Antioxidant Phytochemicals as Potential Therapy for Diabetic Complications
Open accessAbstract
The global prevalence of diabetes continues to increase partly due to rapid urbanization and an increase in the aging population. Consequently, this is associated with a parallel increase in the prevalence of diabetic vascular complications which significantly worsen the burden of diabetes. For these diabetic vascular complications, there is still an unmet need for safe and effective alternative/adjuvant therapeutic interventions. There is also an increasing urge for therapeutic options to come from natural products such as plants. Hyperglycemia-induced oxidative stress is central to the development of diabetes and diabetic complications. Furthermore, oxidative stress-induced inflammation and insulin resistance are central to endothelial damage and the progression of diabetic complications. Human and animal studies have shown that polyphenols could reduce oxidative stress, hyperglycemia, and prevent diabetic complications including diabetic retinopathy, diabetic nephropathy, and diabetic peripheral neuropathy. Part of the therapeutic effects of polyphenols is attributed to their modulatory effect on endogenous antioxidant systems. This review attempts to summarize the established effects of polyphenols on endogenous antioxidant systems from the literature. Moreover, potential therapeutic strategies for harnessing the potential benefits of polyphenols for diabetic vascular complications are also discussed.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Chronic hyperglycemia results in suppressed activity of mTOR associated with AMPK-induced increase in ROS formation and enhanced expression of TXNIP.
“Chronic hyperglycemia results in the suppressed activity of mTOR associated with AMP-activated protein kinase-induced increase in ROS formation and enhanced expression of thioredoxin interacting protein (TXNIP) a potential sensor of glucose and oxidative stress (Akpoveso et al. 2023).”
From Reactive Oxygen Species, Toxicity, Oxidative Stress, and Antioxidants: Chronic Diseases and Aging (2023) · cites this paper as Akpoveso et al. 2023
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
Zinman, B., Wanner, C., Lachin, J. M., Fitchett, D., Bluhmki, E., Hantel, S., Mattheus, M., Devins, T., Johansen, O. E., Woerle, H. J., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1504720 · Cited by 12,315 · see citing works
Sun, H., Saeedi, P., Karuranga, S., Pinkepank, M., Ogurtsova, K., Duncan, B. B., Stein, C., Basit, A., Chan, J. C. N., Mbanya, J. C., et al. (2022) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2021.109119 · Cited by 10,123 · see citing works
Biochemistry and molecular cell biology of diabetic complications
Brownlee, M. (2001) · Nature · doi:10.1038/414813a · Cited by 9,107 · see citing works
(1996) · The Lancet · doi:10.1016/s0140-6736(96)09457-3 · Cited by 6,503 · see citing works
Oxidative stress and diabetic complications
Giacco, F., & Brownlee, M. (2010) · Circulation Research · doi:10.1161/circresaha.110.223545 · Cited by 5,461 · see citing works
The Pathobiology of Diabetic Complications
Brownlee, M. (2005) · Diabetes · doi:10.2337/diabetes.54.6.1615 · Cited by 5,339 · see citing works
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
Sies, H., & Jones, D. P. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-0230-3 · Cited by 5,335 · see citing works
Oxyl radicals, redox-sensitive signalling cascades and antioxidants
Genestra, M. (2007) · Cellular Signalling · doi:10.1016/j.cellsig.2007.04.009 · Cited by 4,930 · see citing works
Pietta, P. (2000) · Journal of Natural Products · doi:10.1021/np9904509 · Cited by 4,881 · see citing works
Lusis, A. J. (2000) · Nature · doi:10.1038/35025203 · Cited by 4,880 · see citing works
Dormandy, J. A., Charbonnel, B., Eckland, D. J., Erdmann, E., Massi-Benedetti, M., Moules, I. K., Skene, A. M., Tan, M. H., Lefèbvre, P. J., Murray, G. D., et al. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67528-9 · Cited by 4,129 · see citing works
O'Donnell, M. J., Xavier, D., Liu, L., Zhang, H., Chin, S. L., Rao-Melacini, P., Rangarajan, S., Islam, S., Pais, P., McQueen, M. J., et al. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60834-3 · Cited by 3,448 · see citing works
Targeting the KEAP1-NRF2 system to prevent kidney disease progression
Nezu, M., Suzuki, N., & Yamamoto, M. (2017) · American Journal of Nephrology · doi:10.1159/000475890 · Cited by 3,447 · see citing works
Cheung, N., Mitchell, P., & Wong, T. Y. (2010) · The Lancet · doi:10.1016/s0140-6736(09)62124-3 · Cited by 3,288 · see citing works
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
Hayes, J. D., & Dinkova‐Kostova, A. T. (2014) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2014.02.002 · Cited by 2,158 · see citing works
The thioredoxin antioxidant system
Lu, J., & Holmgren, A. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.07.036 · Cited by 2,055 · see citing works
Jia, G., Hill, M. A., & Sowers, J. R. (2018) · Circulation Research · doi:10.1161/circresaha.117.311586 · Cited by 1,838 · see citing works
Global trends in diabetes complications: a review of current evidence
Harding, J. L., Pavkov, M. E., Magliano, D. J., Shaw, J. E., & Gregg, E. W. (2018) · Diabetologia · doi:10.1007/s00125-018-4711-2 · Cited by 1,674 · see citing works
Diabetes mellitus and oxidative stress—A concise review
Asmat, U., Abad, K., & Ismail, K. (2016) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2015.03.013 · Cited by 1,570 · see citing works
Roles of vascular oxidative stress and nitric oxide in the pathogenesis of atherosclerosis
Förstermann, U., Xia, N., & Li, H. (2017) · Circulation Research · doi:10.1161/circresaha.116.309326 · Cited by 1,519 · see citing works
The Metabolic Underpinnings of Ferroptosis
Zheng, J., & Conrad, M. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2020.10.011 · Cited by 1,338 · see citing works
Protein kinase C activation and the development of diabetic complications.
Koya, D., & King, G. L. (1998) · Diabetes · doi:10.2337/diabetes.47.6.859 · Cited by 1,335 · see citing works
Barber, A. J., Lieth, E., Khin, S. A., Antonetti, D. A., Buchanan, A. G., & Gardner, T. W. (1998) · Journal of Clinical Investigation · doi:10.1172/jci2425 · Cited by 1,298 · see citing works
The progress in understanding and treatment of diabetic retinopathy
Stitt, A. W., Curtis, T. M., Chen, M., Medina, R. J., McKay, G. J., Jenkins, A. J., Gardiner, T. A., Lyons, T. J., Hammes, H., Simó, R., et al. (2015) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2015.08.001 · Cited by 1,177 · see citing works
Cellular death, reactive oxygen species (ROS) and diabetic complications
Volpe, C. M. O., Villar-Delfino, P. H., dos Anjos, P. M. F., & Nogueira‐Machado, J. A. (2018) · Cell Death and Disease · doi:10.1038/s41419-017-0135-z · Cited by 1,168 · see citing works
Diabetes-Related Microvascular and Macrovascular Diseases in the Physical Therapy Setting
Cade, W. T. (2008) · Physical Therapy · doi:10.2522/ptj.20080008 · Cited by 1,096 · see citing works
Diabetic retinopathy: current understanding, mechanisms, and treatment strategies
Duh, E. J., Sun, J. K., & Stitt, A. W. (2017) · JCI Insight · doi:10.1172/jci.insight.93751 · Cited by 1,057 · see citing works
Canto, E. D., Ceriello, A., Rydén, L., Ferrini, M., Hansen, T. B., Schnell, O., Standl, E., & Beulens, J. W. J. (2019) · European Journal of Preventive Cardiology · doi:10.1177/2047487319878371 · Cited by 1,022 · see citing works
Oxidative Stress and Its Role in the Pathogenesis of Ischaemic Stroke
Allen, C., & Bayraktutan, U. (2009) · International Journal of Stroke · doi:10.1111/j.1747-4949.2009.00387.x · Cited by 969 · see citing works
Management of Diabetic Retinopathy
Mohamed, Q. A., Gillies, M. C., & Wong, T. Y. (2007) · JAMA · doi:10.1001/jama.298.8.902 · Cited by 905 · see citing works
Tan, Y., Zhang, Z., Zheng, C., Wintergerst, K. A., Keller, B. B., & Cai, L. (2020) · Nature Reviews Cardiology · doi:10.1038/s41569-020-0339-2 · Cited by 846 · see citing works
