The DOI matches its Crossref record.
The Role of Microbiota and Probiotics in Stress-Induced Gastrointestinal Damage
Abstract
Stress has a major impact on gut physiology and may affect the clinical course of gastro-intestinal diseases. In this review, we focus on the interaction between commensal gut microbiota and intestinal mucosa during stress and discuss the possibilities to counteract the deleterious effects of stress with probiotics. Normally, commensal microbes and their hosts benefit from a symbiotic relationship. Stress does, however, reduce the number of Lactobacilli, while on the contrary, an increased growth, epithelial adherence and mucosal uptake of gram-negative pathogens, e.g. E. coli and Pseudomonas, are seen. Moreover, intestinal bacteria have the ability to sense a stressed host and up-regulate their virulence factors when opportunity knocks. Probiotics are "live microorganisms which, when administered in adequate amounts, confer a health benefit on the host", and mainly represented by Lactic Acid Bacteria. Probiotics can counteract stress-induced changes in intestinal barrier function, visceral sensitivity and gut motility. These effects are strain specific and mediated by direct bacterial-host cell interaction and/or via soluble factors. Mechanisms of action include competition with pathogens for essential nutrients, induction of epithelial heat-shock proteins, restoring of tight junction protein structure, up-regulation of mucin genes, secretion of defensins, and regulation of the NFkappaB signalling pathway. In addition, the reduction of intestinal pain perception was shown to be mediated via cannabinoid receptors. Based on the studies reviewed here there is clearly a rationale for probiotic treatment in patients with stress-related intestinal disorders. We are however far from being able to choose the precise combination of strains or bacterial components for each clinical setting.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Animal models of chronic stress demonstrate altered intestinal physiology and GM composition, with an increased secretory state and permeability (352–355).”
From Signalling cognition: The gut microbiota and hypothalamic-pituitary-adrenal axis (2023) · cites this paper as [355]
In the citing paper
“Recent studies have suggested that GC signaling derives a portion of its effects through gut microbes.21,22”
From Using Corticosteroids to Reshape the Gut Microbiome: Implications for Inflammatory Bowel Diseases (2015) · cites this paper as [21]
Citations
Cited by
Sorted by citations
Items 101–200 of 228
Cinca-Morros, S., & Álvarez‐Herms, J. (2024) · Microorganisms · doi:10.3390/microorganisms12061160 · Cited by 20
“Interventions focused on precise nutrition and probiotic intake [55,71] could be necessary when athletes include heat exposure during their training and competitive routines.”
BackgroundInfluence of Propolis on Intestinal Microflora of Ross Broilers Exposed to Hot Environment
Abdel–Mohsein, H. S. (2014) · Advances in Animal and Veterinary Sciences · doi:10.14737/journal.aavs/2014/2.4.204.211 · Cited by 19
“…increase growth and virulence factor expression in pathogenic bacteria within the lumen and alter host susceptibility to pathogenic bacteria and thus posing a threat to bird's health and food safety (Gaggìa et al., 2011, Keita and So¨derholm, 2010, Bailey et al., 2004 and Lyte & Bailey, 1997).”
BackgroundProbiotics Can Alleviate Cardiopulmonary Bypass-Induced Intestinal Mucosa Damage in Rats
Sun, Y., Cao, H., Song, D., Diao, Y.-G., Zhou, J., & Zhang, T. (2013) · Digestive Diseases and Sciences · doi:10.1007/s10620-012-2546-0 · Cited by 19
“Most studies adopted probiotic supplements to protect the intestinal mucosa after traumatic stress [18–20].”
