biomaterials · doi:10.1016/s0142-9612(02)00578-1 · Cited by 439
Solid lipid nanoparticles as carrier for sunscreens: in vitro release and in vivo skin penetration
Wissing, S. A., & Müller, R. H. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(02)00056-1 · Cited by 405
Isotretinoin-loaded solid lipid nanoparticles with skin targeting for topical delivery
Liu, J., Hu, W. S., Chen, H., Ni, Q., Xu, H., & Yang, X. (2006) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2006.08.007 · Cited by 384
Cosmetic applications for solid lipid nanoparticles (SLN)
Wissing, S. A. (2003) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(02)00684-1 · Cited by 366
Kullavanijaya, P., & Lim, H. W. (2005) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2004.07.063 · Cited by 356
Flagged first, then by citations
Research works printed but not linked: 1
- MULLER R.H., 2000, The next generation after the liposomes: solid lipid nanoparticles (SLNe, Lipopearlse) as dermal carrier in cosmetics, Eurocosmetics, 7, 19
Cited by
Sorted by citations
Nanostructured Lipid Carriers: A Groundbreaking Approach for Transdermal Drug Delivery
Chauhan, I., Yasir, M., Verma, M., & Singh, A. P. (2020) · Advanced Pharmaceutical Bulletin · doi:10.34172/apb.2020.021 · Cited by 527
Severino, P. B., Silveira, E. F., Loureiro, K. C., Chaud, M. V., Antonini, D., Lancellotti, M., Sarmento, V. H. V., da Silva, C. F., Santana, M. H. A., & Souto, E. B. (2017) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2017.05.063 · Cited by 88
Khameneh, B., Halimi, V., Jaafari, M. R., & Golmohammadzadeh, S. (2015) · Europe PMC (PubMed Central) · Cited by 58
Self-citationRodrigues, L. R., & Jose, J. (2020) · Environmental Science and Pollution Research · doi:10.1007/s11356-020-08543-4 · Cited by 63
Nanotechnology application on bamboo materials: A review
Sun, H., Li, X., Li, H., Hui, D., Gaff, M., & Lorenzo, R. (2022) · Nanotechnology Reviews · doi:10.1515/ntrev-2022-0101 · Cited by 43
Metadata
- Authors
- Golmohammadzadeh, S., Mokhtari, M., & Jaafari, M. R.
- Affiliations
- Mashhad University of Medical Sciences (IR)
- Venue
- Brazilian Journal of Pharmaceutical Sciences
- Publisher
- FapUNIFESP (SciELO)
- Published
- 2012-12
- Volume
- 48
- Issue
- 4
- Pages
- 683-690
- ISSN
- 1984-8250 (ISSN-L)
- OpenAlex
- W2109755040
- Cited by
- 28
- References
- 31
- Citations by year
- 2025: 1 · 2023: 2 · 2022: 4 · 2021: 1 · 2020: 8 · 2019: 5 · 2018: 1 · 2017: 1 · 2016: 3 · 2015: 1 · 2013: 1
- FWCI
- 0.40
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by-nc
- Locations
- Brazilian Journal of Pharmaceutical Sciences (publishedVersion, cc-by-nc)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
- Americanae (AECID Library) (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, cc-by)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Keywords
- solid lipid nanoparticles, emollients, physical sunscreens, UV protection, skin hydration, cetyl palmitate, glyceryl monostearate, Precirol, nanoparticle size, high shear homogenization, topical drug delivery
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
