Cytokine Signaling Modulates Blood-Brain Barrier Function

Structure and function of the blood–brain barrier

Abbott, N. J., Patabendige, A. A. K., Dolman, D. E. M., Yusof, S. R., & Begley, D. J. (2010) · Neurobiology of Disease · doi:10.1016/j.nbd.2009.07.030 · Cited by 5,185

THE BIOCHEMISTRY OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG RESISTANCE

Endicott, J. A., & Ling, V. (1989) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.58.070189.001033 · Cited by 2,071

Transport of brain-derived neurotrophic factor across the blood–brain barrier

Pan, W., Banks, W. A., Fasold, M. B., Bluth, J., & Kastin, A. J. (1998) · Neuropharmacology · doi:10.1016/s0028-3908(98)00141-5 · Cited by 1,354

Revitalizing membrane rafts: new tools and insights

Simons, K., & Gerl, M. J. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2977 · Cited by 1,268

Leptin enters the brain by a saturable system independent of insulin

Banks, W. A., Kastin, A. J., Huang, W., Jaspan, J. B., & Maness, L. M. (1996) · Peptides · doi:10.1016/0196-9781(96)00025-3 · Cited by 1,222

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

Guglielmo, G. M. D., Roy, C. L., Goodfellow, A. F., & Wrana, J. L. (2003) · Nature Cell Biology · doi:10.1038/ncb975 · Cited by 1,152

Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice.

Vaisse, C., Halaas, J. L., Horvath, C. M., Darnell, J. E., Stoffel, M., & Friedman, J. M. (1996) · Nature Genetics · doi:10.1038/ng0996-95 · Cited by 1,086

Physiological response to long-term peripheral and central leptin infusion in lean and obese mice.

Halaas, J. L., Boozer, C., Blair-West, J., Fidahusein, N., Denton, D. A., & Friedman, J. M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.16.8878 · Cited by 1,033

Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation.

Bunone, G., Briand, P.-A., Miksicek, R. J., & Picard, D. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00571.x · Cited by 985

Blood–brain Barrier: Structural Components and Function Under Physiologic and Pathologic Conditions

Persidsky, Y., Ramirez, S. H., Haorah, J., & Kanmogne, G. D. (2006) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-006-9025-3 · Cited by 922

Modulation of gene expression on a transcriptome-wide level following human neural stem cell transplantation in aged mouse stroke brains

Hamblin, M. H., Murad, R., Yin, J., Vallim, G., & Lee, J. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113913 · Cited by 28

Peripheral-to-central immune communication at the area postrema glial-barrier following bleomycin-induced sterile lung injury in adult rats

Litvin, D. G., Denstaedt, S. J., Borkowski, L. F., Nichols, N. L., Dick, T. E., Smith, C. B., & Jacono, F. J. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2020.02.006 · Cited by 23

Involvement of Testosterone Signaling in the Integrity of the Neurovascular Unit in the Male: Review of Evidence, Contradictions, and Hypothesis

Ahmadpour, D., & Grange‐Messent, V. (2020) · Neuroendocrinology · doi:10.1159/000509218 · Cited by 22

Determination of Cytokines and Oxidative Stress Biomarkers in Cognitive Impairment Induced by Methylmalonic Acidemia

Li, Q., Jin, H., Liu, Y., Rong, Y., Yang, T., Nie, X., & Song, W. (2021) · NeuroImmunoModulation · doi:10.1159/000511590 · Cited by 24

Electroacupuncture Alleviates Neuroinflammation by Inhibiting the HMGB1 Signaling Pathway in Rats with Sepsis-Associated Encephalopathy

Xin, Y., Wang, J., Chu, T., Zhou, Y., Liu, C., & Xu, A. (2022) · Brain Sciences · doi:10.3390/brainsci12121732 · Cited by 27

Direct and indirect pro-inflammatory cytokine response resulting from TC-83 infection of glial cells

Keck, F., Kortchak, S., Bakovic, A., Roberts, B., Agrawal, N., & Narayanan, A. (2018) · Virulence · doi:10.1080/21505594.2018.1509668 · Cited by 23

The Neuro-Immuno-Senescence Integrative Model (NISIM) on the Negative Association Between Parasympathetic Activity and Cellular Senescence

Ask, T. F., Lugo, R. G., & Sütterlin, S. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00726 · Cited by 23

