Fungal ATP-Binding Cassette (ABC) Transporters in Drug Resistance & Detoxification

Antibody drug conjugate: the “biological missile” for targeted cancer therapy

Fu, Z., Li, S., Han, S., Shi, C., & Zhang, Y. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-00947-7 · Cited by 1,643

Efflux-Mediated Antifungal Drug Resistance

Cannon, R. D., Lamping, E., Holmes, A. R., Niimi, K., Baret, P. V., Keniya, M. V., Tanabe, K., Niimi, M., Goffeau, A., & Monk, B. C. (2009) · Clinical Microbiology Reviews · doi:10.1128/cmr.00051-08 · Cited by 608

Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?

Dobson, P. D., & Kell, D. B. (2008) · Nature Reviews Drug Discovery · doi:10.1038/nrd2438 · Cited by 475

Fungicide-Driven Evolution and Molecular Basis of Multidrug Resistance in Field Populations of the Grey Mould Fungus Botrytis cinerea

Kretschmer, M., Leroch, M., Mosbach, A., Walker, A. S., Fillinger, S., Mernke, D., Schoonbeek, H., Pradier, J., Leroux, P., Waard, M. A. D., et al. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000696 · Cited by 420

A nuclear receptor-like pathway regulating multidrug resistance in fungi

Thakur, J. K., Arthanari, H., Yang, F., Pan, S.-J., Fan, X., Breger, J., Frueh, D. P., Gulshan, K., Li, D. K., Mylonakis, E., et al. (2008) · Nature · doi:10.1038/nature06836 · Cited by 343

Stress, drugs, and evolution: the role of cellular signaling in fungal drug resistance.

Cowen, L. E., & Steinbach, W. J. (2008) · Eukaryotic Cell · doi:10.1128/ec.00041-08 · Cited by 285

Efflux in Fungi: La Pièce de Résistance

Coleman, J. J., & Mylonakis, E. E. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000486 · Cited by 236

ABC Transporters in Saccharomyces cerevisiae and Their Interactors: New Technology Advances the Biology of the ABCC (MRP) Subfamily

Paumi, C. M., Chuk, M., Snider, J. D., Štagljar, I., & Michaelis, S. (2009) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00020-09 · Cited by 194

Azole resistance mechanisms in Aspergillus: update and recent advances

Pérez‐Cantero, A., López‐Fernández, L., Guarro, J., & Capilla, J. (2019) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2019.09.011 · Cited by 185

ABC Transporter Cdr1p Contributes More than Cdr2p Does to Fluconazole Efflux in Fluconazole-Resistant Candida albicans Clinical Isolates

Holmes, A. R., Lin, Y.-H., Niimi, K., Lamping, E., Keniya, M. V., Niimi, M., Tanabe, K., Monk, B. C., & Cannon, R. D. (2008) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00463-08 · Cited by 160

Interaction of pesticides with p-glycoprotein and other ABC proteins: A survey of the possible importance to insecticide, herbicide and fungicide resistance

Buss, D. S., & Callaghan, A. (2007) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2007.12.001 · Cited by 152

Understanding polyspecificity of multidrug ABC transporters: closing in on the gaps in ABCB1

Gutmann, D. A. P., Ward, A. B., Urbatsch, I. L., Chang, G. A., & van Veen, H. W. (2009) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2009.07.009 · Cited by 152

SalK/SalR, a Two-Component Signal Transduction System, Is Essential for Full Virulence of Highly Invasive Streptococcus suis Serotype 2

Li, M., Wang, C., Feng, Y., et al. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002080 · Cited by 148

A mutation of the H-loop selectively affects rhodamine transport by the yeast multidrug ABC transporter Pdr5

Ernst, R., Kueppers, P., Klein, C. M., Schwarzmueller, T., Kuchler, K., & Schmitt, L. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0800191105 · Cited by 146

A specialized ABC efflux transporter G c ABC ‐ G 1 confers monoterpene resistance to G rosmannia clavigera , a bark beetle‐associated fungal pathogen of pine trees

Wang, Y., Lim, L., DiGuistini, S., et al. (2012) · New Phytologist · doi:10.1111/nph.12063 · Cited by 124

