Salt intakes around the world: implications for public health
Abstract
BACKGROUND: High levels of dietary sodium (consumed as common salt, sodium chloride) are associated with raised blood pressure and adverse cardiovascular health. Despite this, public health efforts to reduce sodium consumption remain limited to a few countries. Comprehensive, contemporaneous sodium intake data from around the world are needed to inform national/international public health initiatives to reduce sodium consumption. METHODS: Use of standardized 24-h sodium excretion estimates for adults from the international INTERSALT (1985-87) and INTERMAP (1996-99) studies, and recent dietary and urinary sodium data from observational or interventional studies--identified by a comprehensive search of peer-reviewed and 'grey' literature--presented separately for adults and children. Review of methods for the estimation of sodium intake/excretion. Main food sources of sodium are presented for several Asian, European and Northern American countries, including previously unpublished INTERMAP data. RESULTS: Sodium intakes around the world are well in excess of physiological need (i.e. 10-20 mmol/day). Most adult populations have mean sodium intakes >100 mmol/day, and for many (particularly the Asian countries) mean intakes are >200 mmol/day. Possible exceptions include estimates from Cameroon, Ghana, Samoa, Spain, Taiwan, Tanzania, Uganda and Venezuela, though methodologies were sub-optimal and samples were not nationally representative. Sodium intakes were commonly >100 mmol/day in children over 5 years old, and increased with age. In European and Northern American countries, sodium intake is dominated by sodium added in manufactured foods ( approximately 75% of intake). Cereals and baked goods were the single largest contributor to dietary sodium intake in UK and US adults. In Japan and China, salt added at home (in cooking and at the table) and soy sauce were the largest sources. CONCLUSIONS: Unfavourably high sodium intakes remain prevalent around the world. Sources of dietary sodium vary largely worldwide. If policies for salt reduction at the population level are to be effective, policy development and implementation needs to target the main source of dietary sodium in the various populations.
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Most sodium in Asian countries comes from soy sauce or is added at home.
“In Asian countries, most sodium is from soy sauce or is added at home.158”
From Components of a Cardioprotective Diet: New Insights (2011) · cites this paper as [158]
Packaged, preprepared, or restaurant foods supply 75% of sodium intake in North America and Europe.
“In North America and Europe, 75% of sodium intake is derived from packaged, preprepared, or restaurant foods, with the rest being naturally occurring or added at home.158”
From Components of a Cardioprotective Diet: New Insights (2011) · cites this paper as [158]
In North America and Europe, most sodium (~75%) comes from packaged foods and restaurants, and little from home cooking or table salt; while in Asian countries, most sodium comes from soy sauce and salt added during cooking or at the table.
“In North America and Europe, most sodium (~75%) comes from packaged foods and restaurants, and little from home cooking or table salt; while in Asian countries, most sodium comes from soy sauce and salt added during cooking or at the table.302”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [302]
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Mozaffarian, D. (2016) · Circulation · doi:10.1161/circulationaha.115.018585 · Cited by 2,216 · see citing works
“sodium comes from soy sauce and salt added during cooking or at the table.(302) Nearly every country in the world exceeds the recommended mean national intake of 2000 mg/d.”
Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells
Kleinewietfeld, M., Manzel, A., Titze, J., Kvakan, H., Yosef, N., Linker, R. A., Muller, D. N., & Hafler, D. A. (2013) · Nature · doi:10.1038/nature11868 · Cited by 1,394 · see citing works
Cardiovascular Disease and Diabetes: Policies for Better Health and Quality of Care
OECD (2015) · OECD health policy studies · doi:10.1787/9789264233010-en · Cited by 1,377 · see citing works
Effect of lower sodium intake on health: systematic review and meta-analyses
Aburto, N. J., Ziolkovska, A., Hooper, L., Elliott, P., Cappuccio, F. P., & Meerpohl, J. J. (2013) · BMJ · doi:10.1136/bmj.f1326 · Cited by 1,242 · see citing works
Self-citationBiomarkers of Nutrition for Development—Folate Review
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“of the countries.(12) This has made it difficult to quantify global, regional or national levels of dietary sodium and the corresponding preventable disease burdens.”