Lipopolysaccharide exacerbates chronic restraint stress-induced neurobehavioral deficits: Mechanisms by redox imbalance, ASK1-related apoptosis, autophagic dysregulation

Kwatra, M., Ahmed, S., Gangipangi, V. K., Panda, S. R., Gupta, N., Shantanu, P. A., Gawali, B., & Naidu, V. G. M. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.10.021 · Cited by 22

Immune responses to Tilapia lake virus infection: what we know and what we don’t know

Kembou-Ringert, J. E., Steinhagen, D., Thompson, K. D., Daly, J. M., & Adamek, M. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1240094 · Cited by 22

Evaluation of role of telmisartan in combination with 5-fluorouracil in gastric cancer cachexia

Sukumaran, S., Patel, H. J., & Patel, B. M. (2016) · Life Sciences · doi:10.1016/j.lfs.2016.04.029 · Cited by 22

The effects of a maternal advanced glycation end product-rich diet on somatic features, reflex ontogeny and metabolic parameters of offspring mice

Csongová, M., Gurecká, R., Koborová, I., Celec, P., Renczés, E., Uličná, O., Somoza, V., & Šebeková, K. (2018) · Food & Function · doi:10.1039/c8fo00183a · Cited by 21

Sleep deprivation-induced shifts in gut microbiota: Implications for neurological disorders

Wankhede, N. L., Kale, M. B., Kyada, A., Rekha, M. M., Chaudhary, K., Naidu, K. S., Rahangdale, S. R., Shende, P. V., Taksande, B. G., Khalid, M., et al. (2024) · Neuroscience · doi:10.1016/j.neuroscience.2024.11.070 · Cited by 21

Traumatic events and mental health: The amplifying effects of pre-trauma systemic inflammation

Schrock, J. M., McDade, T. W., Carrico, A. W., D’Aquila, R. T., & Mustanski, B. S. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.08.208 · Cited by 22

A Panax quinquefolius-Based Preparation Prevents the Impact of 5-FU on Activity/Exploration Behaviors and Not on Cognitive Functions Mitigating Gut Microbiota and Inflammation in Mice

Parment, R., Dubois, M., Desrues, L., Mutel, A., Dembélé, K.-P., Belin, N., Tron, L., Guérin, C., Coëffier, M., Compère, V., et al. (2022) · Cancers · doi:10.3390/cancers14184403 · Cited by 20

Altered Function and Expression of ABC Transporters at the Blood–Brain Barrier and Increased Brain Distribution of Phenobarbital in Acute Liver Failure Mice

Liu, L., Miao, M., Chen, Y., Wang, Z., Sun, B., & Liu, X. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00190 · Cited by 20

Anti-Cytokine Therapy to Attenuate Ischemic-Reperfusion Associated Brain Injury in the Perinatal Period

Disdier, C., Chen, X.-D. F., Kim, J.-E., Threlkeld, S. W., & Stonestreet, B. (2018) · Brain Science · doi:10.3390/brainsci8060101 · Cited by 20

Microglial-targeting induced by intranasal linalool during neurological protection postischemia

Barrera-Sandoval, Á. M., Osorio, E., & Cardona‐Gómez, G. P. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.172420 · Cited by 19

Colibactin in avian pathogenic Escherichia coli contributes to the development of meningitis in a mouse model

Wang, P., Zhang, J., Chen, Y., Zhong, H., Wang, H., Li, J., Zhu, G., Xia, P., Cui, L., Li, J., et al. (2021) · Virulence · doi:10.1080/21505594.2021.1972538 · Cited by 19

Evaluating the Role of IL-1β in Transmigration of Triple Negative Breast Cancer Cells Across the Brain Endothelium

Motallebnejad, P., Rajesh, V. V., & Azarin, S. M. (2021) · Cellular and Molecular Bioengineering · doi:10.1007/s12195-021-00710-y · Cited by 20

Bi-Directional Relationship Between Autophagy and Inflammasomes in Neurodegenerative Disorders

Panda, C., & Mahapatra, R. K. (2022) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-021-01184-2 · Cited by 20

Microbes and Mental Illness: Past, Present, and Future

Bransfield, R. C., Mao, C., & Greenberg, R. (2023) · Healthcare · doi:10.3390/healthcare12010083 · Cited by 23

Vancomycin Is Protective in a Neonatal Mouse Model ofStaphylococcus epidermidis-Potentiated Hypoxic-Ischemic Brain Injury