The Role of Sirtuins in Antioxidant and Redox Signaling
Singh, C. K., Chhabra, G., Ndiaye, M. A., Garcia‐Peterson, L. M., Mack, N. J., & Ahmad, N. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7290 · Cited by 812 · see citing works
Oxidative Stress in Neurodegenerative Diseases
Niedzielska, E., Smaga, I., Gawlik, M., Moniczewski, A., Stankowicz, P., Pera, J., & Filip, M. (2016) · Molecular Neurobiology · doi:10.1007/s12035-015-9337-5 · Cited by 800 · see citing works
Myocardial Cell Death in Human Diabetes
Frustaci, A., Kajstura, J., Chimenti, C., Jakoniuk, I., Leri, A., Maseri, A., Nadal-Ginard, B., & Anversa, P. (2000) · Circulation Research · doi:10.1161/01.res.87.12.1123 · Cited by 796 · see citing works
Panretinal Photocoagulation vs Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy
Gross, J. G., Glassman, A. R., Jampol, L. M., Inusah, S., Aiello, L. P., Antoszyk, A. N., Baker, C. W., Berger, B. B., Bressler, N. M., Browning, D. J., et al. (2015) · JAMA · doi:10.1001/jama.2015.15217 · Cited by 787 · see citing works
Angiogenesis and vasculogenesis as therapeutic strategies for postnatal neovascularization
Isner, J. M., & Asahara, T. (1999) · Journal of Clinical Investigation · doi:10.1172/jci6889 · Cited by 774 · see citing works
The aetiology and molecular landscape of insulin resistance
James, D. E., Stöckli, J., & Birnbaum, M. J. (2021) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-021-00390-6 · Cited by 701 · see citing works
Bhatti, J. S., Sehrawat, A., Mishra, J., Sidhu, I. S., Navik, U., Khullar, N., Kumar, S., Bhatti, G. K., & Reddy, P. (2022) · Free Radical Biology & Medicine · doi:10.1016/j.freeradbiomed.2022.03.019 · Cited by 649 · see citing works
Advances in the epidemiology, pathogenesis and management of diabetic peripheral neuropathy
Tesfaye, S. H., & Selvarajah, D. (2012) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.2239 · Cited by 621 · see citing works
Endogenous non-enzymatic antioxidants in the human body
Mirończuk-Chodakowska, I., Witkowska, A. M., & Zujko, M. E. (2017) · Advances in Medical Sciences · doi:10.1016/j.advms.2017.05.005 · Cited by 620 · see citing works
Williamson, G., Kay, C. D., & Crozier, A. (2018) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12351 · Cited by 607 · see citing works
Jiang, T., Sun, Q., & Chen, S. (2016) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.07.005 · Cited by 594 · see citing works
Microvascular Complications of Type 2 Diabetes Mellitus
Faselis, C. J., Katsimardou, A., Imprialos, K. P., Deligkaris, P., Kallistratos, M. S., & Dimitriadis, K. (2019) · Current Vascular Pharmacology · doi:10.2174/1570161117666190502103733 · Cited by 585 · see citing works
NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets
Zhang, Y., Murugesan, P., Huang, K., & Cai, H. “. (2019) · Nature Reviews Cardiology · doi:10.1038/s41569-019-0260-8 · Cited by 544 · see citing works
Oxford Textbook of Clinical Nephrology
Devuyst, O., & Pirson, Y. (2015) · doi:10.1093/med/9780199592548.001.0001 · Cited by 513 · see citing works
Hexosamines, insulin resistance, and the complications of diabetes: current status
Buse, M. G. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00329.2005 · Cited by 511 · see citing works
Diabetic Peripheral Neuropathy: Epidemiology, Diagnosis, and Pharmacotherapy
Iqbal, Z., Azmi, S., Yadav, R., Ferdousi, M., Kumar, M., Cuthbertson, D. J., Lim, J., Malik, R. A., & Alam, U. (2018) · Clinical Therapeutics · doi:10.1016/j.clinthera.2018.04.001 · Cited by 487 · see citing works
The Nrf2 System as a Potential Target for the Development of Indirect Antioxidants
Jung, K.-A., & Kwak, M. (2010) · Molecules · doi:10.3390/molecules15107266 · Cited by 476 · see citing works
Rada, P., Rojo, A. I., Evrard‐Todeschi, N., Innamorato, N. G., Cotte, A., Jaworski, T., Tobón-Velasco, J. C., Devijver, H., García‐Mayoral, M. F., LEUVEN, F. V., et al. (2012) · Molecular and Cellular Biology · doi:10.1128/mcb.00180-12 · Cited by 476 · see citing works
Nanostructured Lipid Carriers for Delivery of Chemotherapeutics: A Review
Haider, M. A., Abdin, S. M., Kamal, L., & Orive, G. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12030288 · Cited by 464 · see citing works
Prevalence of diabetes and its effects on stroke outcomes: A meta‐analysis and literature review
Lau, L., Lew, J., Borschmann, K., Thijs, V., & Ekinci, E. I. (2018) · Journal of Diabetes Investigation · doi:10.1111/jdi.12932 · Cited by 460 · see citing works
Resveratrol induces mitochondrial biogenesis in endothelial cells
Csiszár, A., Labinskyy, N., Pinto, J. T., Ballabh, P., Zhang, H., Losonczy, G., Pearson, K. J., de Cabo, R., Pacher, P., Zhang, C., et al. (2009) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00368.2009 · Cited by 450 · see citing works
Gut Microbiota and Complications of Type-2 Diabetes
Iatcu, O. C., Steen, A., & Covașă, M. (2021) · Nutrients · doi:10.3390/nu14010166 · Cited by 433 · see citing works
Interpreting global trends in type 2 diabetes complications and mortality
Ali, M. K., Pearson‐Stuttard, J., Selvin, E., & Gregg, E. W. (2021) · Diabetologia · doi:10.1007/s00125-021-05585-2 · Cited by 428 · see citing works
Retinal ganglion cells in diabetes
Kern, T. S., & Barber, A. J. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2008.156695 · Cited by 424 · see citing works
Diabetic Nephropathy: An Overview
Sagoo, M. K., & Gnudi, L. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9841-8_1 · Cited by 414 · see citing works
McCannel, C. A. (2011) · Retina · doi:10.1097/iae.0b013e31820a67e4 · Cited by 396 · see citing works
Sivaprasad, S., Prevost, A. T., Vasconcelos, J. C., Riddell, A., Murphy, C., Kelly, J., Bainbridge, J. W., Edwards, R. T., Hopkins, D., Hykin, P. G., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)31193-5 · Cited by 392 · see citing works
Duni, Α., Liakopoulos, V., Roumeliotis, S. K., Peschos, D., & Dounousi, E. C. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20153711 · Cited by 388 · see citing works
Wang, H., Liu, K., Geng, M., Gao, P., Wu, X., Hai, Y., Li, Y., Li, Y., Luo, L., Hayes, J. D., et al. (2013) · Cancer Research · doi:10.1158/0008-5472.can-12-3386 · Cited by 382 · see citing works
Protection of Cardiac Mitochondria by Overexpression of MnSOD Reduces Diabetic Cardiomyopathy
Shen, X., Zheng, S., Metreveli, N. S., & Epstein, P. N. (2006) · Diabetes · doi:10.2337/diabetes.55.03.06.db05-1039 · Cited by 377 · see citing works
Della‐Morte, D., Dave, K. R., DeFazio, R. A., Bao, Y. C., Raval, A. P., & Pérez‐Pinzón, M. A. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.01.017 · Cited by 375 · see citing works
Motohashi, H., Katsuoka, F., Engel, J. D., & Yamamoto, M. P. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0305902101 · Cited by 363 · see citing works
Folsom, A. R., Rasmussen, M. L., Chambless, L. E., Howard, G., Cooper, L. S., Schmidt, M. I., & HEISS, G. M. (1999) · Diabetes Care · doi:10.2337/diacare.22.7.1077 · Cited by 356 · see citing works
González, V. H., Campbell, J. H., Holekamp, N. M., Kiss, S., Loewenstein, A., Augustin, A. J., Ma, J., Ho, A. C., Patel, V. D., Whitcup, S. M., et al. (2016) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2016.09.012 · Cited by 353 · see citing works
Diabetic Retinopathy and Angiogenesis
Crawford, T., Alfaro, D. V., Kerrison, J. B., & Jablon, E. P. (2009) · Current Diabetes Reviews · doi:10.2174/157339909787314149 · Cited by 351 · see citing works
Progression of nephropathy in type 2 diabetic patients
Rossing, K., Christensen, P. K., Hovind, P. H., Tarnow, L., Rossing, P. R., & Parving, H. (2004) · Kidney International · doi:10.1111/j.1523-1755.2004.00925.x · Cited by 338 · see citing works
Jing, X., Chen, J., Dong, Y., Han, D., Zhao, H., Wang, X., Gao, F., Li, C., Cui, Z., Liu, Y., et al. (2018) · Health and Quality of Life Outcomes · doi:10.1186/s12955-018-1021-9 · Cited by 337 · see citing works
Oxidative stress, mitochondrial damage and diabetic retinopathy.
