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Cited by 599

The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.

α-Amylase Inhibitors: A Review of Raw Material and Isolated Compounds from Plant Source

Open access
Sales, Paloma Michelle, Souza, Paula Monteiro, Simeoni, Luiz Alberto, Magalhães, Pérola Oliveira, Silveira, Damaris·2012·Journal of Pharmacy & Pharmaceutical Sciences

Abstract

ABSTRACT - Inhibition of α-amylase, enzyme that plays a role in digestion of starch and glycogen, is considered a strategy for the treatment of disorders in carbohydrate uptake, such as diabetes and obesity, as well as, dental caries and periodontal diseases. Plants are an important source of chemical constituents with potential for inhibition of α-amylase and can be used as therapeutic or functional food sources. A review about crude extracts and isolated compounds from plant source that have been tested for α-amylase inhibitory activity has been done. The analysis of the results shows a variety of crude extracts that present α-amylase inhibitory activity and some of them had relevant activity when compared with controls used in the studies. Amongst the phyto-constituents that have been investigated, flavonoids are one of them that demonstrated the highest inhibitory activities with the potential of inhibition related to number of hydroxyl groups in the molecule of the compound. Several phyto-constituents and plant species as α-amylase inhibitors are being reported in this article. Majority of studies have focused on the anti-amylase phenolic compounds. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.

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Crossref · 10.18433/j35s3k

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Metadata

Authors
Sales, P. M., Souza, P. M., Simeoni, L. A., Magalhães, P. O., & Silveira, D.
Venue
Journal of Pharmacy & Pharmaceutical Sciences
Published
2012-02-10
Volume
15
Issue
1
Pages
141
ISSN
1482-1826 (ISSN-L)
OpenAlex
W1589514561
Cited by
599
References
56
FWCI
17.26
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: α-Amylase Inhibitors: A Review of Raw Material and Isolated Compounds from Plant Source. https://app.cochat.ai/papers/10.18433/j35s3k
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Sales, P. M., Souza, P. M., Simeoni, L. A., Magalhães, P. O., & Silveira, D. (2012). α-Amylase Inhibitors: A Review of Raw Material and Isolated Compounds from Plant Source. Journal of Pharmacy & Pharmaceutical Sciences. https://doi.org/10.18433/j35s3k

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.