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Berberine-induced bioactive metabolites of the gut microbiota improve energy metabolism

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Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy

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Phenotypic Modulation of Vascular Smooth Muscle Cells Induced by Unsaturated Lysophosphatidic Acids

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Berberine exerts nephroprotective effect against cisplatin-induced kidney damage through inhibition of oxidative/nitrosative stress, inflammation, autophagy and apoptosis

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Effect of traditional Chinese medicine berberine on type 2 diabetes based on comprehensive metabonomics

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The Pathogenesis of Diabetes Mellitus by Oxidative Stress and Inflammation: Its Inhibition by Berberine

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Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway

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Effects and Action Mechanisms of Berberine and Rhizoma coptidis on Gut Microbes and Obesity in High-Fat Diet-Fed C57BL/6J Mice

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Effects and mechanisms of berberine in diabetes treatment

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Intestinal microbiota and type 2 diabetes: From mechanism insights to therapeutic perspective

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Reactive Oxygen Species Generation and Atherosclerosis

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Extracellular Signal-Regulated Kinase–Dependent Stabilization of Hepatic Low-Density Lipoprotein Receptor mRNA by Herbal Medicine Berberine

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Pharmacological effects of berberine and its derivatives: a patent update

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Neuroprotective effects of berberine on stroke models in vitro and in vivo

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S creening alpha‐glucosidase and alpha‐amylase inhibitors from natural compounds by molecular docking in silico

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The Effects of Berberine on Blood Lipids: A Systemic Review and Meta-Analysis of Randomized Controlled Trials

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Berberine reduces ischemia/reperfusion-induced myocardial apoptosis via activating AMPK and PI3K–Akt signaling in diabetic rats

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Curcumin by down-regulating NF-kB and elevating Nrf2, reduces brain edema and neurological dysfunction after cerebral I/R

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Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase

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Combination of simvastatin with berberine improves the lipid-lowering efficacy

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Berberine protects rat heart from ischemia/reperfusion injury via activating JAK2/STAT3 signaling and attenuating endoplasmic reticulum stress

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Atherosclerosis Is an Epigenetic Disease

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Berberine as a therapy for type 2 diabetes and its complications: From mechanism of action to clinical studies

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Inhibition of PCSK9 Transcription by Berberine Involves Down-regulation of Hepatic HNF1α Protein Expression through the Ubiquitin-Proteasome Degradation Pathway

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Berberine reduces methylation of the MTTP promoter and alleviates fatty liver induced by a high-fat diet in rats

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Comparison of anti-inflammatory effects of berberine, and its natural oxidative and reduced derivatives from Rhizoma Coptidis in vitro and in vivo

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A clinical study on the short-term effect of berberine in comparison to metformin on the metabolic characteristics of women with polycystic ovary syndrome

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Modulation of gut microbiota contributes to curcumin-mediated attenuation of hepatic steatosis in rats

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Perioperative beta-blockers for preventing surgery-related mortality and morbidity

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Segmental Aortic Stiffening Contributes to Experimental Abdominal Aortic Aneurysm Development

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Berberine alleviates cardiac ischemia/reperfusion injury by inhibiting excessive autophagy in cardiomyocytes

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Altered Mucus Glycosylation in Core 1 O-Glycan-Deficient Mice Affects Microbiota Composition and Intestinal Architecture

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Berberine attenuates hepatic steatosis and enhances energy expenditure in mice by inducing autophagy and fibroblast growth factor 21

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Kinetic difference of berberine between hippocampus and plasma in rat after intravenous administration of Coptidis rhizoma extract

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Activation of AMP-Activated Protein Kinase Is Required for Berberine-Induced Reduction of Atherosclerosis in Mice: The Role of Uncoupling Protein 2

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Berberine attenuates lipopolysaccharide-induced extracelluar matrix accumulation and inflammation in rat mesangial cells: Involvement of NF-κB signaling pathway

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Berberine attenuates ischemia–reperfusion injury through inhibiting HMGB1 release and NF-κB nuclear translocation