BackgroundAburto, N., Hanson, S., Gutiérrez, H., Hooper, L., Elliott, P., & Cappuccio, F. P. (2013) · BMJ · doi:10.1136/bmj.f1378 · Cited by 956 · see citing works
Self-citationUrinary Sodium and Potassium Excretion, Mortality, and Cardiovascular Events
O'Donnell, M., Mente, A., Rangarajan, S., McQueen, M. J., Wang, X., Liu, L., Yan, H., Lee, S. F., Mony, P., Devanath, A., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1311889 · Cited by 886 · see citing works
Effect of salt substitution on cardiovascular events and death
Neal, B., Wu, Y., Feng, X., Zhang, R., Zhang, Y., Shi, J., Zhang, J., Tian, M., Huang, L., Li, Z., et al. (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2105675 · Cited by 742 · see citing works
Self-citationHypertension in developing countries
Ibrahim, M. M., & Damasceno, A. A. M. (2012) · The Lancet · doi:10.1016/s0140-6736(12)60861-7 · Cited by 738 · see citing works
The presence of microplastics in commercial salts from different countries
Karami, A., Golieskardi, A., Choo, C. K., Larat, V., Galloway, T. S., & Salamatinia, B. (2017) · Scientific Reports · doi:10.1038/srep46173 · Cited by 668 · see citing works
“Sodium is an essential element for the human body to maintain homeostasis and is mainly consumed as common salt (sodium chloride, NaCl) 18 .”
InfluentialReducing population salt intake worldwide: from evidence to implementation
He, F. J., & MacGregor, G. A. (2010) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2009.12.006 · Cited by 625 · see citing works
“Salt intake is commonly more than 6 g/d in children older than 5 years and increases with age.(1) Humans are genetically programmed to a salt intake of less than 0.”
BackgroundUrinary sodium and potassium excretion and risk of cardiovascular events
O'Donnell, M. J., Yusuf, S., Mente, A., Gao, P., Mann, J. F., Teo, K., McQueen, M., Sleight, P., Sharma, A. M., Dans, A., et al. (2011) · JAMA · doi:10.1001/jama.2011.1729 · Cited by 564 · see citing works
Anderson, C. A. M., Appel, L. J., Okuda, N., Brown, I., Chan, Q. M., Zhao, L., Ueshima, H., Kesteloot, H., Miura, K., Curb, J. D., et al. (2010) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2010.02.007 · Cited by 543 · see citing works
Self-citationComponents of a Cardioprotective Diet: New Insights
Mozaffarian, D., Appel, L. J., & Van Horn, L. (2011) · Circulation · doi:10.1161/circulationaha.110.968735 · Cited by 571 · see citing works
Assessment of iodine nutrition in populations: past, present, and future
Zimmermann, M. B., & Andersson, M. (2012) · Nutrition Reviews · doi:10.1111/j.1753-4887.2012.00528.x · Cited by 514 · see citing works
Arnold, M., Karim‐Kos, H. E., Coebergh, J. W. W., Byrnes, G. B., Anttila, A., Ferlay, J., Renehan, A. G., Forman, D., & Soerjomataram, I. (2013) · European Journal of Cancer · doi:10.1016/j.ejca.2013.09.002 · Cited by 513 · see citing works
“Diet Colorectum (+): high consumption of red and processed meat [49,50], low fibre intake [49,50] Colorectum ( ): diet high in fibre ( ), high intake of fresh fruits and vegetables ( ) [49,50] Stomach (++): high salt intake [36] Stomach ( ): high fruit and vegetable consumption ( ) [36], high vitamin C intake ( ) [36]…”
BackgroundAn Evolutionary Perspective on Food and Human Taste
Breslin, P. A. S. (2013) · Current Biology · doi:10.1016/j.cub.2013.04.010 · Cited by 512 · see citing works
“The similarity in salt intake cross-culturally suggests that humans consume this amount of salt because of biologically determined reasons [82].”
Lerner, A., & Matthias, T. (2015) · Autoimmunity Reviews · doi:10.1016/j.autrev.2015.01.009 · Cited by 475 · see citing works
“that in similar homemade meals [35].”
