Genes associated with Alzheimer's disease: an overview and current status

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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Meta-Analysis of 74,046 Individuals Identifies 11 New Susceptibility Loci for Alzheimer’s Disease

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Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

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Alzheimer’s disease

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TREM2 Variants in Alzheimer's Disease

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Variant of TREM2 Associated with the Risk of Alzheimer's Disease

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Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

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Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

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Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

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Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

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Role of Genes and Environments for Explaining Alzheimer Disease

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Alzheimer Mechanisms and Therapeutic Strategies

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A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

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The role of apolipoprotein E in Alzheimer's disease

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A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N–terminus of β–amyloid

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Human ApoE isoforms differentially regulate brain amyloid-β peptide clearance

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Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

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The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Aβ protofibril formation

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Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

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The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

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Amyloid Precursor Protein Trafficking, Processing, and Function

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Review Article: Genetics of Alzheimer Disease

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Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta

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Apolipoprotein E in Alzheimer’s disease and other neurological disorders

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Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

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Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the β–amyloid precursor protein gene

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The genetics of Alzheimer disease

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APOLIPOPROTEIN E ALLELES AS RISK FACTORS IN ALZHEIMER'S DISEASE

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Mutations in Two Genes Encoding Different Subunits of a Receptor Signaling Complex Result in an Identical Disease Phenotype

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Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein

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Proteolytic processing and cell biological functions of the amyloid precursor protein

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A functional and structural basis for TCR cross-reactivity in multiple sclerosis

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Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS

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CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology

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Midlife Serum Cholesterol and Increased Risk of Alzheimer’s and Vascular Dementia Three Decades Later

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Isoform-specific binding of apolipoprotein E to beta-amyloid.

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Inconsistencies and Controversies Surrounding the Amyloid Hypothesis of Alzheimer's Disease

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Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE

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A Genome-Wide Association Study Identifies Novel Alleles Associated with Hair Color and Skin Pigmentation

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A Portrait of Alzheimer Secretases--New Features and Familiar Faces

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Apolipoprotein E, Dementia, and Cortical Deposition of β-Amyloid Protein

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Locus‐specific mutation databases for neurodegenerative brain diseases

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Clusterin

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Alzheimer’s Disease Genetics: From the Bench to the Clinic

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What makes a good genetic association study?

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Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease

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Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts

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Increased Steady-State Levels of CUGBP1 in Myotonic Dystrophy 1 Are Due to PKC-Mediated Hyperphosphorylation

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Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ϵ4, and the Risk of Late-Onset Alzheimer Disease in African Americans

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Clusterin: Physiologic and pathophysiologic considerations

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Presenilin clinical mutations can affect γ‐secretase activity by different mechanisms

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Molecular mapping of alzheimer‐type dementia in Down's syndrome

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Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance

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Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

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TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson’s disease

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GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease

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Functional Links Between Aβ Toxicity, Endocytic Trafficking, and Alzheimer’s Disease Risk Factors in Yeast

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Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease

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Using Exome Sequencing to Reveal Mutations in TREM2 Presenting as a Frontotemporal Dementia–like Syndrome Without Bone Involvement

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Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias

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Expression of Novel Alzheimer’s Disease Risk Genes in Control and Alzheimer’s Disease Brains

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Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease

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Fyn inhibition rescues established memory and synapse loss in Alzheimer mice

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Role of complement in neurodegeneration and neuroinflammation

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Coding variants in TREM2 increase risk for Alzheimer's disease

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Alzheimer's Presenilin 1 Mutations Impair Kinesin-Based Axonal Transport

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Apolipoprotein E–dependent accumulation of Alzheimer disease–related lesions begins in middle age

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Association of Brain DNA Methylation in SORL1,ABCA7,HLA-DRB5,SLC24A4, and BIN1 With Pathological Diagnosis of Alzheimer Disease

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The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE

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PICALM modulates autophagy activity and tau accumulation

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Genomic organization of the human amyloid beta-protein precursor gene

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Human APOE Isoform-Dependent Effects on Brain β-Amyloid Levels in PDAPP Transgenic Mice

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Linkage and mutational analysis of familial Alzheimer disease kindreds for the APP gene region.

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Clusterin: A forgotten player in Alzheimer's disease

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TREM2 Variant p.R47H as a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis

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TREM2and Neurodegenerative Disease

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Alzheimer’s disease phenotypes and genotypes associated with mutations in presenilin 2

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Retromer Binds the FANSHY Sorting Motif in SorLA to Regulate Amyloid Precursor Protein Sorting and Processing

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The Lipoprotein Receptor LR11 Regulates Amyloid β Production and Amyloid Precursor Protein Traffic in Endosomal Compartments

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Genome-wide association study of Alzheimer's disease

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Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate α-secretase activity

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