Cited by 114Asthma and respiratory diseasesFood Allergy and Anaphylaxis ResearchImmune responses and vaccinations

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Vaccination and Allergic Disease: A Birth Cohort Study

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McKeever, Tricia M., Lewis, Sarah A., Smith, Chris, Hubbard, Richard·2004·American Journal of Public Health

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Abstract

OBJECTIVES: We examined the effect of vaccination for diphtheria; polio; pertussis and tetanus; or measles, mumps, and rubella on the incidence of physician-diagnosed asthma and eczema. METHODS: We used a previously established birth cohort in the West Midlands General Practice research database. RESULTS: We found an association between vaccination and the development of allergic disease; however, this association was present only among children with the fewest physician visits and can be explained by this factor. CONCLUSIONS: Our data suggest that currently recommended routine vaccinations are not a risk factor for asthma or eczema.

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Method
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Background
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Background
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Background
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Timing of routine vaccinations and the risk of childhood asthma
Spycher, B. D., Silverman, M. A., & Kuehni, C. E. (2008) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2008.06.037 · Cited by 10
Vaccines do not cause atopic dermatitis: A systematic review and meta-analysis
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Whole-cell pertussis vaccine in early infancy for the prevention of allergy in children
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Measles, mumps and rubella vs diphtheria–tetanus–acellular-pertussis–inactivated-polio–Haemophilus influenzae type b as the most recent vaccine and risk of early ‘childhood asthma’
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The Hygiene Hypothesis of Allergy and Asthma
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Identification and In Silico Characterization of a Conserved Peptide on Influenza Hemagglutinin Protein: A New Potential Antigen for Universal Influenza Vaccine Development
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“The server is a binary classiﬁer between allergens and non-allergens and it predicts allergenicity based on the amino acid principle properties such as size, hydrophobicity, helix, and beta-strand formations [73].”
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Next-generation multi-epitope subunit vaccine design: A computational approach utilizing two stable proteins to combat Human Metapneumovirus (HMPV)
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Computational Prediction of B cell epitopes of Mycobacterium tuberculosis – implications in vaccine design
Thangamariappan, E., Mohan, M., & Sundar, K. (2021) · Mediterranean Journal of Infection Microbes and Antimicrobials · doi:10.4274/mjima.galenos.2021.2021.23 · Cited by 2
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Authors: McKeever, T. M., Lewis, S. A., Smith, C., & Hubbard, R.
Affiliations: University of Nottingham (GB)
ORCID: McKeever, Tricia M.
Lewis, Sarah A.
Hubbard, Richard
Venue: American Journal of Public Health
Publisher: American Public Health Association
Published: 2004-06
Volume: 94
Issue: 6
Pages: 985-989
ISSN: 0090-0036 (ISSN-L)
1541-0048
DOI: 10.2105/ajph.94.6.985
PMC: PMC1448377
OpenAlex: W1982817031
Cited by: 114
References: 29
Citations by year: 2026: 1 · 2025: 2 · 2024: 3 · 2023: 4 · 2022: 4 · 2021: 14 · 2020: 13 · 2019: 7 · 2018: 5 · 2017: 4 · 2016: 6 · 2015: 5 · 2014: 2 · 2013: 3 · 2012: 5
FWCI: 4.33
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: American Journal of Public Health (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
Health Sciences › Medicine › Immunology and Allergy › Food Allergy and Anaphylaxis Research
Life Sciences › Immunology and Microbiology › Immunology › Immune responses and vaccinations
Keywords: vaccination, allergic diseases, asthma, atopic dermatitis, diphtheria, poliomyelitis, pertussis, tetanus, measles, mumps and rubella, routine childhood immunization, physician visits, birth cohort
MeSH terms: Asthma, Child, Child, Preschool, Eczema, England, Female, Humans, Infant, Infant, Newborn, Male, Physicians, Family, Vaccination, Cohort Studies

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Vaccination and Allergic Disease: A Birth Cohort Study

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