BackgroundUnderstanding the ADHD-Gut Axis by Metabolic Network Analysis
Taş, E., & Ülgen, K. Ö. (2023) · Metabolites · doi:10.3390/metabo13050592 · Cited by 18
Acupuncture for Parkinson's disease-related constipation: current evidence and perspectives
Zhang, J., Ge, X., Zhang, K., Qi, Y. P., Ren, S., & Zhai, X. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1253874 · Cited by 18
“The gut microbiota can regulate the expression of proteins and genes related to mucosal immunity in the gut, mediate the NF-κB signaling pathway involved in gut mucosal barrier protection, and maintain gut immune regulation and motility (28).”
BackgroundRohmann, N., Geese, T., Nestel, S., Schlicht, K., Geisler, C., Türk, K., Brix, F., Jensen‐Kroll, J., Demetrowitsch, T. J., Bang, C., et al. (2024) · BMC Medicine · doi:10.1186/s12916-024-03709-0 · Cited by 20
“In IBD, stress can be linked to lower abundance of the beneficial genus Lactobacillus [68], and smoking increases the abundance of the genus Prevotella in both Crohn’s disease (CD) patients and healthy individuals [69].”
BackgroundÁlvarez, A., Montaña, A. R., Acuña, S. P. C., et al. (2025) · Fermentation · doi:10.3390/fermentation11070359 · Cited by 17
Liu, S., Wen, D., Feng, C., Yu, C., Gu, Z., Wang, L., Zhang, Z., Li, W., Wu, S., Liu, Y., et al. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1114233 · Cited by 18
“Probiotics counteract stressinduced changes in intestinal barrier function and mucosal inflammation by regulating macrophage cytokines and NF-κB activation (Lutgendorff et al., 2008; Habil et al., 2011).”
BackgroundLin, M., Su, T., Chen, C., Wu, W., Hsu, S., Tseng, T., Liao, S., Hong, C., Yang, H., Liu, C., et al. (2023) · Gut Pathogens · doi:10.1186/s13099-023-00549-w · Cited by 17
“In addition, Bacteroides plays a role in the intestinal immune network by activating intestinal dendritic cells, which help control the overgrowth of pathogenic strains and maintain the integrity of the intestinal epithelial barrier [22, 23].”
BackgroundEffects of Stress on the Mucus-microbial Interactions in the Gut
He, J., Guo, H., Zheng, W., & Yao, W. (2018) · Current Protein and Peptide Science · doi:10.2174/1389203719666180514152406 · Cited by 17
The Role of the Gut Microbiome in Inflammatory Bowel Disease: The Middle East Perspective
El-Sayed, A., Kapila, D., Taha, R. S. I., El-Sayed, S., Mahen, M. R. A., Taha, R., & Alrubaiy, L. (2024) · Journal of Personalized Medicine · doi:10.3390/jpm14060652 · Cited by 17
“, while diets Bacteroidetes inhibit aberrant immune activation and the emergence of inflammatory illnesses like IBD and allergies by interacting with the host immune system [6]. heavy in fat and sugar can cause in fl ammation, dysbiosis, and metabolic disorders [25–27] (Figure 1).”
BackgroundMicrobiome's Universe: Impact on health, disease and cancer treatment
Réthi‐Nagy, Z., & Juhász, S. (2024) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2024.07.002 · Cited by 17
Exercise and Prebiotics Produce Stress Resistance
Mika, A., Rumian, N. L., Loughridge, A. B., & Fleshner, M. (2016) · International review of neurobiology · doi:10.1016/bs.irn.2016.08.004 · Cited by 19
The relationship between gut microbiota and neonatal pathologic jaundice: A pilot case-control study
You, J. J., Qiu, J., Li, G. N., Peng, X. M., Ma, Y., Zhou, C., Fang, S., Huang, R., & Xiao, Z. H. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1122172 · Cited by 14
“Bacteroides thetaiotaomicron is reported to induce the expression of the small proline-rich protein 2A (sprr2A), which is necessary to maintain the epithelial villus desmosomes (Lutgendorff et al., 2008).”
