Clinical Status of Anti-Cancer Agents Derived from Marine Sources

Marine Natural Products: A Source of Novel Anticancer Drugs

Khalifa, S. A. M., Elias, N., Farag, M. A., Chen, L., Saeed, A., Hegazy, M.-E. F., Moustafa, M. S., Abd El-Wahed, A., Al-Mousawi, S. M., Musharraf, S. G., et al. (2019) · Marine Drugs · doi:10.3390/md17090491 · Cited by 555

Marine Natural Products: A New Wave of Drugs?

Montaser, R., & Luesch, H. (2011) · Future Medicinal Chemistry · doi:10.4155/fmc.11.118 · Cited by 457

Marine Sponge Derived Natural Products between 2001 and 2010: Trends and Opportunities for Discovery of Bioactives

Mehbub, M. F., Lei, J., Franco, C. M. M., & Zhang, W. Y. (2014) · Marine Drugs · doi:10.3390/md12084539 · Cited by 425

Marine natural products

Blunt, J. W., Copp, B. R., Munro, M. H. G., Northcote, P. T., & Prinsep, M. R. (2010) · Natural Product Reports · doi:10.1039/b906091j · Cited by 409

Tubulin-Interactive Natural Products as Anticancer Agents

Kingston, D. G. I. (2009) · Journal of Natural Products · doi:10.1021/np800568j · Cited by 341

Antibody Drug Conjugates for Cancer Therapy

Polakis, P. G. (2015) · Pharmacological Reviews · doi:10.1124/pr.114.009373 · Cited by 315

Biosynthesis of polyketides by trans-AT polyketide synthases

Piel, J. (2010) · Natural Product Reports · doi:10.1039/b816430b · Cited by 304

Natural products for treating colorectal cancer: A mechanistic review

Huang, X., Yang, Z., Xie, Q., Zhang, Z., Zhang, H., & Ma, J. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.109142 · Cited by 233

Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy

Chen, H., Lin, Z., Arnst, K. E., Miller, D. D., & Li, W. (2017) · Molecules · doi:10.3390/molecules22081281 · Cited by 221

Current scenario of peptide-based drugs: the key roles of cationic antitumor and antiviral peptides

Mulder, K. C. L., de Lima, L. A., Miranda, V. D. J., Dias, S. C., & Franco, O. L. (2013) · Frontiers in Microbiology · doi:10.3389/fmicb.2013.00321 · Cited by 212

Biosynthesis, asymmetric synthesis, and pharmacology, including cellular targets, of the pyrrole-2-aminoimidazole marine alkaloids

Al‐Mourabit, A., Zancanella, M. A., Tilvi, S., et al. (2011) · Natural Product Reports · doi:10.1039/c0np00013b · Cited by 195

Invertebrate Models for Biomedical Research, Testing, and Education

Wilson-Sanders, S. E. (2011) · ILAR Journal · doi:10.1093/ilar.52.2.126 · Cited by 139

Culturability and Secondary Metabolite Diversity of Extreme Microbes: Expanding Contribution of Deep Sea and Deep-Sea Vent Microbes to Natural Product Discovery

Pettit, R. K. (2010) · Marine Biotechnology · doi:10.1007/s10126-010-9294-y · Cited by 131

Current Screening Methodologies in Drug Discovery for Selected Human Diseases

Lage, O. M., Ramos, M. C., Calisto, R., Almeida, E., Vasconcelos, V. M., & Vicente, F. (2018) · Marine Drugs · doi:10.3390/md16080279 · Cited by 139

The antibody-drug conjugate: an enabling modality for natural product-based cancer therapeutics

Gerber, H., Koehn, F. E., & Abraham, R. T. (2013) · Natural Product Reports · doi:10.1039/c3np20113a · Cited by 97

Microtubule-stabilizing agents: New drug discovery and cancer therapy

Zhao, Y., Mu, X. L., & Du, G. (2015) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2015.12.006 · Cited by 83

