The DOI matches its Crossref record; 150 of the 150 references it cites were found in a registry or an index.
Advances in Nanotechnology for Enhancing the Solubility and Bioavailability of Poorly Soluble Drugs
Open accessAbstract
This manuscript offers a comprehensive overview of nanotechnology's impact on the solubility and bioavailability of poorly soluble drugs, with a focus on BCS Class II and IV drugs. We explore various nanoscale drug delivery systems (NDDSs), including lipid-based, polymer-based, nanoemulsions, nanogels, and inorganic carriers. These systems offer improved drug efficacy, targeting, and reduced side effects. Emphasizing the crucial role of nanoparticle size and surface modifications, the review discusses the advancements in NDDSs for enhanced therapeutic outcomes. Challenges such as production cost and safety are acknowledged, yet the potential of NDDSs in transforming drug delivery methods is highlighted. This contribution underscores the importance of nanotechnology in pharmaceutical engineering, suggesting it as a significant advancement for medical applications and patient care.
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Cites
Toxic potential of materials at the nanolevel
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Nano based drug delivery systems: recent developments and future prospects
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PEGylation as a strategy for improving nanoparticle-based drug and gene delivery
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Intestinal mucosal barrier function in health and disease
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Drug Solubility: Importance and Enhancement Techniques
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Metadata
- Authors
- Liu, Y., Liang, Y., Yuhong, J., Xin, P., Han, J. L., Du, Y., Yu, X., Zhu, R., Zhang, M., Chen, W., & Ma, Y.
- Venue
- Drug Design, Development and Therapy
- Publisher
- Informa UK Limited
- Published
- 2024-05
- Volume
- Volume 18
- Pages
- 1469-1495
- ISSN
- 1177-8881 (ISSN-L)
- OpenAlex
- W4396560181
- Cited by
- 365
- References
- 150
- FWCI
- 53.41
- Type
- journal article
- Language
- en
- Open access
- gold
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- Liu, Y., Liang, Y., Yuhong, J., Xin, P., Han, J. L., Du, Y., Yu, X., Zhu, R., Zhang, M., Chen, W., & Ma, Y. (2024). Advances in Nanotechnology for Enhancing the Solubility and Bioavailability of Poorly Soluble Drugs. Drug Design, Development and Therapy. https://doi.org/10.2147/dddt.s447496
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
