Med-HALT: Medical Domain Hallucination Test for Large Language Models
Open accessAbstract
This research paper focuses on the challenges posed by hallucinations in large language models (LLMs), particularly in the context of the medical domain.Hallucination, wherein these models generate plausible yet unverified or incorrect information, can have serious consequences in healthcare applications.We propose a new benchmark and dataset, Med-HALT (Medical Domain Hallucination Test), designed specifically to evaluate and reduce hallucinations.Med-HALT provides a diverse multinational dataset derived from medical examinations across various countries and includes multiple innovative testing modalities.Med-HALT includes two categories of tests reasoning and memory-based hallucination tests, designed to assess LLMs' problem-solving and information retrieval abilities.Our study evaluated leading LLMs, including Text Davinci, GPT-3.5, LlaMa-2, MPT, and Falcon, revealing significant differences in their performance.The paper provides detailed insights into the dataset, promoting transparency and reproducibility.Through this work, we aim to contribute to the development of safer and more reliable language models in healthcare.Our benchmark can be found at med- halt.github.ioAIIMS PG (India) NEET PG (India) Exámenes médica (Spain) TWMLE (Taiwan) USMILE (U.S)
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Projecting to a large benchmark scenario (Med-HALT; 59,254 items), the cost of a full-length evaluation would be on the order of $1475 under stated pricing assumptions, whereas CAT-based evaluation would be under $5.
“Using empirically observed testing characteristics (e.g., an average of 37 items per administration and per-item token usage) and projecting them to a large benchmark scenario (Med-HALT; 59,254 items10), we estimate that the cost of a full-length evaluation would be on the order of $1475 under the stated pricing assumptions, whereas the CAT-based evaluation would be under $5.”
From Leveraging computerized adaptive testing for cost-effective evaluation of large language models in medical benchmarking (2026) · cites this paper as [10]
Section 2, “Datasets Statistics” (page unavailable), identifies Med-HALT as a large benchmark and reports 18,866 samples per reasoning-hallucination task plus a separate PubMed portion. It does not give the cited figure of 59,254 items. The $1,475 and under-$5 costs are explicitly the citing authors’ estimates, not claims attributed to Med-HALT. (LLM, conf=0.83)
Experimental — accuracy not yet measuredSome benchmarks incorporate custom metrics to capture trust facets.
“To capture trust facets, some benchmarks incorporate custom metrics: e.g., Med-HALT's false confidence rate (Pal et al., 2023), or MedSafety-Bench's safety score (Han et al., 2024a).”
From Trustworthy Medical Question Answering: An Evaluation-Centric Survey (2025) · cites this paper as Pal et al., 2023
The False Confidence Test section describes a Med-HALT test of whether models answer with unnecessary certainty. But the paper calls it a test, not a “false confidence rate”; its Evaluation matrices section reports accuracy and pointwise score rather than a metric by that name. No page number is available in our copy. (LLM, conf=0.86)
Experimental — accuracy not yet measuredMed-HALT incorporates a false confidence rate metric.
“To capture trust facets, some benchmarks incorporate custom metrics: e.g., Med-HALT's false confidence rate (Pal et al., 2023), or MedSafety-Bench's safety score (Han et al., 2024a).”
From Trustworthy Medical Question Answering: An Evaluation-Centric Survey (2025) · cites this paper as Pal et al., 2023
The False Confidence Test (FCT) section describes a Med-HALT test for answers given with unnecessary certainty. But the Evaluation matrices section names accuracy and pointwise score as metrics, not a “false confidence rate”; the cited paper supports a false-confidence test, not the specific metric claimed. The indexed passages provide section labels but no page numbers. (LLM, conf=0.86)
Experimental — accuracy not yet measuredAdversarial benchmarks like Med-HALT and targeted false-confidence probes stress-test models with challenging prompts designed to induce fabrications, thereby quantifying a model's propensity to hallucinate under duress.
“Adversarial benchmarks like Med-HALT (Pal et al., 2023) and targeted”
From Trustworthy Medical Question Answering: An Evaluation-Centric Survey (2025) · cites this paper as Pal et al., 2023
These frameworks typically focus on narrow clinical scenarios (1-28 datasets), rely on limited data sources or synthetic data, and assess primarily accuracy without comprehensive taxonomy validation or deployment considerations.
“However, these frameworks typically focus on narrow clinical scenarios (1–28 datasets), rely on limited data sources or synthetic data, and assess primarily accuracy without comprehensive taxonomy validation or deployment considerations.”