Marine Antitumor Peptide Dolastatin 10: Biological Activity, Structural Modification and Synthetic Chemistry

Gao, G., Wang, Y., Hua, H., Li, D., & Tang, C. (2021) · Marine Drugs · doi:10.3390/md19070363 · Cited by 88

Recent Advances in Small Peptides of Marine Origin in Cancer Therapy

Zhang, Q., Liu, Z.-D., Wang, Z., Wang, T., Wang, N., Wang, N., Zhang, B., & Yu-fen, Z. (2021) · Marine Drugs · doi:10.3390/md19020115 · Cited by 76

Extract from the Zooxanthellate Jellyfish Cotylorhiza tuberculata Modulates Gap Junction Intercellular Communication in Human Cell Cultures

Leone, A., Lecci, R. M., Durante, M., & Piraino, S. (2013) · Marine Drugs · doi:10.3390/md11051728 · Cited by 73

Origins and Bioactivities of Natural Compounds Derived from Marine Ascidians and Their Symbionts

Dou, X., & Dong, B. (2019) · Marine Drugs · doi:10.3390/md17120670 · Cited by 72

Design, synthesis and biological evaluation of novel imidazole-chalcone derivatives as potential anticancer agents and tubulin polymerization inhibitors

Oskuei, S. R., Mirzaei, S., Jafari-Nik, M. R., et al. (2021) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2021.104904 · Cited by 70

Microtubule-Stabilizing Drugs from Marine Sponges: Focus on Peloruside A and Zampanolide

Miller, J. H., Singh, A. J., & Northcote, P. T. (2010) · Marine Drugs · doi:10.3390/md8041059 · Cited by 67

New Perspectives on Innovative Drug Discovery: An Overview

Pan, S. Y., Pan, S. L., Yu, Z., Ma, D., Chen, S., Fong, W. F., Han, Y., & Ko, K. (2010) · Journal of Pharmacy & Pharmaceutical Sciences · doi:10.18433/j39w2g · Cited by 65

Marine Mollusk‐Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance

Ciavatta, M. L., Lefranc, F., Carbone, M., Mollo, E., Gavagnin, M., Betancourt, T., Dasari, R., Kornienko, A., & Robert Kiss, A. (2016) · Medicinal Research Reviews · doi:10.1002/med.21423 · Cited by 67

Biologically active macromolecules: Extraction strategies, therapeutic potential and biomedical perspective

Bilal, M., & Iqbal, H. M. N. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.02.037 · Cited by 62

Marine Compounds and Cancer: Where Do We Stand?

Dyshlovoy, S. A., & Honecker, F. U. (2015) · Marine Drugs · doi:10.3390/md13095657 · Cited by 56

Manoalide Preferentially Provides Antiproliferation of Oral Cancer Cells by Oxidative Stress-Mediated Apoptosis and DNA Damage

Wang, H., Tang, J., Wang, Y., et al. (2019) · Cancers · doi:10.3390/cancers11091303 · Cited by 51

Natural product mode of action (MOA) studies: a link between natural and synthetic worlds

Clair, J. J. L. (2010) · Natural Product Reports · doi:10.1039/b909989c · Cited by 48

Bioactive Compounds from Marine Heterobranchs

Àvila, C., & Angulo‐Preckler, C. (2020) · Marine Drugs · doi:10.3390/md18120657 · Cited by 48

Highly diastereoselective total synthesis of the anti-tumoral agent (±)-Spisulosine (ES285) from a Morita–Baylis–Hillman adduct

Amarante, G. W., Cavallaro, M., & Coelho, F. (2010) · Tetrahedron Letters · doi:10.1016/j.tetlet.2010.02.169 · Cited by 41

Marine-Derived Natural Lead Compound Disulfide-Linked Dimer Psammaplin A: Biological Activity and Structural Modification

Jing, Q., Hu, X., Ma, Y.-Z., Mu, J., Liu, W., Xu, F., Li, Z., Bai, J., Hua, H., & Li, D. (2019) · Marine Drugs · doi:10.3390/md17070384 · Cited by 40