BackgroundProbiotics in Aquaculture - Benefits to the Health, Technological Applications and Safety
Zhou, X., & Wang, Y. (2012) · InTech eBooks · doi:10.5772/29037 · Cited by 14
“…of multiple antimicrobial materials by intestinal Paneth cells through cell-autonomous MyD88-dependent toll-like receptor activation (Vaishnava et al., 2008) and regulate the alterations of permeability related with infections, stress, and inflammatory conditions (Lutgendorff et al., 2008).”
BackgroundDevelopment and Functions of the Infant Gut Microflora: Westernvs. Indian Infants
Bharadia, L., Agrawal, N., & Joshi, N. A. (2020) · International Journal of Pediatrics · doi:10.1155/2020/7586264 · Cited by 14
“Gut commensals employ various mechanisms to offer colonization resistance, including (a) production of antimicrobial substances such as bacteriocins (microbiocidal compounds for killing competitor strains), (b) modification of the pH of the luminal content, and (c) competition for nutrients required by the pathogenic…”
BackgroundRodrigues, M. L., Damasceno, D. Z., Gomes, R. L. M., Sosa, B. D. S., Moro, E. B., Boscolo, W. R., Bittencourt, F., & Signor, A. (2020) · Aquaculture Nutrition · doi:10.1111/anu.13198 · Cited by 17
Early Life Stress Induces Both Acute and Chronic Colonic Barrier Dysfunction
Gareau, M. G., Wine, E., & Sherman, P. M. (2009) · NeoReviews · doi:10.1542/neo.10-4-e191 · Cited by 13
Association Between Non-Suicidal Self-Injury and Gut Microbial Characteristics in Chinese Adolescent
Cai, L.-F., Wang, S., Hou, C., Li, Z., Liao, Y.-J., & Jia, F. (2022) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s360588 · Cited by 11
“Previous studies have shown that lactic acid bacteria are greatly reduced by stress and that the administration of lactic acid bacteria improves stressinduced behavior.(37,38) Another study showed decreased Protococcus, Faecalibacterium, Ruminococcus, Bifidobacterium and Escherichia coli, while accessory bacteria incr…”
ResultLu, G., Zhang, S., Wang, R., Zhang, Z., Wang, W., Wen, Q., Zhang, F., & Li, P. (2023) · Nutrients · doi:10.3390/nu15173704 · Cited by 11
Yin, Y., Feng, W., Chen, X., Chen, J., Wang, G., Xia, L., & Wu, K. (2024) · The Innovation Medicine · doi:10.59717/j.xinn-med.2024.100092 · Cited by 11
Yang, Z., Wu, Y., Liu, X., Zhang, M., Peng, J., & Wei, H. (2022) · Nutrients · doi:10.3390/nu14173485 · Cited by 11
“Early weaning can easily result in an immune stress response in the gut, which in turn can lead to bowel diseases, such as diarrhea, infection, dyspepsia, and malnutrition [3].”