Prevention of stroke: a global perspective
Pandian, J. D., Gall, S., Kate, M. P., Silva, G. S., Akinyemi, R., Ovbiagele, B. I., Lavados, P. M., Gandhi, D. B. C., & Thrift, A. G. (2018) · The Lancet · doi:10.1016/s0140-6736(18)31269-8 · Cited by 458 · see citing works
Role of “Western Diet” in Inflammatory Autoimmune Diseases
Manzel, A., Müller, D. N., Hafler, D. A., Erdman, S. E., Linker, R. A., & Kleinewietfeld, M. (2013) · Current Allergy and Asthma Reports · doi:10.1007/s11882-013-0404-6 · Cited by 451 · see citing works
Sodium Reduction and Its Effect on Food Safety, Food Quality, and Human Health
Doyle, M. E., & Glass, K. A. (2009) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/j.1541-4337.2009.00096.x · Cited by 415 · see citing works
The Burden of Hypertension and Associated Risk for Cardiovascular Mortality in China
Lewington, S., Lacey, B., Clarke, R., Yu, C., Kong, X. L., Yang, L., Chen, Y., Bian, Z., Chen, J., Meng, J., et al. (2016) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2016.0190 · Cited by 395 · see citing works
Drinking Water Salinity and Maternal Health in Coastal Bangladesh: Implications of Climate Change
Khan, A. E., Ireson, A. M., Kovats, S. R., Mojumder, S. K., Khusru, A., Rahman, A., & Vineis, P. (2011) · Environmental Health Perspectives · doi:10.1289/ehp.1002804 · Cited by 378 · see citing works
“4 g/day (170 mmol/day), which is well above the WHO/FAO-recommended levels and above that of many other countries (Brown et al. 2009).”
InfluentialSodium-to-potassium ratio and blood pressure, hypertension, and related factors
Perez, V., & Chang, E. T. (2014) · Advances in Nutrition · doi:10.3945/an.114.006783 · Cited by 334 · see citing works
Contributions of risk factors and medical care to cardiovascular mortality trends
Ezzati, M., Obermeyer, Z., Tzoulaki, I., Mayosi, B. M., Elliott, P., & Leon, D. A. (2015) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2015.82 · Cited by 336 · see citing works
Self-citationDevelopment and evaluation of the Dutch Healthy Diet index 2015
Looman, M., Feskens, E. J. M., de Rijk, M. G., Meijboom, S., Biesbroek, S., Temme, E. H. M., de Vries, J. H. M., & Geelen, A. (2017) · Public Health Nutrition · doi:10.1017/s136898001700091x · Cited by 319 · see citing works
“Ideally, Na intake is estimated based on 24 h urinary-N, which is considered the gold standard for estimating Na intake((28)).”
BackgroundReducing Sodium in Foods: The Effect on Flavor
Liem, D. G., Miremadi, F., & Keast, R. (2011) · Nutrients · doi:10.3390/nu3060694 · Cited by 313 · see citing works
“The average US sodium intake is estimated to be 140–160 mmol Na/day (8.2–9.4 g NaCl/day) [13], United Kingdom 161 mmol Na/day (9.4 g NaCl/day) [16] and Asian countries higher than 206 mmol Na/day (12.0 g NaCl/day) [15].”
BackgroundInfluentialSalt reduction initiatives around the world
Webster, J. L., Dunford, E., Hawkes, C., & Neal, B. C. (2011) · Journal of Hypertension · doi:10.1097/hjh.0b013e328345ed83 · Cited by 314 · see citing works
Dietary salt intake and mortality in patients with type 2 diabetes
Ekinci, E. I., Clarke, S., Thomas, M. C., Moran, J. L., Cheong, K., MacIsaac, R. J., & Jerums, G. (2011) · Diabetes Care · doi:10.2337/dc10-1723 · Cited by 309 · see citing works
“For example, sodium intake is dominated by sodium added in manufactured foods in Western diets, (;75% of intake) (11).”