Molecular mechanisms of action of Trehalose in cancer: A comprehensive review

Chaitanya, N. S. N., Devi, A., Sahu, S., & Alugoju, P. (2021) · Life Sciences · doi:10.1016/j.lfs.2020.118968 · Cited by 37

Marine natural products

Hill, R. A. (2009) · Annual Reports Section B (Organic Chemistry) · doi:10.1039/b822053k · Cited by 38

Polyketide β-Branching in Bryostatin Biosynthesis: Identification of Surrogate Acetyl-ACP Donors for BryR, an HMG-ACP Synthase

Buchholz, T. J., Rath, C. M. B., Lopanik, N. B., Gardner, N. P., Håkansson, K., & Sherman, D. H. (2010) · Chemistry & Biology · doi:10.1016/j.chembiol.2010.08.008 · Cited by 37

The Phylum Bryozoa: From Biology to Biomedical Potential

Ciavatta, M. L., Lefranc, F., Vieira, L. M., Robert Kiss, A., Carbone, M., van Otterlo, W. A. L., Lopanik, N. B., & Waeschenbach, A. (2020) · Marine Drugs · doi:10.3390/md18040200 · Cited by 36

Diastereoselective synthesis and bioactivity of long-chain anti-2-amino-3-alkanols

Chen, B., Yang, L., Ye, J., et al. (2011) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2011.09.010 · Cited by 35

Marine biome-derived secondary metabolites, a class of promising antineoplastic agents: A systematic review on their classification, mechanism of action and future perspectives

Sugumaran, A., Pandiyan, R., Kandasamy, P., Antoniraj, M. G., Navabshan, I., Balasubramaniyan, S., Dharmaraj, S., Chinnaiyan, S. K., Ashokkumar, V., & Ngamcharussrivichai, C. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.155445 · Cited by 36

“Picolog,” a Synthetically-Available Bryostatin Analog, Inhibits Growth of MYC-Induced LymphomaIn Vivo

DeChristopher, B. A., Fan, A. C., Felsher, D. W., & Wender, P. A. (2012) · Oncotarget · doi:10.18632/oncotarget.438 · Cited by 36

Cultivation-independent approaches to investigate the chemistry of marine symbiotic bacteria

Uria, A. R., & Piel, J. (2009) · Phytochemistry Reviews · doi:10.1007/s11101-009-9127-7 · Cited by 34

Advances in the Study of the Structures and Bioactivities of Metabolites Isolated from Mangrove-Derived Fungi in the South China Sea

Wang, X., Mao, Z.-G., Song, B., Chen, C., Xiao, W., Hu, B., Wang, J., Jiang, X., Zhu, Y., & Wang, H. (2013) · Marine Drugs · doi:10.3390/md11103601 · Cited by 34

Research Progress on bioactive peptides from animal sources: A comprehensive review

Sun, J., Chen, Y., Yang, Y., Chen, H., Zhang, J., Wang, H., Bai, D., Sun, Z., Song, J., & Dai, L. (2025) · Food Chemistry · doi:10.1016/j.foodchem.2025.145006 · Cited by 35

An Approach to the Bis-oxazole Macrocycle of Diazonamides

Zhang, J., & Ciufolini, M. A. (2010) · Organic Letters · doi:10.1021/ol102678j · Cited by 33

Jorunnamycin A from Xestospongia sp. Suppresses Epithelial to Mesenchymal Transition and Sensitizes Anoikis in Human Lung Cancer Cells

Ecoy, G. A. U., Chamni, S., Suwanborirux, K., Chanvorachote, P., & Chaotham, C. (2019) · Journal of Natural Products · doi:10.1021/acs.jnatprod.9b00102 · Cited by 32

Anticancer Effect and Structure-Activity Analysis of Marine Products Isolated from Metabolites of Mangrove Fungi in the South China Sea