BackgroundShayista, H., Prasad, M. N. N., Raj, S. N., Prasad, A., Satish, S., Ranjini, H. K., Manju, K. G., Ravikumara, Chouhan, R. S., Khohlova, O. Y., et al. (2025) · Medicine in Microecology · doi:10.1016/j.medmic.2025.100122 · Cited by 17
Selection of New Probiotics: The Case of Streptomyces
Hariharan, S., & Dharmaraj, S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-814625-5.00003-0 · Cited by 10
Nguyen, H. T., Hongsrichan, N., Intuyod, K., Pinlaor, P., Yingklang, M., Chaidee, A., Sengthong, C., Pongking, T., DANGTAKOT, R., Banjong, D., et al. (2022) · Bioscience of Microbiota Food and Health · doi:10.12938/bmfh.2021-054 · Cited by 10
“Several probiotic strains of Lactobacillus and Bifidobacterium have beneficial functions, such as the inhibition of intestinal colonisation by pathogenic microorganisms and anti-carcinogenic, anti-diarrhoeal, and immunostimulatory properties [39], as well as the maintenance of tight junctions in intestinal epithelia […”
BackgroundThe Role of Intestinal Microbiota and Probiotics Supplementation in Multiple Sclerosis Management
Hasaniani, N., Rahimi, S. M., Akbari, M., Sadati, F., Pournajaf, A., & Rostami-Mansoor, S. (2024) · Neuroscience · doi:10.1016/j.neuroscience.2024.05.013 · Cited by 12
Segers, C., Mysara, M., Coolkens, A., Baatout, S., Leys, N., Lebeer, S., Verslegers, M., & Mastroleo, F. (2022) · Applied Microbiology · doi:10.3390/applmicrobiol2030049 · Cited by 8
Intestinal bacteria and probiotics: effects on the immune system and impacts on human health
Trejo, F. M., & Sanz, Y. (2013) · Elsevier eBooks · doi:10.1533/9780857095749.3.267 · Cited by 10
Impact of acute stress on the canine gut microbiota
Patel, K. V., Hunt, A. B. G., Fernandez, J. C., Abrams, C., King, T., Watson, P., & Amos, G. C. A. (2024) · Scientific Reports · doi:10.1038/s41598-024-66652-3 · Cited by 10
“As such, it is thought that exposure to stress could modify the commensal gut microbiota composition through driving a reduction in health-associated bacteria and increasing some potentially pathogenic species 11 .”
BackgroundMeng, K., Lin, X., Chen, Y., et al. (2023) · Aquaculture · doi:10.1016/j.aquaculture.2023.739228 · Cited by 8
Prediction of BMI traits in the Chinese population based on the gut metagenome
Liang, Y., Dou, S., Zhao, G., Shen, J., Fu, G., Fu, L., Li, S., Cong, B., & Dong, C. (2023) · Microbial Cell Factories · doi:10.1186/s12934-023-02255-3 · Cited by 8
The Current and Future Role of Drugs and Probiotics in the Management of Inflammatory Bowel Disease
de Souza, M. D. S. S., Barbalho, S. M., Goulart, R. D. Á., & de Carvalho, A. D. C. A. (2015) · Journal of Biosciences and Medicines · doi:10.4236/jbm.2015.38008 · Cited by 7
“) [83] and competitive exclusive by competes with adhesion of pathogens to the intestinal mucosa and makes the colonization of the intestine with beneficial bacteria [84].”
BackgroundBell, R. L., Withers, G. S., Kuypers, F. A., Stehr, W., & Bhargava, A. (2021) · PLoS ONE · doi:10.1371/journal.pone.0246412 · Cited by 7
Ahn, H.-R., Park, D. H., Shin, M., Nguyen, Q. N., Park, J. Y., Kim, D., Kang, K. S., & Lee, H. L. (2022) · Applied Sciences · doi:10.3390/app12146943 · Cited by 7
“Therefore, the diversity and settlement of intestinal microbes in children directly affects their health from infancy to adolescence, and gut microbes play an important long-term role in children [7,8].”
BackgroundCheng, X., Li, S., Huang, C., Yang, Y., Liu, R., Cao, S., Luo, L., & Lu, B. (2026) · Chinese Medicine · doi:10.1186/s13020-025-01311-x · Cited by 7
“This is achieved through the restoration of tight junction protein complexes and the upregulation of mucin gene expression [40].”
Understanding the human gut microbiome: from composition to disease association
Alali, M. A., & Shori, A. B. (2026) · Frontiers in Microbiomes · doi:10.3389/frmbi.2026.1717288 · Cited by 11
Glucocorticoids and the Intestinal Environment
Ünsal, H., & Balkay, M. (2012) · InTech eBooks · doi:10.5772/51977 · Cited by 6
“When the stressful events cause a decrease in beneficial bacteria, they generally increase the pathogenic species within the gut microenvironment [67-69].”
