Effect of Antioxidants on the H2O2-Induced Premature Senescence of Human Fibroblasts
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and suggest that the small protective action of antioxidants is due to their effects on mitochondria.
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Pieńkowska et al. highlighted that p-CA is unable to counteract premature senescence of human fibroblasts.
“However, although some works have demonstrated the antioxidant property of p-CA, Pieńkowska et al. highlighted that this acid is unable to counteract the premature senescence of human fibroblasts [387].”
From The Role of Antioxidants in the Interplay between Oxidative Stress and Senescence (2022) · cites this paper as [387]
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- Authors
- Pieńkowska, N., Bartosz, G., Pichla, M., Grzesik-Pietrasiewicz, M., Gruchala, M., & Sadowska-Bartosz, I.
- Affiliations
- University of Rzeszów (PL)
- University of Łódź (PL)
- Department of Analytical Biochemistry, Institute of Food Technology and Nutrition, College of Natural Sciences, Rzeszow University, Rzeszow, Poland
- Cytometry Lab, Department of Molecular Biophysics, Faculty of Biology and Environmental Protection University of Lodz, Lodz, Poland
- Venue
- Aging
- Publisher
- Impact Journals, LLC
- Published
- 2020-01-21
- Volume
- 12
- Issue
- 2
- Pages
- 1910-1927
- ISSN
- 1945-4589 (ISSN-L)
- PMC
- PMC7053616
- OpenAlex
- W3002469543
- Cited by
- 42
- References
- 32
- Citations by year
- 2026: 11 · 2025: 11 · 2024: 4 · 2023: 8 · 2022: 4 · 2021: 2 · 2020: 2
- FWCI
- 2.41
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- cc-by
- Locations
- Aging (publishedVersion)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- Narodowym Centrum Nauki
- Uniwersytet Rzeszowski
- Topics
- Health Sciences › Medicine › Physiology › Telomeres, Telomerase, and Senescence
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
- Keywords
- antioxidants, hydrogen peroxide, premature senescence, human fibroblasts, cellular aging, mitochondria, oxidative stress
- MeSH terms
- Antioxidants, beta-Galactosidase, Cell Line, Cell Survival, Cells, Cultured, Dose-Response Relationship, Drug, Fibroblasts, Glutathione, Humans, Hydrogen Peroxide, Mitochondria, Cellular Senescence, Apoptosis, Reactive Oxygen Species, Oxidative Stress, Membrane Potential, Mitochondrial
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