Tao, L.-Y., Zhang, J., Liang, Y.-J., Chen, L., Zheng, L.-S., Wang, F., Mi, Y., She, Z., To, K. K. W., Lin, Y., et al. (2010) · Marine Drugs · doi:10.3390/md8041094 · Cited by 31

Optimization of Marine Triterpene Sipholenols as Inhibitors of Breast Cancer Migration and Invasion

Foudah, A. I., Jain, S. K., Busnena, B. A., & Sayed, K. A. E. (2013) · ChemMedChem · doi:10.1002/cmdc.201200516 · Cited by 31

A Shimizu Non‐Aldol Approach to the Formal Total Synthesis of Palmerolide A

Pujari, S. A., Parthasarathy, G., & Kaliappan, K. P. (2011) · Chemistry - An Asian Journal · doi:10.1002/asia.201100429 · Cited by 29

Structural Features Underlying Selective Inhibition of GSK3β by Dibromocantharelline: Implications for Rational Drug Design

Zhang, N., Zhong, R., Yan, H., & Jiang, Y. (2010) · Chemical Biology & Drug Design · doi:10.1111/j.1747-0285.2010.01069.x · Cited by 28

Marine-Derived Metabolites of S-Adenosylmethionine as Templates for New Anti-Infectives

Sufrin, J. R., Finckbeiner, S., & Oliver, C. M. (2009) · Marine Drugs · doi:10.3390/md7030401 · Cited by 27

Asymmetric Synthesis of ES‐285, an Anticancer Agent Isolated from Marine Sources

Allepuz, A. C., Badorrey, R., Diaz-De-Villegas, M. D., et al. (2009) · European Journal of Organic Chemistry · doi:10.1002/ejoc.200900828 · Cited by 27

Finding chemo: the search for marine-based pharmaceutical drugs active against cancer

Indumathy, S., & Dass, C. R. (2013) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.12097 · Cited by 26

Anti-Melanogenic Property of Geoditin A in Murine B16 Melanoma Cells

Cheung, F. W. K., Guo, J., Ling, Y. H., et al. (2012) · Marine Drugs · doi:10.3390/md10020465 · Cited by 26

3‐(2,4‐Dimethoxybenzylidene)‐anabaseine: A promising candidate drug for Alzheimer's disease?

Zawieja, P. P., Kornprobst, J., & Métais, P. (2012) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/j.1447-0594.2011.00827.x · Cited by 25

Natural products as probes in pharmaceutical research

Schmitt, E. K., Hoepfner, D., & Krastel, P. (2015) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/s10295-015-1691-9 · Cited by 24

Harmful and beneficial properties of cyanotoxins: Two sides of the same coin

Ricciardelli, A., Pollio, A., Costantini, M., & Zupo, V. (2023) · Biotechnology Advances · doi:10.1016/j.biotechadv.2023.108235 · Cited by 26

Asymmetric total syntheses of spisulosine, its diastereo- and regio-isomers

Dinda, S. K., Das, S. K., & Panda, G. (2010) · Tetrahedron · doi:10.1016/j.tet.2010.09.018 · Cited by 23

Separacenes A–D, Novel Polyene Polyols from the Marine Actinomycete, Streptomyces sp.

Bae, M., Kim, H., Shin, Y., Kim, B., Lee, S. K., Oh, K., Shin, J., & Oh, D. (2013) · Marine Drugs · doi:10.3390/md11082882 · Cited by 23

In silico comparison of marine, terrestrial and synthetic compounds using ChemGPS-NP for navigating chemical space

Muigg, P., Rosén, J., Bohlin, L., & Backlund, A. (2013) · Phytochemistry Reviews · doi:10.1007/s11101-012-9256-2 · Cited by 22

Advances in the Total Syntheses of Complex Indole Natural Products

Fu, L. (2010) · Topics in heterocyclic chemistry · doi:10.1007/7081_2010_49 · Cited by 22

