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Genes associated with Alzheimer's disease: an overview and current status
Open accessAbstract
Alzheimer's disease (AD) is a progressive, neurodegenerative disease and the most common form of dementia in elderly people. It is an emerging public health problem that poses a huge societal burden. Linkage analysis was the first milestone in unraveling the mutations in APP, PSEN1, and PSEN2 that cause early-onset AD, followed by the discovery of apolipoprotein E-ε4 allele as the only one genetic risk factor for late-onset AD. Genome-wide association studies have revolutionized genetic research and have identified over 20 genetic loci associated with late-onset AD. Recently, next-generation sequencing technologies have enabled the identification of rare disease variants, including unmasking small mutations with intermediate risk of AD in PLD3, TREM2, UNC5C, AKAP9, and ADAM10. This review provides an overview of the genetic basis of AD and the relationship between these risk genes and the neuropathologic features of AD. An understanding of genetic mechanisms underlying AD pathogenesis and the potentially implicated pathways will lead to the development of novel treatment for this devastating disease.
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“It takes 10–20 years for AD to manifest itself (e.g., [5, 69]).”
From Current therapeutics for Alzheimer’s disease and clinical trials (2024) · cites this paper as [5]
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Corder, E. H., Saunders, A. M., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Small, G. W., Roses, A. D., Haines, J. L., & Pericak-Vance, M. A. (1993) · Science · doi:10.1126/science.8346443 · Cited by 9,429
Goate, A., Chartier-Harlin, M.-C., Mullan, M., Brown, J., Crawford, F., Fidani, L., Giuffra, L., Haynes, A., Irving, N., James, L., et al. (1991) · Nature · doi:10.1038/349704a0 · Cited by 4,659
Meta-Analysis of 74,046 Individuals Identifies 11 New Susceptibility Loci for Alzheimer’s Disease
(EADI), E. A. D. I., Lambert, J.-C., (GERAD), G. A. E. R. I. A. D., Alzheimer's Disease Genetic Consortium (ADGC), (CHARGE), C. F. H. A. A. R. I. G. E., Ibrahim-Verbaas, C. A., Harold, D., Naj, A. C., Sims, R., Bellenguez, C., et al. (2013) · Nature Genetics · doi:10.1038/ng.2802 · Cited by 4,336
Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease
Saunders, A. M., Strittmatter, W. J., Schmechel, D., St. George-Hyslop, P. H., Pericak-Vance, M. A., Joo, S. H., Rosi, B. L., Gusella, J. F., Crapper-MacLachlan, D. R., Alberts, M. J., et al. (1993) · Neurology · doi:10.1212/wnl.43.8.1467 · Cited by 3,786
Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Hamshere, M. L., Pahwa, J. S., Moskvina, V., Dowzell, K., Williams, A., et al. (2009) · Nature Genetics · doi:10.1038/ng.440 · Cited by 3,326
Blennow, K., de Leon, M. J., & Zetterberg, H. (2006) · The Lancet · doi:10.1016/s0140-6736(06)69113-7 · Cited by 3,134
TREM2 Variants in Alzheimer's Disease
Guerreiro, R., Wojtas, A., Bras, J., Carrasquillo, M., Rogaeva, E., Majounie, E., Cruchaga, C., Sassi, C., Kauwe, J. S. K., Younkin, S., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1211851 · Cited by 3,020
Variant of TREM2 Associated with the Risk of Alzheimer's Disease
Jonsson, T., Stefansson, H., Steinberg, S., Jonsdottir, I., Jonsson, P. V., Snaedal, J., Bjornsson, S., Huttenlocher, J., Levey, A. I., Lah, J. J., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1211103 · Cited by 2,558
