Cited by 534Meta-analysis and systematic reviewsStatistical Methods in Clinical TrialsData Analysis with R

netmeta : An R Package for Network Meta-Analysis Using Frequentist Methods

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Balduzzi, Sara, Rücker, Gerta, Nikolakopoulou, Adriani, Papakonstantinou, Theodoros, Salanti, Georgia, Efthimiou, Orestis, Schwarzer, Guido·2023·Journal of Statistical Software

Abstract

Network meta-analysis compares different interventions for the same condition, by combining direct and indirect evidence derived from all eligible studies. Network metaanalysis has been increasingly used by applied scientists and it is a major research topic for methodologists. This article describes the R package netmeta, which adopts frequentist methods to fit network meta-analysis models. We provide a roadmap to perform network meta-analysis, along with an overview of the main functions of the package. We present three worked examples considering different types of outcomes and different data formats to facilitate researchers aiming to conduct network meta-analysis with netmeta.

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Crossref · 10.18637/jss.v106.i02

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Authors
Balduzzi, S., Rücker, G., Nikolakopoulou, A., Papakonstantinou, T., Salanti, G., Efthimiou, O., & Schwarzer, G.
Affiliations
  • University of Freiburg (DE)
  • University of Bern (CH)
Venue
Journal of Statistical Software
Published
2023
Volume
106
Issue
2
ISSN
1548-7660 (ISSN-L)
OpenAlex
W4327640222
Cited by
532
References
67
Citations by year
2026: 221 · 2025: 176 · 2024: 108 · 2023: 27
FWCI
98.70
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Journal of Statistical Software (publishedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • National Science Foundation
  • Deutsche Forschungsgemeinschaft
  • Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (186723, 179158, 180083)
Topics
  • Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
  • Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
  • Physical Sciences › Computer Science › Artificial Intelligence › Data Analysis with R
Keywords
network meta-analysis, frequentist methods, direct and indirect evidence, intervention comparison, statistical software

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