Kowluru, R., & Mishra, M. (2015) · Biochimica et Biophysica Acta · doi:10.1016/j.bbadis.2015.08.001 · Cited by 332 · see citing works
The aspirin story – from willow to wonder drug
Desborough, M., & Keeling, D. M. (2017) · British Journal of Haematology · doi:10.1111/bjh.14520 · Cited by 329 · see citing works
Angiogenesis and Inflammation Crosstalk in Diabetic Retinopathy
Capitão, M., & Soares, R. A. (2016) · Journal of Cellular Biochemistry · doi:10.1002/jcb.25575 · Cited by 310 · see citing works
Diabetes in developing countries
Misra, A., Gopalan, H., Jayawardena, R., Hills, A. P., Soares, M. J., Reza‐Albarrán, A., & Ramaiya, K. L. (2019) · Journal of Diabetes · doi:10.1111/1753-0407.12913 · Cited by 308 · see citing works
Cortés‐Martín, A., Selma, M. V., Tomás-Barberán, F. A., González‐Sarrías, A., & Espı́n, J. C. (2020) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201900952 · Cited by 305 · see citing works
Quercetin Alleviates Ferroptosis of Pancreatic β Cells in Type 2 Diabetes
Li, D., Jiang, C., Mei, G., Zhao, Y., Chen, L., Liu, J., Tang, Y., Gao, C., & Yao, P. (2020) · Nutrients · doi:10.3390/nu12102954 · Cited by 301 · see citing works
Yates, M. S., Tauchi, M., Katsuoka, F., Flanders, K. C., Liby, K. T., Honda, T., Gribble, G. W., Johnson, D. A., Johnson, J. A., Burton, N. C., et al. (2007) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-06-0516 · Cited by 292 · see citing works
Cardiovascular effects and molecular targets of resveratrol
Li, H., Xia, N., & Förstermann, U. (2012) · Nitric Oxide · doi:10.1016/j.niox.2011.12.006 · Cited by 288 · see citing works
The interaction between St John's wort and an oral contraceptive
Hall, S. D. (2003) · Clinical Pharmacology & Therapeutics · doi:10.1016/j.clpt.2003.08.009 · Cited by 286 · see citing works
Gupta, N. S., Mansoor, S., Sharma, A., Sapkal, A., Sheth, J. U., Falatoonzadeh, P., Kuppermann, B., & Kenney, M. C. (2013) · The Open Ophthalmology Journal · doi:10.2174/1874364101307010004 · Cited by 286 · see citing works
Nitric oxide, oxidative stress, and progression of chronic renal failure
Modlinger, P., Wilcox, C. S., & Aslam, S. (2004) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2004.04.007 · Cited by 283 · see citing works
Asnaghi, V., Gerhardinger, C., Hoehn, T., Adeboje, A., & Lorenzi, M. (2003) · Diabetes · doi:10.2337/diabetes.52.2.506 · Cited by 279 · see citing works
Mechanism of Ferroptosis and Its Role in Type 2 Diabetes Mellitus
Sha, W., Hu, F., Yang, X., Chu, Y., & Bu, S. (2021) · Journal of Diabetes Research · doi:10.1155/2021/9999612 · Cited by 273 · see citing works
Beyond repression of Nrf2: An update on Keap1
Kopacz, A., Klóska, D., Forman, H. J., Józkowicz, A., & Grochot‐Przeczek, A. (2020) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2020.03.023 · Cited by 262 · see citing works
The Oxidative Stress and Mitochondrial Dysfunction during the Pathogenesis of Diabetic Retinopathy
Wu, M., Yiang, G., Lai, T.-T., & Li, C. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/3420187 · Cited by 252 · see citing works
Diabetic Cardiomyopathy: Current and Future Therapies. Beyond Glycemic Control
Borghetti, G., von Lewinski, D., Eaton, D., Sourij, H., Houser, S. R., & Wallner, M. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01514 · Cited by 245 · see citing works
Antioxidant Profile and Early Outcome in Stroke Patients
Cherubini, A., Polidori, M. C., Bregnocchi, M., Pezzuto, S., Cecchetti, R., Ingegni, T., Iorio, A. D., Senin, U., & Mecocci, P. (2000) · Stroke · doi:10.1161/01.str.31.10.2295 · Cited by 244 · see citing works
Manach, C., Milenković, D., de Wiele, T. V., Rodriguez‐Mateos, A., de Roos, B., García‐Conesa, M., Landberg, R., Gibney, E. R., Heinonen, M., Tomás-Barberán, F. A., et al. (2016) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201600557 · Cited by 236 · see citing works
An updated overview on metal nanoparticles toxicity
Medici, S., Peana, M., Pelucelli, A., & Zoroddu, M. A. (2021) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2021.06.020 · Cited by 228 · see citing works
Sharma, A., Tate, M., Mathew, G., Vince, J. E., Ritchie, R. H., & de Haan, J. B. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00114 · Cited by 216 · see citing works
Ferroptosis as a mechanism of neurodegeneration in Alzheimer's disease
Jakaria, M., Belaidi, A. A., Bush, A. I., & Ayton, S. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15519 · Cited by 212 · see citing works
Nezu, M., Souma, T., Yu, L., Suzuki, T., Saigusa, D., Ito, S., Suzuki, N., & Yamamoto, M. P. (2016) · Kidney International · doi:10.1016/j.kint.2016.08.023 · Cited by 211 · see citing works
Mitochondrial dysfunction in diabetic kidney disease
Wei, P. Z., & Szeto, C. (2019) · Clinica Chimica Acta · doi:10.1016/j.cca.2019.07.005 · Cited by 207 · see citing works
Fang, W., Wang, C., He, Y., Zhou, Y., Peng, X., & Liu, S. (2017) · Acta Pharmacologica Sinica · doi:10.1038/aps.2017.50 · Cited by 204 · see citing works
Involvement of Advanced Glycation End Products in the Pathogenesis of Diabetic Retinopathy
Xu, J., Chen, L.-J., Yu, J., Wang, H.-J., Zhang, F., Liu, Q., & Wu, J. (2018) · Cellular Physiology and Biochemistry · doi:10.1159/000491897 · Cited by 204 · see citing works
Paul, S., Ali, A., & Katare, R. (2020) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2020.107613 · Cited by 204 · see citing works
Glycemic Variability and Oxidative Stress: A Link between Diabetes and Cardiovascular Disease?
Saisho, Y. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms151018381 · Cited by 200 · see citing works
Targeting the Nrf2–Keap1 antioxidant defence pathway for neurovascular protection in stroke
Alfieri, A., Srivastava, S., Siow, R. C. M., Modo, M., Fraser, P. A., & Mann, G. E. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2011.210294 · Cited by 198 · see citing works
Circulating Oxidative Stress Biomarkers in Clinical Studies on Type 2 Diabetes and Its Complications
Bigagli, E., & Lodovici, M. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/5953685 · Cited by 195 · see citing works
Al‐Numair, K. S., Govindasamy, C., Veeramani, C., & Alsaif, M. A. (2014) · Redox Report · doi:10.1179/1351000214y.0000000117 · Cited by 193 · see citing works
Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway
An, X., Zhang, Y., Cao, Y., Chen, J., Qin, H., & Yang, L. (2020) · Nutrients · doi:10.3390/nu12051516 · Cited by 192 · see citing works
Cerebrovascular Complications of Diabetes: Focus on Stroke
Ergul, A., Kelly-Cobbs, A. I., Abdalla, M., & Fagan, S. C. (2012) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/187153012800493477 · Cited by 190 · see citing works
Roles of Nrf2 in Protecting the Kidney from Oxidative Damage
Nezu, M., & Suzuki, N. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21082951 · Cited by 180 · see citing works
Advances in our understanding of diabetic retinopathy
Stitt, A. W., Lois, N., Medina, R. J., Adamson, P., & Curtis, T. M. (2013) · Clinical Science · doi:10.1042/cs20120588 · Cited by 179 · see citing works
Diabetes mellitus and stroke: A clinical update
Tun, N. N., Arunagirinathan, G., Munshi, S. K., & Pappachan, J. M. (2017) · World Journal of Diabetes · doi:10.4239/wjd.v8.i6.235 · Cited by 177 · see citing works
UCP2, a mitochondrial protein regulated at multiple levels
Donadelli, M., Dando, I., Fiorini, C., & Palmieri, M. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1407-0 · Cited by 176 · see citing works
Diabetes and Progression of Carotid Atherosclerosis
Wagenknecht, L. E., Zaccaro, D. J., Espeland, M. A., Karter, A. J., O’Leary, D. H., & Haffner, S. M. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000072273.67342.6d · Cited by 172 · see citing works
The Chemical Diversity of Bioactive Molecules and Therapeutic Potential of Medicinal Plants