From Holistic evaluation of large language models for medical tasks with MedHELM (2026) · cites this paper as [24]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
PyTorch: An Imperative Style, High-Performance Deep Learning Library
Paszke, A., Gross, S., Massa, F., Lerer, A., Bradbury, J., Chanan, G., Killeen, T., Lin, Z., Gimelshein, N., Antiga, L., et al. (2019) · arXiv · doi:10.48550/arxiv.1912.01703 · Cited by 31,473 · see citing works
Language Models are Few-Shot Learners
Brown, T. B., Mann, B., Ryder, N., Subbiah, M., Kaplan, J., Dhariwal, P., Neelakantan, A., Shyam, P., Sastry, G., Askell, A., et al. (2020) · arXiv · doi:10.48550/arxiv.2005.14165 · Cited by 23,372 · see citing works
Survey of Hallucination in Natural Language Generation
Ji, Z., Lee, N., Frieske, R., Yu, T., Su, D., Xu, Y., Ishii, E., Bang, Y. J., Madotto, A., & Fung, P. (2023) · ACM Computing Surveys · doi:10.1145/3571730 · Cited by 5,025 · see citing works
Large Language Models Encode Clinical Knowledge
Singhal, K., Azizi, S., Tu, T., Mahdavi, S. S., Wei, J., Chung, H. W., Scales, N., Tanwani, A., Cole-Lewis, H., Pfohl, S., et al. (2022) · arXiv · doi:10.48550/arxiv.2212.13138 · Cited by 4,083 · see citing works
HuggingFace's Transformers: State-of-the-art Natural Language Processing
Wolf, T., Debut, L., Sanh, V., Chaumond, J., Delangue, C., Moi, A., Cistac, P., Rault, T., Louf, R., Funtowicz, M., et al. (2019) · arXiv · doi:10.48550/arxiv.1910.03771 · Cited by 3,347 · see citing works
The Curious Case of Neural Text Degeneration
Holtzman, A., Buys, J., Du, L., Forbes, M., & Choi, Y. (2019) · arXiv · doi:10.48550/arxiv.1904.09751 · Cited by 1,304 · see citing works
Finetuned Language Models Are Zero-Shot Learners
Wei, J., Bosma, M., Zhao, V. Y., Guu, K., Yu, A. W., Lester, B., Du, N., Dai, A. M., & Le, Q. V. (2021) · arXiv · doi:10.48550/arxiv.2109.01652 · Cited by 1,101 · see citing works
Jin, D., Pan, E., Oufattole, N., Weng, W.-H., Fang, H., & Szolovits, P. (2021) · Applied Sciences · doi:10.3390/app11146421 · Cited by 718 · see citing works
Training a Helpful and Harmless Assistant with Reinforcement Learning from Human Feedback
Bai, Y., Jones, A., Ndousse, K., Askell, A., Chen, A., DasSarma, N., Drain, D., Fort, S., Ganguli, D., Henighan, T., et al. (2022) · arXiv · doi:10.48550/arxiv.2204.05862 · Cited by 442 · see citing works
HaluEval: A Large-Scale Hallucination Evaluation Benchmark for Large Language Models
Li, J., Cheng, X., Zhao, X., Nie, J.-Y., & Wen, J.-R. (2023) · Proceedings of the 2023 Conference on Empirical Methods in Natural Language Processing · doi:10.18653/v1/2023.emnlp-main.397 · Cited by 343 · see citing works
HaluEval: A Large-Scale Hallucination Evaluation Benchmark for Large Language Models
Li, J., Cheng, X., Zhao, W. X., Nie, J.-Y., & Wen, J.-R. (2023) · arXiv · doi:10.48550/arxiv.2305.11747 · Cited by 340 · see citing works
Towards Expert-Level Medical Question Answering with Large Language Models
Singhal, K., Tu, T., Gottweis, J., Sayres, R., Wulczyn, E., Hou, L., Clark, K., Pfohl, S., Cole-Lewis, H., Neal, D., et al. (2023) · arXiv · doi:10.48550/arxiv.2305.09617 · Cited by 338 · see citing works
Bang, Y., Cahyawijaya, S., Lee, N., Dai, W., Su, D., Wilie, B., Lovenia, H., Ji, Z., Yu, T., Chung, W., et al. (2023) · arXiv · doi:10.48550/arxiv.2302.04023 · Cited by 337 · see citing works
Retrieval Augmentation Reduces Hallucination in ConversationPreprint
Shuster, K., Poff, S., Chen, M., Kiela, D., & Weston, J. (2021) · arXiv (Cornell University) · doi:10.48550/arxiv.2104.07567 · Cited by 172 · see citing works
Penedo, G., Malartic, Q., Hesslow, D., Cojocaru, R., Cappelli, A., Alobeidli, H., Pannier, B., Almazrouei, E., & Launay, J. (2023) · arXiv · doi:10.48550/arxiv.2306.01116 · Cited by 164 · see citing works
MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training DataPreprint
Han, T., Adams, L. C., Papaioannou, J.-M., Grundmann, P., Oberhauser, T., Figueroa, A., Löser, A., Truhn, D., & Bressem, K. K. (2023) · arXiv (Cornell University) · doi:10.48550/arxiv.2304.08247 · Cited by 117 · see citing works
A Token-level Reference-free Hallucination Detection Benchmark for Free-form Text Generation
Liu, T., Zhang, Y., Brockett, C., Mao, Y., Sui, Z., Chen, W., & Dolan, B. (2021) · arXiv · doi:10.48550/arxiv.2104.08704 · Cited by 12 · see citing works
HEAD-QA: A Healthcare Dataset for Complex ReasoningPreprint
Vilares, D., & Gómez‐Rodríguez, C. (2019) · arXiv (Cornell University) · doi:10.48550/arxiv.1906.04701 · Cited by 7 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Ankit Pal, Logesh Kumar Umapathi, and Malaikannan Sankarasubbu. 2022. Medmcqa: A large-scale multi- subject multi-choice dataset for medical domain ques- tion answering. In Proceedings of the Conference on Health, Inference, and Learning, volume 174 of Proceedings of Machine Learning Research, pages 248-260. PMLR.