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Rhizoma Coptidis and Berberine as a Natural Drug to Combat Aging and Aging-Related Diseases via Anti-Oxidation and AMPK Activation

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Studies on preventive and curative effects of berberine on chemical-induced hepatotoxicity in rodents

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Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular events

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Modulating gut microbiota as an anti-diabetic mechanism of berberine

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Natural approaches in metabolic syndrome management

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Repeated administration of berberine inhibits cytochromes P450 in humans

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Lipid-lowering effect of berberine in human subjects and rats

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Berberine Modulates Gut Microbiota and Reduces Insulin Resistance via the TLR4 Signaling Pathway

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Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study

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Berberine attenuates bleomycin induced pulmonary toxicity and fibrosis via suppressing NF-κB dependant TGF-β activation: A biphasic experimental study

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Berberine alleviates insulin resistance by reducing peripheral branched-chain amino acids

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Cardiovascular effects of berberine in patients with severe congestive heart failure

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P-glycoprotein-mediated transport of berberine across Caco-2 cell monolayers

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Endothelial Function and Dysfunction: Impact of Metformin

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Berberine inhibits adipogenesis in high-fat diet-induced obesity mice

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Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials

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Modulation of glucagon-like peptide-1 release by berberine: In vivo and in vitro studies

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PPARs and the complex journey to obesity

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Berberine Attenuates Myocardial Ischemia/Reperfusion Injury by Reducing Oxidative Stress and Inflammation Response: Role of Silent Information Regulator 1

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Atheroprotective Effects and Molecular Targets of Tanshinones Derived From Herbal Medicine Danshen

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Metformin and berberine, two versatile drugs in treatment of common metabolic diseases

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Vasorelaxant and antiproliferative effects of berberine

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AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation

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Berberine improves pressure overload-induced cardiac hypertrophy and dysfunction through enhanced autophagy

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Berberine Attenuates Intestinal Mucosal Barrier Dysfunction in Type 2 Diabetic Rats

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Eulipidemic Effects of Berberine Administered Alone or in Combination with Other Natural Cholesterol-lowering Agents

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Integrative analysis of metabolome and gut microbiota in diet-induced hyperlipidemic rats treated with berberine compounds

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Effect of berberine administration on metabolic syndrome, insulin sensitivity, and insulin secretion

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Berberine mitigates cyclophosphamide-induced hepatotoxicity by modulating antioxidant status and inflammatory cytokines

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Effects of berberine on lipid profile in subjects with low cardiovascular risk

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Rhizoma Coptidis: A Potential Cardiovascular Protective Agent

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Berberine Ameliorates Hepatic Steatosis and Suppresses Liver and Adipose Tissue Inflammation in Mice with Diet-induced Obesity

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Berberine treatment reduces atherosclerosis by mediating gut microbiota in apoE-/- mice

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The antihypertensive and vasodilator effects of aqueous extract fromBerberis vulgaris fruit on hypertensive rats

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Neuroprotection of early and short-time applying berberine in the acute phase of cerebral ischemia: Up-regulated pAkt, pGSK and pCREB, down-regulated NF-κB expression, ameliorated BBB permeability

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Berberine improves endothelial function by reducing endothelial microparticles-mediated oxidative stress in humans

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Displacement of Bilirubin from Albumin by Berberine

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Type 1 diabetes, hyperglycaemia, and the heart

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Berberine inhibits PTP1B activity and mimics insulin action

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Berberine: Pathways to protect neurons

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Protective Effects of Berberine against Low-Density Lipoprotein (LDL) Oxidation and Oxidized LDL-Induced Cytotoxicity on Endothelial Cells

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Ameliorative effect of berberine on endothelial dysfunction in diabetic rats induced by high-fat diet and streptozotocin

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Berberine improves insulin resistance in cardiomyocytes via activation of 5′-adenosine monophosphate-activated protein kinase

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Berberine inhibits palmitate-induced NLRP3 inflammasome activation by triggering autophagy in macrophages: A new mechanism linking berberine to insulin resistance improvement