Regulations of sugar transporters: insights from yeast

Horák, J. (2013) · Current Genetics · doi:10.1007/s00294-013-0388-8 · Cited by 113

Essential Letters in the Fungal Alphabet

Perlin, M. H., Andrews, J. M., & Toh, S. S. (2014) · Advances in genetics · doi:10.1016/b978-0-12-800271-1.00004-4 · Cited by 110

Flo11p, drug efflux pumps, and the extracellular matrix cooperate to form biofilm yeast colonies

Váchová, L., Šťovíček, V., Hlaváček, O., Chernyavskiy, O., S̆tĕpánek, L., Kubínová, L., & Palková, Z. (2011) · The Journal of Cell Biology · doi:10.1083/jcb.201103129 · Cited by 100

Fungal Drug Response and Antimicrobial Resistance

Osset-Trénor, P., Pascual‐Ahuir, A., & Proft, M. (2023) · Journal of Fungi · doi:10.3390/jof9050565 · Cited by 108

AtMRP6/AtABCC6, an ATP-Binding Cassette transporter gene expressed during early steps of seedling development and up-regulated by cadmium in Arabidopsis thaliana

Gaillard, S., Jacquet, H., Vavasseur, A., et al. (2008) · BMC Plant Biology · doi:10.1186/1471-2229-8-22 · Cited by 99

ABC transporter functions as a pacemaker for sequestration of plant glucosides in leaf beetles

Strauß, A., Peters, S., Boland, W., & Burse, A. (2013) · eLife · doi:10.7554/elife.01096 · Cited by 90

Genome-wide identification of ATP binding cassette (ABC) transporter and heavy metal associated (HMA) gene families in flax (Linum usitatissimum L.)

Khan, N., You, F. M., Datla, R., Ravichandran, S., Jia, B., & Cloutier, S. (2020) · BMC Genomics · doi:10.1186/s12864-020-07121-9 · Cited by 91

Proteomic analysis and identification of copper stress-regulated proteins in the marine alga Scytosiphon gracilis (Phaeophyceae)

Porcia, L. C., Moenne, A., Gaillard, F., et al. (2009) · Aquatic Toxicology · doi:10.1016/j.aquatox.2009.10.007 · Cited by 89

An Ultra High-Throughput, Whole-Animal Screen for Small Molecule Modulators of a Specific Genetic Pathway in Caenorhabditis elegans

Leung, C. K., Wang, Y., Malany, S., Deonarine, A., Nguyen, K. H., Vasile, S., & Choe, K. P. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062166 · Cited by 75

Tetrandrine achieved plasma concentrations capable of reversing MDR in vitro and had no apparent effect on doxorubicin pharmacokinetics in mice

Dai, C.-L., Xiong, H.-Y., Tang, L.-F., Zhang, X., Liang, Y.-J., Zeng, M., Chen, L., Wang, X., & Fu, L. (2007) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-007-0420-0 · Cited by 63

Nuclear receptor-like transcription factors in fungiPreprint

Näär, A. M., & Thakur, J. K. (2009) · Genes & Development · doi:10.1101/gad.1743009 · Cited by 59

Protein‐facilitated transport of hydrophobic molecules across the yeast plasma membrane

Claus, S., Jezierska, S., & Bogaert, I. V. (2019) · FEBS Letters · doi:10.1002/1873-3468.13469 · Cited by 59

Is there a serious risk of resistance development to azoles among fungi due to the widespread use and long-term application of azole antifungals in medicine?