Lai, J. C. Y., Svedin, P., Ek, C. J., Mottahedin, A., Wang, X., Levy, O., Currie, A. J., Strunk, T., & Mallard, C. E. (2019) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02003-19 · Cited by 19

Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain

Singh, D. P., Nimker, C., Paliwal, P. K., & Bansal, A. (2015) · The Journal of Physiological Sciences · doi:10.1007/s12576-015-0429-9 · Cited by 18

Opioid Modulation of the Gut–Brain Axis in Opioid-Associated ComorbiditiesPreprint

Zhang, L., & Roy, S. (2020) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a040485 · Cited by 18

Peripheral Immune System Adaptations and Motivation for Alcohol in Non-Dependent Problem Drinkers

Milivojevic, V., Ansell, E. B., Simpson, C. A., Siedlarz, K. M., Sinha, R., & Fox, H. C. (2017) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13317 · Cited by 19

Acute and Persistent Alterations of Cerebellar Inflammatory Networks and Glial Activation in a Rat Model of Pediatric Mild Traumatic Brain Injury

Fraunberger, E. A., DeJesus, P., Zanier, E. R., Shutt, T. E., & Esser, M. J. (2019) · Journal of Neurotrauma · doi:10.1089/neu.2019.6714 · Cited by 19

A Predictive Model of Vaccine Reactogenicity Using Data from an In Vitro Human Innate Immunity Assay System

Pullen, R. H., Sassano, E. R., Agrawal, P., Escobar, J., Chehtane, M., Schanen, B. C., Drake, D. R., Luna, E., & Brennan, R. (2024) · The Journal of Immunology · doi:10.4049/jimmunol.2300185 · Cited by 16

Blood-based bioenergetic profiling is related to differences in brain morphology in African Americans with Type 2 diabetes

Mahapatra, G., Smith, S. C., Hughes, T. M., Wagner, B., Maldjian, J. A., Freedman, B. I., & Molina, A. J. A. (2018) · Clinical Science · doi:10.1042/cs20180690 · Cited by 16

Microbiota-Gut-Brain Axis and Antidepressant Treatment

Lachmansingh, D. A., Lavelle, A., Cryan, J. F., & Clarke, G. A. (2023) · Current topics in behavioral neurosciences · doi:10.1007/7854_2023_449 · Cited by 17

A Logic Model of Neuronal-Glial Interaction Suggests Altered Homeostatic Regulation in the Perpetuation of Neuroinflammation

Craddock, T. J. A., Michalovicz, L. T., Kelly, K. A., Rice, M. A., Miller, D. B., Klimas, N. G., Morris, M., O'Callaghan, J. P., & Broderick, G. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00336 · Cited by 15

Increased sleep fragmentation in experimental autoimmune encephalomyelitis

He, J., Wang, Y., Kastin, A. J., & Pan, W. (2014) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2014.02.005 · Cited by 15

NEUROPROTECTIVE IMMUNITY: Leukaemia Inhibitory Factor (LIF) as guardian of brain health

Metcalfe, S. M. (2019) · Medicine in Drug Discovery · doi:10.1016/j.medidd.2019.100006 · Cited by 15

Stress‐related suppression of peripheral cytokines predicts future relapse in alcohol‐dependent individuals with and without subclinical depression

Fox, H. C., Milivojevic, V., MacDougall, A., LaVallee, H., Simpson, C. A., Angarita, G. A., & Sinha, R. (2019) · Addiction Biology · doi:10.1111/adb.12832 · Cited by 15

Saturable Leptin Transport Across the BBB Persists in EAE Mice

Hsuchou, H., Mishra, P. K., Kastin, A. J., Wu, X., Wang, Y., Ouyang, S., & Pan, W. (2013) · Journal of Molecular Neuroscience · doi:10.1007/s12031-013-9993-8 · Cited by 14

Effect of Central Injection of Neostigmine on the Bacterial Endotoxin Induced Suppression of GnRH/LH Secretion in Ewes during the Follicular Phase of the Estrous Cycle

Herman, A. P., Skipor, J., Krawczyńska, A., Bochenek, J., Wojtulewicz, K., Pawlina, B., Antushevich, H., Herman, A., & Tomaszewska-Zaremba, D. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20184598 · Cited by 14