Ramawat, K. G., Dass, S. K., & Mathur, M. (2008) · Springer eBooks · doi:10.1007/978-3-540-79116-4_2 · Cited by 171 · see citing works
Kowluru, R. A., Kern, T. S., & Engerman, R. L. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(96)00347-4 · Cited by 170 · see citing works
Naoi, M., Wu, Y., Shamoto‐Nagai, M., & Maruyama, W. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20102451 · Cited by 170 · see citing works
Catalase overexpression attenuates angiotensinogen expression and apoptosis in diabetic mice
Brezniceanu, Liu, F., Wei, (.-Z.-(.-Z., Tran, S., Sachetelli, S., Guo, D., Guo, D., Filep, J. G., Ingelfinger, J. R., & Chan, J. S. D. (2007) · Kidney International · doi:10.1038/sj.ki.5002188 · Cited by 169 · see citing works
The impact of diabetic retinopathy: perspectives from patient focus groups
Coyne, K. S. (2004) · Family Practice · doi:10.1093/fampra/cmh417 · Cited by 165 · see citing works
Fong, D. S., Girach, A., & BONEY, A. (2007) · Retina · doi:10.1097/iae.0b013e318042d32c · Cited by 163 · see citing works
Zhao, D., Yang, J. Z., & Yang, L. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/6437467 · Cited by 162 · see citing works
Brezniceanu, M.-L., Liu, F., Wei, C., Chénier, I., Godin, N., Zhang, S., Filep, J. G., Ingelfinger, J. R., & Chan, J. S. D. (2007) · Diabetes · doi:10.2337/db07-0013 · Cited by 161 · see citing works
Huang, W., Yan, Z., Li, D., Ma, Y., Zhou, J., & Sui, Z. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/1862462 · Cited by 158 · see citing works
Wang, F., Wang, L., Qu, C., Chen, L., Geng, Y., Cheng, C., Yu, S., Wang, D., Yang, L., Meng, Z., et al. (2021) · BMC Cancer · doi:10.1186/s12885-021-08158-z · Cited by 157 · see citing works
Hayden, M. R., Sowers, J. R., & Tyagi, S. C. (2005) · Cardiovascular Diabetology · doi:10.1186/1475-2840-4-9 · Cited by 156 · see citing works
Tan, H., Chen, J., Li, Y., Li, G., Zhong, Y., Li, G., Liu, L., & Li, Y. (2022) · Molecular Medicine · doi:10.1186/s10020-022-00481-w · Cited by 156 · see citing works
Jiang, Z., Zhuo, L., He, Y., Fu, Y., Shen, L., Xu, F., Gou, W., Miao, Z., Shuai, M., Liang, Y., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-30712-x · Cited by 156 · see citing works
Tsai, C.-Y., Wang, C.-C., Lai, T.-Y., Tsu, H.-N., Wang, C., Liang, H.-Y., & Kuo, W. (2013) · International Journal of Cardiology · doi:10.1016/j.ijcard.2012.12.004 · Cited by 153 · see citing works
Epigallocatechin gallate upregulates NRF2 to prevent diabetic nephropathy via disabling KEAP1
Sun, W., Liu, X., Zhang, H., Song, Y., Li, T., Liu, X., Liu, Y., Guo, L., Wang, F., Yang, T., et al. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.04.365 · Cited by 150 · see citing works
Biallosterski, C., van Velthoven, M. E. J., Michels, R. P. J., Schlingemann, R. O., DeVries, J. H., & Verbraak, F. D. (2007) · British Journal of Ophthalmology · doi:10.1136/bjo.2006.111534 · Cited by 149 · see citing works
Natural polyphenols as sirtuin 6 modulators
Rahnasto‐Rilla, M., Tyni, J., Huovinen, M., Jarho, E. M., Kulikowicz, T., Ravichandran, S., Bohr, V. A., Ferrucci, L., Lahtela-Kakkonen, M. K., & Moaddel, R. (2018) · Scientific Reports · doi:10.1038/s41598-018-22388-5 · Cited by 149 · see citing works
Zhang, T., Chi, Y., Kang, Y., Lu, H., Niu, H., Liu, W., & Li, Y. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27306 · Cited by 148 · see citing works
Fridlyand, L. E., & Philipson, L. H. (2004) · Diabetes · doi:10.2337/diabetes.53.8.1942 · Cited by 147 · see citing works
Hesperetin ameliorates diabetic nephropathy in rats by activating Nrf2/ARE/glyoxalase 1 pathway
Chen, Y., Kong, L., Tang, Z., Zhang, Y., Liu, Y., Wang, T., & Liu, Y. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.01.030 · Cited by 147 · see citing works
Iron metabolism and type 2 diabetes mellitus: A meta‐analysis and systematic review
Liu, J., Li, Q., Yang, Y., & Ma, L. (2020) · Journal of Diabetes Investigation · doi:10.1111/jdi.13216 · Cited by 146 · see citing works
Song, Y. J., Huang, L., & Yu, J. (2016) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2016.11.001 · Cited by 145 · see citing works
Annual dialysis data report 2017, JSDT Renal Data Registry
Nitta, K., Masakane, I., Hanafusa, N., Taniguchi, M., Hasegawa, T., Nakai, S., Goto, S., Wada, A., Hamano, T., Hoshino, J., et al. (2019) · Renal Replacement Therapy · doi:10.1186/s41100-019-0248-1 · Cited by 144 · see citing works
Mitochondrial quality surveillance as a therapeutic target in myocardial infarction
Zhu, H., Toan, S., Mui, D., & Zhou, H. (2020) · Acta Physiologica · doi:10.1111/apha.13590 · Cited by 142 · see citing works
Oxidative stress in chronic vascular disease: From prediction to prevention
Santilli, F., D’Ardes, D., & Davı̀, G. (2015) · Vascular Pharmacology · doi:10.1016/j.vph.2015.09.003 · Cited by 140 · see citing works
Alterations to the Blood–Retinal Barrier in Diabetes: Cytokines and Reactive Oxygen Species
Frey, T., & Antonetti, D. A. (2011) · Antioxidants and Redox Signaling · doi:10.1089/ars.2011.3906 · Cited by 137 · see citing works
Hotta, N., Kawamori, R., Fukuda, M., Shigeta, Y., & The Aldose Reductase Inhibitor–Diabetes Complications Trial Study Group (2012) · Diabetic Medicine · doi:10.1111/j.1464-5491.2012.03684.x · Cited by 135 · see citing works
Ahsan, M., Lekli, I., Ray, D., Yodoi, J., & Das, D. (2009) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2683 · Cited by 134 · see citing works
Tang, X., Li, X., Zhang, D., & Han, W. (2022) · Bioengineered · doi:10.1080/21655979.2022.2049471 · Cited by 133 · see citing works
Attenuation of Renal Injury in db/db Mice Overexpressing Superoxide Dismutase
DeRubertis, F. R., Craven, P. A., Melhem, M. F., & Salah, E. (2004) · Diabetes · doi:10.2337/diabetes.53.3.762 · Cited by 127 · see citing works
Martín‐Peláez, S., Mosele, J. I., Pizarro, N., Farràs, M., de la Torre, R., Subirana, I., Pérez-Cano, F. J., Castañer, O., Solà, R., Fernández‐Castillejo, S., et al. (2015) · Zeitschrift für Ernährungswissenschaft · doi:10.1007/s00394-015-1063-2 · Cited by 124 · see citing works
Thioredoxin Interacting Protein (TXNIP) and Pathogenesis of Diabetic Retinopathy
Singh, L. P. (2013) · Journal of Clinical & Experimental Ophthalmology · doi:10.4172/2155-9570.1000287 · Cited by 123 · see citing works
Clinical and research markers of oxidative stress in chronic kidney disease
Tucker, P. S., Dalbo, V. J., Han, T., & Kingsley, M. (2013) · Biomarkers · doi:10.3109/1354750x.2012.749302 · Cited by 123 · see citing works
Impact of processing on the bioavailability and vascular effects of blueberry (poly)phenols
Rodriguez‐Mateos, A., Pino‐García, R. D., George, T. W., Vidal‐Diez, A., Heiß, C., & Spencer, J. P. E. (2014) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201400231 · Cited by 123 · see citing works
Stroke in patients with diabetes mellitus
Mankovsky, B., & Ziegler, D. (2004) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.490 · Cited by 121 · see citing works
Wang, X., Meng, L., Zhao, L., Wang, Z., Liu, H., Liu, G., & Guan, G. (2016) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2016.12.005 · Cited by 121 · see citing works
Han, J., Wang, M., Xu, J., Shi, H., Ren, M., & Lou, H. (2014) · Neurochemical Research · doi:10.1007/s11064-014-1311-5 · Cited by 119 · see citing works
Manganese Superoxide Dismutase Dysfunction and the Pathogenesis of Kidney Disease
Kitada, M., Xu, J., Ogura, Y., Monno, I., & Koya, D. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00755 · Cited by 117 · see citing works
Polia, F., Pastor‐Belda, M., Martínez-Blázquez, J. A., Horcajada, M.-N., Tomás-Barberán, F. A., & Garcı́a-Villalba, R. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.1c07198 · Cited by 112 · see citing works
Evaluation of oxidative stress in patients with acute ischemic stroke.