Hof, H. (2008) · Drug Resistance Updates · doi:10.1016/j.drup.2008.01.001 · Cited by 60

Multiplex assay for condition-dependent changes in protein–protein interactions

Schlecht, U., Miranda, M., Suresh, S., Davis, R. W., & St.Onge, R. P. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1204952109 · Cited by 58

Antifungal mechanism of 1-nonanol against Aspergillus flavus growth revealed by metabolomic analyses

Zhang, S., Qin, Y.-L., Li, S., et al. (2021) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-021-11581-8 · Cited by 59

Pathogenesis and Antifungal Drug Resistance of the Human Fungal Pathogen Candida glabrata

Tscherner, M., Schwarzmüller, T., & Kuchler, K. (2011) · Pharmaceuticals · doi:10.3390/ph4010169 · Cited by 60

Membrane-active Compounds Activate the Transcription Factors Pdr1 and Pdr3 Connecting Pleiotropic Drug Resistance and Membrane Lipid Homeostasis inSaccharomyces cerevisiae

Schüller, C., Mamnun, Y. M., Wolfger, H., Rockwell, N. C., Thorner, J. W., & Kuchler, K. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-06-0610 · Cited by 55

Multidrug Resistance in Mammals and Fungi—From MDR to PDR: A Rocky Road from Atomic Structures to Transport Mechanisms

Khunweeraphong, N., & Kuchler, K. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094806 · Cited by 56

OsPDR20 is an ABCG metal transporter regulating cadmium accumulation in rice

He, L., Li, C., Sun, D., & Yang, Z. M. (2022) · Journal of Environmental Sciences · doi:10.1016/j.jes.2022.09.021 · Cited by 52

Toward understanding the mechanism of action of the yeast multidrug resistance transporter Pdr5p: A molecular modeling study

Rutledge, R. M., Esser, L., Ma, J., & Xia, D. (2010) · Journal of Structural Biology · doi:10.1016/j.jsb.2010.10.012 · Cited by 48

The Anticancer Ruthenium Complex KP1019 Induces DNA Damage, Leading to Cell Cycle Delay and Cell Death in Saccharomyces cerevisiae

Stevens, S. K., Strehle, A. P., Miller, R. L., et al. (2012) · Molecular Pharmacology · doi:10.1124/mol.112.079657 · Cited by 45

Unique structure and regulation of the nematode detoxification gene regulator, SKN-1: implications to understanding and controlling drug resistance

Choe, K. P., Leung, C. K., & Miyamoto, M. M. (2012) · Drug Metabolism Reviews · doi:10.3109/03602532.2012.684799 · Cited by 47

Evidence for the Role of Calcineurin in Morphogenesis and Calcium Homeostasis during Mycelium-to-Yeast Dimorphism of Paracoccidioides brasiliensis

de Campos, C. B. L., Benedette, J. P. T. D., Morais, F. V., Ovalle, R., & Nóbrega, M. P. (2008) · Eukaryotic Cell · doi:10.1128/ec.00110-08 · Cited by 42

Next-generation antifungal drugs: Mechanisms, efficacy, and clinical prospects

Lu, X., Zhou, J., Ming, Y., Wang, Y., He, R., Li, Y., Feng, L., Zeng, B., Du, Y., & Wang, C. (2025) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2025.06.013 · Cited by 50

Host-Pathogen Interactions Mediated by MDR Transporters in Fungi: As Pleiotropic as it Gets!

Cavalheiro, M., Pais, P., Galocha, M., & Teixeira, M. C. (2018) · Genes · doi:10.3390/genes9070332 · Cited by 44

Differential gene expression in Pyropia columbina (Bangiales, Rhodophyta) under natural hydration and desiccation conditions

Porcia, L. C., López‐Cristoffanini, C., Lovazzano, C., et al. (2013) · Latin American Journal of Aquatic Research · doi:10.3856/vol41-issue5-fulltext-13 · Cited by 39

Transcriptome of an A rmillaria root disease pathogen reveals candidate genes involved in host substrate utilization at the host–pathogen interface

Ross‐Davis, A. L., Stewart, J. E., Hanna, J. W., et al. (2013) · Forest Pathology · doi:10.1111/efp.12056 · Cited by 39

Improve the production of d -limonene by regulating the mevalonate pathway of Saccharomyces cerevisiae during alcoholic beverage fermentation

Hu, Z., Li, H., Weng, Y., Li, P., Zhang, C., & Xiao, D. (2020) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/s10295-020-02329-w · Cited by 37

Lead, cadmium and nickel removal efficiency of white‐rot fungus Phlebia brevispora

Sharma, K., Giri, R., & Sharma, R. K. (2020) · Letters in Applied Microbiology · doi:10.1111/lam.13372 · Cited by 34

