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Immunomodulatory and Antimicrobial Effects of Some Traditional Chinese Medicinal Herbs: A Review
Abstract
The current practice of ingesting phytochemicals to support the immune system or to fight infections is based on centuries-old tradition. We review reports on seven Chinese herbs, (Aloe vera Mill. (Aloaceae), Angelica species (Umbelliferae), Astragalus membranaceus Bunge. (Leguminosae), Ganoderma lucidum (Fr.) Karst. (Ganodermataceae), Panax ginseng C.A Mey. (Araliaceae), Scutellaria species (Lamiaceae) and Zingiber officinale Rosc. (Zingiberaceae) with emphasis to their immunomodulatory and antimicrobial activities. While some of these herbaceous plants have a direct inhibitory effect on microbial organisms, we observe that each plant has at least one compound that selectively modulates cells of the immune system. The successful derivation of pure bioactive compounds from Ganoderma lucidum, ginseng and Zingiber officinale supports the traditional practice of using these plants to stimulate the immune system. As many modern drugs are often patterned after phytochemicals, studying the influence of each compound on immune cells as well as microbes can provide useful insights to the development of potentially useful new pharmacological agents.
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Cited by
Beneficial roles of feed additives as immunostimulants in aquaculture: a review
Dawood, M. A. O., Koshio, S., & Esteban, M. Á. (2018) · Reviews in Aquaculture · doi:10.1111/raq.12209 · Cited by 921
The use of medicinal plants as immunostimulants in aquaculture: A review
Van Hai, N. (2015) · Aquaculture · doi:10.1016/j.aquaculture.2015.03.014 · Cited by 586
Immunostimulatory effects of fucoidan on bone marrow-derived dendritic cells
Kim, M.-H., & Joo, H.-G. (2008) · Immunology Letters · doi:10.1016/j.imlet.2007.10.016 · Cited by 123
Lee, L. S., Andrade, A. S. A., & Flexner, C. (2006) · Clinical Infectious Diseases · doi:10.1086/507894 · Cited by 102
Zhu, Y., Tan, T. L., & Cheang, W. K. (2017) · Chemometrics and Intelligent Laboratory Systems · doi:10.1016/j.chemolab.2017.09.019 · Cited by 13
Metadata
- Authors
- Tan, B., & Vanitha, J.
- Venue
- Current Medicinal Chemistry
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2004-06-01
- Volume
- 11
- Issue
- 11
- Pages
- 1423-1430
- ISSN
- 0929-8673 (ISSN-L)
- OpenAlex
- W2075904898
- Cited by
- 412
- References
- 0
- FWCI
- 18.89
- Type
- journal article
- Language
- en
- Open access
- closed
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