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
the European Alzheimer's Disease Initiative Investigators, Lambert, J.-C., Heath, S., Even, G., Campion, D., Sleegers, K., Hiltunen, M., Combarros, O., Zelenika, D., Bullido, M. J., et al. (2009) · Nature Genetics · doi:10.1038/ng.439 · Cited by 2,234
Initiative, T. A. D. N., Hollingworth, P., CHARGE consortium, EADI1 consortium, Harold, D., Sims, R., Gerrish, A., Lambert, J.-C., Carrasquillo, M. M., Abraham, R., et al. (2011) · Nature Genetics · doi:10.1038/ng.803 · Cited by 1,997
Research works printed but not linked: 1
- [113]Rajagopalan P Hibar DP Thompson PM TREM2 and neurodegenerative disease N Engl J Med 2013 369 16 1565 1567 24131186 PMC4024453
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Items 201–300 of 311
Pharmacogenomic Strategies in Alzheimer’s Disease: An In-Depth Review
Zhou, Y., Peng, S., Wang, H., Cai, X., & Wang, Q. (2024) · Journal of Medical Sciences and Interdisciplinary Research · doi:10.51847/q8jx01pn0m · Cited by 6
Berg, C. N., Sinha, N., & Gluck, M. A. (2019) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2019.00073 · Cited by 6
Stanciu, G. D., Ababei, D. C., Rusu, R.-N., Bild, V., & Tamba, B.-I. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14061270 · Cited by 6
Cognitive outcome measures for tracking Alzheimer's disease in Down syndrome
Fleming, V., Hom, C. L., Clare, I. C. H., Hurd-Thomas, S. L., Krinsky‐McHale, S. J., Handen, B. L., & Hartley, S. L. (2022) · International review of research in developmental disabilities · doi:10.1016/bs.irrdd.2022.05.006 · Cited by 8
Identification of genetic loci shared between Alzheimer’s disease and hypertension
Sullivan, M., Deng, H., & Greenbaum, J. (2022) · Molecular Genetics and Genomics · doi:10.1007/s00438-022-01949-4 · Cited by 6
Advances in the Study of APOE and Innate Immunity in Alzheimer’s Disease
Li, Y., Chang, J., Chen, X., Liu, J., & Zhao, L. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-230179 · Cited by 6
Tan, T., Lin, X., Tu, K., Tang, J., Yin, S., Dai, L., Lei, P., Dong, B., Hu, H., Fan, Y., et al. (2018) · BMC Genomics · doi:10.1186/s12864-018-5183-y · Cited by 7
The Role of Genetics in Alzheimer's Disease and Parkinson's Disease
Porter, T., Gozt, A., Mastaglia, F. L., & Laws, S. M. (2019) · Wiley eBooks · doi:10.1002/9781119356752.ch15 · Cited by 6
Eldik, L. J. V., Siemers, E., Collins, E. C., Gold, M., Henley, D. B., Johannsen, P., Möbius, H. J., Shulman, M. B., Zhou, J., Carrillo, M. C., et al. (2024) · Alzheimer s & Dementia Translational Research & Clinical Interventions · doi:10.1002/trc2.70014 · Cited by 5
SIGEL: a context-aware genomic representation learning framework for spatial genomics analysis
Li, W., Zhu, M., Xu, Y., Huang, M., Wang, Z., Chen, J., Wu, H., & Sun, X. (2025) · Genome biology · doi:10.1186/s13059-025-03748-7 · Cited by 6
Parithathvi, A., Harshitha, P., Mumbrekar, K. D., & Dsouza, H. S. (2025) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-025-01613-6 · Cited by 6
Puzzo, D., & Conti, F. (2021) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2021.684977 · Cited by 6
Understanding the Intricate Role of Exosomes in Pathogenesis of Alzheimer’s Disease
Chauhan, S., Behl, T., Sehgal, A., Singh, S., Sharma, N., Gupta, S., Albratty, M., Najmi, A., Meraya, A. M., & Alhazmi, H. A. (2022) · Neurotoxicity Research · doi:10.1007/s12640-022-00621-4 · Cited by 6
In silico Characterization of Predominant Genes Involved in Early Onset of Alzheimer's Disease