A New in Vitro Anti-Tumor Polypeptide Isolated from Arca inflata

Xu, J., Chen, Z., Song, L., Chen, L., Zhu, J., Lv, S., & Yu, R. (2013) · Marine Drugs · doi:10.3390/md11124773 · Cited by 21

Optimization, pharmacophore modeling and 3D-QSAR studies of sipholanes as breast cancer migration and proliferation inhibitors

Foudah, A. I., Sallam, A. A., Akl, M. R., & Sayed, K. A. E. (2013) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2013.11.039 · Cited by 21

Discovery and preliminary structure-activity relationship of the marine natural product manzamines as herpes simplex virus type-1 inhibitors

Palem, J. R., Mudit, M., Hsia, S. V., & Sayed, K. A. E. (2016) · Zeitschrift für Naturforschung C · doi:10.1515/znc-2016-0080 · Cited by 21

Extremophiles and their application to veterinary medicine

Irwin, J. A. (2010) · Environmental Technology · doi:10.1080/09593330.2010.484073 · Cited by 22

A New Scaffold of an Old Protein Fold Ensures Binding to the Bisintercalator Thiocoraline

Biswas, T., Zolova, O. E., Lombó, F., et al. (2010) · Journal of Molecular Biology · doi:10.1016/j.jmb.2010.01.053 · Cited by 20

Analogues of the marine alkaloids oroidin, clathrodin, and hymenidin induce apoptosis in human HepG2 and THP-1 cancer cells

Tomašič, T., Nabergoj, D., Vrbek, S., et al. (2014) · MedChemComm · doi:10.1039/c4md00286e · Cited by 19

Impact of Marine Drugs on Cytoskeleton-Mediated Reproductive Events

Silvestre, F., & Tosti, E. (2010) · Marine Drugs · doi:10.3390/md8040881 · Cited by 19

Novel Bioactive Peptides from Cyanobacteria

Arif, J. M., Farooqui, A., Siddiqui, M. H., Al-Karrawi, M., Al-Hazmi, A., & Al‐Sagair, O. A. (2012) · Studies in natural products chemistry · doi:10.1016/b978-0-444-53836-9.00022-0 · Cited by 17

Antineoplastic Agents. 590. X-ray Crystal Structure of Dolastatin 16 and Syntheses of the Dolamethylleuine and Dolaphenvaline Units

Pettit, G. R., Smith, T. H., Xu, J., Herald, D. L., Flahive, E. J., Anderson, C. R., Belcher, P. E., & KNIGHT, J. C. (2011) · Journal of Natural Products · doi:10.1021/np100877h · Cited by 17

Hydrobiological Aspects of Fatty Acids: Unique, Rare, and Unusual Fatty Acids Incorporated into Linear and Cyclic Lipopeptides and Their Biological Activity

Dembitsky, V. M. (2022) · Hydrobiology · doi:10.3390/hydrobiology1030024 · Cited by 17

Xenicane Natural Products: Biological Activity and Total Synthesis

Betschart, L., & Altmann, K. (2015) · Current Pharmaceutical Design · doi:10.2174/1381612821666151002112607 · Cited by 16

Cytotoxicity of actinomycetes associated with the ascidian Eudistoma vannamei (Millar, 1977), endemic of northeastern coast of Brazil

Jimenez, P. C., Ferreira, E. G., Araújo, L. A., Guimarães, L. A., Sousa, T. S., Pessoa, O. D. L., Lotufo, T. M. D. C., & Costa-Lotufo, L. V. (2017) · Latin American Journal of Aquatic Research · doi:10.3856/vol41-issue2-fulltext-12 · Cited by 18

Geoditin A Induces Oxidative Stress and Apoptosis on Human Colon HT29 Cells

Cheung, F. W. K., Li, C., Che, C., et al. (2010) · Marine Drugs · doi:10.3390/md8010080 · Cited by 16

Targets and Therapeutic Properties

Beeton, C. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-385095-9.00064-6 · Cited by 15

Marine Sponge-Derived/Inspired Drugs and Their Applications in Drug Delivery Systems