Cojocaru, I. M., Cojocaru, M., Sapira, V., & Ionescu, A. (2013) · PubMed · Cited by 111 · see citing works
New Molecular Insights of Insulin in Diabetic Cardiomyopathy
Westermeier, F., Riquelme, J. A., Pávez, M., Garrido, V., Díaz, A., Verdejo, H., Castro, P., Garcı́a, L., & Lavandero, S. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2016.00125 · Cited by 111 · see citing works
Matsushima, S., Kinugawa, S., Ide, T., Matsusaka, H., Inoue, N., Ohta, Y., Yokota, T., Sunagawa, K., & Tsutsui, H. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00427.2006 · Cited by 110 · see citing works
Alaofi, A. L. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.01119 · Cited by 109 · see citing works
Oxidative Stress After Thrombolysis-Induced Reperfusion in Human Stroke
Domı́nguez, C., Delgado, P., Vilches, A., Martı́n-Gallán, P., Ribó, M., Santamarina, E., Molina, C. A., Corbeto, N., Rodríguez‐Sureda, V., Rosell, A., et al. (2010) · Stroke · doi:10.1161/strokeaha.109.571935 · Cited by 106 · see citing works
Ferroptosis as a Novel Therapeutic Target for Diabetes and Its Complications
Yang, X., & Yang, Y. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.853822 · Cited by 105 · see citing works
Glomerular VEGF resistance induced by PKCδ/SHP‐1 activation and contribution to diabetic nephropathy
Mima, A., Kitada, M., Geraldes, P., Li, Q., Matsumoto, M., Mizutani, K., Qi, W., Li, C., Leitges, M., Rask‐Madsen, C., et al. (2012) · The FASEB Journal · doi:10.1096/fj.11-202994 · Cited by 103 · see citing works
Nicorandil alleviates apoptosis in diabetic cardiomyopathy through PI3K/Akt pathway
Wang, X., Pan, J., Liu, D., Zhang, M., Li, X., Tian, J., Liu, M., Jin, T., & An, F. (2019) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14413 · Cited by 102 · see citing works
Sandireddy, R., Yerra, V. G., Komirishetty, P., Areti, A., & Kumar, A. (2015) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-015-0272-9 · Cited by 101 · see citing works
Bucolo, C., Drago, F., Maisto, R., Romano, G. L., D’Agata, V., Maugeri, G., & Giunta, S. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.28347 · Cited by 100 · see citing works
Bachewal, P., Gundu, C., Yerra, V. G., Kalvala, A. K., Areti, A., & Kumar, A. (2017) · BioFactors · doi:10.1002/biof.1397 · Cited by 99 · see citing works
The impact of diabetic retinopathy: understanding the patient's perspective
Fenwick, E., Pesudovs, K., Rees, G., Dirani, M., Kawasaki, R., Wong, T. Y., & Lamoureux, E. L. (2010) · British Journal of Ophthalmology · doi:10.1136/bjo.2010.191312 · Cited by 98 · see citing works
Calycosin plays a protective role in diabetic kidney disease through the regulation of ferroptosis
Huang, D., Shen, P., Wang, C., Gao, J., Ye, C., & Wu, F. (2022) · Pharmaceutical Biology · doi:10.1080/13880209.2022.2067572 · Cited by 98 · see citing works
Kim, W., Lee, J. W., Suh, Y. H., Lee, H. J., Lee, S. H., Oh, Y. K., Gao, B., & Jung, M. H. (2006) · Cellular Signalling · doi:10.1016/j.cellsig.2006.10.004 · Cited by 96 · see citing works
Drummond, E. M., Harbourne, N., Marete, E. N., Martyn, D. M., Jacquier, J., O’Riordan, D., & Gibney, E. R. (2012) · Phytotherapy Research · doi:10.1002/ptr.4753 · Cited by 93 · see citing works
Angiogenic Growth Factors and their Inhibitors in Diabetic Retinopathy
Praidou, A., Androudi, S. N., BRAZITIKOS, P. D., Karakiulakis, G., Papakonstantinou, E., & Dimitrakos, S. A. (2010) · Current Diabetes Reviews · doi:10.2174/157339910793360815 · Cited by 92 · see citing works
Zhou, Y. (2020) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s249382 · Cited by 88 · see citing works
Wubben, T. J., Johnson, M. W., Sohn, E. H., Peairs, J. J., Kay, C. N., Kim, S. J., Gardner, T. W., Paulus, Y. M., Zacks, D. N., Steinle, N. C., et al. (2019) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2019.03.005 · Cited by 86 · see citing works
Zehden, J., Mortensen, X. M., Reddy, A. K., & Zhang, A. Y. (2022) · Current Diabetes Reports · doi:10.1007/s11892-022-01491-y · Cited by 86 · see citing works
Yu, Q., Lee, C. F., Wang, W., Karamanlidis, G., Kuroda, J., Matsushima, S., Sadoshima, J., & Tian, R. (2014) · Journal of the American Heart Association · doi:10.1161/jaha.113.000555 · Cited by 84 · see citing works
Roxo, D. F., Arcaro, C. A., Gutierres, V. O., Costa, M. C., Oliveira, J. O., Lima, T. F. O., Assis, R. P., Brunetti, I. L., & Baviera, A. M. (2019) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-019-0431-0 · Cited by 84 · see citing works
Chaudhary, K., Promsote, W., Ananth, S., Veeranan‐Karmegam, R., Tawfik, A. M., Arjunan, P., Martin, P. M., Smith, S. B., Thangaraju, M., Kisselev, O. G., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-21276-2 · Cited by 83 · see citing works
Hasler, C. M., & Blumberg, J. B. (1999) · Journal of Nutrition · doi:10.1093/jn/129.3.756s · Cited by 81 · see citing works
Zhou, Y., Huang, Y., Ji, X., Wang, X., Shen, L., & Wang, Y. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgz252 · Cited by 81 · see citing works
Diabetes and cognitive impairment
Biessels, G. J., Koffeman, A. R., & Scheltens, P. (2005) · Journal of Neurology · doi:10.1007/s00415-005-0036-4 · Cited by 78 · see citing works
Polyphenols and Intestinal Health
Martinez, K., Mackert, J. D., & McIntosh, M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805376-8.00018-6 · Cited by 78 · see citing works
Current Status and Challenges of NRF2 as a Potential Therapeutic Target for Diabetic Cardiomyopathy
Ge, Z., Lian, Q., Mao, X., & Xia, Z. (2019) · International Heart Journal · doi:10.1536/ihj.18-476 · Cited by 78 · see citing works
Cardiometabolic risk and gut microbial phytoestrogen metabolite phenotypes
Frankenfeld, C. L. (2016) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201500900 · Cited by 76 · see citing works
Role of oxidative stress in endothelial insulin resistance
Paneni, F. (2015) · World Journal of Diabetes · doi:10.4239/wjd.v6.i2.326 · Cited by 75 · see citing works
Metabolic Changes and Oxidative Stress in Diabetic Kidney Disease
Sakashita, M., Tanaka, T., & Inagi, R. (2021) · Antioxidants · doi:10.3390/antiox10071143 · Cited by 74 · see citing works
Impact of Diabetic Retinopathy on Vision-Specific Function
Lamoureux, E. L., Tai, E. S., Thumboo, J., Kawasaki, R., Saw, S., Mitchell, P. L. R., & Wong, T. Y. (2010) · Ophthalmology · doi:10.1016/j.ophtha.2009.09.035 · Cited by 72 · see citing works
Hong, Y. A., Lim, J. H., Kim, M. Y., Kim, Y., Park, H. S., Kim, H. W., Choi, B. S., Chang, Y. S., Kim, H. W., Kim, T., et al. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7207 · Cited by 72 · see citing works
The Benefits of Flavonoids in Diabetic Retinopathy
Matos, A. L., Bruno, D. F., Ambrósio, A. F., & Santos, P. F. (2020) · Nutrients · doi:10.3390/nu12103169 · Cited by 71 · see citing works
Gu, R., Wang, Y., Long, B., Kennelly, E. J., Wu, S., Liu, B., Li, P., & Long, C. (2014) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b14-00084 · Cited by 70 · see citing works
Kim, A., Lee, W., & Yun, J. (2017) · Nutrition Research and Practice · doi:10.4162/nrp.2017.11.5.430 · Cited by 70 · see citing works
Zhu, X., Chen, Y., Chen, Q., Yang, H., & Xie, X. S. (2018) · Journal of Diabetes Research · doi:10.1155/2018/6730315 · Cited by 69 · see citing works
Zhang, L., Chen, Z., Gong, W., Zou, Y., Xu, F., Chen, L., & Huang, H. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00512 · Cited by 69 · see citing works
