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Cited by 367

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Plasticity of Bone Marrow–Derived Stem Cells

Grove, Joanna E., Bruscia, Emanuela, Krause, Diane S.·2004·STEM CELLS

Abstract

Stem cell plasticity refers to the ability of adult stem cells to acquire mature phenotypes that are different from their tissue of origin. Adult bone marrow cells (BMCs) include two populations of bone marrow stem cells (BMCs): hematopoietic stem cells (HSCs), which give rise to all mature lineages of blood, and mesenchymal stem cells (MSCs), which can differentiate into bone, cartilage, and fat. In this article, we review the literature that lends credibility to the theory that highly plastic BMCs have a role in maintenance and repair of nonhematopoietic tissue. We discuss the possible mechanisms by which this may occur. Also reviewed is the possibility that adult BMCs can change their gene expression profile after fusion with a mature cell, which has brought into question whether this stem cell plasticity is real.

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Crossref · 10.1634/stemcells.22-4-487

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Metadata

Authors
Grove, J. E., Bruscia, E., & Krause, D. S.
Venue
STEM CELLS
Published
2004-07
Volume
22
Issue
4
Pages
487-500
ISSN
  • 1066-5099 (ISSN-L)
  • 1549-4918
OpenAlex
W2110918038
Cited by
367
References
5
FWCI
19.16
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Plasticity of Bone Marrow–Derived Stem Cells. https://app.cochat.ai/papers/10.1634/stemcells.22-4-487
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Grove, J. E., Bruscia, E., & Krause, D. S. (2004). Plasticity of Bone Marrow–Derived Stem Cells. STEM CELLS. https://doi.org/10.1634/stemcells.22-4-487

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.