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Multimodality imaging in nanomedicine and nanotheranostics
Open accessAbstract
Accurate diagnosis of tumors needs much detailed information. However, available single imaging modality cannot provide complete or comprehensive data. Nanomedicine is the application of nanotechnology to medicine, and multimodality imaging based on nanoparticles has been receiving extensive attention. This new hybrid imaging technology could provide complementary information from different imaging modalities using only a single injection of contrast agent. In this review, we introduce recent developments in multifunctional nanoparticles and their biomedical applications to multimodal imaging and theragnosis as nanomedicine. Most of the reviewed studies are based on the intrinsic properties of nanoparticles and their application in clinical imaging technology. The imaging techniques include positron emission tomography, single-photon emission computed tomography, computerized tomography, magnetic resonance imaging, optical imaging, and ultrasound imaging.
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“Different types of NPs for multimodal imaging have been established such as modified Gd2O3 NPs, gold NPs, 64CuInS/ZnS QDs, Bi2S3 NPs, and liposomal nanocarrier conjugated 99mTc [137,138].”
From Approaches to Improve EPR-Based Drug Delivery for Cancer Therapy and Diagnosis (2023) · cites this paper as [137]
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“In addition, multi-modal imaging systems can combine the high sensitivity of optical or nuclear imaging with the superior spatial resolution or tissue penetration of magnetic resonance, computed tomography, ultrasound, or photoacoustic imaging [33,34].”
Metadata
- Authors
- Li, X., Li, X., Zhang, X.-N., Li, X.-D., Chang, J., Zhang, X.-N., Li, X.-D., & Chang, J.
- Venue
- Cancer Biology & Medicine
- Publisher
- China Anti-cancer Association
- Published
- 2016
- Volume
- 13
- Issue
- 3
- Pages
- 339-348
- ISSN
- 2095-3941 (ISSN-L)
- PMC
- PMC5069837
- OpenAlex
- W2527625794
- Cited by
- 126
- References
- 46
- Citations by year
- 2026: 5 · 2025: 16 · 2024: 12 · 2023: 13 · 2022: 13 · 2021: 19 · 2020: 20 · 2019: 12 · 2018: 8 · 2017: 8
- FWCI
- 4.50
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Cancer Biology and Medicine (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Medical Imaging Techniques and Applications
- Physical Sciences › Engineering › Biomedical Engineering › Photoacoustic and Ultrasonic Imaging
- Keywords
- multimodal imaging, nanomedicine, theranostics, multifunctional nanoparticles, tumor diagnosis, hybrid imaging, positron emission tomography, single photon emission computed tomography, magnetic resonance imaging, optical imaging, ultrasonography, contrast media
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