Multiple Sclerosis: LIFNano-CD4 for Trojan Horse Delivery of the Neuro-Protective Biologic “LIF” Into the Brain: Preclinical Proof of Concept

de la Flor, R., Robertson, J., Shevchenko, R., Alavijeh, M. S., Bickerton, S., Fahmy, T. M., & Metcalfe, S. M. (2021) · Frontiers in Medical Technology · doi:10.3389/fmedt.2021.640569 · Cited by 14

Repurposing the antipsychotic drug amisulpride for targeting synovial fibroblast activation in arthritis

Papadopoulou, D., Roumelioti, F., Tzaferis, C., Chouvardas, P., Pedersen, A.-K., Charalampous, F., Christodoulou‐Vafeiadou, E., Ntari, L., Karagianni, N., Denis, M. C., et al. (2023) · JCI Insight · doi:10.1172/jci.insight.165024 · Cited by 13

Peptides at the blood brain barrier: Knowing me knowing you

Davis, T. P., Abbruscato, T. J., & Egleton, R. D. (2015) · Peptides · doi:10.1016/j.peptides.2015.04.020 · Cited by 13

Barriers to T Cell Functionality in the Glioblastoma Microenvironment

Nader, N. E., Frederico, S. C., Miller, T. A., Huq, S., Zhang, X., Kohanbash, G., & Hadjipanayis, C. G. (2024) · Cancers · doi:10.3390/cancers16193273 · Cited by 13

Viral Infection of the Central Nervous System Exacerbates Interleukin-10 Receptor Deficiency-Mediated Colitis in SJL Mice

Uhde, A., Herder, V., Khan, M. A., Ciurkiewicz, M., Schaudien, D., Teich, R., Floess, S., Baumgärtner, W., Huehn, J., & Beineke, A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0161883 · Cited by 13

High-density lipoprotein reduces microglia activation and protects against experimental autoimmune encephalomyelitis in mice

Hong, S., Niu, M. Y., Meng, D.-M., Li, A., Dong, Q., Zhang, J., Tian, X., Lu, S., & Wang, Y. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.108566 · Cited by 12

MMP-3 Knockout Induces Global Transcriptional Changes and Reduces Cerebral Infarction in Both Male and Female Models of Ischemic Stroke

Hamblin, M. H., Boese, A. C., Murad, R., & Lee, J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25137383 · Cited by 11

Neurotoxicities After CAR T-Cell Immunotherapy

Gust, J., Ceppi, F., & Turtle, C. J. (2019) · Elsevier eBooks · doi:10.1016/b978-0-323-66181-2.00007-x · Cited by 10

The Effects of Neurotrophins and the Neuropeptides VIP and PACAP on HIV-1 Infection: Histories with Opposite Ends

Souza, T. M. L., Temerozo, J. R., Giestal‐de‐Araujo, E., & Bou‐Habib, D. C. (2014) · NeuroImmunoModulation · doi:10.1159/000357434 · Cited by 13

Effects of Toxoplasma gondii infection on the function and integrity of human cerebrovascular endothelial cells and the influence of verapamil treatment in vitro

Harun, M. S. R., Marsh, V. L., Elsaied, N. A., Webb, K. F., & Elsheikha, H. M. (2020) · Brain Research · doi:10.1016/j.brainres.2020.147002 · Cited by 11

Gut-Microbiome Implications in Opioid Use Disorder and Related Behaviors

Herlihy, B., & Roy, S. (2022) · Advances in Drug and Alcohol Research · doi:10.3389/adar.2022.10311 · Cited by 10

Neostigmine Attenuates Proinflammatory Cytokine Expression in Preoptic Area but Not Choroid Plexus during Lipopolysaccharide-Induced Systemic Inflammation

Herman, A. P., Tomaszewska-Zaremba, D., Kowalewska, M., Szczepkowska, A., Oleszkiewicz, M., Krawczyńska, A., Wójcik, M., Antushevich, H., & Skipor, J. (2018) · Mediators of Inflammation · doi:10.1155/2018/9150207 · Cited by 10

Influence of dietary habits on depression among patients with rheumatoid arthritis: A cross-sectional study using KURAMA cohort database

Minamino, H., Katsushima, M., Hashimoto, M., Fujita, Y., Torii, M., Ikeda, K., Isomura, N., Oguri, Y., Yamamoto, W., Watanabe, R., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0255526 · Cited by 10

Acute Effect of Caffeine on the Synthesis of Pro-Inflammatory Cytokines in the Hypothalamus and Choroid Plexus during Endotoxin-Induced Inflammation in a Female Sheep Model

Szczepkowska, A., Wójcik, M., Tomaszewska-Zaremba, D., Antushevich, H., Krawczyńska, A., Wiechetek, W., Skipor, J., & Herman, A. P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222413237 · Cited by 10

Inflammation as a mediator of stress-related psychiatric disorders

Flux, M. C., & Lowry, C. A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-85654-6.00052-6 · Cited by 10

Metabolic and immune dysfunctions in post-traumatic stress disorder: what can we learn from animal models?