BackgroundResultInfluentialHypertension in the Developing World: Challenges and Opportunities
Mittal, B. V., & Singh, A. K. (2009) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2009.06.044 · Cited by 307 · see citing works
Grains – a major source of sustainable protein for health
Poutanen, K. S., Kårlund, A., Gómez-Gallego, C., Johansson, D. P., Scheers, N., Marklinder, I., Eriksen, A. K., Silventoinen, P., Nordlund, E., Sözer, N., et al. (2021) · Nutrition Reviews · doi:10.1093/nutrit/nuab084 · Cited by 318 · see citing works
Charchar, F. J., Prestes, P. R., Mills, C. E., Ching, S. M., Neupane, D., Marques, F. Z., Sharman, J. E., Vogt, L., Burrell, L. M., Коростовцева, Л. С., et al. (2023) · Journal of Hypertension · doi:10.1097/hjh.0000000000003563 · Cited by 352 · see citing works
“However, many community-based salt reduction programs resulted in decreased salt intake, International perspective About 80% of the salt intake in high-income countries table [111,129,139].”
Impact of Salt Intake on the Pathogenesis and Treatment of Hypertension
Rust, P., & Ekmekçioğlu, C. (2016) · Advances in experimental medicine and biology · doi:10.1007/5584_2016_147 · Cited by 292 · see citing works
Akter, T., Jhohura, F. T., Akter, F., Chowdhury, T. R., Mistry, S. K., Dey, D., Barua, M. K., Islam, M. A., & Rahman, M. (2016) · Journal of Health Population and Nutrition · doi:10.1186/s41043-016-0041-5 · Cited by 286 · see citing works
“Furthermore, reducing salt consumption from the global estimated levels of 9–12 g/day [42] to an acceptable limit of 5 g/day [43] would be predicted to reduce blood pressure and stroke/cardiovascular disease by 23 and 17 %, respectively [44].”
BackgroundSlagman, M. C. J., Waanders, F., Hemmelder, M. H., Woittiez, A.-J. J., Janssen, W. M. T., Heerspink, H. J. L., Navis, G. J., Laverman, G. D., & for the HONEST (HOlland NEphrology STudy) Group (2011) · BMJ · doi:10.1136/bmj.d4366 · Cited by 282 · see citing works
“day, but a substantial reduction in sodium intake to values in line with the guidelines for renal patients was nevertheless achieved.”
ResultBiomarkers of Nutrition for Development—Iodine Review
Rohner, F., Zimmermann, M. B., Jooste, P. L., Pandav, C. S., Caldwell, K. L., Raghavan, R., & Raiten, D. J. (2014) · Journal of Nutrition · doi:10.3945/jn.113.181974 · Cited by 281 · see citing works
Lachat, C. K., Otchere, S. A., Roberfroid, D., Abubakari, A., Seret, F. M. A., Milešević, J. P., Xuereb, G., Candeias, V., & Kolsteren, P. W. (2013) · PLoS Medicine · doi:10.1371/journal.pmed.1001465 · Cited by 280 · see citing works
“The mean salt intake in most LMICs exceeds the recommended maximum intake [7].”
BackgroundSelf-citationLanaspa, M. A., Kuwabara, M., Andrés-Hernando, A., Li, N., Cicerchi, C., Jensen, T., Orlicky, D. J., Roncal-Jiménez, C. A., Ishimoto, T., Nakagawa, T., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1713837115 · Cited by 282 · see citing works
“However, intake of salt is generally greater and can average >10 g/d in many populations (1).”
BackgroundSodium intake and its reduction by food reformulation in the European Union — A review
Kloss, L., Meyer, J. D., Graeve, L., & Vetter, W. (2015) · NFS Journal · doi:10.1016/j.nfs.2015.03.001 · Cited by 282 · see citing works
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“Another limitation was the lack of urine collection and analysis of 24-h urinary sodium excretion—the preferred method of obtaining sodium intake data in a population survey (73).”
MethodProcessed foods and the nutrition transition: evidence from<scp>A</scp>sia
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“High levels of dietary saturated and trans-fats (52), and sodium (59), are established risk factors for CVD.”
