In Vivo Gene Delivery in the Retina Using Polyethylenimine

Melanopsin-Containing Retinal Ganglion Cells: Architecture, Projections, and Intrinsic Photosensitivity

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Rational siRNA design for RNA interference

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Polyethylenimine-based non-viral gene delivery systems

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Diminished Pupillary Light Reflex at High Irradiances in Melanopsin-Knockout Mice

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Ectopic Expression of a Microbial-Type Rhodopsin Restores Visual Responses in Mice with Photoreceptor Degeneration

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Viral gene therapy strategies: from basic science to clinical application

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Cells in the pretectal olivary nucleus are in the pathway for the direct light reflex of the pupil in the rat

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Persistent transgene product in retina, optic nerve and brain after intraocular injection of rAAV

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Gene delivery to the eye using adeno-associated viral vectors

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Luminance and darkness detectors in the olivary and posterior pretectal nuclei and their relationship to the pupillary light reflex in the rat

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Non-image-forming ocular photoreception in vertebrates

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Delivery of Ciliary Neurotrophic Factor via Lentiviral-Mediated Transfer Protects Axotomized Retinal Ganglion Cells for an Extended Period of Time

van Adel, B. A., Kostic, C., Déglon, N., Ball, A. K., & Arsenijévic, Y. (2003) · Human Gene Therapy · doi:10.1089/104303403321070801 · Cited by 114 · see citing works

Adeno-Associated Virus-Vectored Gene Therapy for Retinal Disease

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Viral-based modelling and correction of neurodegenerative diseases by RNA interference

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The retinal pigment epithelium as a developmental regulator of the neural retina

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Neuroticism and the Effect of Stress on the Pupillary Light Reflex

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Non-viral gene therapy: Gains and challenges of non-invasive administration methods

Földvári, M., Chen, D.-W., Nafissi, N., Calderon-Nieva, D., Narsineni, L., & Rafiee, A. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.12.012 · Cited by 240 · see citing works

Vector platforms for gene therapy of inherited retinopathies

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Gene Therapy for Retinal Degenerative Diseases: Progress, Challenges, and Future Directions

Drag, S., Dotiwala, F., & Upadhyay, A. K. (2023) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.64.7.39 · Cited by 145 · see citing works

Systemic Delivery of DNA or siRNA Mediated by Linear Polyethylenimine (L-PEI) Does Not Induce an Inflammatory Response

Bonnet, M.-E., Erbacher, P., & Bolcato‐Bellemin, A. (2008) · Pharmaceutical Research · doi:10.1007/s11095-008-9693-1 · Cited by 146 · see citing works

Nanoparticle-based technologies for retinal gene therapy

Adijanto, J., & Naash, M. I. (2015) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2014.12.028 · Cited by 107 · see citing works

Nanomedicine and drug delivery to the retina: current status and implications for gene therapy

Tawfik, M., Chen, F., Goldberg, J. L., & Sabel, B. A. (2022) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-022-02287-3 · Cited by 94 · see citing works

In vivonucleic acid delivery with PEI and its derivatives: current status and perspectives

Lai, W. (2011) · Expert Review of Medical Devices · doi:10.1586/erd.10.83 · Cited by 77 · see citing works

Nanoparticles-mediated CRISPR-Cas9 gene therapy in inherited retinal diseases: applications, challenges, and emerging opportunities

Chien, Y., Hsiao, Y., Chou, S., Lin, T.-Y., Yarmishyn, A. A., Lai, W., Lee, M., Lin, Y., Lin, T.-W., Hwang, D., et al. (2022) · Journal of Nanobiotechnology · doi:10.1186/s12951-022-01717-x · Cited by 58 · see citing works

Immune responses to gene editing by viral and non-viral delivery vectors used in retinal gene therapy

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Gene delivery to the retina: focus on non-viral approaches

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Non‐viral retinal gene therapy: a review

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Efficient siRNA Delivery by the Cationic Liposome DOTAP in Human Hematopoietic Stem Cells Differentiating into Dendritic Cells

Martino, S., di Girolamo, I., Tiribuzi, R., D′Angelo, F., Datti, A., & Orlacchio, A. (2009) · BioMed Research International · doi:10.1155/2009/410260 · Cited by 37 · see citing works

Correction of Monogenic and Common Retinal Disorders with Gene Therapy

Sengillo, J. D., Justus, S., Cabral, T., & Tsang, S. H. (2017) · Genes · doi:10.3390/genes8020053 · Cited by 37 · see citing works

