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Cited by 701

The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.

Melanoma treatment in review

Open access
Domingues, Beatriz, Lopes, Jose, Soares, Paula, Populo, Helena·2018·ImmunoTargets and Therapy

Abstract

Melanoma represents the most aggressive and the deadliest form of skin cancer. Current therapeutic approaches include surgical resection, chemotherapy, photodynamic therapy, immunotherapy, biochemotherapy, and targeted therapy. The therapeutic strategy can include single agents or combined therapies, depending on the patient's health, stage, and location of the tumor. The efficiency of these treatments can be decreased due to the development of diverse resistance mechanisms. New therapeutic targets have emerged from studies of the genetic profile of melanocytes and from the identification of molecular factors involved in the pathogenesis of the malignant transformation. In this review, we aim to survey therapies approved and under evaluation for melanoma treatment and relevant research on the molecular mechanisms underlying melanomagenesis.

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Metadata

Authors
Domingues, B., Lopes, J., Soares, P., & Populo, H.
Venue
ImmunoTargets and Therapy
Published
2018-06
Volume
Volume 7
Pages
35-49
ISSN
2253-1556 (ISSN-L)
OpenAlex
W2806295244
Cited by
701
References
26
FWCI
24.09
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Melanoma treatment in review. https://app.cochat.ai/papers/10.2147/itt.s134842
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Domingues, B., Lopes, J., Soares, P., & Populo, H. (2018). Melanoma treatment in review. ImmunoTargets and Therapy. https://doi.org/10.2147/itt.s134842

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.