The DOI matches its Crossref record; 70 of the 70 references it cites were found in a registry or an index.
Microvascular Complications of Type 2 Diabetes Mellitus
Abstract
Background: Type 2 diabetes mellitus (T2DM) is a chronic, non communicable, multisystem disease that has reached epidemic proportions. Chronic exposure to hyperglycaemia affects the microvasculature, eventually leading to diabetic nephropathy, retinopathy and neuropathy with high impact on the quality of life and overall life expectancy. Sexual dysfunction is an often-overlooked microvascular complication of T2DM, with a complex pathogenesis originating from endothelial dysfunction. Objective: The purpose of this review is to present current definitions, epidemiological data and risk factors for diabetic retinopathy, nephropathy, neuropathy and sexual dysfunction. We also describe the clinical and laboratory evaluation that is mandatory for the diagnosis of these conditions. Method: A comprehensive review of the literature was performed to identify data from clinical studies for the prevalence, risk factors and diagnostic methods of microvascular complications of T2DM. Results: Diabetic nephropathy and retinopathy affect approximately 25% of patients with T2DM; diabetic neuropathy is encountered in almost 50% of the diabetic population, while the prevalence of erectile dysfunction ranges from 35-90% in diabetic men. The duration of T2DM along with glycemic, blood pressure and lipid control are common risk factors for the development of these complications. Criteria for the diagnosis of these conditions are well established, but exclusion of other causes is mandatory. Conclusion: Early detection of microvascular complications associated with T2DM is important, as early intervention leads to better outcomes. However, this requires awareness of their definition, prevalence and diagnostic modalities.
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Glucose control and vascular complications in veterans with type 2 diabetes
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Bioactive compounds in anti-diabetic plants: from herbal medicine to modern drug discovery
Tran, N., Pham, B., & Le, L. (2020) · Biology · doi:10.3390/biology9090252 · Cited by 553
Antioxidant Phytochemicals as Potential Therapy for Diabetic Complications
Akpoveso, O.-O. P., Ubah, E. E., & Obasanmi, G. (2023) · Antioxidants · doi:10.3390/antiox12010123 · Cited by 90
Bioactive Compounds and Diabetes Mellitus: Prospects and Future Challenges
Rahman, M. M., Islam, M. R., Rabbi, F., Islam, M. T., Sultana, S., Ahmed, M., Sehgal, A., Singh, S., Sharma, N., & Behl, T. (2022) · Current Pharmaceutical Design · doi:10.2174/1381612828666220412090808 · Cited by 13
Metadata
- Authors
- Faselis, C., Katsimardou, A., Imprialos, K., Deligkaris, P., Kallistratos, M., & Dimitriadis, K.
- Venue
- Current Vascular Pharmacology
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2020-01-27
- Volume
- 18
- Issue
- 2
- Pages
- 117-124
- ISSN
- 1570-1611 (ISSN-L)
- OpenAlex
- W2943410960
- Cited by
- 549
- References
- 70
- FWCI
- 22.89
- Type
- journal article
- Language
- en
- Open access
- closed
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- Faselis, C., Katsimardou, A., Imprialos, K., Deligkaris, P., Kallistratos, M., & Dimitriadis, K. (2020). Microvascular Complications of Type 2 Diabetes Mellitus. Current Vascular Pharmacology. https://doi.org/10.2174/1570161117666190502103733
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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