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Magnetic nanoparticles for gene and drug delivery
Open accessAbstract
Magnetic nanoparticles for gene and drug delivery Stuart C McBain, Humphrey HP Yiu, Jon DobsonInstitute of Science and Technology in Medicine, Keele University, Thornburrow Drive, Hartshill, Stoke-on-Trent, Staffordshire, ST4 7QB, U.K.Abstract: Investigations of magnetic micro- and nanoparticles for targeted drug delivery began over 30 years ago. Since that time, major progress has been made in particle design and synthesis techniques, however, very few clinical trials have taken place. Here we review advances in magnetic nanoparticle design, in vitro and animal experiments with magnetic nanoparticle-based drug and gene delivery, and clinical trials of drug targeting.Keywords: magnetic nanoparticles, gene delivery, biotechnology
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Wilson, M. W., Kerlan, R. K., Fidelman, N. A., Venook, A. P., LaBerge, J. M., Koda, J., & Gordon, R. L. (2004) · Radiology · doi:10.1148/radiol.2301021493 · Cited by 190
Cited by
Progress in applications of magnetic nanoparticles in biomedicine
Pankhurst, Q. A., Thanh, N. T. K., Jones, S. K., & Dobson, J. (2009) · Journal of Physics D: Applied Physics · doi:10.1088/0022-3727/42/22/224001 · Cited by 1,455
Biological applications of magnetic nanoparticles
Colombo, M., Carregal-Romero, S., Casula, M. F., Gutiérrez, L., Morales, M. P., Böhm, I. B., Heverhagen, J. T., Prosperi, D., & Parak, W. J. (2012) · Chemical Society Reviews · doi:10.1039/c2cs15337h · Cited by 1,315
Passive and Active Drug Targeting: Drug Delivery to Tumors as an Example
Torchilin, V. P. (2010) · Handbook of Experimental Pharmacology · doi:10.1007/978-3-642-00477-3_1 · Cited by 573
New forms of superparamagnetic nanoparticles for biomedical applications
Xu, C., & Sun, S. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.10.008 · Cited by 349
Applications of Cobalt Ferrite Nanoparticles in Biomedical Nanotechnology
Srinivasan, S. Y., Paknikar, K. M., Bodas, D., & Gajbhiye, V. (2018) · Nanomedicine · doi:10.2217/nnm-2017-0379 · Cited by 312
Metadata
- Authors
- Dobson
- Venue
- International Journal of Nanomedicine
- Publisher
- Informa UK Limited
- Published
- 2008-06
- Volume
- 3
- Issue
- 2
- Pages
- 169
- ISSN
- 1176-9114 (ISSN-L)
- 1178-2013
- OpenAlex
- W2167397010
- Cited by
- 755
- References
- 1
- FWCI
- 12.23
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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