Sachdeva, P., & Ahmad, F. (2021) · The Journal of Neurobehavioral Sciences · doi:10.4103/jnbs.jnbs_34_21 · Cited by 5
Mécanismes, facteurs de risque et stratégies thérapeutiques dans la maladie d’Alzheimer
Maître, M., Klein, C., & Mensah‐Nyagan, A. G. (2017) · NPG. Neurologie, psychiatrie, gériatrie/NPG · doi:10.1016/j.npg.2016.12.006 · Cited by 5
KIF5A and KLC1 expression in Alzheimer’s disease: relationship and genetic influences
Hares, K. M., Miners, J. S., Scolding, N. J., Love, S., & Wilkins, A. (2019) · AMRC Open Research · doi:10.12688/amrcopenres.12861.1 · Cited by 5
Singh, H. N., Swarup, V., Dubey, N. K., Jha, N. K., Singh, A. K., Lo, W., & Kumar, S. (2022) · Biomedicines · doi:10.3390/biomedicines10030611 · Cited by 6
Highly accurate disease diagnosis and highly reproducible biomarker identification with PathFormerPreprint
Li, F., Dong, Z., Zhao, Q., Payne, P., Province, M. A., Cruchaga, C., Zhang, M., Zhao, T., & Chen, Y. (2023) · Research Square · doi:10.21203/rs.3.rs-3576068/v1 · Cited by 6
Self-citationPanda, M., Fakitsa, M., Markaki, M., & Tavernarakis, N. (2025) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2025.115655 · Cited by 4
Niño-Rivero, S., Cabral, R., Fleitas, J., Alcalde-Ahlig, L., Castaño, E. M., Morelli, L., McGregor, R., Galeano, P., & Lagos, P. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262210944 · Cited by 5
Al-Ayari, E. A., Shehata, M. G., El-Hadidi, M. S., & Shaalan, M. G. (2023) · Scientific Reports · doi:10.1038/s41598-023-46250-5 · Cited by 4
Impact of prior exposures on biomarkers of blast during military tactical training
Wang, Z., Sun, S., Liu, Q., Kranfli, A. A., Nemes, J., Sullan, M. J., Hoisington, A. J., Brenner, L. A., Skotak, M., LaValle, C. R., et al. (2025) · Frontiers in Neurology · doi:10.3389/fneur.2025.1589742 · Cited by 5
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G., S., Raj, A., TABASSUM, S., & Chhakchhuak, D. (2021) · International Journal of Current Pharmaceutical Research · doi:10.22159/ijcpr.2021v13i5.1906 · Cited by 4
Precision medicines for the treatment of Alzheimer's disease
Kanthale, S. B., Kendre, P. N., Vibhute, S. K., Jain, S. P., & Tiwari, S. S. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13205-6.00025-x · Cited by 4
Alzheimer's Disease and Effects of ABCA7 Polymorphisms: A Review
Gialama, V., Siokas, V., Liampas, I., Tsouris, Z., Stamati, P., Aslanidou, P., Provatas, A., Tsimourtou, V., Xiromerisiou, G., Bogdanos, D. P., et al. (2024) · Journal of Integrative Neuroscience · doi:10.31083/j.jin2309164 · Cited by 4
Abdulghani, M. F., Barzegari, R., Almagharbeh, W. T., Yazdani, Z., Ghotbabadi, A. A., Bagheri, S. H. S., Alnaiem, M., & Dehghan, M. (2025) · Psychogeriatrics · doi:10.1111/psyg.70007 · Cited by 4
Kim, D., Gim, J., Mishra, A., Lee, K., Cho, Y., & Kim, H. (2017) · Genes & Genomics · doi:10.1007/s13258-017-0524-9 · Cited by 4
Genetics of common complex diseases: a view from Iceland
Arnar, D. O., & Pálsson, R. (2017) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2017.03.018 · Cited by 7
The anti-Alzheimer compounds from tempeh oil in LPS-induced neuronal Schwann cells
Limanjaya, E. C., Subali, D., & Yanti, Y. (2022) · Journal of Ethnic Foods · doi:10.1186/s42779-022-00163-2 · Cited by 4
Cai, S., Cheng, B., Li, K., Li, Y., Zhang, A., Sun, J., Su, Y., Li, M., Bao, Q., Zhang, Y., et al. (2023) · BMC Geriatrics · doi:10.1186/s12877-023-04214-4 · Cited by 4
Fueling Alzheimer’s Disease: Where Does Immunometabolism Stand?