Mittal, R., Kumar, A., Singh, D. P., Bishnoi, M., & Nag, T. C. (2017) · Inflammopharmacology · doi:10.1007/s10787-017-0413-5 · Cited by 68 · see citing works
Catalytic Antioxidants in the Kidney
Hong, Y. A., & Park, C. W. (2021) · Antioxidants · doi:10.3390/antiox10010130 · Cited by 68 · see citing works
mTOR controls ChREBP transcriptional activity and pancreatic β cell survival under diabetic stress
Chau, G. C., Im, D. U., Kang, T. M., Bae, J. M., Kim, W., Pyo, S., Moon, E.-Y., & Um, S. H. (2017) · Journal of Cell Biology · doi:10.1083/jcb.201701085 · Cited by 67 · see citing works
Mohan, T., Narasimhan, K. K. S., Ravi, D. B., Velusamy, P., Chandrasekar, N., Chakrapani, L. N., Srinivasan, A., Karthikeyan, P., Kannan, P., Tamilarasan, B., et al. (2020) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2020.07.037 · Cited by 66 · see citing works
Oxidative Stress Signaling Mediated Pathogenesis of Diabetic Cardiomyopathy
Tang, Z., Wang, P., Dong, C., Zhang, J., Wang, X., & Pei, H. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/5913374 · Cited by 66 · see citing works
Yang, H., Li, Q., Wang, Z., Zhou, W., Fan, S.-R., Ma, R., Xue, L., Yang, L., Li, Y., Tan, H.-L., et al. (2016) · Neural Regeneration Research · doi:10.4103/1673-5374.177745 · Cited by 64 · see citing works
Kuo, C.-W., Shen, C., Tung, Y., Chen, H., Chen, Y., Chang, W.-H., Cheng, K.-C., Yang, S., & Chen, C. (2015) · Life Sciences · doi:10.1016/j.lfs.2015.04.018 · Cited by 62 · see citing works
Xie, T., Chen, X., Chen, W., Huang, S., Peng, X., Tian, L., Wu, X., & Huang, Y. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.796565 · Cited by 62 · see citing works
Škėmienė, K., Liobikas, J., & Borutaitė, V. (2015) · FEBS Journal · doi:10.1111/febs.13195 · Cited by 61 · see citing works
Chatham, J. C., Young, M. E., & Zhang, J. (2020) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2020.08.005 · Cited by 59 · see citing works
The Role of Akt2 in the Protective Effect of Fenofibrate against Diabetic Nephropathy
Cheng, Y., Zhang, X., Ma, F., Sun, W., Wang, W., Yu, J., Shi, Y., Cai, L., & Xu, Z. (2020) · International Journal of Biological Sciences · doi:10.7150/ijbs.40643 · Cited by 55 · see citing works
Liu, J., Chen, S., Biswas, S., Nagrani, N., Chu, Y., Chakrabarti, S., & Feng, B. (2020) · Physiological Reports · doi:10.14814/phy2.14331 · Cited by 54 · see citing works
Abukhabta, S., Ghawi, S. K., Karatzas, K. A. G., Charalampopoulos, D., McDougall, G. J., Allwood, J. W., Verrall, S. R., Lavery, S., Latimer, C., Pourshahidi, L. K., et al. (2020) · European Journal of Nutrition · doi:10.1007/s00394-020-02322-0 · Cited by 53 · see citing works
Wang, Y.-H., Chang, D., Zhao, M., & Chen, M. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/2948248 · Cited by 53 · see citing works
Seco-Cervera, M., González-Cabo, P., Pallardó, F., Romá-Mateo, C., & García-Giménez, J. (2020) · Antioxidants · doi:10.3390/antiox9121257 · Cited by 52 · see citing works
Cortés‐Martín, A., Iglesias‐Aguirre, C. E., Meoro, A., Selma, M. V., & Espı́n, J. C. (2021) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202001048 · Cited by 52 · see citing works
Hu, H., Lei, Y., Zhang, W., & Luo, X. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.841818 · Cited by 52 · see citing works
Xian, Y., Gao, Y., Lv, W., Ma, X., Hu, J., Chi, J., Wang, W., & Wang, Y. (2020) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-019-01777-1 · Cited by 51 · see citing works
Yehuda, I., Madar, Z., Leikin-Frenkel, A. I., & Tamir, S. (2015) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201400876 · Cited by 49 · see citing works
Flagged first, then by citations
2 of the 254 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- [13]Bharadwaj K.C. Gupta T. Singh R.M. Chapter 9—Alkaloid Group of Cinchona Officinalis: Structural, Synthetic, and Medicinal Aspects Synthesis of Medicinal Agents from Plants Tewari A. Tiwari S. Elsevier Amsterdam, The Netherlands 2018 205 227 978-0-08-102071-5
Cited by
Sorted by citations
Reactive Oxygen Species, Toxicity, Oxidative Stress, and Antioxidants: Chronic Diseases and Aging
Jomova, K., Raptova, R., Alomar, S. Y., Alwasel, S. H., Nepovimova, E., Kuca, K., & Valko, M. (2023) · Archives of Toxicology · doi:10.1007/s00204-023-03562-9 · Cited by 2,638 · see citing works
Diabetic Nephropathy: Pathogenesis, Mechanisms, and Therapeutic Strategies
Dwivedi, S., & Sikarwar, M. S. (2024) · Hormone and Metabolic Research · doi:10.1055/a-2435-8264 · Cited by 115 · see citing works
Munteanu, C., Turnea, M. A., & Rotariu, M. (2023) · Antioxidants · doi:10.3390/antiox12091737 · Cited by 99 · see citing works
Darenskaya, M. A., Kolesnikov, S. I., Semenova, N. V., & Kolesnikova, L. I. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241512378 · Cited by 97 · see citing works
Pereira, L., & Valado, A. (2023) · Life · doi:10.3390/life13091831 · Cited by 59 · see citing works
Nuñez-Selles, A. J., Nuñez-Musa, R. A., & Guillen-Marmolejos, R. A. (2025) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2025.1611842 · Cited by 51 · see citing works
Phytochemicals and Biological Activities of Walnut Septum: A Systematic Review
Mateș, L., Rusu, M. E., & Popa, D. (2023) · Antioxidants · doi:10.3390/antiox12030604 · Cited by 47 · see citing works
Diabetes and the associated complications: The role of antioxidants in diabetes therapy and care
Dilworth, L., Stennett, D., Facey, A., Omoruyi, F. O., Mohansingh, S., & Omoruyi, F. O. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117641 · Cited by 48 · see citing works
Yi, X., Wang, Q., Zhang, M., Shu, Q., & Zhu, J. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117217 · Cited by 38 · see citing works
Lin, Q., Jia, L., Lei, M., Gao, D., Zhang, N., Sha, L., Liu, X., & Liu, Y. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2023.107054 · Cited by 29 · see citing works
Kacemi, R., & Campos, M. G. (2023) · Nutrients · doi:10.3390/nu15102413 · Cited by 27 · see citing works
Boshra, A. E., Hassan, N. H., Ibrahim, S., Hassanen, E. I., Eldin, Z. E., & Ali, S. E. (2024) · Scientific Reports · doi:10.1038/s41598-024-81949-z · Cited by 26 · see citing works
Chen, Q., Qiu, F.-S., Xie, W., Yu, W.-Y., Su, Z.-A., Qin, G., Kang, Y.-K., Jiang, S.-L., & Yu, C.-H. (2024) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2024.124758 · Cited by 25 · see citing works
Mubeen, B., Hasnain, A., Naqvi, S. A. H., Hakim, F., Naqvi, S. S. H., Hassan, M. Z., Iqbal, M. U., Moustafa, M., Alshaharni, M. O., & Duan, M. (2025) · Phyton · doi:10.32604/phyton.2025.064056 · Cited by 25 · see citing works
Chang, T., Li, Y.-Z., Mo, H.-W., Chen, C., Lin, L., Chang, C. L., & Chen, J. (2024) · Science Translational Medicine · doi:10.1126/scitranslmed.adn1507 · Cited by 24 · see citing works
Pasini, A. M. F., & Cominacini, L. (2023) · Antioxidants · doi:10.3390/antiox12040890 · Cited by 21 · see citing works
Deeb, S. E., Ashour, E. A., El-Hack, M. E. A., El-Maaty, M. A., Youssef, I. M., Adil, S., Elolimy, A. A., & Swelum, A. A. (2024) · Poultry Science · doi:10.1016/j.psj.2024.104396 · Cited by 19 · see citing works
RetractedZhou, Z. H., Li, C., Zeng, Y., Huang, T., Jiang, X., Yu, D., & Wang, K. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.136688 · Cited by 20 · see citing works
Bappi, M. H., Prottay, A. A. S., Al-Khafaji, K., Akbor, M. S., Hossain, M. K., Islam, M. S., Asha, A. I., Medeiros, C. R., Tahim, C. M., Lucetti, E. C. P., et al. (2023) · Food and Chemical Toxicology · doi:10.1016/j.fct.2023.114068 · Cited by 17 · see citing works
