The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Immediate Postoperative Renal Function Deterioration in Cardiac Surgical Patients Predicts In-Hospital Mortality and Long-Term Survival
Abstract
Postoperative renal function deterioration is a serious complication after cardiac surgery with cardiopulmonary bypass and is associated with increased in-hospital mortality. However, the long-term prognosis of patients with postoperative renal deterioration is not fully determined yet. Therefore, both in-hospital mortality and long-term survival were studied in patients with postoperative renal function deterioration. Included were 843 patients who underwent cardiac surgery with cardiopulmonary bypass in 1991. Postoperative renal function deterioration (increase in serum creatinine in the first postoperative week of at least 25%) occurred in 145 (17.2%) patients. In these patients, in-hospital mortality was 14.5%, versus 1.1% in patients without renal function deterioration (P < 0.001). Multivariate analysis significantly associated in-hospital mortality with postoperative renal function deterioration, re-exploration, postoperative cerebral stroke, duration of operation, age, and diabetes. In patients who were discharged alive, during long-term follow-up (100 mo), mortality was significantly increased in the patients with renal function deterioration (n = 124) as compared with those without renal function deterioration (hazard ratio 1.83; 95% confidence interval 1.38 to 3.20). Also after adjustment for other independently associated factors, the risk for mortality in patients with postoperative renal function deterioration remained elevated (hazard ratio 1.63; 95% confidence interval 1.15 to 2.32). The elevated risk for long-term mortality was independent of whether renal function had recovered at discharge from hospital. It is concluded that postoperative renal function deterioration in cardiac surgical patients not only results in increased in-hospital mortality but also adversely affects long-term survival.
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Cites
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Preoperative Renal Risk Stratification
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Level of kidney function as a risk factor for cardiovascular outcomes in the elderly
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Acute renal failure: time for consensus
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Cited by
Acute Kidney Injury, Mortality, Length of Stay, and Costs in Hospitalized Patients
Chertow, G. M., Burdick, E., Honour, M., Bonventre, J. V., & Bates, D. W. (2005) · Journal of the American Society of Nephrology · doi:10.1681/asn.2004090740 · Cited by 3,408
Coca, S. G., Yusuf, B., Shlipak, M. G., Garg, A. X., & Parikh, C. R. (2009) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2008.11.034 · Cited by 1,161
Cause of Death in Patients with Reduced Kidney Function
Thompson, S., James, M., Wiebe, N., Hemmelgarn, B., Manns, B., Klarenbach, S., & Tonelli, M. (2015) · Journal of the American Society of Nephrology · doi:10.1681/asn.2014070714 · Cited by 658
Acute Kidney Injury Associates with Increased Long-Term Mortality
Lafrance, J.-P., & Miller, D. R. (2010) · Journal of the American Society of Nephrology · doi:10.1681/asn.2009060636 · Cited by 616
Urinary IL-18 is an early predictive biomarker of acute kidney injury after cardiac surgery
Parikh, C. R., Mishra, J., Thiessen-Philbrook, H., Dursun, B., Ma, Q., Kelly, C., Dent, C., Devarajan, P., & Edelstein, C. L. (2006) · Kidney International · doi:10.1038/sj.ki.5001527 · Cited by 608
Metadata
- Authors
- Loef, B. G., Epema, A. H., Smilde, T. D., Henning, R. H., Ebels, T., Navis, G., & Stegeman, C. A.
- Venue
- Journal of the American Society of Nephrology
- Published
- 2005-01
- Volume
- 16
- Issue
- 1
- Pages
- 195-200
- ISSN
- 1046-6673 (ISSN-L)
- OpenAlex
- W2154145185
- Cited by
- 466
- References
- 14
- FWCI
- 10.60
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Immediate Postoperative Renal Function Deterioration in Cardiac Surgical Patients Predicts In-Hospital Mortality and Long-Term Survival. https://app.cochat.ai/papers/10.1681/asn.2003100875
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- Loef, B. G., Epema, A. H., Smilde, T. D., Henning, R. H., Ebels, T., Navis, G., & Stegeman, C. A. (2005). Immediate Postoperative Renal Function Deterioration in Cardiac Surgical Patients Predicts In-Hospital Mortality and Long-Term Survival. Journal of the American Society of Nephrology. https://doi.org/10.1681/asn.2003100875
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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