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Anti-Inflammatory Agents from Plants: Progress and Potential
Abstract
The identification of substances that can promote the resolution of inflammation in a way that is homeostatic, modulatory, efficient, and well-tolerated by the body is of fundamental importance. Traditional medicines have long provided front-line pharmacotherapy for many millions of people worldwide. Medicinal extracts are a rich source of therapeutic leads for the pharmaceutical industry. The use of medicinal plant therapies to treat chronic illness, including rheumatoid arthritis (RA) and inflammatory bowel disease (IBD), is thus widespread and on the rise.The aim of this review is to present recent progress in clinical anti-inflammatory studies of plant extracts and compound leads such as green tea polyphenols, curcumin, resveratrol, boswellic acid, and cucurbitacins, among others, against chronic inflammatory diseases, mainly RA and IBD. In this context, the present paper also highlights the most promising experimental data on those plant extracts and pure compounds active in animal models of the aforementioned diseases.
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Citations
Cited by
Curcumin: A Review of Its Effects on Human Health
Hewlings, S., & Kalman, D. (2017) · Foods · doi:10.3390/foods6100092 · Cited by 2,720
The Immunomodulatory and Anti-Inflammatory Role of Polyphenols
Yahfoufi, N., Alsadi, N., Jambi, M., & Matar, C. (2018) · Nutrients · doi:10.3390/nu10111618 · Cited by 1,737
Pulido-Moran, M., Moreno-Fernandez, J., Ramirez-Tortosa, C., & Ramirez-Tortosa, M. (2016) · Molecules · doi:10.3390/molecules21030264 · Cited by 543
Lycopene: Food Sources, Biological Activities, and Human Health Benefits
Khan, U. M., Sevindik, M., Zarrabi, A., Nami, M., Ozdemir, B., Kaplan, D. N., Selamoglu, Z., Hasan, M., Kumar, M., Alshehri, M. M., et al. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/2713511 · Cited by 346
Natural products as reservoirs of novel therapeutic agents
Mushtaq, S., Abbasi, B. H., Uzair, B., & Abbasi, R. (2018) · EXCLI journal · doi:10.17179/excli2018-1174 · Cited by 257
Metadata
- Authors
- Recio, M. C., Andujar, I., & Rios, J. L.
- Venue
- Current Medicinal Chemistry
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2012-04-24
- Volume
- 19
- Issue
- 14
- Pages
- 2088-2103
- ISSN
- 0929-8673 (ISSN-L)
- OpenAlex
- W2127164270
- Cited by
- 210
- References
- 0
- FWCI
- 32.88
- Type
- journal article
- Language
- en
- Open access
- closed
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- Recio, M. C., Andujar, I., & Rios, J. L. (2012). Anti-Inflammatory Agents from Plants: Progress and Potential. Current Medicinal Chemistry. https://doi.org/10.2174/092986712800229069
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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