Sleep apnea and atrial fibrillation; 2012 update
Open accessAbstract
Atrial fibrillation (AF) and obstructive sleep apnea (OSA) are very prevalent diseases in modern society. Recent years have seen the emergence of a wide body of literature suggesting an important association between these two diseases. This review will provide a summary of this evidence as it currently exists. First, it will review the literature suggesting an association between AF and OSA by highlighting the prevalence of AF in OSA, the correlation of AF prevalence with OSA severity and the trend towards increased AF recurrence in patients with OSA after treatment for AF. Second, it will identify the possible pathophysiologic mechanisms for this association. In doing so, it will discuss the investigated effects of intrathoracic pressure changes, autonomic instability and atrial remodeling. Finally, it will review the evidence of the effect of treatment of OSA on AF, highlighting the role of continuous positive airway pressure (CPAP) in the treatment of OSA and its impact on AF prevalence and recurrence.
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Multiple pathophysiological mechanisms can contribute to AF in obstructive sleep apnoea, including autonomic dysfunction, hypoxia, hypercapnia, and inflammation.
“Multiple pathophysiological mechanisms can contribute to AF in obstructive sleep apnoea, including autonomic dysfunction, hypoxia, hypercapnia, and inflammation.”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [305]
AF has been associated with obstructive sleep apnoea.
“AF has been associated with obstructive sleep apnoea.”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [305]
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Seaborn, G. E. J., Pang, H., Akl, S. G., Redfearn, D., Simpson, C. S., Fitzpatrick, M., Munt, P. W., & Baranchuk, A. M. (2012) · Redalyc (Universidad Autónoma del Estado de México) · Cited by 3 · see citing works
Self-citation
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2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw210 · Cited by 6,418 · see citing works
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezw313 · Cited by 1,403 · see citing works
- Authors
- C Digby, G., & Baranchuk, A.
- Affiliations
- Queen's University (CA)
- Corresponding author
- Baranchuk, Adrian
- ORCID
- Baranchuk, Adrian
- Venue
- Current Cardiology Reviews
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2012-10-24
- Volume
- 8
- Issue
- 4
- Pages
- 265-272
- ISSN
- 1573-403X (ISSN-L)
- PMC
- PMC3492810
- OpenAlex
- W1988755056
- Cited by
- 63
- References
- 94
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 3 · 2020: 4 · 2019: 7 · 2018: 10 · 2017: 6 · 2016: 5 · 2015: 7 · 2014: 11 · 2013: 3 · 2012: 1
- FWCI
- 0.76
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Current Cardiology Reviews (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Keywords
- atrial fibrillation, obstructive sleep apnea, comorbidities, intrathoracic pressure, autonomic instability, atrial remodeling, continuous positive airway pressure, OSA severity
- MeSH terms
- Atrial Fibrillation, Autonomic Nervous System Diseases, Humans, Inflammation, Pressure, Recurrence, Risk Factors, Sleep Apnea, Obstructive, Continuous Positive Airway Pressure
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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