BackgroundKim, H., Hu, E. A., & Rebholz, C. M. (2019) · Public Health Nutrition · doi:10.1017/s1368980018003890 · Cited by 267 · see citing works
“largest sources of Na intake((51)), we expected to find higher Na intake in this group.”
BackgroundSodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention
Cook, N. R., Appel, L. J., & Whelton, P. K. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.07.745 · Cited by 228 · see citing works
“All urinary sodium and potassium measurements were expressed as milligrams per 24 h (15).”
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Worldwide Exposures to Cardiovascular Risk Factors and Associated Health Effects
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“With packaged or processed foods recognized as contributing about 75% of the daily salt intake in many high-income countries, and the increasing trend of processed food consumption in lower-middle–income and upper-middle–income countries (49, 50), these strategies might bring more positive changes in salt reduction in…”
BackgroundCost-effectiveness of interventions to reduce dietary salt intake
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“9 Many countries now recommend restricting daily sodium intake to 100 mmol (approximately 6 g of table salt) or less, but in a recent review of world salt levels, only seven out of the 25 countries reviewed met this goal.(13) A forum on salt, chaired by the WHO in 2006, stressed the need for immediate action and urged…”
BackgroundBurden of hypertension in China: A nationally representative survey of 174,621 adults
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“[27] The rapid increase in prevalence of hypertension in China may be explained by a number of prevailing lifestyle risk factors, such as high salt and more fat consuming in diet, more weight gaining (especially in men), less physical activities.[15, 16, 18, 28-30] Rapid urbanization and rural-to-urban migration in th…”
BackgroundBody Fluid Dynamics: Back to the Future
Bhave, G., & Neilson, E. G. (2011) · Journal of the American Society of Nephrology · doi:10.1681/asn.2011080865 · Cited by 215 · see citing works
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“In addition, the INTERSALT formula includes potassium intake, which may be appropriate in populations with similar dietary patterns, but not in international populations in whom sources of potassium and sodium, and their ratio, may vary [17].”
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“In Europe and North America, most sodium (’75%) comes from that added to foods due to commercial processing (10).”
BackgroundA Potential Link between Environmental Triggers and Autoimmunity
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“High levels of dietary sodium are associated with raised blood pressure and adverse cardiovascular health [75] and have been shown to affect the immune system [76].”
BackgroundInfluentialInnovations for healthier processed meats
Toldrá, F., & Reig, M. (2011) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2011.08.007 · Cited by 193 · see citing works
Salt and cardiovascular disease: insufficient evidence to recommend low sodium intake
O'Donnell, M. J., Mente, A., Alderman, M. H., Brady, A. J. B., Díaz, R., Gupta, R., López-Jaramillo, P. A., Luft, F. C., Lüscher, T. F., Mancia, G., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehaa586 · Cited by 195 · see citing works
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Salt-Responsive Metabolite, β-Hydroxybutyrate, Attenuates Hypertension
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“However, intake of salt is generally greater and can average >10 g/day in many populations (Brown et al., 2009).”
BackgroundBaudrand, R. F., Campino, C., Carvajal, C. A., Olivieri, O., Guidi, G. C., Faccini, G., Vöhringer, P. A., Jaime Cerda, L., Owen, G. I., Kalergis, A. M., et al. (2013) · Clinical Endocrinology · doi:10.1111/cen.12225 · Cited by 170 · see citing works
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Validity of predictive equations for 24-h urinary sodium excretion in adults aged 18–39 y
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“The majority of salt in Western diets comes from processed foods [31, 34] while in developing countries it comes from the salt that is added to food during food preparation [31].”
BackgroundMathenge, W. C., Foster, A., & Kuper, H. (2010) · BMC Public Health · doi:10.1186/1471-2458-10-569 · Cited by 155 · see citing works
“Kikuyus were significantly shorter yet heavier than Kalenjins among both men (166 cm vs 168 cm, 64 kg vs 60 kg) and women (156 cm vs 158 cm, 62 kg vs 58 kg) and consequently had higher BMIs.”