BackgroundKhezri, M. R., Esmaeili, A., & Ghasemnejad‐Berenji, M. (2023) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.3c00418 · Cited by 7
Ross, S. M. (2014) · Holistic Nursing Practice · doi:10.1097/hnp.0000000000000047 · Cited by 6
Prebiotics and Probiotics in Therapy and Prevention of Gastrointestinal Diseases in Children
Salvatore, S., & Vandenplas, Y. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-374938-3.00013-x · Cited by 6
Chen, Q., Wang, Z., Shao, D., & Shi, S. (2022) · World s Poultry Science Journal · doi:10.1080/00439339.2022.2106344 · Cited by 6
“…between probiotics and host intestinal cells induces the expression of a series of genes involved in barrier function and defensin production, which promotes a healthy intestinal environment and improves the growth performance of domestic poultry (Lutgendorff, Akkermans, and Söderholm 2008).”
BackgroundMeimandipour, A., Farjam, A. S., Bejo, M. H., et al. (2011) · South African Journal of Animal Science · doi:10.4314/sajas.v40i4.65248 · Cited by 6
“…stressful experience can disturb the balance of the intestinal microbiota and lead to the excessive growth of pathogens while decreasing the proportion of beneficial bacteria such as lactobacilli and bifidobacteria (Fuller, 1999; Lan et al., 2004; Selig & Patterson, 2004; Lutgendorff et al., 2008).”
Sahoo, D. K., Stewart, T., Lindgreen, E., Patel, B. K., Patel, A., Trivedi, J. N., Parker, V. J., Rudinsky, A. J., Winston, J. A., Bourgois‐Mochel, A., et al. (2025) · Antioxidants · doi:10.3390/antiox14060727 · Cited by 7
The promising path of Oral MOFs: Redefining strategies for gastrointestinal detoxification
Quan, Y., Wu, Y., Wang, K., Ren, H., Zhang, G., Zhao, Y., & Miao, Y. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.217168 · Cited by 6
Exploring the Role of Mentha in Gut Microbiota: A Modern Perspective of an Ancient Herb
Arora, S., & Sharma, A. K. (2023) · Recent Advances in Food Nutrition & Agriculture · doi:10.2174/2772574x14666230411101712 · Cited by 5
Liu, B., Wang, K., Yang, L., et al. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.111562 · Cited by 5
Chapter 2: The composition and role of the microbiota in chickens
Pedroso, A. A., & Lee, M. D. (2014) · Wageningen Academic Publishers eBooks · doi:10.3920/978-90-8686-792-9_2 · Cited by 11
Microbiota in Neuropsychiatry, Part 3
Ross, S. M. (2017) · Holistic Nursing Practice · doi:10.1097/hnp.0000000000000223 · Cited by 5
Obstructive sleep apnea and the gut microbiota – mechanisms and opportunities
Alcock, J. (2025) · Current Opinion in Pulmonary Medicine · doi:10.1097/mcp.0000000000001211 · Cited by 4
Lombardi, V., Martínez, E., Chacón, R., et al. (2009) · BioMed Research International · doi:10.1155/2009/187015 · Cited by 4
“In addition to the effects of probiotics on nonimmunologic gut defense, which is characterized by stabilization of the gut microflora [27, 28], probiotic bacteria have been shown to enhance humoral immune responses and thereby promote the intestine’s immunology barrier [29, 30].”
