The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Cause of Death in Patients with Reduced Kidney Function
Open accessAbstract
Information on common causes of death in people with CKD is limited. We hypothesized that, as eGFR declines, cardiovascular mortality and mortality from infection account for increasing proportions of deaths. We calculated eGFR using the CKD Epidemiology Collaboration equation for residents of Alberta, Canada who died between 2002 and 2009. We used multinomial logistic regression to estimate unadjusted and age- and sex-adjusted differences in the proportions of deaths from each cause according to the severity of CKD. Cause of death was classified as cardiovascular, infection, cancer, other, or not reported using International Classification of Diseases codes. Among 81,064 deaths, the most common cause was cancer (31.9%) followed by cardiovascular disease (30.2%). The most common cause of death for those with eGFR≥60 ml/min per 1.73 m(2) and no proteinuria was cancer (38.1%); the most common cause of death for those with eGFR<60 ml/min per 1.73 m(2) was cardiovascular disease. The unadjusted proportion of patients who died from cardiovascular disease increased as eGFR decreased (20.7%, 36.8%, 41.2%, and 43.7% of patients with eGFR≥60 [with proteinuria], 45-59.9, 30-44.9, and 15-29.9 ml/min per 1.73 m(2), respectively). The proportions of deaths from heart failure and valvular disease specifically increased with declining eGFR along with the proportions of deaths from infectious and other causes, whereas the proportion of deaths from cancer decreased. In conclusion, we found an inverse association between eGFR and specific causes of death, including specific types of cardiovascular disease, infection, and other causes, in this cohort.
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A New Equation to Estimate Glomerular Filtration Rate
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Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
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Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data
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International Statistical Classification of Diseases and Related Health Problems
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Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention
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Self-citationChronic Kidney Disease and Mortality Risk: A Systematic Review
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Self-citationThe contribution of chronic kidney disease to the global burden of major noncommunicable diseases
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Webster, A. C., Nagler, E. V., Morton, R. L., & Masson, P. (2017) · The Lancet · doi:10.1016/s0140-6736(16)32064-5 · Cited by 3,842
2024 ESC Guidelines for the management of chronic coronary syndromes
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Virani, S. S., Newby, L. K., Arnold, S. V., Bittner, V., Brewer, L. C., Demeter, S. H., Dixon, D. L., Fearon, W. F., Hess, B., Johnson, H. M., et al. (2023) · Circulation · doi:10.1161/cir.0000000000001168 · Cited by 1,598
FGF/FGFR signaling in health and disease
Xie, Y., Su, N., Yang, J., Tan, Q., Huang, S., Jin, M., Ni, Z., Zhang, B., Zhang, D., Luo, F., et al. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-00222-7 · Cited by 904
Metadata
- Authors
- Thompson, S., James, M., Wiebe, N., Hemmelgarn, B., Manns, B., Klarenbach, S., & Tonelli, M.
- Venue
- Journal of the American Society of Nephrology
- Published
- 2015-10
- Volume
- 26
- Issue
- 10
- Pages
- 2504-2511
- ISSN
- 1046-6673 (ISSN-L)
- OpenAlex
- W2096537254
- Cited by
- 658
- References
- 29
- FWCI
- 17.21
- Type
- journal article
- Language
- en
- Open access
- green
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- Thompson, S., James, M., Wiebe, N., Hemmelgarn, B., Manns, B., Klarenbach, S., & Tonelli, M. (2015). Cause of Death in Patients with Reduced Kidney Function. Journal of the American Society of Nephrology. https://doi.org/10.1681/asn.2014070714
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