BackgroundInfluentialJaenke, R., Barzi, F., McMahon, E., Webster, J. L., & Brimblecombe, J. K. (2016) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2015.1118009 · Cited by 153 · see citing works
“to 75% of dietary sodium, predominantly via sodium chloride (hereafter, referred to as salt or NaCl), followed by a much lesser proportion from discretionary salt use or that which is naturally occurring (Brown et al., 2009).”
BackgroundRole of salt intake in prevention of cardiovascular disease: controversies and challenges
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Salt intakes in sub-Saharan Africa: a systematic review and meta-regression
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“Brown and colleagues [16] did not find any estimates for African children, while Powles and colleagues [15] did not include children in their systematic review.”
BackgroundResultInfluentialPlant-based diets: a review of the definitions and nutritional role in the adult diet
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“This is not unexpected as it is widely reported that sodium intake worldwide is well in excess of recommendations((96)).”
van Lee, L., Geelen, A., van Huysduynen, E. J. C. H., de Vries, J. H. M., Veer, P. V., & Feskens, E. J. M. (2012) · Nutrition Journal · doi:10.1186/1475-2891-11-49 · Cited by 151 · see citing works
“Preferably, sodium intake is measured in 24-hour urine samples, which is considered the standard for measuring sodium intake [37].”
BackgroundNutrition in cardiovascular disease: salt in hypertension and heart failure
He, F. J., Burnier, M., & MacGregor, G. A. (2011) · European Heart Journal · doi:10.1093/eurheartj/ehr194 · Cited by 150 · see citing works
“The current salt intake in many countries is between 9 and 12 g/day.(2) This large increase in salt intake is relatively recent in evolutionary terms.”
BackgroundEnvironmental factors in autoimmune diseases and their role in multiple sclerosis
Haase, S., Grohme, D. A., Erzler, M., Binsfeld, M., Haghikia, A., Müller, D. N., Linker, R. A., & Kleinewietfeld, M. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2311-1 · Cited by 152 · see citing works
“In particular, processed or so-called ‘fast foods’ may contain significantly more NaCl than homemade meals [145].”
BackgroundMohamed, S. F., Mutua, M. K., Wamai, R. G., Wekesah, F. M., Haregu, T., Juma, P. A., Nyanjau, L., Kyobutungi, C. K., & Ogola, E. N. (2018) · BMC Public Health · doi:10.1186/s12889-018-6052-y · Cited by 149 · see citing works
Use of Urine Biomarkers to Assess Sodium Intake: Challenges and Opportunities
Cogswell, M. E., Maalouf, J., Elliott, P., Loria, C. M., Patel, S., & Bowman, B. A. (2015) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-071714-034322 · Cited by 140 · see citing works
“The types of urine biomarkers (e.g., 24 h-urine sodium excretion) used in surveys and studies to assess sodium intake are often noted in systematic reviews of population sodium intake and the associations between sodium intake and health outcomes (2, 14, 24, 67, 120).”
Self-citationFactors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria
Boima, V., Ademola, A. D., Odusola, A. O., Agyekum, F., Nwafor, C. E., Cole, H. V. S., Salako, B. L., Ogedegbe, G. G., & Tayo, B. O. (2015) · International Journal of Hypertension · doi:10.1155/2015/205716 · Cited by 142 · see citing works
“Optimal blood pressure (BP) control with levels below 140/90mmHg is associated with significant reduction in cardiovascular complications such as stroke and coronary heart disease [12, 13].”
Effects of health labels on expected and actual taste perception of soup
Liem, D. G., Aydin, N. T., & Zandstra, E. H. (2012) · Food Quality and Preference · doi:10.1016/j.foodqual.2012.02.015 · Cited by 137 · see citing works
Antonini, S., Arias, M. A., Eichert, T., & Clemens, J. (2012) · Chemosphere · doi:10.1016/j.chemosphere.2012.07.026 · Cited by 137 · see citing works
“Higher values of urinary sodium secretion may be reflected by the dietary practice in Asian countries of using soy sauce as seasoning (Brown et al., 2009).”
