Intracellular, in vitro somatic membrane potential recordings from whole cell patch clamped rodent hippocampal CA1 neurons

Abstract

This data set contains the raw data files of current injection sweeps from somatic injections of the experimental cells (mouse and rat under standard “control” in vitro recording conditions) that were used to constrain the model cells of the model CA1 neural network published in: Marianne J. Bezaire, Ivan Raikov, Kelly Burk, Dhrumil Vyas, and Ivan Soltesz. Interneuronal mechanisms of hippocampal theta oscillations in full-scale models of the CA1 circuit. Under Review, 2016. Results from the experiments are described in: Sang-Hun Lee, Ivan Marchionni, Marianne Bezaire, Csaba Varga, Nathan Danielson, Matthew Lovett-Barron, Attila Losonczy, and Ivan Soltesz. Parvalbumin-positive basket cells differentiate among hippocampal pyramidal cells. Neuron, 82(5):1129–1144, 2014. doi: 10.1016/j.neuron.2014.03.034. Esther Krook-Magnuson, Lillian Luu, Sang-Hun Lee, Csaba Varga, and Ivan Soltesz. Ivy and neurogliaform interneurons are a major target of µ-opioid receptor modulation. The Journal of Neuroscience, 31(42):14861–14870, 2011. doi: 10.1523/JNEUROSCI.2269-11.2011. Sang-Hun Lee, Csaba Foldy, and Ivan Soltesz. Distinct endocannabinoid control of GABA release at perisomatic and dendritic synapses in the hippocampus. J. Neurosci., 30:7993–8000, 2010. doi: 10.1523/JNEUROSCI.6238-09.2010.