The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
The Effects of Antipsychotics on the Brain: What Have We Learnt from Structural Imaging of Schizophrenia? – A Systematic Review
Abstract
Despite a large number of neuroimaging studies in schizophrenia reporting subtle brain abnormalities, we do not know to what extent such abnormalities reflect the effects of antipsychotic treatment on brain structure. We therefore systematically reviewed cross-sectional and follow-up structural brain imaging studies of patients with schizophrenia treated with antipsychotics. 30 magnetic resonance imaging (MRI) studies were identified, 24 of them being longitudinal and six cross-sectional structural imaging studies. In patients with schizophrenia treated with antipsychotics, reduced gray matter volume was described, particularly in the frontal and temporal lobes. Structural neuroimaging studies indicate that treatment with typical as well as atypical antipsychotics may affect regional gray matter (GM) volume. In particular, typical antipsychotics led to increased gray matter volume of the basal ganglia, while atypical antipsychotics reversed this effect after switching. Atypical antipsychotics, however, seem to have no effect on basal ganglia structure.
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Cites
Voxel-Based Morphometry—The Methods
Ashburner, J., & Friston, K. J. (2000) · NeuroImage · doi:10.1006/nimg.2000.0582 · Cited by 8,676
A Voxel-Based Morphometric Study of Ageing in 465 Normal Adult Human Brains
Good, C. D., Johnsrude, I. S., Ashburner, J., Henson, R. N. A., Friston, K. J., & Frackowiak, R. S. J. (2001) · NeuroImage · doi:10.1006/nimg.2001.0786 · Cited by 4,561
A review of MRI findings in schizophrenia
Shenton, M. E., Dickey, C. C., Frumin, M., & McCarley, R. W. (2001) · Schizophrenia Research · doi:10.1016/s0920-9964(01)00163-3 · Cited by 2,346
Pariante, C. M., Dazzan, P., Danese, A., Morgan, K. D., Brudaglio, F., Morgan, C., Fearon, P., Orr, K., Hutchinson, G., Pantelis, C., et al. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300766 · Cited by 152
Mathalon, D. H., Sullivan, E. V., Lim, K. O., & Pfefferbaum, A. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.2.148
Cited by
Dysconnectivity in schizophrenia: where are we now?
Pettersson-Yeo, W., Allen, P., Benetti, S., McGuire, P., & Mechelli, A. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.11.004 · Cited by 712
Self-citationFusar-Poli, P., Smieskova, R., Kempton, M. J., Ho, B. C., Andreasen, N. C., & Borgwardt, S. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.06.001 · Cited by 512
Self-citationKoutsouleris, N., Davatzikos, C., Borgwardt, S., Gaser, C., Bottlender, R., Frodl, T., Falkai, P., Riecher-Rossler, A., Moller, H.-J., Reiser, M., et al. (2014) · Schizophrenia Bulletin · doi:10.1093/schbul/sbt142 · Cited by 448
Self-citationSystematic meta-review and quality assessment of the structural brain alterations in schizophrenia
Shepherd, A. M., Laurens, K. R., Matheson, S. L., Carr, V. J., & Green, M. J. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.12.015 · Cited by 412
Abnormal asymmetries in subcortical brain volume in schizophrenia
COCORO, Okada, N., Fukunaga, M., Yamashita, F., Koshiyama, D., Yamamori, H., Ohi, K., Yasuda, Y., Fujimoto, M., Watanabe, Y., et al. (2016) · Molecular Psychiatry · doi:10.1038/mp.2015.209 · Cited by 369
Metadata
- Authors
- Smieskova, R., Fusar-Poli, P., Allen, P., Bendfeldt, K., Stieglitz, R., Drewe, J., Radue, E., McGuire, P., Riecher-Rossler, A., & Borgwardt, S.
- Venue
- Current Pharmaceutical Design
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2009-08-01
- Volume
- 15
- Issue
- 22
- Pages
- 2535-2549
- ISSN
- 1381-6128 (ISSN-L)
- OpenAlex
- W2097019351
- Cited by
- 204
- References
- 5
- FWCI
- 3.69
- Type
- journal article
- Language
- en
- Open access
- closed
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- Smieskova, R., Fusar-Poli, P., Allen, P., Bendfeldt, K., Stieglitz, R., Drewe, J., Radue, E., McGuire, P., Riecher-Rossler, A., & Borgwardt, S. (2009). The Effects of Antipsychotics on the Brain: What Have We Learnt from Structural Imaging of Schizophrenia? – A Systematic Review. Current Pharmaceutical Design. https://doi.org/10.2174/138161209788957456
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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