MethodCampbell, N. R. C., He, F. J., Tan, M., Cappuccio, F. P., Neal, B. C., Woodward, M., Cogswell, M. E., McLean, R. M., Arcand, J., MacGregor, G. A., et al. (2019) · Journal of Clinical Hypertension · doi:10.1111/jch.13551 · Cited by 136 · see citing works
Tan, M., He, F. J., Wang, C., & MacGregor, G. A. (2019) · Journal of the American Heart Association · doi:10.1161/jaha.119.012923 · Cited by 139 · see citing works
“12,15 In contrast, potassium intake levels were less than half the recommended minimum intake for each age group.”
Anta, R. M. O., López-Sobaler, A. M., Ballesteros, J., Pérez‐Farinós, N., Rodríguez‐Rodríguez, E., Aparicio, A., Perea, J. M., & Andrés, P. (2010) · British Journal Of Nutrition · doi:10.1017/s000711451000423x · Cited by 135 · see citing works
Endothelial function is impaired after a high-salt meal in healthy subjects
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Salt reduction: Moving from consumer awareness to action
Zandstra, E. H., Lion, R., & Newson, R. S. (2015) · Food Quality and Preference · doi:10.1016/j.foodqual.2015.03.005 · Cited by 129 · see citing works
WASH—World Action on Salt and Health
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Salt intake and cardiovascular disease: why are the data inconsistent?
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“There are two main approaches to estimate sodium intake, namely measuring urinary excretion or dietary intake.(19) For either method, it is optimal to complete repeated measurements to capture ‘usual’ intake of sodium.”
BackgroundMethodThe role of sodium in modulating immune cell function
Wilck, N., Balogh, A., Markó, L., Bartolomaeus, H., & Müller, D. N. (2019) · Nature Reviews Nephrology · doi:10.1038/s41581-019-0167-y · Cited by 124 · see citing works
Current status of salt reduction in bread and bakery products – A review
Silow, C., Axel, C., Zannini, E., & Arendt, E. K. (2016) · Journal of Cereal Science · doi:10.1016/j.jcs.2016.10.010 · Cited by 120 · see citing works
Ghawi, S. K., Rowland, I. R., & Methven, L. (2014) · Appetite · doi:10.1016/j.appet.2014.05.029 · Cited by 118 · see citing works
Microplastics in Salt of Tuticorin, Southeast Coast of India
Sathish, N., Jeyasanta, K. I., & Patterson, J. (2020) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s00244-020-00731-0 · Cited by 115 · see citing works
Jia, Y. P., Niu, C.-T., Lu, Z., Zhang, X.-J., Chai, L., Shi, J., Xu, Z., & Li, Q. (2020) · Applied and Environmental Microbiology · doi:10.1128/aem.00306-20 · Cited by 121 · see citing works
“to increased risk of hypertension, cardiovascular mortality (3), and obesity (4), and so it”
BackgroundLand, M., Webster, J. L., Christoforou, A., Praveen, D., Jeffery, P., Chalmers, J. P., Smith, W. T., Woodward, M., Barzi, F., Nowson, C. A., et al. (2014) · BMJ Open · doi:10.1136/bmjopen-2013-003720 · Cited by 115 · see citing works
“17 With centrally managed salt reduction programmes projected to deliver large population health gains at very low cost, 18 – 20 the implementation of an effective salt reduction programme should be a priority for the government of Australia.”
BackgroundCampmans-Kuijpers, M. J. E., & Dijkstra, G. D. H. (2021) · Nutrients · doi:10.3390/nu13041067 · Cited by 115 · see citing works
“Surprisingly, countries like China with the highest salt intakes, have lower rates of IBD compared to the Western countries [238,239].”
BackgroundEstimativa de consumo de sódio pela população brasileira, 2008-2009
Sarno, F., Claro, R. M., Levy, R. B., Bandoni, D. H., & Monteiro, C. A. (2013) · Revista de Saúde Pública · doi:10.1590/s0034-8910.2013047004418 · Cited by 112 · see citing works
“575 Rev Saúde Pública 2013;47(3):571-8”
BackgroundInfluentialEvaluation of a screener to assess diet quality in the Netherlands
van Lee, L., Feskens, E. J. M., Meijboom, S., van Huysduynen, E. J. C. H., Veer, P. V., de Vries, J. H. M., & Geelen, A. (2015) · British Journal Of Nutrition · doi:10.1017/s0007114515004705 · Cited by 109 · see citing works
“Urinary Na level was measured using an ion-selective electrode from a Roche/Hitachi 917 analyser (Roche)((22)) at SHO in Velp, the Netherlands.”