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Berberine Ameliorates MCAO Induced Cerebral Ischemia/Reperfusion Injury via Activation of the BDNF–TrkB–PI3K/Akt Signaling Pathway

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Berberine ameliorates inflammation in patients with acute coronary syndrome following percutaneous coronary intervention

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Familial Abdominal Aortic Aneurysm: a Systematic Review of a Genetic Background

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Poly(ADP‐ribose) Polymerase 1 (PARP1) in Atherosclerosis: From Molecular Mechanisms to Therapeutic Implications

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Targeting LOX‐1 in atherosclerosis and vasculopathy: current knowledge and future perspectives

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Palmatine from Coptidis rhizoma reduces ischemia–reperfusion-mediated acute myocardial injury in the rat

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Berberine Promotes Glucose Consumption Independently of AMP-Activated Protein Kinase Activation

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Lipid profiling of the therapeutic effects of berberine in patients with nonalcoholic fatty liver disease

Chang, X., Wang, Z., Zhang, J., Yan, H., Bian, H., Xia, M., Lin, H., Jiang, J., & Gao, X. (2016) · Journal of Translational Medicine · doi:10.1186/s12967-016-0982-x · Cited by 96 · see citing works

The effects of Forsythia suspensa extract and berberine on growth performance, immunity, antioxidant activities, and intestinal microbiota in broilers under high stocking density

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Protective effect of berberine against myocardial ischemia reperfusion injury: role of Notch1/Hes1-PTEN/Akt signaling

Yu, L., Li, F., Zhao, G., Yang, Y., Jin, Z., Zhai, M., Yu, W., Zhao, L., Chen, W., Duan, W., et al. (2015) · APOPTOSIS · doi:10.1007/s10495-015-1122-4 · Cited by 94 · see citing works

Cardiovascular and metabolic effects of Berberine

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Berberine-sonodynamic therapy induces autophagy and lipid unloading in macrophage

Kou, J., Li, Y., Zhong, Z., Jiang, Y., Li, X. S., Han, X. B., Liu, Z. N., Tian, Y., & Yang, L. M. (2017) · Cell Death and Disease · doi:10.1038/cddis.2016.354 · Cited by 94 · see citing works

Inflammation and atherosclerosis: Cardiovascular evaluation in patients with autoimmune diseases

Escarcega, R. O., Lipinski, M. J., García‐Carrasco, M., Pinto, C. M., Gálvez-Romero, J. L., & Cervera, R. (2018) · Autoimmunity Reviews · doi:10.1016/j.autrev.2018.01.021 · Cited by 93 · see citing works

Berberine improves glucogenesis and lipid metabolism in nonalcoholic fatty liver disease

Zhao, L., Cang, Z., Sun, H., Nie, X., Wang, N., & Lu, Y. (2017) · BMC Endocrine Disorders · doi:10.1186/s12902-017-0165-7 · Cited by 92 · see citing works

Pharmacologic therapy to induce weight loss in women who have obesity/overweight with polycystic ovary syndrome: a systematic review and network meta‐analysis

Wang, F., Wu, Y. T., Zhu, Y. ‐., Ding, T., Batterham, R. L., Qu, F., & Hardiman, P. J. (2018) · Obesity Reviews · doi:10.1111/obr.12720 · Cited by 92 · see citing works

Berberine improves endothelial function by inhibiting endoplasmic reticulum stress in the carotid arteries of spontaneously hypertensive rats

Liu, L., Liu, J., Huang, Z., Yu, X., Zhang, X., Dou, D., & Huang, Y. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.02.028 · Cited by 90 · see citing works

Modulation of Microbiota-Gut-Brain Axis by Berberine Resulting in Improved Metabolic Status in High-Fat Diet-Fed Rats

Sun, H., Wang, N., Cang, Z., Zhu, C., Zhao, L., Nie, X., Cheng, J., Xia, F., Zhai, H., & Lu, Y. (2016) · Obesity Facts · doi:10.1159/000449507 · Cited by 90 · see citing works