BackgroundMung bean sprouts yoghurt rich in antioxidants as a functional drink during pandemic
Winarsi, H., Erminawati, E., Andreas, A., & Nuraeni, I. (2022) · Food Research · doi:10.26656/fr.2017.6(1).176 · Cited by 6
Development of an In Vitro Fermentation Model to Culture the Human Distal Gut Microbiota
McDonald, J. A. K. (2013) · The Atrium (University of Guelph) · Cited by 4
Impact of evolution on lifestyle in microbiome
González, A., Fullaondo, A., & Odriozola, A. (2024) · Advances in genetics · doi:10.1016/bs.adgen.2024.02.003 · Cited by 4
Therapeutic Mechanisms of Gut Microbiota and Probiotics in the Management of Mental Disorders
Yadav, M., Kumar, A., & Shandil, A. (2022) · Springer eBooks · doi:10.1007/978-981-16-6760-2_3 · Cited by 3
Microbiome in Human Gastrointestinal Cancers
Coker, O. O., & Yu, J. Q. (2021) · Physiology in health and disease · doi:10.1007/978-3-030-67951-4_2 · Cited by 2
Modulation of Immune System by Probiotics to Protect Against Enteric Disorders
Malago, J., & Koninkx, J. (2011) · Springer eBooks · doi:10.1007/978-94-007-0386-5_12 · Cited by 3
“cus to interfere with bacterial adhesion, colonization and invasion (Freitas et al . 2005; Caballero-Franco et al . 2007), induce secretion of antimicrobial peptides by intestinal Paneth cells (Vaishnava et al . 2008), regulate alterations of intestinal permeability caused by infection, stress, and inflammation ( Lutg…”
BackgroundMetagenomics of the human microbiome
Shestakov, S. (2011) · Biology Bulletin Reviews · doi:10.1134/s2079086411020095 · Cited by 2
Mechanisms of maintenance of intestinal homeostasis by autochthonic microbiota and probiotics
Binek, M., Kizerwetter‐Świda, M., Cisek, A. A., Rzewuska, M., Chrobak‐Chmiel, D., & Gieryńska, M. M. (2016) · Medycyna Weterynaryjna · doi:10.21521/mw.5575 · Cited by 2
Human microbiome and mental health
Padilla, A. B., Sahai, S., Pizarro, R. R. M., Añonuevo, J. J. J., & Enamno, K. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15435-5.00005-0 · Cited by 2
Ross, S. M. (2025) · Holistic Nursing Practice · doi:10.1097/hnp.0000000000000720 · Cited by 2
Ross, S. M. (2025) · Holistic Nursing Practice · doi:10.1097/hnp.0000000000000758 · Cited by 2
Casey, C. L., Hernandez, S. M., Yabsley, M. J., Smith, K. F., & Sánchez, S. (2013) · Journal of Herpetological Medicine and Surgery · doi:10.5818/1529-9651-23.3.74 · Cited by 2
EFFECT OF FEEDS SUPPLEMENTED WITH ASPARAGUS RACEMOSUS ON MILK PRODUCTION OF INDIGENOUS COWS
Garg, N. (2015) · Mintage journal of pharmaceutical and medical sciences · Cited by 2
Gut-Brain Axis and Stress Regulation
Ross, S. M. (2019) · Holistic Nursing Practice · doi:10.1097/hnp.0000000000000346 · Cited by 2
Screening of Lactobacillus Inhibitor Alpha Glucosidase Activity from Nira in Hyperglycemic Mice
Fardhani, R. A., & Aini, A. (2021) · JURNAL BIOLOGI TROPIS · doi:10.29303/jbt.v21i3.2944 · Cited by 2
Dehghani, R., Varzaneh, A. A., Varzaneh, Z. B., et al. (2022) · Journal of Entomological Research · doi:10.5958/0974-4576.2022.00206.7 · Cited by 2
Role of mast cells and probiotics in the regulation of intestinal barrier function
Karlsson, A. (2013) · Linköping University Electronic Press eBooks · doi:10.3384/diss.diva-100770 · Cited by 2
Irritable Bowel Syndrome in Inflammatory Bowel Disease
Ryu, K.-H., & Huh, K. (2010) · Intestinal Research · doi:10.5217/ir.2010.8.2.95 · Cited by 2
“화와 점막의 손상 및 박테리아 생산물의 이동을 발생 시키게 되며, 염증의 증가와 cytokine의 분비가 결국 내장의 과감각화를 초래하게 된다.(87) 물론 CRF의 대”
Correlation Between Gut Microbiota and Chronic Metabolic Diseases
Nawaz, A., Zafar, S., Shahzadi, M., Sharif, M., Saeeda, U. H., Khalid, N. A., & Khan, S. (2024) · Wiley eBooks · doi:10.1002/9781394238071.ch5 · Cited by 4
Gut Microbiota Dynamics in Obesity and Metabolic Regulation
Farhood, A. H., & Shalal, S. H. (2025) · Academia Open · doi:10.21070/acopen.10.2025.12579 · Cited by 1
“Microbial enzymes also play an essential role in degrading complex polysaccharides that humans cannot digest without microbial assistance [56].”
