The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.
α-Amylase Inhibitors: A Review of Raw Material and Isolated Compounds from Plant Source
Open accessAbstract
ABSTRACT - Inhibition of α-amylase, enzyme that plays a role in digestion of starch and glycogen, is considered a strategy for the treatment of disorders in carbohydrate uptake, such as diabetes and obesity, as well as, dental caries and periodontal diseases. Plants are an important source of chemical constituents with potential for inhibition of α-amylase and can be used as therapeutic or functional food sources. A review about crude extracts and isolated compounds from plant source that have been tested for α-amylase inhibitory activity has been done. The analysis of the results shows a variety of crude extracts that present α-amylase inhibitory activity and some of them had relevant activity when compared with controls used in the studies. Amongst the phyto-constituents that have been investigated, flavonoids are one of them that demonstrated the highest inhibitory activities with the potential of inhibition related to number of hydroxyl groups in the molecule of the compound. Several phyto-constituents and plant species as α-amylase inhibitors are being reported in this article. Majority of studies have focused on the anti-amylase phenolic compounds. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.
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Cites
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Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects
Rahman, M. M., Rahaman, M. S., Islam, M. R., Rahman, F., Mithi, F. M., Alqahtani, T., Almikhlafi, M. A., Alghamdi, S. Q., Alruwaili, A. S., Hossain, M. S., et al. (2021) · Molecules · doi:10.3390/molecules27010233 · Cited by 852
Berberine in Cardiovascular and Metabolic Diseases: From Mechanisms to Therapeutics
Feng, X., Sureda, A., Jafari, S., Memariani, Z., Tewari, D., Annunziata, G., Barrea, L., Hassan, S. T. S., Šmejkal, K., Malaník, M., et al. (2019) · Theranostics · doi:10.7150/thno.30787 · Cited by 465
Oboh, G., Agunloye, O. M., Adefegha, S. A., Akinyemi, A. J., & Ademiluyi, A. O. (2015) · Journal of Basic and Clinical Physiology and Pharmacology · doi:10.1515/jbcpp-2013-0141 · Cited by 363
Antinutrients in Plant-based Foods: A Review
Popova, A., & Mihaylova, D. (2019) · The Open Biotechnology Journal · doi:10.2174/1874070701913010068 · Cited by 351
Podsędek, A., Majewska, I., Redzynia, M., Sosnowska, D., & Koziołkiewicz, M. (2014) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf5008264 · Cited by 266
Metadata
- Authors
- Sales, P. M., Souza, P. M., Simeoni, L. A., Magalhães, P. O., & Silveira, D.
- Venue
- Journal of Pharmacy & Pharmaceutical Sciences
- Publisher
- Frontiers Media SA
- Published
- 2012-02-10
- Volume
- 15
- Issue
- 1
- Pages
- 141
- ISSN
- 1482-1826 (ISSN-L)
- OpenAlex
- W1589514561
- Cited by
- 599
- References
- 56
- FWCI
- 17.26
- Type
- journal article
- Language
- en
- Open access
- gold
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