The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Preparation, characterization, and potential application of chitosan, chitosan derivatives, and chitosan metal nanoparticles in pharmaceutical drug delivery
Open accessAbstract
Naturally occurring polymers, particularly of the polysaccharide type, have been used pharmaceutically for the delivery of a wide variety of therapeutic agents. Chitosan, the second abundant naturally occurring polysaccharide next to cellulose, is a biocompatible and biodegradable mucoadhesive polymer that has been extensively used in the preparation of micro-as well as nanoparticles. The prepared particles have been exploited as a potential carrier for different therapeutic agents such as peptides, proteins, vaccines, DNA, and drugs for parenteral and nonparenteral administration. Therapeutic agent-loaded chitosan micro- or nanoparticles were found to be more stable, permeable, and bioactive. In this review, we are highlighting the different methods of preparation and characterization of chitosan micro- and nanoparticles, while reviewing the pharmaceutical applications of these particles in drug delivery. Moreover, the roles of chitosan derivatives and chitosan metal nanoparticles in drug delivery have been illustrated.
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Cites
Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach
des Rieux, A., Fievez, V., Garinot, M., Schneider, Y.-J., & Préat, V. (2006) · Journal of Controlled Release · doi:10.1016/j.jconrel.2006.08.013 · Cited by 1,305
Wang, Q., Xie, X., Zhang, X., Zhang, J., & Wang, A. (2010) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2010.01.009 · Cited by 162
Preparation and evaluation of chitosan/carrageenan beads for controlled release of sodium diclofenac
Piyakulawat, P., Praphairaksit, N., Chantarasiri, N., & Muangsin, N. (2007) · AAPS PharmSciTech · doi:10.1208/pt0804097 · Cited by 144
Cited by
Harugade, A., Sherje, A. P., & Pethe, A. (2023) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2023.105634 · Cited by 474
Nanotechnology: An Untapped Resource for Food Packaging
Sharma, C., Dhiman, R., Rokana, N., & Panwar, H. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01735 · Cited by 389
Sharifi-Rad, J., Quispe, C., Butnariu, M., Rotariu, L. S., Sytar, O., Sestito, S., Rapposelli, S., Akram, M., Iqbal, M., Krishna, A., et al. (2021) · Cancer Cell International · doi:10.1186/s12935-021-02025-4 · Cited by 290
Chitosan-Based Nanoparticles of Targeted Drug Delivery System in Breast Cancer Treatment
Herdiana, Y., Wathoni, N., Shamsuddin, S., Joni, I. M., & Muchtaridi, M. (2021) · Polymers · doi:10.3390/polym13111717 · Cited by 196
Nanonization techniques to overcome poor water-solubility with drugs
Da Silva, F. L. O., Marques, M. B. D. F., Kato, K. C., & Carneiro, G. (2020) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2020.1750591 · Cited by 136
Metadata
- Authors
- Ahmed, T., & Aljaeid, B.
- Venue
- Drug Design, Development and Therapy
- Publisher
- Informa UK Limited
- Published
- 2016-01
- Volume
- 10
- Pages
- 483
- ISSN
- 1177-8881 (ISSN-L)
- OpenAlex
- W2266732512
- Cited by
- 705
- References
- 3
- FWCI
- 32.62
- Type
- journal article
- Language
- en
- Open access
- gold
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