Correia, S. C., Perry, G. L., & Moreira, P. I. (2024) · Journal of Alzheimer s Disease · doi:10.3233/jad-240787 · Cited by 3
Brokate-Llanos, A. M., Sanchez-Ibañez, M., Pérez‐Jiménez, M. M., Monje, J. M., Gómez-Marín, C., Caro, C., Vivar‐Rios, C., Moreno-Mateos, M. A., García‐Martín, M. L., Muñoz, M. J., et al. (2024) · G3 Genes Genomes Genetics · doi:10.1093/g3journal/jkae040 · Cited by 3
Sun, Y., Jiang, M., Xiang, L., Miao, Y., Du, H., Zhang, T., Ma, X., Zhang, Y., & Meng, H. (2024) · Journal of Molecular Neuroscience · doi:10.1007/s12031-024-02225-3 · Cited by 4
Abdulkadir, T. S., & Ayo, J. O. (2024) · Comparative Clinical Pathology · doi:10.1007/s00580-024-03603-4 · Cited by 3
Bioinformatics in the Identification of Novel Targets and Pathways in Neurodegenerative Diseases
Paananen, J. (2017) · Current Genetic Medicine Reports · doi:10.1007/s40142-017-0115-8 · Cited by 3
[Relationship between Oral Microbiota and Alzheimer's Disease].
Li, Y.-C., Liu, Y., Chen, F., Chu, M., & Chen, X.-C. (2022) · 四川大学学报：医学版 · doi:10.12182/20220360304 · Cited by 6
Pharmacogenomic Approaches in Alzheimer's Disease: A Comprehensive Review
Bhat, R., Varshini, V., Himasvi, H., & Shabaraya, R. (2023) · International Journal of Pharmaceutical and Phytopharmacological Research · doi:10.51847/qdmsgl63u7 · Cited by 3
Bauer, C., Duplan, E., George‐Hyslop, P. S., & Checler, F. (2023) · Cells · doi:10.3390/cells12242802 · Cited by 2
Sharma, P., & Pienaar, I. S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-804078-2.00024-6 · Cited by 3
Variance components genetic association test for zero‐inflated count outcomes
Goodman, M. O., Chibnik, L. B., & Cai, T. (2018) · Genetic Epidemiology · doi:10.1002/gepi.22162 · Cited by 3
Bei, J., Miranda-Morales, E. G., Gan, Q., Qiu, Y., Husseinzadeh, S., Liew, J. Y., Chang, Q., Krishnan, B., Gaitas, A., Yuan, S., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.04.03.535441 · Cited by 3
Yakubu, A., Adedeji, I. A., Maduka, O. C., Jegede, A. S., & Adebamowo, C. (2024) · BMC Medical Ethics · doi:10.1186/s12910-024-01141-w · Cited by 3
The causal role of lipids in dementia: A Mendelian randomization study
Su, B., He, Z., Mao, L., & Huang, X. (2025) · Journal of Alzheimer s Disease Reports · doi:10.1177/25424823241312106 · Cited by 2
Expression of MAPK and inflammasomes in cells of the brain in experimental Alzheimer's disease
Gorina, Y. V., Lopatina, O. L., Komleva, Y. К., Игоревич, Ч. А., & Salmina, A. B. (2017) · Annals of Clinical and Experimental Neurology · doi:10.17816/acen.2017.4.5 · Cited by 2
Arbeev, K. G., Ukraintseva, S. V., Bagley, O., Duan, H., Wu, D., Akushevich, I. V., Stallard, E., Kulminski, A. M., Christensen, K., Feitosa, M. F., et al. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1236509 · Cited by 3
Schultheis, N., Connell, A., Kapral, A., Becker, R. J., Mueller, R., Shah, S., O’Donnell, M., Roseman, M., Swanson, L., DeGuara, S., et al. (2024) · iScience · doi:10.1016/j.isci.2024.110256 · Cited by 4
Speech signal’s phase information based Alzheimer’s disease detection using deep learning
Kumar, M., Sushant, & Yadav, A. K. (2025) · International Journal of Speech Technology · doi:10.1007/s10772-025-10193-1 · Cited by 2
Villalba, A. C., Valencia, J. G., Ramos, C., Cuastumal, A. R., Aguillon, D. F., Aguirre–Acevedo, D. C., Madrigal, L., & Lopera, F. J. (2019) · Journal of Alzheimer s Disease Reports · doi:10.3233/adr-190139 · Cited by 2
Barek, M. A., Aziz, M. A., Jafrin, S., & Islam, M. S. (2021) · Meta Gene · doi:10.1016/j.mgene.2021.100868 · Cited by 2
Altuna, M., Larumbe, R., Zelaya, M. V., Moreno, S., García-Solaesa, V., Mendióroz, M., Ramos, M. A., & Erro, M. E. (2022) · Journal of Neurology · doi:10.1007/s00415-022-11125-8 · Cited by 2
