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Cited by 70Ear Surgery and Otitis MediaOtolaryngology and Infectious DiseasesBacterial Infections and Vaccines

Otitis media and sinusitis in children. Role of Branhamella catarrhalis.

Bluestone, Charles D.·1986·Drugs
DOI 10.2165/00003495-198600313-00029
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Abstract

Otitis media and sinusitis are among the most common diseases of childhood and various treatment approaches have been advocated. This review focuses on current experience in Pittsburgh, both in terms of our methods of patient management and the changing aetiology of the underlying diseases. Special reference is made to the role played by Branhamella catarrhalis and the emergence of beta-lactamase-producing strains. Results from recently completed clinical trials would suggest that antibacterial therapy should be administered to children with these infections, to reduce morbidity and prevent the ever-present supportive complications associated with both diseases.

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Crossref · 10.2165/00003495-198600313-00029

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16 of 16 references verified0 citation errors · 0 not checkable

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  • M. catarrhalis is now acknowledged as the third most common cause of otitis media after S. pneumoniae and H. influenzae, and the second most common cause of exacerbations in COPD, accounting for up to 4 million exacerbations per year in the United States alone.

    “Moraxella catarrhalis is a bacteria of increasing importance being now acknowledged as the third most common cause of otitis media (OM), after S. pneumoniae and H. influenzae (Bluestone, 1986; Faden et al., 1994; Kilpi et al., 2001; Dupont et al., 2010) and the second most common cause of exacerbations in COPD, accounting for up to 4 million exacerbations per year in the United States alone (Mur”

    From Secondary bacterial infections associated with influenza pandemics (2017) · cites this paper as Bluestone, 1986

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Authors
Bluestone, C. D.
Affiliations
University of Pittsburgh (US)
Corresponding author
Bluestone, Charles D.
Venue
Drugs
Publisher
Springer Science and Business Media LLC
Published
1986
Volume
31
Issue
Supplement 3
Pages
132-141
ISSN
0012-6667 (ISSN-L)
DOI
10.2165/00003495-198600313-00029
OpenAlex
W2043965523
Cited by
70
References
16
Citations by year
2017: 1 · 2015: 1
FWCI
6.85
Type
journal article
Language
en
Open access
closed
Locations
  • Drugs (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Neurological Disorders and Stroke (NS-16337)
Topics
  • Health Sciences › Medicine › Otorhinolaryngology › Ear Surgery and Otitis Media
  • Health Sciences › Medicine › Infectious Diseases › Otolaryngology and Infectious Diseases
  • Life Sciences › Immunology and Microbiology › Microbiology › Bacterial Infections and Vaccines
Keywords
otitis media, sinusitis, children, Moraxella catarrhalis, beta-lactamase-producing bacteria, antibiotic therapy, etiology, clinical management, clinical trials
MeSH terms
Acute Disease, Amoxicillin, Ampicillin, Child, Chronic Disease, Exudates and Transudates, Humans, Neisseriaceae, Otitis Media, Recurrence, Sinusitis

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