PdMfs1, a major facilitator superfamily transporter from Penicillium digitatum, is partially involved in the imazalil-resistance and pathogenicity

Wang, J.-Y. (2012) · African Journal of Microbiology Research · doi:10.5897/ajmr11.1045 · Cited by 32

Transcriptome analysis shows differential gene expression in the saprotrophic to parasitic transition of Pochonia chlamydosporia

Rosso, L. C., Finetti-Sialer, M. M., Finetti-Sialer, M. M., et al. (2011) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-011-3282-7 · Cited by 31

Evolutionary Trajectories of Entomopathogenic Fungi ABC Transporters

Baral, B. (2017) · Advances in genetics · doi:10.1016/bs.adgen.2017.07.002 · Cited by 31

Metabolomic analyses revealed multifaceted effects of hexanal on Aspergillus flavus growth

Li, S., Zhang, S., Lv, Y., Zhai, H.-C., Li, N., Hu, Y., & Cai, J.-P. (2021) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-021-11293-z · Cited by 26

A simple yeast-based system for analyzing inhibitor resistance in the human cancer drug targets Hsp90α/β

Millson, S. H., Prodromou, C., & Piper, P. W. (2010) · Biochemical Pharmacology · doi:10.1016/j.bcp.2010.01.031 · Cited by 25

Advancing Functional Genetics Through Agrobacterium -Mediated Insertional Mutagenesis and CRISPR/Cas9 in the Commensal and Pathogenic Yeast Malassezia

Ianiri, G., Dagotto, G., Sun, S., & Heitman, J. (2019) · Genetics · doi:10.1534/genetics.119.302329 · Cited by 25

Transcriptional profiling of Saccharomyces cerevisiae exposed to propolis

de Castro, P. A., Savoldi, M., Bonatto, D., Malavazi, I., Goldman, M. H. S., Berretta, A. A., & Goldman, G. H. (2012) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-12-194 · Cited by 24

Enhancement of β-Caryophyllene Biosynthesis in Saccharomyces cerevisiae via Synergistic Evolution of β-Caryophyllene Synthase and Engineering the Chassis

Lu, S., Deng, H. X., Zhou, C., Du, Z., Guo, X., Cheng, Y., & He, X. (2023) · ACS Synthetic Biology · doi:10.1021/acssynbio.3c00024 · Cited by 23

Will resistance in fungi emerge on a scale similar to that seen in bacteria?

Hof, H. (2008) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-007-0451-9 · Cited by 22

The transport activity of the multidrug ABC transporter BmrA does not require a wide separation of the nucleotide-binding domains

Cesare, M. D., Kaplan, E., Rendon, J., Gerbaud, G., Valimehr, S., Gobet, A., Ngo, T.-A. T., Chaptal, V., Falson, P., Martinho, M., et al. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.105546 · Cited by 18

Blocking drug efflux mechanisms facilitate genome engineering process in hypercellulolytic fungus, Penicillium funiculosum NCIM1228

Randhawa, A., Pasari, N., Sinha, T., Gupta, M., Nair, A. M., Ogunyewo, O. A., Verma, S., Verma, P. K., & Yazdani, S. S. (2021) · Biotechnology for Biofuels · doi:10.1186/s13068-021-01883-4 · Cited by 21

Metabolomic and Transcriptome Analysis of the Inhibitory Effects of Bacillus subtilis Strain Z-14 against Fusarium oxysporum Causing Vascular Wilt Diseases in Cucumber

Liu, Z., Fan, C., Xiao, J., Sun, S., Gao, T., Zhu, B., & Zhang, D. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c07539 · Cited by 20

Xenobiotic Efflux in Bacteria and Fungi: A Genomics Update

Barabote, R. D., Thekkiniath, J., Strauss, R. E., Vediyappan, G., Fralick, J. A., & Francisco, M. J. S. (2011) · Advances in enzymology and related areas of molecular biology/Advances in enzymology and related subjects · doi:10.1002/9780470920541.ch6 · Cited by 22