Next-Generation Nanomedicine Approaches for the Management of Retinal Diseases

Mahaling, B., Low, S. W. Y., Ch, S., Addi, U. R., Ahmad, B. U., Connor, T. B., Mohan, R. R., Biswas, S., & Chaurasia, S. S. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15072005 · Cited by 35 · see citing works

Non-viral siRNA delivery into the mouse retina in vivo

Turchinovich, A. A., Zoidl, G., & Dermietzel, R. (2010) · BMC Ophthalmology · doi:10.1186/1471-2415-10-25 · Cited by 35 · see citing works

Fostering the unleashing potential of nanocarriers-mediated delivery of ocular therapeutics

Datta, D., Bandi, S. P., Colaco, V., Dhas, N. L., Reddy, D. S., & Vora, L. K. (2024) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2024.124192 · Cited by 40 · see citing works

Expression of green fluorescent protein in the chicken using in vivo transfection of the piggyBac transposon

Jordan, B. J., Vogel, S., Stark, M. R., & Beckstead, R. B. (2014) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2014.01.016 · Cited by 27 · see citing works

Nanoparticle-mediated gene therapy as a novel strategy for the treatment of retinoblastoma

Mandal, M., Banerjee, I., & Mandal, M. (2022) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2022.112899 · Cited by 26 · see citing works

A New Approach of Delivering siRNA to the Cornea and its Application for Inhibiting Herpes Simplex Keratitis

Li, Z., Duan, F., Li, L., Huang, Q., & Wu, K. (2014) · Current Molecular Medicine · doi:10.2174/1566524014666141021145909 · Cited by 25 · see citing works

Nano-vectors for the ocular delivery of nucleic acid-based therapeutics

Khar, R. K., Warsi, M. H., Akhter, S., Ahmad, F., Jain, G. K., Mallick, N., & Pathan, S. (2010) · Indian Journal of Pharmaceutical Sciences · doi:10.4103/0250-474x.84575 · Cited by 26 · see citing works

Ocular Gene Delivery Systems Using Ternary Complexes of Plasmid DNA, Polyethylenimine, and Anionic Polymers

Kurosaki, T., Uematsu, M., Shimoda, K., Suzuma, K., Nakai, M., Nakamura, T., Kitahara, T., Kitaoka, T., & Sasaki, H. (2013) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b12-00728 · Cited by 24 · see citing works

Suprachoroidally Delivered DNA Nanoparticles Transfect Retina and Retinal Pigment Epithelium/Choroid in Rabbits

Kansara, V. S., Cooper, M. J., Sesenoglu‐Laird, O., Muya, L. W., Moen, R. C., & Ciulla, T. A. (2020) · Translational Vision Science & Technology · doi:10.1167/tvst.9.13.21 · Cited by 24 · see citing works

Non-image-forming photoreceptors improve visual orientation selectivity and image perception

Shi, Y., Zhang, J., Li, X., Han, Y., Guan, J., Li, Y., Shen, J., Tzvetanov, T., Yang, D., Luo, X., et al. (2024) · Neuron · doi:10.1016/j.neuron.2024.11.015 · Cited by 29 · see citing works

Application of galangin, an active component of Alpinia officinarum Hance (Zingiberaceae), for use in drug-eluting stents

Lee, J., Lee, J., Yim, N., Han, J., & Yeul, J. (2017) · Scientific Reports · doi:10.1038/s41598-017-08410-2 · Cited by 22 · see citing works

The Future of Nanomaterials Tackling the Challenge of Delivering Nucleic Acids to the Retina

Hurst, J., Adams, F., & Schnichels, S. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202407173 · Cited by 21 · see citing works

Non-viral-mediated suppression of AMIGO3 promotes disinhibited NT3-mediated regeneration of spinal cord dorsal column axons

Almutiri, S., Berry, M., Logan, A., & Ahmed, Z. (2018) · Scientific Reports · doi:10.1038/s41598-018-29124-z · Cited by 20 · see citing works

Nanoparticle‐motivated gene delivery for ophthalmic application

Mitra, R. N., Zheng, M., & Han, Z. (2015) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1356 · Cited by 18 · see citing works

New Method for Efficient siRNA Delivery in Retina Explants: Reverse Magnetofection

Bassetto, M., Sen, M., Poulhès, F., Arango‐González, B., Bonvin, E., Sapet, C., Ueffing, M., & Zelphati, O. (2021) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.1c00132 · Cited by 17 · see citing works

Pigment Epithelium-Derived Factor Promotes Axon Regeneration and Functional Recovery After Spinal Cord Injury

Stevens, A. R., Ahmed, U., Vigneswara, V., & Ahmed, Z. (2019) · Molecular Neurobiology · doi:10.1007/s12035-019-1614-2 · Cited by 15 · see citing works

