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Bone: Nature of the Calcium Phosphate Crystals and Cellular, Structural, and Physical Chemical Mechanisms in Their Formation
Abstract
Research Article| January 01, 2006 Bone: Nature of the Calcium Phosphate Crystals and Cellular, Structural, and Physical Chemical Mechanisms in Their Formation Melvin J. Glimcher Melvin J. Glimcher Laboratory for the Study of Skeletal Disorders and Rehabilitation, Department of Orthopaedic Surgery, Harvard Medical School and Children's Hospital, Boston, Massachusetts, 02115, U.S.A., e-mail: Melvin.Glimcher@childrens.harvard.edu Search for other works by this author on: GSW Google Scholar Reviews in Mineralogy and Geochemistry (2006) 64 (1): 223–282. https://doi.org/10.2138/rmg.2006.64.8 Article history first online: 14 Jul 2017 Cite View This Citation Add to Citation Manager Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Search Site Citation Melvin J. Glimcher; Bone: Nature of the Calcium Phosphate Crystals and Cellular, Structural, and Physical Chemical Mechanisms in Their Formation. Reviews in Mineralogy and Geochemistry 2006;; 64 (1): 223–282. doi: https://doi.org/10.2138/rmg.2006.64.8 Download citation file: Ris (Zotero) Refmanager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentBy SocietyReviews in Mineralogy and Geochemistry Search Advanced Search Calcium phosphate is the dominant solid mineral phase within the skeletal and dental tissues of vertebrates. This chapter concentrates on the structure and composition of the solid calcium inorganic orthophosphate (Ca–Pi) phase in bone and the mechanisms that are thought to induce the onset of this mineralization process as an example of biological mineralization in general. It is important to recognize that the Ca–Pi mineral phase is deposited in a living tissue and is a substance that is continuously being synthesized, resorbed and replaced by the action of living cells. Therefore, the composition, structure and other properties of the solid... You do not have access to this content, please speak to your institutional administrator if you feel you should have access.
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Citations
Cites
THE CHEMICAL DYNAMICS OF BONE MINERAL
NEUMAN, W. F., & NEUMAN, M. W. (1959) · The American Journal Of The Medical Sciences · doi:10.1097/00000441-195912000-00030 · Cited by 1,032
The Possible Significance of Hexosephosphoric Esters in Ossification
Robison, R. (1923) · Biochemical Journal · doi:10.1042/bj0170286 · Cited by 810
Mechanisms of calcification: role of collagen, polyphosphates, and phosphatase
Fleish, H., & Neuman, W. F. (1961) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1961.200.6.1296 · Cited by 444
Disaggregation of bone into crystals
Weiner, S., & Price, P. A. (1986) · Calcified Tissue International · doi:10.1007/bf02555173 · Cited by 322
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Wegst, U. G. K., Bai, H., Saiz, E., Tomsia, A. P., & Ritchie, R. O. (2015) · Nature Materials · doi:10.1038/nmat4089 · Cited by 4,721
Hierarchical Structures of Bone and Bioinspired Bone Tissue Engineering
Liu, Y., Luo, D., & Wang, T. (2016) · Small · doi:10.1002/smll.201600626 · Cited by 482
Functional Grading of Mineral and Collagen in the Attachment of Tendon to Bone
Genin, G. M., Kent, A., Birman, V., Wopenka, B., Pasteris, J. D., Marquez, P. J., & Thomopoulos, S. (2009) · Biophysical Journal · doi:10.1016/j.bpj.2009.05.043 · Cited by 331
Incorporation of excess gadolinium into human bone from medical contrast agents
Darrah, T. H., Prutsman-Pfeiffer, J. J., Poreda, R. J., Ellen Campbell, M., Hauschka, P. V., & Hannigan, R. E. (2009) · Metallomics · doi:10.1039/b905145g · Cited by 299
Mineralization of Bones and Teeth
Boskey, A. L. (2007) · Elements · doi:10.2113/gselements.3.6.385 · Cited by 278
Metadata
- Authors
- Glimcher, M. J.
- Venue
- Reviews in Mineralogy and Geochemistry
- Publisher
- Mineralogical Society of America
- Published
- 2006-01-01
- Volume
- 64
- Issue
- 1
- Pages
- 223-282
- ISSN
- 1529-6466 (ISSN-L)
- OpenAlex
- W1991985237
- Cited by
- 326
- References
- 4
- FWCI
- 5.36
- Type
- journal article
- Language
- en
- Open access
- closed
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