Lushchak, O. V., Orrù, M., Strilbytska, O. M., Berezovskyi, V., Cherkas, A., Storey, K. B., & Bayliak, M. M. (2023) · EXCLI journal · doi:10.17179/excli2023-6391 · Cited by 12

Does Obstructive sleep apnea mediate the risk of cognitive impairment by expanding the perivascular space?

Ke, S., Luo, T., Ding, Y., Tang, C.-J., Jie, Z., Shen, J. Z., Wu, D., & Du, Y. (2025) · Sleep And Breathing · doi:10.1007/s11325-025-03291-6 · Cited by 7

LIF and multiple sclerosis: One protein with two healing properties

Metcalfe, S. M. (2018) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2018.01.018 · Cited by 7

Acute memory deficits in chemotherapy-treated adults

Lindner, O. C., Mayes, A. R., McCabe, M. G., & Talmi, D. (2017) · Memory · doi:10.1080/09658211.2017.1300667 · Cited by 7

Anxiety and depression in adult-onset Still’s disease patients and associations with health-related quality of life

Chi, H., Jin, H., Wang, Z., Feng, T., Zeng, T., Shi, H., Wu, X., Wan, L., Teng, J., Sun, Y., et al. (2020) · Clinical Rheumatology · doi:10.1007/s10067-020-05094-4 · Cited by 7

The Neuroimmune Role of Intestinal Microbiota in the Pathogenesis of Cardiovascular Disease

Suslov, A. V., Chairkina, E., Davidovna, S. M., Suslova, I. S., Khotina, V. A., Kirichenko, T. V., & Postnov, A. Y. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10091995 · Cited by 7

Impact of COVID-19 pneumonia on pulmonary vascular volume

Fahrni, G., Rocha, A. C., Gudmundsson, L., Pozzessere, C., Qanadli, S. D., & Rotzinger, D. C. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2023.1117151 · Cited by 6

Specimen type validation and establishment of normal cytokine reference intervals in cerebrospinal fluid

Martins, T. B., Hill, H. R., & Peterson, L. K. (2024) · Journal of Immunological Methods · doi:10.1016/j.jim.2024.113681 · Cited by 6

Type-1-to-type-2 transition of brain microvascular pericytes induced by cytokines and disease-associated proteins: Role in neuroinflammation and blood-brain barrier disruption

Bohannon, D. G., Wellman, L. L., Kaul, M., Galkina, E., Guo, M., Datta, P. K., & Kim, W. (2024) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x241296270 · Cited by 7

Maternal nematode infection upregulates expression of Th2/Treg and diapedesis related genes in the neonatal brain

Ahdab, N. E., Haque, M., Madogwe, E., Koski, K. G., & Scott, M. E. (2021) · Scientific Reports · doi:10.1038/s41598-021-01510-0 · Cited by 6

Binary classification model of machine learning detected altered gut integrity in controlled-cortical impact model of traumatic brain injury

Rahman, Z., Pasam, T., Kr, R., & Dandekar, M. P. (2022) · International Journal of Neuroscience · doi:10.1080/00207454.2022.2095271 · Cited by 6

Electroencephalographic findings post‐COVID‐19 vaccination: A systematic review of case reports and case series

Fazlollahi, A., Zahmatyar, M., Shamekh, A., Motamedi, A., Seyedi, F., Seyedmirzaei, H., Mousavi, S. E., Nejadghaderi, S. A., Sullman, M. J. M., Kolahi, A., et al. (2023) · Reviews in Medical Virology · doi:10.1002/rmv.2484 · Cited by 6

Alzheimer’s disease: Toward the rational design of an effective vaccine.

