The DOI matches its Crossref record; 184 of the 185 references it cites were found in a registry or an index.
Is Fast Food Addictive?
Abstract
Studies of food addiction have focused on highly palatable foods. While fast food falls squarely into that category, it has several other attributes that may increase its salience. This review examines whether the nutrients present in fast food, the characteristics of fast food consumers or the presentation and packaging of fast food may encourage substance dependence, as defined by the American Psychiatric Association. The majority of fast food meals are accompanied by a soda, which increases the sugar content 10-fold. Sugar addiction, including tolerance and withdrawal, has been demonstrated in rodents but not humans. Caffeine is a "model" substance of dependence; coffee drinks are driving the recent increase in fast food sales. Limited evidence suggests that the high fat and salt content of fast food may increase addictive potential. Fast food restaurants cluster in poorer neighborhoods and obese adults eat more fast food than those who are normal weight. Obesity is characterized by resistance to insulin, leptin and other hormonal signals that would normally control appetite and limit reward. Neuroimaging studies in obese subjects provide evidence of altered reward and tolerance. Once obese, many individuals meet criteria for psychological dependence. Stress and dieting may sensitize an individual to reward. Finally, fast food advertisements, restaurants and menus all provide environmental cues that may trigger addictive overeating. While the concept of fast food addiction remains to be proven, these findings support the role of fast food as a potentially addictive substance that is most likely to create dependence in vulnerable populations.
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“the response to foods in humans, is far more complex, and is influenced not just by its palatability but also by its availability (the patterns of restriction plus overeating, referred to as the eating topography (16)), its visual appeal, economics and incentives (i.e., ‘super sizing’ offers, soda combos), social routines for eating, alternative reinforcement and advertisements (17).”
From Obesity and addiction: Neurobiological overlaps (2013) · cites this paper as [17]
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“Unhealthy home food availability increased takeaway diet pattern, further influencing the consumption of SSBs (68).”
BackgroundSilberman, M. S., Moreno-Altamirano, L., Hernández-Montoya, D., Capraro, S., García-García, J. J., & Soto-Estrada, G. (2016) · International Journal of Food Sciences and Nutrition · doi:10.1080/09637486.2016.1221384 · Cited by 9
“In addition, sugar alters the hunger–satiety cycle, producing dependency and provoking homeostatic problems in the body (Garber & Lustig 2011).”
BackgroundObesity, metabolic syndrome, and disorders of energy balance
Weiss, R., & Lustig, R. H. (2014) · Elsevier eBooks · doi:10.1016/b978-1-4557-4858-7.00031-7 · Cited by 9
Are Eating Disorders Addictions?
Brewerton, T. D. (2014) · Springer eBooks · doi:10.1007/978-3-642-45378-6_13 · Cited by 9
Eating ourselves to death: How food is a drug and what food abuse costs
Robinson, M. B. (2022) · Drug Science Policy and Law · doi:10.1177/20503245221112577 · Cited by 8
Malhotra, A., Schofield, G., & Lustig, R. H. (2018) · Journal of Metabolic Health · doi:10.4102/jir.v3i1.39 · Cited by 8
Qualitative Approaches to the Study of Substance and Behavioral Addictions
Simpson, K. A., & Bluthenthal, R. N. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.013 · Cited by 10
The Role of High Salt Intake in the Development and Progression of Diverse Diseases
Kompanowska‐Jezierska, E., & Olszyński, K. H. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-811442-1.00013-4 · Cited by 7
Ishak, Z., Fin, L. S., Ibrahim, W. A. H. W., Zain, F. M., Yahya, A., Selamat, R., Jalaludin, M. Y., & Mokhtar, A. H. (2022) · SAGE Open · doi:10.1177/21582440221086604 · Cited by 7
“The high fat and salt content in fast food may cause it to become potentially addictive (Garber & Lustig, 2011).”
BackgroundInfluentialValmórbida, J. L., Baratto, P. S., Leffa, P. D. S., Sangalli, C. N., da Silva, J. A., & Vítolo, M. R. (2023) · Nutrition Research · doi:10.1016/j.nutres.2023.05.012 · Cited by 8
Does Sugar Addiction Really Cause Obesity?
Peters, A. (2012) · Frontiers in Neuroenergetics · doi:10.3389/fnene.2011.00011 · Cited by 6
Substance and Behavioral Addictions Assessment Instruments
Grigsby, T. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.012 · Cited by 6
Snacking and anxiety during the coronavirus disease (COVID-19) pandemic: A prospective cohort study
Curtin, E. L., Johnson, L., Salway, R., & Hinton, E. C. (2023) · Appetite · doi:10.1016/j.appet.2023.106491 · Cited by 5
“…snacks not sweet snacks (Paans et al., 2019; Sadler et al., 2021), therefore it could be that such traits exert a more potent effect on foods high in salt that have addictive properties (Garber & Lustig, 2011), a pattern that could not be ascertained through our measure of overall snacking.”
Ren, J., Yin, K., Fan, G., Xiao, L., Zhao, L., Li, Z., Zhang, L., Xie, D., Pan, S., & Yuan, F. (2020) · Food & Function · doi:10.1039/d0fo02214d · Cited by 7
The battle over “food addiction”
Lustig, R. H. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1621742 · Cited by 4
“Fast food contains four components whose hedonic properties have been examined: salt, fat, caffeine, and sugar (48).”
Endocrine hypertension: What is new?
Koch, C. A. (2012) · Revista Portuguesa de Endocrinologia Diabetes e Metabolismo · doi:10.1016/s1646-3439(12)70010-x · Cited by 4
de Silva, P. N. (2019) · Medical Hypotheses · doi:10.1016/j.mehy.2019.109469 · Cited by 4
Prevention and Treatment of Sex Addiction
Reid, R. C., Grubbs, J. B., & Kraus, S. W. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.025 · Cited by 4
Bukolt, K. F., Ramírez, N. C., Saenz, A., Mirza, K., Bhaduri, S., & Navder, K. P. (2019) · doi:10.35248/2157-7110.19.10.804 · Cited by 4
Muda, R., Sawicki, P., & Ginszt, M. (2021) · PLoS ONE · doi:10.1371/journal.pone.0255484 · Cited by 4
“On the deeper level, such a food rather does not produce crave to eat it once again or will not lead to overeating (in contrast to fast foods that might create addiction [32]).”
Background
Metadata
- Authors
- K. Garber, A., & H. Lustig, R.
- Venue
- Current Drug Abuse Reviewse
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2011-09-01
- Volume
- 4
- Issue
- 3
- Pages
- 146-162
- ISSN
- 1874-4737 (ISSN-L)
- OpenAlex
- W2092089565
- Cited by
- 143
- References
- 185
- Citations by year
- 2026: 2 · 2025: 4 · 2023: 8 · 2022: 5 · 2021: 12 · 2020: 50 · 2019: 5 · 2018: 6 · 2017: 3 · 2016: 9 · 2015: 9 · 2014: 11 · 2013: 11 · 2012: 6
- FWCI
- 10.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Drug Abuse Reviews (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Center for Research Resources (UL1RR024131)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Keywords
- food addiction, sugar addiction, caffeine dependence, obesity, insulin resistance, leptin resistance, food advertising, environmental cues, stress, dieting, highly palatable food, substance dependence
- MeSH terms
- Animals, Caffeine, Cues, Diet, Reducing, Dietary Fats, Humans, Stress, Psychological, Behavior, Addictive, Sodium Chloride, Dietary, Dietary Sucrose, Substance-Related Disorders, Fast Foods
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