Genome sequencing of Cladophialophora exuberans, a novel candidate for bioremediation of hydrocarbon and heavy metal polluted habitats

da Silva, N. M., Reis, G. F., Costa, F. D. F., Grisolia, M. E., Geraldo, M. R., Lustosa, B. P. R., Lima, B. J. F. D. S., Weiss, V. A., de Souza, E. M., Li, R., et al. (2023) · Fungal Biology · doi:10.1016/j.funbio.2023.03.003 · Cited by 19

Metabolic Profiles and Free Radical Scavenging Activity of Cordyceps bassiana Fruiting Bodies According to Developmental Stage

Hyun, S. H., Lee, S.-Y., Sung, G., Kim, S. H., & Choi, H. (2013) · PLoS ONE · doi:10.1371/journal.pone.0073065 · Cited by 19

Identification of in vivo induced protein antigens of Salmonella enterica serovar Typhi during human infection

Hu, Y., Cong, Y., Li, S., et al. (2009) · Science in China Series C Life Sciences · doi:10.1007/s11427-009-0127-z · Cited by 18

Role of Ectopic Gene Conversion in the Evolution of a Candida krusei Pleiotropic Drug Resistance Transporter Family

Lamping, E., Zhu, J., Niimi, M., & Cannon, R. D. (2017) · Genetics · doi:10.1534/genetics.116.194811 · Cited by 19

SWI/SNF and the histone chaperone Rtt106 drive expression of the Pleiotropic Drug Resistance network genes

Nikolov, V. N., Malavia, D., & Kubota, T. (2022) · Nature Communications · doi:10.1038/s41467-022-29591-z · Cited by 16

Fungal mechanisms of intracellular survival: what can we learn from bacterial pathogens?

Stuckey, P. V., & Santiago-Tirado, F. H. (2023) · Infection and Immunity · doi:10.1128/iai.00434-22 · Cited by 21

Antibody–drug conjugate: a newly developed biological missile for tumor treatment

Tang, Z., Xie, Y., & Zeng, Y. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1688057 · Cited by 18

Proteolysis-targeting chimeras in biotherapeutics: Current trends and future applications

Li, Q., Zhou, L., Qin, S., Huang, Z., Li, B., Li, B., Yang, M., Nice, E. C., Zhu, H., & Huang, C. (2023) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2023.115447 · Cited by 17

Biocidal and antibiofilm activities of arginine-based surfactants against Candida isolates

Fait, M. E., Grillo, P. D., Garrote, G. L., Prieto, E. D., Vázquez, R. F., Saparrat, M. C. N., & Morcelle, S. R. (2023) · Amino Acids · doi:10.1007/s00726-023-03296-z · Cited by 15

Identification and characterization of a drug‐sensitive strain enables puromycin‐based translational assays in Saccharomyces cerevisiae

Cary, G. A., Yoon, S. H., Garmendia‐Torres, C., Wang, K., Hays, M., Ludlow, C. L., Goodlett, D. R., & Dudley, A. M. (2014) · Yeast · doi:10.1002/yea.3007 · Cited by 15

CgHog1 controls the adaptation to both sorbitol and fludioxonil in Colletotrichum gloeosporioides

Li, Y., He, P., Tian, C., & Wang, Y. (2019) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2019.103289 · Cited by 14

Analysis of the Phialocephala subalpina Transcriptome during Colonization of Its Host Plant Picea abies

Reininger, V., & Schlegel, M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0150591 · Cited by 13

Discovery of ML358, a Selective Small Molecule Inhibitor of the SKN-1 Pathway Involved in Drug Detoxification and Resistance in Nematodes.

Peddibhotla, S., Fontaine, P., Leung, C., Maloney, P., Hershberger, P., Wang, Y., Bousquet, M. S., Luesch, H., Mangravita-Novo, A., Pinkerton, A., et al. (2015) · ACS Chemical Biology · doi:10.1021/acschembio.5b00304 · Cited by 12

Cell detoxification of secondary metabolites by P4-ATPase-mediated vesicle transport

Li, Y., Ren, H. J., Wang, F., et al. (2023) · eLife · doi:10.7554/elife.79179 · Cited by 11

ABCC Transporter Gene MoABC-R1 Is Associated with Pyraclostrobin Tolerance in Magnaporthe oryzae

