Cited by 215Ion Transport and Channel RegulationElectrolyte and hormonal disordersChemical and Physical Studies

The DOI matches its Crossref record; 188 of the 192 references it cites were found in a registry or an index.

Body Fluid Dynamics: Back to the Future

Open access
Bhave, Gautam, Neilson, Eric G.·2011·Journal of the American Society of Nephrology

Abstract

Pioneering investigations conducted over a half century ago on tonicity, transcapillary fluid exchange, and the distribution of water and solute serve as a foundation for understanding the physiology of body fluid spaces. With passage of time, however, some of these concepts have lost their connectivity to more contemporary information. Here we examine the physical forces determining the compartmentalization of body fluid and its movement across capillary and cell membrane barriers, drawing particular attention to the interstitium operating as a dynamic interface for water and solute distribution rather than as a static reservoir. Newer work now supports an evolving model of body fluid dynamics that integrates exchangeable Na(+) stores and transcapillary dynamics with advances in interstitial matrix biology.

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Crossref · 10.1681/asn.2011080865

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Research works printed but not linked: 1

  1. Bischoff, 1863, Einige Gewichts and Trockenbestimmungen der Organe des mensch lichen Korpers, Zeitsch fu rationelle Medizin, 3, 75

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Metadata

Authors
Bhave, G., & Neilson, E. G.
Affiliations
  • Vanderbilt University (US)
  • Northwestern University (US)
Corresponding author
  • Bhave, Gautam
  • Neilson, Eric G.
Venue
Journal of the American Society of Nephrology
Published
2011-12
Volume
22
Issue
12
Pages
2166-2181
ISSN
1046-6673 (ISSN-L)
OpenAlex
W2152290339
Cited by
215
References
192
Citations by year
2026: 9 · 2025: 15 · 2024: 49 · 2023: 15 · 2022: 21 · 2021: 27 · 2020: 18 · 2019: 18 · 2018: 13 · 2017: 3 · 2016: 4 · 2015: 6 · 2014: 8 · 2013: 6 · 2012: 2
FWCI
0.49
Type
journal article
Language
en
Open access
Locations
  • Journal of the American Society of Nephrology (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute of Diabetes and Digestive and Kidney Diseases (T32DK007569)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion Transport and Channel Regulation
  • Health Sciences › Medicine › Nephrology › Electrolyte and hormonal disorders
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Chemical and Physical Studies
Keywords
interstitial space, transcapillary fluid exchange, tonicity, capillary permeability, interstitial fluid
MeSH terms
Animals, Body Fluids, Forecasting, Humans, Hydrodynamics

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