Cited by
Sorted by citations
A framework to assess clinical safety and hallucination rates of LLMs for medical text summarisation
Asgari, E., Montaña-Brown, N., Dubois, M., Khalil, S., Balloch, J., Yeung, J. A., & Pimenta, D. (2025) · npj Digital Medicine · doi:10.1038/s41746-025-01670-7 · Cited by 423 · see citing works
A Survey of GPT-3 Family Large Language Models Including ChatGPT and GPT-4
Kalyan, K. S. (2024) · Natural Language Processing Journal · doi:10.1016/j.nlp.2023.100048 · Cited by 335 · see citing works
Retrieval augmented generation for large language models in healthcare: A systematic review
Amugongo, L. M., Mascheroni, P., Brooks, S., Doering, S., & Seidel, J. (2025) · PLOS Digital Health · doi:10.1371/journal.pdig.0000877 · Cited by 267 · see citing works
History, development, and principles of large language models: an introductory survey
Wang, Z., Chu, Z., Doan, T. V., Ni, S., Yang, M., & Zhang, W. (2025) · AI and Ethics · doi:10.1007/s43681-024-00583-7 · Cited by 109 · see citing works
Retrieval-Augmented Generation (RAG)
Klesel, M., & Wittmann, H. F. (2025) · Business & Information Systems Engineering · doi:10.1007/s12599-025-00945-3 · Cited by 92 · see citing works
Introduction to large language models (LLMs) for dementia care and research
Treder, M. S., Lee, S., & Tsvetanov, K. A. (2024) · Frontiers in Dementia · doi:10.3389/frdem.2024.1385303 · Cited by 63 · see citing works
An automated framework for assessing how well LLMs cite relevant medical references
Wu, K., Wu, E., Wei, K., Zhang, A., Casasola, A., Nguyen, T., Riantawan, S., Shi, P., Ho, D., & Zou, J. (2025) · Nature Communications · doi:10.1038/s41467-025-58551-6 · Cited by 72 · see citing works
Holistic evaluation of large language models for medical tasks with MedHELM
Bedi, S., Cui, H., Fuentes, M., Unell, A., Wornow, M., Banda, J. M., Kotecha, N., Keyes, T., Mai, Y., Oez, M., et al. (2026) · Nature Medicine · doi:10.1038/s41591-025-04151-2 · Cited by 59 · see citing works
ArgMed-Agents: Explainable Clinical Decision Reasoning with LLM Disscusion via Argumentation Schemes
Hong, S., Xiao, L., Zhang, X., & Chen, J. (2024) · 2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) · doi:10.1109/bibm62325.2024.10822109 · Cited by 21 · see citing works
FactPICO: Factuality Evaluation for Plain Language Summarization of Medical Evidence
Joseph, S., Chen, L., Trienes, J., Göke, H., Coers, M., Xu, W., Wallace, B., & Li, J. J. (2024) · Proceedings of the 62nd Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) · doi:10.18653/v1/2024.acl-long.459 · Cited by 17 · see citing works
Lechner, F., Kuhn, S., & Knitza, J. (2025) · International Journal of Rheumatic Diseases · doi:10.1111/1756-185x.70124 · Cited by 11 · see citing works
A Self-Evolving Framework for Multi-Agent Medical Consultation Based on Large Language Models
Chen, K., Qi, J., Huo, J., Tian, P., Meng, F., Yang, X., & Gao, Y. (2025) · ICASSP 2025 - 2025 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP) · doi:10.1109/icassp49660.2025.10889517 · Cited by 6 · see citing works
Zheng, T., Jiang, Z., Liu, J., & Feng, S. (2026) · npj Digital Medicine · doi:10.1038/s41746-026-02671-w · Cited by 1 · see citing works
Sun, C.-W. (2026) · JMIR Preprints · doi:10.2196/preprints.104400
- Authors
- Pal, A., Umapathi, L. K., & Sankarasubbu, M.
- Venue
- Proceedings of the 27th Conference on Computational Natural Language Learning (CoNLL)
- Published
- 2023
- Pages
- 314-334
- OpenAlex
- W4389519219
- Cited by
- 152
- References
- 18
- Citations by year
- 2026: 62 · 2025: 59 · 2024: 28 · 2023: 3
- FWCI
- 27.39
- Type
- conference paper
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- Conference on Computational Natural Language Learning (publishedVersion, cc-by)
- arXiv (Cornell University) (submittedVersion, cc-by)
- arXiv (Cornell University) (cc-by)
- Topics
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Physical Sciences › Computer Science › Artificial Intelligence › Topic Modeling
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Multimodal Machine Learning Applications
- Keywords
- hallucinations, large language models, medical domain, benchmark, hallucination detection, reasoning tests, medical examination, medical applications, LLM evaluation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review