Ramanjooloo, A., Andersen, R. J., & Bhaw‐Luximon, A. (2021) · Future Medicinal Chemistry · doi:10.4155/fmc-2020-0123 · Cited by 15

Marine-derived pipeline anticancer natural products: a review of their pharmacotherapeutic potential and molecular mechanisms

Ali‐Seyed, M., & Ayesha, S. (2021) · Future Journal of Pharmaceutical Sciences · doi:10.1186/s43094-021-00350-z · Cited by 18

Antiproliferative effect of flavomannin-6,6′-dimethylether from Tricholoma equestre on Caco-2 cells

Pachón-Peña, G., Reyes‐Zurita, F. J., Deffieux, G., et al. (2009) · Toxicology · doi:10.1016/j.tox.2009.08.009 · Cited by 14

4-Amino-2-arylamino-5-indoloyl/cinnamoythiazoles, analogs of topsentin-class of marine alkaloids, induce apoptosis in HeLa cells

Juneja, M., Vanam, U., Sripriya, P., et al. (2013) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2013.02.032 · Cited by 13

Synthesis and use of dioxime ligands for treatment of leukemia and colon cancer cells

Babahan, I., Özmen, A., & Aslan, K. (2017) · Applied Organometallic Chemistry · doi:10.1002/aoc.3752 · Cited by 13

Synthesis and anti-tumor activity of marine alkaloids

Zhou, S., Huang, G., & Chen, G. (2021) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2021.128009 · Cited by 12

The Configuration-Dependent Anti-Leukemic Effect of Manoalide Stereoisomers: Reignite Research Interest in these Sponge-Derived Sesterterpenoids

Lai, K.-H., Peng, B., Hsu, Y., et al. (2021) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2021.105150 · Cited by 11

Pharmacokinetics of Jaspine B and Enhancement of Intestinal Absorption of Jaspine B in the Presence of Bile Acid in Rats

Choi, M., Lee, J., Nam, S., et al. (2017) · Marine Drugs · doi:10.3390/md15090279 · Cited by 11

Oxidative-Stress-Mediated ER Stress Is Involved in Regulating Manoalide-Induced Antiproliferation in Oral Cancer Cells

Peng, S., Tang, J., Lan, T., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043987 · Cited by 10

Potential Role of Marine Species-Derived Bioactive Agents in the Management of SARS-CoV-2 Infection

Asif, M., Saleem, M., Yaseen, H. S., Yehya, A. H. S., Saadullah, M., Zubair, H. M., Oon, C. E., Khaniabadi, P. M., Khalid, S. H., Khan, I. U., et al. (2021) · Future Microbiology · doi:10.2217/fmb-2021-0024 · Cited by 10

New Medical Applications of Plant Secondary Metabolites

Heilmann, J. (2010) · Wiley-Blackwell eBooks · doi:10.1002/9781444318876.ch5 · Cited by 10

Total synthesis of marine natural products separacenes A and B

Das, S., & Goswami, R. K. (2017) · Organic & Biomolecular Chemistry · doi:10.1039/c7ob00345e · Cited by 9

From Sea Sponge to Clinical Trials: Starting the Journey of the Novel Compound PM742

Cruz, P. G., Fernández, R., Rodríguez‐Acebes, R., et al. (2024) · Marine Drugs · doi:10.3390/md22080339 · Cited by 8

Synthesis of a triterpene-spermidine conjugate

Kazakova, O. B., Giniyatullina, G. V., Medvedeva, N. I., et al. (2012) · Russian Journal of Organic Chemistry · doi:10.1134/s1070428012100181 · Cited by 8

Girolline is a sequence context-selective modulator of eIF5A activity

Schneider‐Poetsch, T., Dang, Y., Iwasaki, W., Arata, M., Shichino, Y., Al‐Mourabit, A., Moriou, C., Romo, D., Liu, J. O., Ito, T., et al. (2025) · Nature Communications · doi:10.1038/s41467-024-54838-2 · Cited by 7

