The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Growth-inhibiting effects of 12 antibacterial agents and their mixtures on the freshwater microalga Pseudokirchneriella subcapitata
Abstract
The growth-inhibiting and binary joint effects of 12 antibacterial agents on the freshwater green alga Pseudokirchneriella subcapitata (Korschikov) Hindák were investigated over 72-h exposures. The toxicity values (the median inhibitory concentration value, in micromoles) in decreasing order of sensitivity were triclosan (0.0018) > triclocarban (0.054) > roxithromycin (0.056) > clarithromycin (0.062) > tylosin (0.20) > tetracycline (2.25) > chlortetracycline (3.49) > norfloxacin (5.64) > sulfamethoxazole (7.50) > ciprofloxacin (20.22) > sulfamethazine (31.26) > trimethoprim (137.78). Several of these antibacterial compounds would be toxic at the micrograms per liter concentrations reported in surface waters and sewage effluents. Simple additive effects were observed in binary mixtures of sulfonamides, and most tylosin, triclosan, or triclocarban combinations. Potentially synergistic effects were observed in binary mixtures of the same class, such as macrolides, tetracyclines, and fluoroquinolones, as well as in some combined drugs, such as trimethoprim and sulfonamides or tylosin and tetracyclines. Potentially antagonistic effects were only observed between tylosin and triclocarban, triclosan and norfloxacin, and triclocarban and norfloxacin. Although present at low concentrations in the aquatic environment, mixtures of these antibacterial agents can potentially affect algal growth in freshwater systems due to their combined action.
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Kolpin, D. W., Furlong, E. T., Meyer, M. T., Thurman, E. M., Zaugg, S. D., Barber, L. B., & Buxton, H. T. (2002) · Environmental Science & Technology · doi:10.1021/es011055j · Cited by 7,953
Occurrence of Antibiotics in the Aquatic Environment
Hirsch, R., Ternes, T., Haberer, K., & Kratz, K.-L. (1999) · Science of The Total Environment · doi:10.1016/s0048-9697(98)00337-4 · Cited by 2,140
Göbel, A., Thomsen, A., McArdell, C. S., Joss, A., & Giger, W. (2005) · Environmental Science & Technology · doi:10.1021/es048550a · Cited by 760
Cited by
Pharmaceuticals and personal care products (PPCPs): A review on environmental contamination in China
Liu, J.-L., & Wong, M.-H. (2013) · Environment International · doi:10.1016/j.envint.2013.06.012 · Cited by 1,357
Fluoroquinolone antibiotics: An emerging class of environmental micropollutants
Van Doorslaer, X., Dewulf, J., Van Langenhove, H., & Demeestere, K. (2014) · Science of The Total Environment · doi:10.1016/j.scitotenv.2014.08.075 · Cited by 819
González-Pleiter, M., Gonzalo, S., Rodea-Palomares, I., Leganés, F., Rosal, R., Boltes, K., Marco, E., & Fernández-Piñas, F. (2013) · Water Research · doi:10.1016/j.watres.2013.01.020 · Cited by 783
Antibiotics in the aquatic environments: A review of lakes, China
Liu, X., Lu, S., Guo, W., Xi, B., & Wang, W. (2018) · Science of The Total Environment · doi:10.1016/j.scitotenv.2018.01.271 · Cited by 665
McClellan, K., & Halden, R. U. (2010) · Water Research · doi:10.1016/j.watres.2009.12.032 · Cited by 522
Metadata
- Authors
- Yang, L.-H., Ying, G.-G., Su, H.-C., Stauber, J. L., Adams, M. S., & Binet, M. T.
- Venue
- Environmental Toxicology and Chemistry
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-05-01
- Volume
- 27
- Issue
- 5
- Pages
- 1201-1208
- ISSN
- 0730-7268 (ISSN-L)
- 1552-8618
- OpenAlex
- W2096756074
- Cited by
- 445
- References
- 3
- FWCI
- 17.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yang, L.-H., Ying, G.-G., Su, H.-C., Stauber, J. L., Adams, M. S., & Binet, M. T. (2008). Growth-inhibiting effects of 12 antibacterial agents and their mixtures on the freshwater microalga Pseudokirchneriella subcapitata. Environmental Toxicology and Chemistry. https://doi.org/10.1897/07-471.1
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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