Perioperative beta-blockers for preventing surgery-related mortality and morbidity

Blessberger, H., Kammler, J., Domanovits, H., Schlager, O., Wildner, B., Azar, D., Schillinger, M., Wiesbauer, F., & Steinwender, C. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004476.pub3 · Cited by 90 · see citing works

Impact of sodium glucose cotransporter 2 (SGLT2) inhibitors on atherosclerosis: From pharmacology to pre-clinical and clinical therapeutics

Liu, Z., Ma, X., Ilyas, I., Zheng, X., Luo, S., Little, P. J., Kamato, D., Sahebkar, A., Wu, W., Weng, J., et al. (2021) · Theranostics · doi:10.7150/thno.54498 · Cited by 155 · see citing works

The Effect of Berberine on Metabolic Profiles in Type 2 Diabetic Patients: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Guo, J., Chen, H., Zhang, X., Lou, W., Zhang, P., Qiu, Y., Zhang, C., Wang, Y., & Liu, W. J. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/2074610 · Cited by 110 · see citing works

Berberine Reduces Aβ42 Deposition and Tau Hyperphosphorylation via Ameliorating Endoplasmic Reticulum Stress

Wu, Y., Chen, Q., Wen, B., Wu, N., He, B., & Chen, J. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.640758 · Cited by 54 · see citing works

Characterization and Pharmacokinetic Assessment of a New Berberine Formulation with Enhanced Absorption In Vitro and in Human Volunteers

Solnier, J., Zhang, Y., Kuo, Y., Du, M., Roh, K., Gahler, R., Wood, S., & Chang, C. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15112567 · Cited by 47 · see citing works

The effects of berberine supplementation on cardiovascular risk factors in adults: a systematic review and dose-response meta-analysis

Zamani, M., Zarei, M., Nikbaf-Shandiz, M., Hosseini, S., Shiraseb, F., & Asbaghi, O. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1013055 · Cited by 28 · see citing works

Supplemental Berberine in a High-Fat Diet Reduces Adiposity and Cardiac Dysfunction in Offspring of Mouse Dams with Gestational Diabetes Mellitus

Cole, L. K., Zhang, M., Chen, L., Sparagna, G. C., Vandel, M., Xiang, B., Dolinsky, V. W., & Hatch, G. M. (2021) · The Journal of Nutrition · doi:10.1093/jn/nxaa408 · Cited by 18 · see citing works

Sex‐Dependent Effects of <scp>CYP2D6</scp> on the Pharmacokinetics of Berberine in Humans

Blöcher, J. A., Meyer‐Tönnies, M. J., Morof, F., Rönnpagel, V., Bethmann, J., Vollmer, M., Engeli, S., & Tzvetkov, M. V. (2025) · Clinical Pharmacology &amp; Therapeutics · doi:10.1002/cpt.3454 · Cited by 16 · see citing works

DETERMINING QUALITY REQUIREMENTS AT THE UNIVERSITIES TO IMPROVE THE QUALITY OF EDUCATION

Mustafa, N. H., Kelesbayev, D., & Alibekova, Z. D. (2018) · The Journal of Economic Research & Business Administration · doi:10.26577/be-2018-2-2141

Susquehanna Chorale Spring Concert "Roots and Wings"

Hawkins, D. (2017)

Genentech taps Affimed’s antibodies

Cross, R. (2018) · C&EN Global Enterprise · doi:10.1021/cen-09635-buscon15

Berberine Contents as a Quality Marker in Medicinal Plants and Amounts of Berberine Passing into Serum

Aydın, S. C., Kalaycıoğlu, Z., & Erim, F. B. (2023) · Current Traditional Medicine · doi:10.2174/2215083810666230519115233 · Cited by 1 · see citing works

Berberine through PPAR- γ/HO-1 Pathway Regulates Macrophage PolarizationPreprint

li, Y., Shang, S., Wang, J., Yu, L., Wang, T., & Chen, Y. (2023) · Research Square · doi:10.21203/rs.3.rs-3187686/v1