Minicircle Delivery to the Neural Retina as a Gene Therapy Approach

Staurenghi, F., McClements, M. E., Salman, A., & MacLaren, R. E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911673 · Cited by 14 · see citing works

Conjugates of Recombinant Protein‐Based Polymers: Combining Precision with Chemical Diversity

Dagan, H., Strugach, D. S., & Amiram, M. (2022) · Advanced NanoBiomed Research · doi:10.1002/anbr.202100142 · Cited by 13 · see citing works

Inhibition ofPAX2Gene Expression by siRNA (Polyethylenimine) in Experimental Model of Obstructive Nephropathy

Li, L., Wu, Y., Wang, C., & Zhang, W. (2012) · Renal Failure · doi:10.3109/0886022x.2012.723662 · Cited by 10 · see citing works

Non-Viral Delivery Systems to Transport Nucleic Acids for Inherited Retinal Disorders

Jony, M. J. H., Joshi, A., Dash, A. K., & Shukla, S. (2025) · Pharmaceuticals · doi:10.3390/ph18010087 · Cited by 10 · see citing works

Targeting Promoter-Associated Noncoding RNA In Vivo

Civenni, G. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-6716-2_15 · Cited by 8 · see citing works

Targeted Delivery of Nucleic Acid Therapeutics via Nonviral Vectors

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A linear polyethylenimine mediated siRNA-based therapy targeting human epidermal growth factor receptor in SPC-A1 xenograft mice

Zhang, P., Xu, N., Zhou, L., Xu, X., Wang, Y., Li, K., Zeng, Z., Wang, X., Zhang, X., & Bai, C. (2013) · Translational Respiratory Medicine · doi:10.1186/2213-0802-1-2 · Cited by 6 · see citing works

Nano-Based Drug Approaches to Proliferative Vitreoretinopathy Instead of Standard Vitreoretinal Surgery

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Application Prospects for Synthetic Nanoparticles in Optogenetic Retinal Prosthetics

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The Contribution of Nanomedicine in Ocular Oncology

Spyratou, E., Margarita, T., Droulias, A., Zachou, M.-E., & EFSTATHOPOULOS, E. P. (2025) · Cancers · doi:10.3390/cancers17071186 · Cited by 3 · see citing works

Gentherapie in der Augenheilkunde

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RNAi in Ocular Diseases

Turchinovich, A. A., Zoidl, G., & Dermietzel, R. (2013) · doi:10.1002/9781118610749.ch18 · Cited by 2 · see citing works

Non-viral gemini surfactant-phospholipid nanoparticles for topical gene delivery to the retina

Alqawlaq, S. (2013) · UWSpace (University of Waterloo)

The Role of Telomere Maintenance in Adult Mammalian Acute Central Nervous System Injury and Retinal Ganglion Cell Apoptosis

Lysko, M. D. (2016) · TSpace (University of Toronto)

The role of novel genes in CNS axon regeneration

Almutiri, S. (2017) · University of Birmingham Institutional Research Archive (University of Birmingham)

Studies on retina-specific gene expression

Reinisalo, M. (2012) · UEF eRepo (University of Eastern Finland)

Pathophysiology and gene therapy of the optic neuropathy in Wolfram Syndrome

Jagodzinska, J. (2016) · doi:10.70675/d5ad003czb010z456bz8738za3feee533351

Linear Polyethylenimine–Based DNA Nanoparticle Delivery Into Mouse Retinas

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Optimization of Lentiviral Gene Delivery to the Retinal Pigment Epithelium in vivo

Haire, S. E., Elder, I., Saban, D. R., Janssen, J. J. M., & Timmers, A. M. (2003) · Investigative Ophthalmology & Visual Science

Rapid And Substantial Gene Delivery Into Cornea In Vivo And In Vitro With Linearized Polyethyleneimine Nanoparticles

Gupta, R., Tandon, A., Hansen, E., Cebulko, T. C., Hemmat, Y. J., Fortune, J. A., Klibanov, A. M., & Mohan, R. R. (2011) · Investigative Ophthalmology & Visual Science · Cited by 6 · see citing works

Gene delivery to the primate retina

Byrne, L. C. (2019) · Investigative Ophthalmology & Visual Science

Non-invasive, Targeted Gene Delivery to Retina and Retinal Endothelial Cells and Enhanced Live Retinal Imaging Using Contrast-enhanced Ultrasound Delivery System

Cowan, C. E., Kovas, B., Feinstein, S. B., MacCumber, M., & Xu, S. (2012) · Investigative Ophthalmology & Visual Science