Cited by 215Ion Transport and Channel RegulationElectrolyte and hormonal disordersChemical and Physical Studies

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Body Fluid Dynamics: Back to the Future

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Bhave, Gautam, Neilson, Eric G.·2011·Journal of the American Society of Nephrology

DOI 10.1681/asn.2011080865PMC PMC4096826

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Abstract

Pioneering investigations conducted over a half century ago on tonicity, transcapillary fluid exchange, and the distribution of water and solute serve as a foundation for understanding the physiology of body fluid spaces. With passage of time, however, some of these concepts have lost their connectivity to more contemporary information. Here we examine the physical forces determining the compartmentalization of body fluid and its movement across capillary and cell membrane barriers, drawing particular attention to the interstitium operating as a dynamic interface for water and solute distribution rather than as a static reservoir. Newer work now supports an evolving model of body fluid dynamics that integrates exchangeable Na(+) stores and transcapillary dynamics with advances in interstitial matrix biology.

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Thermodynamic analysis of the permeability of biological membranes to non-electrolytes
Kedem, O., & Katchalsky, A. (1958) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(58)90330-5 · Cited by 2,214
On the Absorption of Fluids from the Connective Tissue Spaces
Starling, E. H. (1896) · The Journal of Physiology · doi:10.1113/jphysiol.1896.sp000596 · Cited by 2,126
MATRIX PROTEOGLYCANS: From Molecular Design to Cellular Function
Iozzo, R. V. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.609 · Cited by 1,639
Total body water volumes for adult males and females estimated from simple anthropometric measurements
Watson, P. E., Watson, I. D., & Rd, B. (1980) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/33.1.27 · Cited by 1,477
The Structure and Function of the Endothelial Glycocalyx Layer
Weinbaum, S., Tarbell, J. M., & Damiano, E. R. (2007) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.9.060906.151959 · Cited by 1,204
Microvascular fluid exchange and the revised Starling principle
Levick, J. R., & Michel, C. C. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq062 · Cited by 1,183
Salt intakes around the world: implications for public health
Brown, I. J., Tzoulaki, I., Candeias, V., & Elliott, P. (2009) · International Journal of Epidemiology · doi:10.1093/ije/dyp139 · Cited by 1,173
Clinical Physiology of Acid-Base and Electrolyte Disorders
(1990) · Annals of Internal Medicine · doi:10.7326/0003-4819-113-2-176_8 · Cited by 1,152
A syndrome of renal sodium loss and hyponatremia probably resulting from inappropriate secretion of antidiuretic hormone
Schwartz, W. B., Bennett, W. A., Curelop, S., & Bartter, F. C. (1957) · The American Journal of Medicine · doi:10.1016/0002-9343(57)90224-3 · Cited by 1,151
A Triphasic Theory for the Swelling and Deformation Behaviors of Articular Cartilage
Lai, W. M., Hou, J., & Mow, V. C. (1991) · Journal of Biomechanical Engineering · doi:10.1115/1.2894880 · Cited by 1,131

Show all 192 references

Research works printed but not linked: 1

Bischoff, 1863, Einige Gewichts and Trockenbestimmungen der Organe des mensch lichen Korpers, Zeitsch fu rationelle Medizin, 3, 75

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Authors: Bhave, G., & Neilson, E. G.
Affiliations: Vanderbilt University (US)
Northwestern University (US)
Corresponding author: Bhave, Gautam
Neilson, Eric G.
ORCID: Bhave, Gautam
Neilson, Eric G.
Venue: Journal of the American Society of Nephrology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2011-12
Volume: 22
Issue: 12
Pages: 2166-2181
ISSN: 1046-6673 (ISSN-L)
DOI: 10.1681/asn.2011080865
PMC: PMC4096826
OpenAlex: W2152290339
Cited by: 215
References: 192
Citations by year: 2026: 9 · 2025: 15 · 2024: 49 · 2023: 15 · 2022: 21 · 2021: 27 · 2020: 18 · 2019: 18 · 2018: 13 · 2017: 3 · 2016: 4 · 2015: 6 · 2014: 8 · 2013: 6 · 2012: 2
FWCI: 0.49
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Journal of the American Society of Nephrology (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of Diabetes and Digestive and Kidney Diseases (T32DK007569)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion Transport and Channel Regulation
Health Sciences › Medicine › Nephrology › Electrolyte and hormonal disorders
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Chemical and Physical Studies
Keywords: interstitial space, transcapillary fluid exchange, tonicity, capillary permeability, interstitial fluid
MeSH terms: Animals, Body Fluids, Forecasting, Humans, Hydrodynamics

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