The DOI matches its Crossref record; 107 of the 107 references it cites were found in a registry or an index.
Angiotensin-converting enzyme inhibitor fetopathy.
Abstract
Angiotensin-converting enzyme (ACE) inhibitors are widely used for controlling hypertension. Their use in women who are pregnant is not without risk to the fetus. We describe three infants exposed in utero to ACE inhibitors who had adverse outcomes. These cases, combined with other reports in the literature, suggest strongly that these drugs are fetotoxic. ACE inhibitor fetopathy is characterized by fetal hypotension, anuria-oligohydramnios, growth restriction, pulmonary hypoplasia, renal tubular dysplasia, and hypocalvaria. Although the true frequency of adverse fetal effects has yet to be determined, because of the debilitating and lethal nature of the fetal damage when it occurs, it is our recommendation that ACE inhibitors not be used in pregnancy, particularly in the second and third trimesters.
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Cites
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Cited by
Kobori, H., Nangaku, M., Navar, L. G., & Nishiyama, A. (2007) · Pharmacological Reviews · doi:10.1124/pr.59.3.3 · Cited by 1,237
Bushnell, C., McCullough, L. D., Awad, I. A., Chireau, M. V., Fedder, W. N., Furie, K. L., Howard, V. J., Lichtman, J. H., Lisabeth, L. D., Piña, I. L., et al. (2014) · Stroke · doi:10.1161/01.str.0000442009.06663.48 · Cited by 941
Angiotensin-Converting Enzyme Inhibitors
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Huynh, K., Bernardo, B. C., McMullen, J. R., & Ritchie, R. H. (2014) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2014.01.003 · Cited by 553
Bullo, M., Tschumi, S., Bucher, B. S., Bianchetti, M. G., & Simonetti, G. D. (2012) · Hypertension · doi:10.1161/hypertensionaha.112.196352 · Cited by 334
Metadata
- Authors
- Pryde, P. G., Sedman, A. B., Nugent, C. E., & Barr, M.
- Venue
- Journal of the American Society of Nephrology
- Published
- 1993-03
- Volume
- 3
- Issue
- 9
- Pages
- 1575-1582
- ISSN
- 1046-6673 (ISSN-L)
- OpenAlex
- W2156645886
- Cited by
- 332
- References
- 107
- FWCI
- 9.59
- Type
- journal article
- Language
- en
- Open access
- closed
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- Pryde, P. G., Sedman, A. B., Nugent, C. E., & Barr, M. (1993). Angiotensin-converting enzyme inhibitor fetopathy. Journal of the American Society of Nephrology. https://doi.org/10.1681/asn.v391575
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