Li, X., Wang, M., Zhang, Z., Zhou, J., Xie, Y., Luo, B., Yu, X., Zhu, Y., & Cai, P. (2025) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2025.12.001 · Cited by 1
Meliha, C., Yılmaz, M., & Mustafa, E. (2026) · Food Science & Nutrition · doi:10.1002/fsn3.71624 · Cited by 1
“Elevated glutathione levels play a significant role in neutralizing free radicals and increasing antioxidant enzyme levels, such as GR and GP x (Lutgendorff et al. 2008).”
Joshi, D., Chauhan, K., Oberoi, H. S., Kumar, D. D., & Taneja, N. K. (2026) · Discover Biotechnology · doi:10.1007/s44340-026-00053-2 · Cited by 1
Alterations in the intestinal microbiota of subjects diagnosed with irritable bowel syndrome
Kassinen, A. (2009) · Cited by 1
Meimandipour, A., Houshmand, M., Kasim, A., et al. (2011) · Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia) · doi:10.5897/ajb.9000210 · Cited by 1
Gut Microbiota Regulation of Cerebral Stroke
Kumar, K., Hema, K., & Tripathi, A. K. (2022) · Nutritional neurosciences · doi:10.1007/978-981-19-4530-4_4 · Cited by 1
Staniak, N., Piaseczna-Spitaleri, E., & Biała, G. (2022) · Postępy Higieny i Medycyny Doświadczalnej · doi:10.2478/ahem-2022-0042 · Cited by 1
Microbioma y enfermedades crónicas
Khouri, L. S., Flores-Andrade, X. A., González, R. S. M., Olmos, I. O. V., Velez-Pintado, M., & Durán, J. P. G. (2022) · Anales Médicos de la Asociación Médica del Centro Médico ABC · doi:10.35366/108781 · Cited by 1
Effects of High-Dose Prednisone on the Gastrointestinal Microbiota of Healthy Dogs
Garrity, S., Whittemore, J. C., Sahoo, D. K., Morgan, S., Lindgreen, E., VanDeWalle, S., Suchodolski, J. S., & Jergens, A. E. (2025) · Veterinary Sciences · doi:10.3390/vetsci12030216 · Cited by 1
Probiotics to Target the Intestinal and Vaginal Microbiota in HIV
Hummelen, R. (2011) · EUR Research Repository (Erasmus University Rotterdam) · Cited by 1
Tarraf, A. A. (2021) · theses.fr (ABES) · doi:10.70675/545bd347z20bcz444cza534z622ac595baf9 · Cited by 1
Studies of barrier function in patients with ulcerative colitis and pouchitis
Persborn, M. (2011) · KTH Publication Database DiVA (KTH Royal Institute of Technology)
The effects of dietary probiotic administration on anxiety and cognition
O’Hagan, C. (2015) · ORCA Online Research @Cardiff (Cardiff University)
Gut Microbiota: Physiology and Relationship with Inflammatory Bowel Disease
Lin, C.-Y., Lin, Y.-J., & Chen, H.-A. (2013) · Open Journal of Endocrine and Metabolic Diseases · doi:10.4236/ojemd.2013.37039
“Moreover, mucosa injury by stress or pathogen assault was shown to be reversed in the presence of probiotics [35].”