Keskin, T., Avşar, O., Eliaçık, S., & Tan, F. U. (2024) · Nucleosides Nucleotides & Nucleic Acids · doi:10.1080/15257770.2024.2311783 · Cited by 4
Bin, Y., Zhu, Q., Li, M., & Xia, J. (2019) · IEEE Access · doi:10.1109/access.2019.2935515 · Cited by 3
Stoychev, K., Stoimenova-Popova, M. Y., Chumpalova, P. G., Ilieva, L., Swamad, M., & Kamburova-Martinova, Z. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00857 · Cited by 2
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Avramouli, A., Polychronidou, E., & Vlamos, P. (2022) · EMBnet journal · doi:10.14806/ej.27.0.1011
Afnan, U., Khan, M. S., Swaliha, C. A., Manzoor, U., Mumtaz, I., Dar, M. J., & Maqbool, T. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-15177-4.00002-9 · Cited by 1
Zeng, J., Gao, Z., Xiong, X., Hou, X., Qin, H., Liu, Y., Bowman, H., Ritchie, C. W., O'Brien, J. T., & Su, L. (2024) · Journal of Alzheimer s Disease · doi:10.1177/13872877241299124 · Cited by 1
Kavey, M. R. H., Hossain, M. A., Shohag, M. S. R., Ansari, I. A., Ansari, S. A., Alkahtani, H. M., Hossain, A., & Rahman, M. H. (2025) · In Silico Pharmacology · doi:10.1007/s40203-025-00434-1 · Cited by 2
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Lee, H. G., Kim, J., Jang, C., & Shin, M. (2026) · BioDrugs · doi:10.1007/s40259-025-00761-x · Cited by 1
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Dutta, B., Loo, S., Kam, A., Liu, C., & Tam, J. P. (2026) · Biochemistry · doi:10.1021/acs.biochem.5c00763 · Cited by 1
Yan, X., Tang, S., Yi, X., & Wang, J. (2026) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2026.139691 · Cited by 1
Froes, B. R., Pina, J. G., Alves, M. D. M., Mançano, A. S. F., Cardoso, F. C., & Sciani, J. M. (2026) · Pharmaceutics · doi:10.3390/pharmaceutics18060696 · Cited by 1
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Tong, T. M., Dao, T. T. H., Doan, L. P., Nguyen, D., Nguyen, Q. T., Do, T. T., Truong, K. D., Phan, M., Nguyen, H., Tran, T. C., et al. (2021) · International Journal of Neuroscience · doi:10.1080/00207454.2020.1870974 · Cited by 1
Pourshaikhali, S., Saleh-Gohari, N., Saeidi, K., & Soofiabadi, M. F. (2022) · Basic and Clinical Neuroscience Journal · doi:10.32598/bcn.2022.206.2 · Cited by 1
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Aswar, U. M., Rathod, K., & Mathure, D. M. (2024) · Central Nervous System Agents in Medicinal Chemistry · doi:10.2174/0118715249279534240214111155 · Cited by 1
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Agrawal, S. (2017) · Materials and Methods · doi:10.13070/mm.en.7.2226 · Cited by 1
Generating Cell Type-Specific Protein Signatures from Non-symptomatic and Diseased Tissues
Sadick, J. S., Crawford, L. A., Cramer, H. C., Franck, C., Liddelow, S. A., & Darling, E. M. (2020) · Annals of Biomedical Engineering · doi:10.1007/s10439-020-02507-y · Cited by 1
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Xiaodong, P., Murong, Y., Jingjing, X., Pan, Q., Menghao, Y., Jing, X., Lang, C., Ruijie, L., Qinlin, L., Chen, Z., et al. (2020) · Annals of Alzheimer s and Dementia Care · doi:10.17352/aadc.000009 · Cited by 1
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Raleigh, S. M., & Cullen, T. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820682-9.00014-1 · Cited by 1
Wendt, J. A., Considine, C., & Коган, М. И. (2021) · Springer eBooks · doi:10.1007/978-3-030-81758-9_9 · Cited by 1
Valdés‐Martínez, O. H., Garcia-Luna, S., Oceguera-Palao, L. C., Villarreal-Pineda, L., Sordia-Hernández, L. H., Cortez, B. D. L. F., & Morales-Martínez, F. A. (2023) · The Journal of Prevention of Alzheimer s Disease · doi:10.14283/jpad.2023.4 · Cited by 1