Hu, P., Liu, Y., Zhu, X., & Kang, H. (2023) · Journal of Fungi · doi:10.3390/jof9090917 · Cited by 10

ABC Transporters and Their Function at the Plasma Membrane

Knöller, A. S., & Murphy, A. S. (2010) · Plant cell monographs · doi:10.1007/978-3-642-13431-9_16 · Cited by 11

P-Glycoprotein–Mediated Efflux Reduces the In Vivo Efficacy of a Therapeutic Targeting the Gastrointestinal Parasite Cryptosporidium

Arnold, S. L. M., Choi, R., Hulverson, M. A., et al. (2019) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiz269 · Cited by 11

A critical role of farnesol in the modulation of Amphotericin B and Aureobasidin A antifungal drug susceptibility

Mahendrarajan, V., & Bari, V. K. (2022) · Mycology: An International Journal on Fungal Biology · doi:10.1080/21501203.2022.2138599 · Cited by 12

A High‐Throughput Screen for Chemical Inhibitors of Exocytic Transport in Yeast

Zhang, L., Nebane, N. M., Wennerberg, K., Li, Y., Neubauer, V., Hobrath, J. V., McKellip, S. N., Rasmussen, L. A., Shindo, N., Sosa, M. I., et al. (2010) · ChemBioChem · doi:10.1002/cbic.200900681 · Cited by 11

Discovery of Pyrazolone Carbothioamide Derivatives as Inhibitors of the Pdr1-KIX Interaction for Combinational Treatment of Azole-Resistant Candidiasis

Wang, Q., Tu, J., Yang, W., Liang, T., Liu, N., & Sheng, C. (2023) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.3c00488 · Cited by 12

Curcumin potentiates the fungicidal effect of dodecanol by inhibiting drug efflux in wild‐type budding yeast

Yamawaki, C., Oyama, M., Yamaguchi, Y., Ogita, A., Tanaka, T., & Fujita, K. (2018) · Letters in Applied Microbiology · doi:10.1111/lam.13083 · Cited by 10

Genome mining the black-yeast Aureobasidium pullulans NRRL 62031 for biotechnological traits

Xiao, D., Driller, M., Stein, K., et al. (2025) · BMC Genomics · doi:10.1186/s12864-025-11395-2 · Cited by 9

The fungicide fludioxonil antagonizes fluconazole activity in the human fungal pathogen Candida albicans

Heintz‐Buschart, A., Burakowska, A., & Bilitewski, U. (2012) · Journal of Medical Microbiology · doi:10.1099/jmm.0.050963-0 · Cited by 9

Searching for the Mechanism that Mediates Mefenoxam-Acquired Resistance in Phytophthora infestans and How It Is Regulated

González‐Tobón, J., Childers, R. R., Rodríguez, A., Fry, W., Myers, K. L., Thompson, J. R., Restrepo, S., & Danies, G. (2021) · Phytopathology · doi:10.1094/phyto-07-21-0280-r · Cited by 7

The RNA helicase Ski2 in the fungal pathogen Cryptococcus neoformans highlights key roles in azoles resistance and stress tolerance

Li, C., Ma, X., Ma, L., Zhen, S., Na, Y., Zhang, P., & Zhu, X. (2022) · Medical Mycology · doi:10.1093/mmy/myac083 · Cited by 7

Dual RNA-Seq Profiling Unveils Mycoparasitic Activities of Trichoderma atroviride against Haploid Armillaria ostoyae in Antagonistic Interaction Assays

Chen, L., Champramary, S., Sahu, N., et al. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.04626-22 · Cited by 7

Navigating fungal infections and antifungal stewardship: drug resistance, susceptibility testing, therapeutic drug monitoring and future directions

Gupta, A., Mann, A., Ravi, S. P., & Wang, T. (2023) · Italian Journal of Dermatology and Venereology · doi:10.23736/s2784-8671.23.07694-6 · Cited by 8

Comparing Fungal Sensitivity to Isothiocyanate Products on Different Botrytis spp.

