The DOI matches its Crossref record; 188 of the 192 references it cites were found in a registry or an index.
Body Fluid Dynamics: Back to the Future
Open accessAbstract
Pioneering investigations conducted over a half century ago on tonicity, transcapillary fluid exchange, and the distribution of water and solute serve as a foundation for understanding the physiology of body fluid spaces. With passage of time, however, some of these concepts have lost their connectivity to more contemporary information. Here we examine the physical forces determining the compartmentalization of body fluid and its movement across capillary and cell membrane barriers, drawing particular attention to the interstitium operating as a dynamic interface for water and solute distribution rather than as a static reservoir. Newer work now supports an evolving model of body fluid dynamics that integrates exchangeable Na(+) stores and transcapillary dynamics with advances in interstitial matrix biology.
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“there appears to be equivalent losses of plasma volume between the sexes under similar exercise conditions [272,273] potentially representing sex differences in the compartmentalization of fluids.”
From International society of sports nutrition position stand: nutritional concerns of the female athlete (2023) · cites this paper as [273]
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Spasovski, G. B., Vanholder, R. C., Allolio, B., Annane, D., Ball, S., Bichet, D. G., Decaux, G., Fenske, W. K., Hoorn, E. J., Ichaï, C., et al. (2014) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfu040 · Cited by 602
The Role of Water Homeostasis in Muscle Function and Frailty: A Review
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Metadata
- Authors
- Bhave, G., & Neilson, E. G.
- Affiliations
- Vanderbilt University (US)
- Northwestern University (US)
- Corresponding author
- Bhave, Gautam
- Neilson, Eric G.
- Venue
- Journal of the American Society of Nephrology
- Published
- 2011-12
- Volume
- 22
- Issue
- 12
- Pages
- 2166-2181
- ISSN
- 1046-6673 (ISSN-L)
- PMC
- PMC4096826
- OpenAlex
- W2152290339
- Cited by
- 215
- References
- 192
- Citations by year
- 2026: 9 · 2025: 15 · 2024: 49 · 2023: 15 · 2022: 21 · 2021: 27 · 2020: 18 · 2019: 18 · 2018: 13 · 2017: 3 · 2016: 4 · 2015: 6 · 2014: 8 · 2013: 6 · 2012: 2
- FWCI
- 0.49
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of the American Society of Nephrology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (T32DK007569)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion Transport and Channel Regulation
- Health Sciences › Medicine › Nephrology › Electrolyte and hormonal disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Chemical and Physical Studies
- Keywords
- interstitial space, transcapillary fluid exchange, tonicity, capillary permeability, interstitial fluid
- MeSH terms
- Animals, Body Fluids, Forecasting, Humans, Hydrodynamics
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