Marciani, D. J. (2015) · Revista de Neuro-Psiquiatría · doi:10.20453/rnp.2015.2572 · Cited by 6

How Hormones Influence Composition and Physiological Function of the Brain-Blood Barrier

Hampl, R., Bičı́ková, M., & SOSVOROVÁ, L. (2015) · Physiological Research · doi:10.33549/physiolres.933110 · Cited by 6

Association between dementia risk and ulcerative colitis, with and without colectomy: a Swedish population-based register study

Garcia‐Argibay, M., Hiyoshi, A., & Montgomery, S. (2023) · BMJ Open · doi:10.1136/bmjopen-2023-074110 · Cited by 5

Schizophrenia Patient Shows a Rare Interleukin 15 Receptor alpha Variant Disrupting Signal Transduction

Pan, Y., Wang, Z., Zhang, G., Guo, J., Zhu, X., Zhou, J., Zhang, Z., Sun, Z., Yang, J., Kastin, A. J., et al. (2019) · Current Molecular Medicine · doi:10.2174/1566524019666190617172054 · Cited by 5

From blood to brain through BBB and astrocytic signaling

Pan, W. (2015) · Peptides · doi:10.1016/j.peptides.2015.06.003 · Cited by 5

Systemic Sympathoexcitation Was Associated with Paraventricular Hypothalamic Phosphorylation of Synaptic CaMKIIα and MAPK/ErK

Ogundele, O. M., Rosa, F. A., Dharmakumar, R., Lee, C. C., & Francis, J. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00447 · Cited by 5

Aberrant brain functional network in COPD patients with cognitive impairment: clinical manifestations, mechanisms and therapeutic strategies

He, J., Han, X., Tan, Y.-S., Yao, Z., Dong, Y.-L., & Feng, C. (2025) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03651-9 · Cited by 4

Inflammatory Biomarkers and Neurotransmitter Perturbations in Delirium

Maldonado, J. R. (2020) · Springer eBooks · doi:10.1007/978-3-030-25751-4_10 · Cited by 6

The association between interleukin‐8 levels and the development of withdrawal symptoms during methamphetamine abstinence

Feng, L., He, W., Lin, S., Ruan, Y., Yuan, C., Qiu, H., Ren, W., & He, J. (2020) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.2736 · Cited by 4

A novel co-culture model for investigation of the effects of LPS-induced macrophage-derived cytokines on brain endothelial cells

Yang, J., Li, Y., Bhalla, A., Maienschein‐Cline, M., & Fukuchi, K.-I. (2023) · PLoS ONE · doi:10.1371/journal.pone.0288497 · Cited by 5

Study on the pharmacokinetics and brain tissue distribution of eight anti-inflammatory active components in normal and neuroinflammatory rats orally administered with extract of Tinospora sinensis (Lour.) Merr. using the UPLC-MS/MS method

Chen, L., Lu, L., Xu, G., Jiang, Z., Guo, Q., Huang, F., Yan, W., Zhang, H., Wu, Y., Xie, Y., et al. (2025) · Fitoterapia · doi:10.1016/j.fitote.2025.106564 · Cited by 3

Potential connections between senescence and chemobrain: An early overview of literature

Melhem, N. Y., Qutifan, S., Alsalem, M., & Saleh, T. (2025) · Ageing Research Reviews · doi:10.1016/j.arr.2025.102896 · Cited by 4

Comparative analysis of the uptake of the H+/OC antiporter substrate oxycodone across and into brain endothelial and parenchymal cells with in vitro–in vivo extrapolation

Bällgren, F., Svane, N., Ginosyan, A., Pedersen, A. B. V., Li, S., Mahajan, J., Nielsen, M. S., Brodin, B., & Loryan, I. (2025) · Fluids and Barriers of the CNS · doi:10.1186/s12987-025-00726-w · Cited by 3

From evolutionary advantage to global epidemic: the multisystemic impact of obesity on metabolic health and the potential of bergamot (Citrus bergamia)

Sormani, L. E., Palacio, T. L. N., & Corrêa, C. R. (2025) · Nutrire · doi:10.1186/s41110-025-00394-8 · Cited by 3

Microbiota-Gut-Brain Axis in Neurological Disorders

Sundaram, S., Ponnambath, D. K., & Nair, S. S. (2022) · Springer eBooks · doi:10.1007/978-981-16-7672-7_7 · Cited by 4

Are hemoglobin-derived peptides involved in the neuropsychiatric symptoms caused by SARS-CoV-2 infection?

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