Cited by 27Parathyroid Disorders and TreatmentsThyroid and Parathyroid SurgeryHormonal Regulation and Hypertension

The role of parathyroidectomy in treating hypertension and other cardiac manifestations of primary hyperparathyroidism

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Nelson, J. Alex, Alsayed, Mahmoud, Milas, Mira·2020·Gland Surgery

Abstract

Among many recognized sequelae of primary hyperparathyroidism (PHPT), cardiovascular disease remains incompletely understood as a consequence of disordered calcium and parathyroid hormone (PTH) metabolism. While population studies have identified trends that associate PHPT with hypertension, metabolic syndrome, and vascular system calcifications, the fundamental pathophysiology, natural history, and opportunity to reverse or cure the cardiovascular effects with parathyroidectomy are not well established. This chapter reviews the current knowledge of this field of interest within PHPT and summarizes key findings from dedicated investigations that have addressed the impact of parathyroid surgery on the cardiovascular system.

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Crossref · 10.21037/gs.2019.12.12

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Authors
Nelson, J. A., Alsayed, M., & Milas, M.
Affiliations
  • University of Michigan (US)
  • Banner - University Medical Center Phoenix (US)
Corresponding author
Nelson, J. Alex
Venue
Gland Surgery
Published
2020-02
Volume
9
Issue
1
Pages
136-141
ISSN
  • 2227-684X (ISSN-L)
  • 2227-8575
OpenAlex
W2998885849
Cited by
27
References
18
Citations by year
2026: 3 · 2025: 5 · 2024: 4 · 2023: 8 · 2022: 3 · 2021: 3 · 2020: 1
FWCI
2.35
Type
journal article
Language
en
Open access
Licence
cc-by-nc-nd
Locations
  • Gland Surgery (publishedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Nephrology › Parathyroid Disorders and Treatments
  • Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal Regulation and Hypertension
Keywords
primary hyperparathyroidism, parathyroidectomy, hypertension, cardiovascular disease, parathyroid hormone, calcium metabolism, vascular calcification, metabolic syndrome, cardiac involvement

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