Tonin, G., Dolžan, V., & Klen, J. (2024) · Antioxidants · doi:10.3390/antiox13030277 · Cited by 15 · see citing works
Ye, L., Yan, Y., & Yan, J. (2025) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2025.123301 · Cited by 13 · see citing works
Vaccinium as Potential Therapy for Diabetes and Microvascular Complications
Huang, H. C., Luo, Y., Wang, Q., Zhang, Y., Li, Z., He, R., Chen, X., & Dong, Z. (2023) · Nutrients · doi:10.3390/nu15092031 · Cited by 16 · see citing works
Arabnozari, H., Shaki, F., Najjari, A., Sharifianjazi, F., Sarker, S. D., Habibi, E., & Nahar, L. (2024) · Scientific Reports · doi:10.1038/s41598-024-69220-x · Cited by 12 · see citing works
Situmorang, P. C., Zuhra, C. F., Lutfia, A., Pasaribu, K. M., Hardiyanti, R., & Nugraha, A. P. (2025) · Journal of Functional Foods · doi:10.1016/j.jff.2025.106799 · Cited by 11 · see citing works
Nguyen, N. H., Pham, T. H. T., Nguyen, N. T. T., Bui, V. K. H., & Giau, V. V. (2025) · Chemistry & Biodiversity · doi:10.1002/cbdv.202402806 · Cited by 10 · see citing works
Sher, E. K., Džidić-Krivić, A., Karahmet, A., Beća-Zećo, M., Farhat, E. K., Softič, A., & Sher, F. (2023) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2023.102901 · Cited by 10 · see citing works
Khatun, H., Sami, S. A., Mim, F. S., Kumar, P., Islam, A., Rian, I. A. M., Rahman, M. A., Riya, S. I., Lokman, M., Mamun, A., et al. (2025) · Scientifica · doi:10.1155/sci5/6516268 · Cited by 8 · see citing works
Sun, L.-Y., Sun, G.-Y., Nan, Y., Wang, H., Sun, Y., Shi, Y., Yang, Y., & Wang, Q.-F. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1778473 · Cited by 8 · see citing works
Bioactive Compounds in Blueberry Fruit and Their Antidiabetic Activity
Sharma, K., Malathi, V. M., Thappa, C., Kour, N., & Abhimannue, A. P. (2024) · Current Food Science and Technology Reports · doi:10.1007/s43555-024-00040-w · Cited by 8 · see citing works
Peng, J. M., Abdulla, R., Liu, X., He, F., Xin, X., & Aisa, H. A. (2024) · Nutrients · doi:10.3390/nu16172944 · Cited by 7 · see citing works
Zaman, W., & Amin, A. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47100841 · Cited by 8 · see citing works
Rocha, S., Amaro, A., Ferreira-Junior, M. D., Proença, C., Silva, A. M. S., Costa, V. M., Oliveira, S., Fonseca, D. A., Silva, S., Corvo, M. L., et al. (2024) · Pharmaceutics · doi:10.3390/pharmaceutics16020261 · Cited by 7 · see citing works
Global research trends and hotspots of oxidative stress in diabetic retinopathy (2000-2024)
Du, K., Liu, Y., Zhao, X., Wang, H., Wan, X., Sun, X., & Luo, W. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1428411 · Cited by 5 · see citing works
Thakur, M., Verma, R., Kumar, D., Manickam, S., & Malik, T. (2025) · BioMed Research International · doi:10.1155/bmri/6650124 · Cited by 5 · see citing works
Kousar, S., Hussain, A., Aslam, B., Faisal, M. N., Siddique, R., Sajid, M. R., & Khan, R. U. (2025) · Chemistry & Biodiversity · doi:10.1002/cbdv.202500410 · Cited by 5 · see citing works
Eranda, D. H. U., Panpipat, W., Karnjanapratum, S., Castro-Muñoz, R., & Chaijan, M. (2026) · Food and Bioprocess Technology · doi:10.1007/s11947-026-04292-3 · Cited by 5 · see citing works
Phytochemicals from natural sources classification physiological roles and health benefits
Kafi, A. A., Barsha, K. A., Mukta, T. A., Islam, S. M. R., Hoque, M. M., John, A. S., & Mahmud, M. N. (2026) · Discover Chemistry. · doi:10.1007/s44371-026-00781-8 · Cited by 5 · see citing works
Park, C., Cha, H., Hong, S. H., Noh, J. S., Hong, S. H., Kim, G., Shim, J., Hyun, J. W., & Choi, Y. H. (2025) · Biomolecules & Therapeutics · doi:10.4062/biomolther.2025.025 · Cited by 4 · see citing works
Molecular Insights Into Carotenoid‐Based Interventions for Diabetic Retinopathy
Liu, C., Wang, X., Liu, M., & Cao, X. (2025) · Nutrition Bulletin · doi:10.1111/nbu.70015 · Cited by 4 · see citing works
Oxidative Stress and Antioxidant Interventions in Type 2 Diabetes
Sohail, A., Hasnain, M. M., Haq, M. E. U., Nasir, I., Sufyan, R., Khan, M., & Ullah, I. (2024) · Biochemistry · doi:10.5772/intechopen.1006081 · Cited by 4 · see citing works
Clitoria ternatea (Butterfly Pea) – A Plant with Antioxidant and Antidiabetic Properties
Sowmya, R., Supriya, V., & Rajkumar, M. (2023) · Indian Journal of Science and Technology · doi:10.17485/ijst/v16i31.1166 · Cited by 4 · see citing works
Nazir, M., Haq, M. A., Ali, S. A., Saeed, S. M. G., Ajmal, M. A., Nisar, M. F., Khan, T. A., Τσούπρας, Α., & Naz, S. (2025) · Chemistry & Biodiversity · doi:10.1002/cbdv.202500020 · Cited by 3 · see citing works
Li, K., Chen, S., & Wu, S. (2024) · Journal of Polymer Science · doi:10.1002/pol.20240483 · Cited by 3 · see citing works
Ahmed, M. S., Hasan, M. M.-U., Ahmmed, R., Bismillah, M., Rahman, M. A., Hossain, M. I., Khan, M. H., & Islam, M. A. (2025) · South African Journal of Botany · doi:10.1016/j.sajb.2025.07.013 · Cited by 3 · see citing works
Nuchuchua, O., Seephan, S., Srinuanchai, W., Temviriyanukul, P., & Pongrakhananon, V. (2025) · Antioxidants · doi:10.3390/antiox14040427 · Cited by 3 · see citing works
Wang, M., Yu, X., Liu, C., & Liu, Y. (2025) · Archives of Endocrinology and Metabolism · doi:10.20945/2359-4292-2024-0377 · Cited by 2 · see citing works
Tufan, Ö., Kaya, D. E., Dörtbudak, M. B., KILINÇ, B., BÜYÜKTAŞKAPULU, İ., Göktürk, F., Demircioğlu, M., Er, A., & Dik, B. (2025) · BMC Pharmacology and Toxicology · doi:10.1186/s40360-025-01071-2 · Cited by 2 · see citing works
Singh, G., Passari, A. K., Kumar, N. S., Kumar, B., Nayak, S. C., Ram, H., & Singh, B. P. (2024) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-024-05005-2 · Cited by 2 · see citing works
Appiah, C. A., Ngounda, J. O., Boakye‐Yiadom, M., Mills-Robertson, F. C., Nel, M., Johnson, R., & Walsh, C. M. (2025) · Diabetology · doi:10.3390/diabetology6010006 · Cited by 2 · see citing works
Tenuta, M. C., Deguin, B., Loizzo, M. R., Grande, F., Brindisi, M., Occhiuzzi, M. A., Dugay, A., Bonesi, M., Malfa, G. A., & Tundis, R. (2025) · Journal of Functional Foods · doi:10.1016/j.jff.2025.107002 · Cited by 2 · see citing works
Witharana, V. S. B., & Jayasinghe, C. V. L. (2023) · Preprints.org · doi:10.20944/preprints202309.0260.v1 · Cited by 2 · see citing works
ROS-mediated redox signaling in diabetic wound healing
Momtaz, S., & Abdollahi, M. R. (2024) · Advances in biogerontology · doi:10.1016/bs.abger.2024.05.013 · Cited by 1 · see citing works
Saeed, Z. K., Al-Samydai, A. M., Alqaraleh, M., Qinna, N. A., Ghanim, B. Y., Mayyas, A. H., Al-Tawalbeh, D. M., Alsotari, S. T., Alshaer, W., Al-Mamoori, F. F., et al. (2024) · Indian Journal of Pharmaceutical Education and Research · doi:10.5530/ijper.58.3s.100 · Cited by 1 · see citing works
Biomarkers and Novel Therapies of Diabetic Neuropathy: An Updated Review
Aziz, N., Nehere, S. V., Sinha, R., Satyarthy, R., Prajapati, H., Panigrahy, U. P., Sharma, M. C., Kumar, P., & Wal, P. (2024) · Current Pharmaceutical Biotechnology · doi:10.2174/0113892010316518240924071259 · Cited by 1 · see citing works
Fithria, R. F., Huda, M. B., Mohamed, F., & LINGYU, S. (2024) · International Journal of Pharmacy and Pharmaceutical Sciences · doi:10.22159/ijpps.2024v16i11.52366 · Cited by 1 · see citing works
Sinuhaji, T. R. F., Ramadhani, S., Setiawan, V. K., & Baroroh, U. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-04139-2 · Cited by 4 · see citing works
Investigation of Lancifortarene (LNF)-Zinc Oxide Nanocomposites for Antidiabetic Applications