BackgroundGirard, S. (2009) · Papyrus : Institutional Repository (Université de Montréal) · doi:10.71781/30754
The impact of host-microbe interactions on murine colonic secretomotor function
Lomasney, K. W. (2014) · Cork Open Research Archive (University College Cork, Ireland)
Nelson, E. (2012) · Swinburne figshare (Swinburne University of Technology) · doi:10.25916/sut.26271883
Inter-Kingdom Signaling Interactions in Enterohemorrhagic Escherichia coli Infections
Bansal, T. (2010) · OakTrust (Texas A&M University Libraries)
Infectious Microecology and Immunology
Diao, H., Cui, G., Chen, J., & Wei, Y. (2014) · Advanced topics in science and technology in China · doi:10.1007/978-3-662-43883-1_3
Green Tea Polyphenols and Gut Health
Theertham Pradyumna, R. A. O., Ōkubo, T., Kapoor, M. P., & Juneja, L. R. (2013) · CRC Press eBooks · doi:10.1201/b14878-14
Stanwicks, L. L. (2021) · ScholarWorks@UMassAmherst (University of Massachusetts Amherst) · doi:10.7275/9054002
Parental and Early Developmental Stress Impact on Neurodevelopmental and Neuropsychiatric Disorders
Nugent, B. M., Chan, J. C., Jašarević, E., & Bale, T. L. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803592-4.00097-3
Medication management in pediatric chronic illness: Should patient anxiety be considered?
Hoogendoorn, C. J. (2016) · CUNY Academic Works (City University of New York)
Calefi, A. S. (2016) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.10.2016.tde-07102016-124200
Microbiota profiling in gastrointestinal health and disease
Tedjo (2018) · Research Publications (Maastricht University) · doi:10.26481/dis.20180301dt
Gut Microbiota, Early Colonization and Factors in its Development that Influence Health
Tungland, B. C. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-814649-1.00001-6
Silva, L. N. D. D. (2013) · Lusophone University Repository
Bhardwaj, A. (2019) · Mspace (University of Manitoba)
Impact of the gut microbiome on physical and mental health
Ţăpescu, M., & Tarcea, M. (2020) · Medic ro · doi:10.26416/med.133.1.2020.2996
The Potential Role of Probiotics in theManagement of Childhood Autism SpectrumDisorders
Critchfield, J. W., van Hemert, S., Ash, M. E., & Ashwood, P. (2014)
Metadata
- Authors
- Lutgendorff, F., Akkermans, L., & Soderholm, J.
- Affiliations
- Linköping University (SE)
- University of Groningen (NL)
- Venue
- Current Molecular Medicine
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2008-06-01
- Volume
- 8
- Issue
- 4
- Pages
- 282-298
- ISSN
- 1566-5240 (ISSN-L)
- OpenAlex
- W2099916508
- Cited by
- 230
- References
- 0
- Citations by year
- 2026: 8 · 2025: 16 · 2024: 16 · 2023: 22 · 2022: 22 · 2021: 11 · 2020: 7 · 2019: 12 · 2018: 10 · 2017: 11 · 2016: 11 · 2015: 13 · 2014: 16 · 2013: 13 · 2012: 5
- FWCI
- 19.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Molecular Medicine (publishedVersion)
- PubMed (publishedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Keywords
- gut microbiota, probiotics, stress, gastrointestinal injury, intestinal barrier function, lactobacilli, Gram-negative pathogens, pathogen virulence factors, lactic acid bacteria, tight junctions, mucin genes, defensins, NF-κB signaling, cannabinoid receptors
- MeSH terms
- Animals, Enteritis, Humans, Immunologic Factors, Intestinal Mucosa, Intestines, Stress, Physiological, Stress, Psychological, Critical Illness, Probiotics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