Ruiz, V. C., Aleu, J., & Collado, I. G. (2024) · Plants · doi:10.3390/plants13060756 · Cited by 7

Drug transporters in spermatogenesis

Mruk, D. D., & Cheng, C. Y. (2012) · Spermatogenesis · doi:10.4161/spmg.20507 · Cited by 7

Enhanced Detection of Estrogen-like Compounds by Genetically Engineered Yeast Sensor Strains

Abu-Rmailah, N., Moscovici, L., Riegraf, C., et al. (2024) · Biosensors · doi:10.3390/bios14040193 · Cited by 6

A novel polyamide SL-A92 as a potential fungal resistance blocker: synthesis and bioactivities in Candida albicans

Zhu, S.-L., Jiang, Z., Gao, P., Qiu, Y., Wang, L., Jiang, Y., & Zhang, D. (2010) · Acta Pharmacologica Sinica · doi:10.1038/aps.2010.59 · Cited by 6

A collection of yeast mutants selectively resistant to ionophores acting on mitochondrial inner membrane

Petrezsélyová, S., Laláková, J., Abelovska, L., Klobučnı́ková, V., & Tomáška, Ľ. (2007) · Mitochondrion · doi:10.1016/j.mito.2007.10.003 · Cited by 6

Dehydrozingerone Exhibits Synergistic Antifungal Activities in Combination with Dodecanol against Budding Yeast via the Restriction of Multidrug Resistance

Yamawaki, C., Yamaguchi, Y., Ogita, A., Tanaka, T., & Fujita, K. (2018) · Planta Medica International Open · doi:10.1055/a-0757-7991 · Cited by 6

Dehydrozingerone enhances the fungicidal activity of glabridin againstSaccharomyces cerevisiaeandCandida albicans

Yamano, S., Tsukuda, Y., Mizuhara, N., Yamaguchi, Y., Ogita, A., & Fujita, K. (2023) · Letters in Applied Microbiology · doi:10.1093/lambio/ovad040 · Cited by 5

Unravelling Drug Resistance in Candida Species: Genetic, Biofilm, Transcriptional, and Epigenetic Perspectives

Kumar, A., Francis, A., Hans, S., & Thakur, A. (2024) · Springer eBooks · doi:10.1007/978-981-97-4909-6_8 · Cited by 6

Pyrrocidines A and B demonstrate synergistic inhibition of Fusarium verticillioides growth

Lofton, L. W., Read, Q. D., Hamilton, H. L., et al. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1480920 · Cited by 3

Transcriptome analysis of Aspergillus oryzae RIB40 under chemical stress reveals mechanisms of adaptation to fungistatic compounds of lignocellulosic side streams

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Shi, W., Zhao, R., Zhu, J.-Q., Wan, X., Wang, L., Li, H., & Qin, S. (2023) · BMC Microbiology · doi:10.1186/s12866-023-02865-2 · Cited by 3

Changes in intestinal microbiota, immunity and metabolism caused by mixed Lactiplantibacillus plantarum and Bacillus subtilis-fermented feed in Bamei pigs

Wang, L., Chen, J., Zhang, J., Xu, F., Luo, X., Pang, H., Zhang, M., Duan, Y., Cai, Y., Wu, G., et al. (2024) · Chemical and Biological Technologies in Agriculture · doi:10.1186/s40538-024-00593-x · Cited by 3

ABC and MFS Transporters: A reason for Antifungal drug resistance

Neelabh, D., & Singh, K. (2018) · Archives of Biotechnology and Biomedicine · doi:10.29328/journal.abb.1001009 · Cited by 4

Evolutionary origin and sequence signatures of the heterodimeric ABCG5 / ABCG8 transporter

Pei, J., & Cong, Q. (2022) · Protein Science · doi:10.1002/pro.4297 · Cited by 3

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Gaetano, G. V. D., Lentini, G., Famà, A., Coppolino, F., & Beninati, C. (2023) · Antibiotics · doi:10.3390/antibiotics12060965 · Cited by 97

The role of RND-type efflux pumps in multidrug-resistant mutants of Klebsiella pneumoniae

Ni, R. T., Onishi, M., Mizusawa, M., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-67820-x · Cited by 84

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