MethodA salty‐congruent odor enhances saltiness: Functional magnetic resonance imaging study
Seo, H., Iannilli, E., Hummel, C., Okazaki, Y., Buschhüter, D., Gerber, J. C., Krammer, G. E., van Lengerich, B., & Hummel, T. R. (2011) · Human Brain Mapping · doi:10.1002/hbm.21414 · Cited by 112 · see citing works
“Nevertheless, the average amount of salt intake indeed exceeds the recommended daily intakes in children as well as in adults of worldwide population [Brown et al., 2009].”
BackgroundDietary Salt Intake and Risk of Gastric Cancer
D’Elia, L., Galletti, F., & Strazzullo, P. (2013) · Cancer treatment and research · doi:10.1007/978-3-642-38007-5_6 · Cited by 109 · see citing works
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The Science of Salt: Updating the evidence on global estimates of salt intake
Thout, S. R., Santos, J. A., McKenzie, B. L., Trieu, K., Johnson, C., McLean, R. M., Arcand, J., Campbell, N. R. C., & Webster, J. L. (2019) · Journal of Clinical Hypertension · doi:10.1111/jch.13546 · Cited by 108 · see citing works
Reducing salt intake to prevent hypertension and cardiovascular disease
He, F. J., Campbell, N. R. C., & MacGregor, G. A. (2012) · Revista Panamericana de Salud Pública · doi:10.1590/s1020-49892012001000008 · Cited by 110 · see citing works
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“Despite rigorous campaigns to reduce Na and increase K intake, a large gap remains between the recommended and actual intakes of both Na and K [18,19].”
BackgroundSalt in bread in Europe: potential benefits of reduction
Quı́lez, J., & Salas‐Salvadó, J. (2012) · Nutrition Reviews · doi:10.1111/j.1753-4887.2012.00540.x · Cited by 105 · see citing works
Low-salt diet increases insulin resistance in healthy subjects
Garg, R., Williams, G. H., Hurwitz, S., Brown, N. J., Hopkins, P. N., & Adler, G. K. (2010) · Metabolism · doi:10.1016/j.metabol.2010.09.005 · Cited by 108 · see citing works
“Our study is the largest study in healthy subjects, includes both men and women, was performed under carefully controlled conditions, and utilized a sodium content for the HS diet that is comparable to the average sodium intake in the US population [15].”
Method
- Authors
- Brown, I. J., Tzoulaki, I., Candeias, V., & Elliott, P.
- Affiliations
- Imperial College London (GB)
- World Health Organization (CH)
- Corresponding author
- Elliott, P.
- Venue
- International Journal of Epidemiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-04-07
- Volume
- 38
- Issue
- 3
- Pages
- 791-813
- ISSN
- 0300-5771 (ISSN-L)
- 1464-3685
- OpenAlex
- W2154301407
- Cited by
- 1,173
- References
- 157
- Citations by year
- 2026: 13 · 2025: 31 · 2024: 33 · 2023: 61 · 2022: 66 · 2021: 87 · 2020: 94 · 2019: 81 · 2018: 78 · 2017: 90 · 2016: 98 · 2015: 109 · 2014: 95 · 2013: 92 · 2012: 61
- FWCI
- 46.14
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- World Health Organization
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Sodium Intake and Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Keywords
- sodium intake, salt reduction, sodium excretion, INTERSALT, INTERMAP, sodium sources, processed foods, soy sauce, blood pressure, cardiovascular health, salt reduction policy, cross-national comparison
- MeSH terms
- Adolescent, Adult, Cardiovascular Diseases, Child, Child, Preschool, Cooking, Cross-Cultural Comparison, Diet, Feeding Behavior, Female, Health Promotion, Humans, Hypertension, Infant, Infant, Newborn, Health Knowledge, Attitudes, Practice, Male, Middle Aged, Global Health, Sodium Chloride, Dietary, Young Adult
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