Çelik, S., Russell, J. C., Pestana, C. R., Lee, T.-I., Mukherjee, S., Crane, P. K., Keene, C. D., Bobb, J. F., Kaeberlein, M. R., & Lee, S. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/302737 · Cited by 1
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Xx, Y. (2017) · JBR Journal of Clinical Diagnosis and Research · doi:10.4172/2376-0311.1000e108
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Sharma, S., Kaur, P., Gupta, S., & Sharma, S. (2018) · Advances in medical diagnosis, treatment, and care (AMDTC) book series · doi:10.4018/978-1-5225-5282-6.ch005
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Gorina, Y. V., Lopatina, O. L., Komleva, Y. K., Черных, А. И., & Salmina, A. B. (2018) · Human Physiology · doi:10.1134/s0362119718080042
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Trittschuh, E. H., & Wang, L. L. (2019) · Springer eBooks · doi:10.1007/978-1-4939-8722-1_12
Villalba, A. C., Valencia, J. G., Ramos, C., Cuastumal, A. R., Aguillon, D. F., Aguirre–Acevedo, D. C., Madrigal, L., & Lopera, F. J. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-181013
Sosibo, S. C., Amoako, D. G., Somboro, A. M., Sun, D. D., Ngila, J. C., & Kumalo, H. M. (2019) · Letters in Drug Design & Discovery · doi:10.2174/1570180816666191029142640
Fernandez, F., & Andrews, J. L. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-815854-8.00009-4
Mokhtar, S. H., Alzulfi, R. A., Magram, H. K., & Alasmi, N. M. (2021) · International Journal of Pharmaceutical and Phytopharmacological Research · doi:10.51847/kw2fzdwchs
Levy, S., Guttmann‐Beck, N., & Shweiki, D. (2021) · Journal of Alzheimer s Disease Reports · doi:10.3233/adr-210014
Kenanoğlu, S., Kandemir, N., Akalın, H., Gökçe, N., Göl, M. F., Gültekin, M., Köseoğlu, E., Mirza, M., & Dündar, M. (2022) · Global Medical Genetics · doi:10.1055/s-0042-1743570
Mubeen, H., Masood, A., Zafar, A., Khan, Z. Q., Khan, M. Q., Nisa, A. U., & Naveed, Z. A. (2022) · Research Square · doi:10.21203/rs.3.rs-2060964/v1
Baizer, J. S., & Witelson, S. F. (2023) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2023.1069210
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Sekar, M., Lum, P. T., Bonam, S. R., & Gan, S. H. (2023) · doi:10.1002/9781119113324.ch22
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Metadata
- Authors
- Giri, M., Lü, Y., & Zhang, M.
- Affiliations
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Venue
- Clinical Interventions in Aging
- Publisher
- Informa UK Limited
- Published
- 2016-05
- Volume
- 11
- Pages
- 665
- ISSN
- 1176-9092 (ISSN-L)
- 1178-1998
- PMC
- PMC4876682
- OpenAlex
- W2405825843
- Cited by
- 311
- References
- 201
- Citations by year
- 2026: 10 · 2025: 24 · 2024: 33 · 2023: 33 · 2022: 41 · 2021: 36 · 2020: 41 · 2019: 35 · 2018: 29 · 2017: 21 · 2016: 7
- FWCI
- 3.60
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Clinical Interventions in Aging (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Dove Medical Press (Taylor and Francis Group) (submittedVersion, cc-by-nc)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Keywords
- Alzheimer's disease, genetic risk factors, APP, presenilin 1, presenilin 2, APOE ε4, late-onset Alzheimer's disease, early-onset Alzheimer's disease, genome-wide association study, rare variants, PLD3, TREM2, UNC5C, AKAP9, ADAM10, neuropathology, pathogenesis
- MeSH terms
- Alzheimer Disease, Humans, Mutation, Risk Factors, Amyloid beta-Protein Precursor, Genetic Predisposition to Disease, Apolipoprotein E4, Presenilin-1, Presenilin-2, Genome-Wide Association Study
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