Farooq, T., Hameed, A., Fakhar-e-alam, M., Saadullah, M., M.Adnan, Imran, M., Asher, A., Sikandar, S., Khalid, T., Arshad, S. F., et al. (2025) · BioNanoScience · doi:10.1007/s12668-025-01997-1 · Cited by 1 · see citing works
Andlib, N., Ali, R., Khan, N. J., Kumar, R., & Thakur, S. C. (2025) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2025.120455 · Cited by 1 · see citing works
Plant Based Diets in the Prevention and Management of Chronic Diseases: An updated Review
Aslam, M. M., Ain, Q. U., Amin, J., Fatima, S., Ain, Q. U., Fatima, K., & Suhail, J. (2025) · Journal of Microbiological Sciences · doi:10.38211/jms.2025.04.156 · Cited by 1 · see citing works
Fayad, E. M., Aljumaa, M. A., Rizk, H. A., Ghanem, A., Hathout, A., Ali, A. R., Alshaya, D. S., El-Mekkawy, H. I., salem, A. M., Mohammed, O. A., et al. (2026) · Tissue and Cell · doi:10.1016/j.tice.2026.103368 · Cited by 1 · see citing works
Alves, É. R., da Silva, J. G. M., de Melo, I. M. F., Santos, L. C. D. S., de França, M. M. S., Neto, C. L., Medina, V. B., Souza, F. D. A. L., Filho, L. D. V., Teixeira, Á. A. C., et al. (2026) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.70855 · Cited by 1 · see citing works
Abdullah, W. H., Alabedi, R. F., & Mussa, R. F. (2023) · Medical Journal of Indonesia · doi:10.13181/mji.oa.236382 · Cited by 1 · see citing works
Ubah, E. E., Irene, I. I., Oguamanam, K. C., Obike, C. A., & A.C, E. (2024) · Scientia Africana · doi:10.4314/sa.v23i2.13 · Cited by 1 · see citing works
Self-citationAl-Shaqsi, N. U., Al-Jahdhami, H., Khan, F., Ullah, S. M., Mohamad, S., Khan, A., Alam, T., Lim, S., Gibbons, S., Rehman, N. U., et al. (2025) · Journal of Essential Oil Bearing Plants · doi:10.1080/0972060x.2024.2443830 · Cited by 1 · see citing works
Ren, X., Zhao, M., & Du, J. (2025) · Asian Pacific Journal of Tropical Biomedicine · doi:10.4103/apjtb.apjtb_48_25 · Cited by 1 · see citing works
Mandour, D. A., Hulail, M. A. E., Ahmed, A. A., & ElNabtiti, M. S. (2023) · Egyptian Society of Clinical Toxicology Journal · doi:10.21608/esctj.2023.219317.1036
Oxidative stress prevention as an effective preventive strategy in type 2 diabetes mellitus
Bykov, Y. V. (2024) · Russian Journal of Preventive Medicine · doi:10.17116/profmed202427031117
Ubah, E. E., Ijeh, I. I., Egbuonu, A. C., Obike, C. A., & Oguamanam, K. C. (2024) · Tropical Journal of Natural Product Research · doi:10.26538/tjnpr/v8i5.40
Self-citationLestari, N. D., Agustini, S. M., Dliyauddin, M., Adharini, W. I., Nilamsari, R. V., Widodo, N., Rahayu, S., & Rifa’i, M. (2024) · Medicinski Glasnik · doi:10.17392/1685-21-02
Гуляев, А. Е., Sergazy, S., Urazbayeva, A., Shulgau, Z., & Бенберин, В. В. (2024) · Farmaciâ Kazahstana · doi:10.53511/pharmkaz.2024.93.64.013
Yang, J., Seo, H.-J., Wang, Y., Гао, Д., Yoo, N.-H., Park, J.-H., Seong, E. S., Kwon, Y.-S., Kim, S.-J., & Kim, M. J. (2024) · Agronomy · doi:10.3390/agronomy14112705
Ugwu, M. N., Ogwoni, H. A., Emuru, E. O., Ogbonna, C. G., Busy, C. O., Okutepa, C. I., Eze, I. S., & Peter, U. V. (2025) · African Journal of Biology and Medical Research · doi:10.52589/ajbmr-lss5q9vr
Cognitive enhancement: fueling the brain with functional foods
Khanashyam, A. C., Ramesh, B., Shanker, M. A., James, M., Shah, K., Thorakkattu, P., & Nirmal, N. P. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-28862-3.00005-4
Tang, X., Tian, Z., Li, C., Zhu, D., & Liu, H. (2025) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-025-03394-4
Fithria, R. F., Huda, M. B., Mohamed, F., & LINGYU, S. (2025) · Asian Journal of Pharmaceutical and Clinical Research · doi:10.22159/ajpcr.2025v18i7.55496
Significance of phytochemicals in metabolic disorders
Tripathi, M., Padalia, K., & Agnihotri, V. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-31698-2.00025-4
Phytochemicals and metabolic disorders: managing diabetes, obesity, and metabolic syndrome
Srinivasa, U. M., Paramasivan, K., & Anitha, R. E. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-26494-8.00004-5
The therapeutic potential of Vanilla planifolia: how its phytochemicals combat diabetes?
Tan, B. L., Zulkifli, F., & Norhaizan, M. E. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1752315
Sen, K., Sakarwal, A., Ram, H., Saha, S. K., Rana, N. K., Yadav, D., Shukla, S. D., Yadav, M. K., Vellingiri, B., & Kumar, V. D. (2026) · Ibrain · doi:10.1002/ibra.70019
Role of Underutilized Plant-Derived Metal and Metal Oxide-Based Nanoparticles Against Diabetes
Iqbal, H., Bhaduri, A., Dulta, K., Nitin, & Nene, A. (2026) · Springer eBooks · doi:10.1007/978-3-032-20384-7_11
Karimi, S., Koohpeyma, F., & Jahangiri, A. (2026) · Zygote · doi:10.1017/s0967199426100379
Askari, S., & Eskandari, M. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-32888-6.00004-9
Nacius, Y. V., Fernandes, G. D. S. T., Gul, K., Ara, B., Vieira, N. Q. A., Costa, J. A. S., Fernandes, D. A., de Barros, E. C., Taube, P. S., & Lara, T. S. (2026) · Pharmacological Research - Natural Products · doi:10.1016/j.prenap.2026.100807
Apocynin in Diabetes: Modulation of Oxidative Stress and Inflammatory Signaling
Khan, U. R., Otari, K. V., & Kale, A. Y. (2026) · Biosciences Biotechnology Research Asia · doi:10.13005/bbra/3517
Diabetic nephropathy: pathophysiology, biomarkers and treatment strategies
Singh, A., Maheshwari, S., Kumar, P., Agrahari, M., & Singh, A. K. (2026) · Journal of The Egyptian Society of Nephrology and Transplantation · doi:10.4103/jesnt.jesnt_2_26
Rahayu, I., Arfian, N., Timotius, K. H., & Wahyuningsih, M. S. H. (2026) · Journal of Applied Pharmaceutical Science · doi:10.1177/22313354261464247
Verma, D. K., Prabhakar, P., Dadrwal, B. K., Sıngh, S., Gupta, A. K., Patel, A. R., Srivastav, P. P., & Aguilar, C. N. (2026) · Preparative Biochemistry & Biotechnology · doi:10.1080/10826068.2026.2716078
Das, K. K., Debnath, B., & Sen, S. (2026) · Journal of drug targeting · doi:10.1080/1061186x.2026.2741698
Ahmed, M. S., Hasan, M. T., Bismillah, M., Rahman, M. M., Hossain, M. A., Khan, M. H., & Islam, M. A. (2026) · Food Science & Nutrition · doi:10.1002/fsn3.72520
- Authors
- Akpoveso, O.-O. P., Ubah, E. E., & Obasanmi, G.
- Affiliations
- School of Basic Sciences, All American Institute of Medical Sciences, Black River, Saint Elizabeth Parish JMDEH03, Jamaica
- Michael Okpara University of Agriculture (NG)
- University of British Columbia (CA)
- Corresponding author
- Akpoveso, Oke-Oghene Philomena
- Obasanmi, Gideon
- Venue
- Antioxidants
- Publisher
- MDPI AG
- Published
- 2023-01-04
- Volume
- 12
- Issue
- 1
- Pages
- 123
- ISSN
- 2076-3921 (ISSN-L)
- PMC
- PMC9855127
- OpenAlex
- W4313494619
- Cited by
- 90
- References
- 254
- Citations by year
- 2026: 18 · 2025: 30 · 2024: 28 · 2023: 14
- FWCI
- 3.23
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Antioxidants (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- cIRcle (University of British Columbia) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Open Collections
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Natural Antidiabetic Agents Studies
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Health Sciences › Medicine › Physiology › Nitric Oxide and Endothelin Effects
- Keywords
- polyphenols, antioxidant phytochemicals, diabetic vascular complications, oxidative stress, hyperglycemia, insulin resistance, endothelial injury, diabetic retinopathy, diabetic nephropathy, diabetic peripheral neuropathy, endogenous antioxidant system, natural products, plant-derived drugs
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review