Antiproliferation Effects of Marine-Sponge-Derived Methanol Extract of Theonella swinhoei in Oral Cancer Cells In Vitro

Shiau, J., Chuang, Y.-T., Tang, J., Chen, S., Hou, M., Jeng, J., Cheng, Y., & Chang, H. (2022) · Antioxidants · doi:10.3390/antiox11101982 · Cited by 7

Natural Anticancer Compounds and Their Derivatives in Clinical Trials

Veerabhadrappa, B., Sudharshan, S. J., & Dyavaiah, M. (2017) · Springer eBooks · doi:10.1007/978-981-10-8216-0_3 · Cited by 8

Natural Product Cytotoxins as Payloads for Antibody Drug Conjugates

Koehn, F. E. (2012) · Springer eBooks · doi:10.1007/978-1-4614-4654-5_5 · Cited by 7

Pharmacological Applications of Metabolites of Mangrove Endophytes: A Review

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Characterization of Bioactive Compounds from the Red Sea Tunicate- Derived Fungus Penicillium commune DY004

Youssef, D. T. A., Shaala, L. A., Almohammadi, A. M., et al. (2021) · Letters in Organic Chemistry · doi:10.2174/1570178618666210617112441 · Cited by 5

Identification and validation of a novel anoikis‐related prognostic model for prostate cancer

Zhang, P., Lv, W., Luan, Y., Cai, W., Min, X., & Feng, Z. (2024) · Molecular Genetics & Genomic Medicine · doi:10.1002/mgg3.2419 · Cited by 5

Marine Compounds as a Starting Point to Drugs

Rubiolo, J. A., Alonso, E., & Cagide, E. (2014) · CRC Press eBooks · doi:10.1201/b16662-48 · Cited by 5

Auristatin Payloads for Antibody–Drug Conjugates (ADCs)

Doronina, S. O., & Senter, P. D. (2019) · Royal Society of Chemistry eBooks · doi:10.1039/9781788012898-00073 · Cited by 5

Discovery and Computer-Aided Drug Design Studies of the Anticancer Marine Triterpene Sipholanes as Novel P-gp and Brk Modulators

Foudah, A. I., Sallam, A. A., & Sayed, K. A. E. (2014) · Springer eBooks · doi:10.1007/978-3-319-07145-9_26 · Cited by 5

Synthesis of Amino Core Compounds of Galactosyl Phytosyl Ceramide Analogs for Developing iNKT-Cell Inducers

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Colorectal cytotoxic activities of phenolic constituents isolated from Euphorbia pseudocactus cultivated in Egypt

Ismail, M., Hassan, M. H. A., Zaki, M., et al. (2022) · Journal of Applied Pharmaceutical Science · doi:10.7324/japs.2022.121111 · Cited by 4

Synthesis of an Acyclic C1–C11 Fragment of Peloruside B

Zang, Q., Gulab, S. A., Stocker, B. L., Baars, S. M., & Hoberg, J. O. (2011) · European Journal of Organic Chemistry · doi:10.1002/ejoc.201100053 · Cited by 4

Коммуникaтивно- прaгмaтический aнaлиз дипломaтических бумaг (нa основе вербaльных нот)

Кaмирдиновa, Н., & Кaлиевa, Ш. С. (2018) · DOAJ (DOAJ: Directory of Open Access Journals)

Susquehanna Chorale Spring Concert "Roots and Wings"

Hawkins, D. (2017)

A GEOMETRIC MEAN IN THE FURUTA INEQUALITY

Fujii, M., & Nakamoto, R. (2002) · Scientiae mathematicae Japonicae · Cited by 15

Synthesis and in vitro cytotoxicity of diastereoisomerically modified dolastatin 15 analogues

Roux‐Dalvai, F., Galéotti, N., Poncet, J., et al. (1994) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(01)80540-0 · Cited by 9

Revised absolute stereochemistry of natural kulokekahilide-2

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