The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Home Blood Pressures Are of Greater Prognostic Value than Hemodialysis Unit Recordings
Abstract
BACKGROUND AND OBJECTIVES: Although ambulatory BP recordings are found to be superior to dialysis unit recordings in predicting outcomes, ambulatory BP are difficult to obtain in the day-to-day treatment of hemodialysis patients. Home BP agree well with ambulatory BP, but the prognostic significance of home BP recordings is unknown in hemodialysis patients. This study ascertained the role of home BP in predicting all-cause and cardiovascular mortality. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: A prospective cohort study was conducted in 150 patients who were on chronic hemodialysis dialyzing at four university-affiliated units. BP was self-measured at home for 1 wk, for an interdialytic interval by ambulatory recording, and by "routine" and standardized methods in the dialysis unit for 2 wk. Patients were followed for a median of 24 mo to assess the end points of all-cause and cardiovascular mortality. RESULTS: Cardiovascular death occurred in 26 (17%) patients and death in 46 (31%) patients. A 1-SD increase in systolic BP increased the risk for death by 1.35 (95% CI 0.99 to 1.84) and in diastolic BP by 1.40 (95% CI 1.03 to 1.93) for home BP and between 0.97 to 1.19 (P > 0.20) for all-cause mortality for dialysis unit BP recording. A dose-response relationship between increasing quartiles of home BP and all-cause mortality and cardiovascular mortality was seen. CONCLUSIONS: Self-measured systolic BP of 125 to 145 mmHg and of 115 to 125 mmHg by ambulatory BP is associated with the best prognosis in hemodialysis patients.
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“Patients with CKD on haemodialysis are profoundly different from patients with CKD who are not on dialysis; this is so because of varying states of volume excess among patients and volume accumulation in the interdialytic period [204–206].”
Citations
Cites
Agarwal, R., Peixoto, A. J., Santos, S. F. F., & Zoccali, C. (2006) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.01891105 · Cited by 245
Self-citationAgarwal, R., & Andersen, M. J. (2006) · Kidney International · doi:10.1038/sj.ki.5000081 · Cited by 184
Self-citationHome blood pressure monitoring improves the diagnosis of hypertension in hemodialysis patients
Agarwal, R., Andersen, M. J., Bishu, K., & Saha, C. (2006) · Kidney International · doi:10.1038/sj.ki.5000145 · Cited by 175
Self-citationHome Blood Pressure Monitoring in CKD
Andersen, M. J., Khawandi, W., & Agarwal, R. (2005) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2005.02.015 · Cited by 123
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Items 201–222 of 222
Diawara, F., Fumeron, C., Duflot, L., Tia, M. W., & Bobrie, G. (2022) · Néphrologie & Thérapeutique · doi:10.1016/j.nephro.2021.10.004
Die Bedeutung der Langzeit-Blutdruckmessung bei Patienten mit Nierenkrankheiten
Reshetnik, A. (2021) · Dialyse aktuell · doi:10.1055/a-1557-4989
Shamy, O. E., & Golper, T. (2021) · Nephrology Self-Assessment Program · doi:10.1681/nsap.2021.20.1.1
Cohen, J. (2021) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2021.06.010
Kraus, M. A., & Weinhandl, E. D. (2018) · Elsevier eBooks · doi:10.1016/b978-0-323-52978-5.00028-8 · Cited by 1
Alabeidi, F., Alosaimi, F. M., Alsaeed, S. A., Alshammari, I. F., Shamry, M. H. A., Alamri, . M. M., Aljehani, M. R., Alsulaiman, A. I., Almutairi, F. M. H., Almzairie, K. A., et al. (2020) · International Journal of Health Sciences · doi:10.53730/ijhs.v4ns1.15263
“A meta-analysis confirmed the poor correlation between pre/postdialysis BP and ambulatory BP measurements (34), with cohort studies indicating that home BP readings are superior in predicting all-cause mortality compared to peridialysis BP measurements (35, 36).”
ResultRyu, J., Cha, R.-H., Lee, H., Kim, Y. S., Lee, J. P., Song, Y., Kim, S. G., & Kim, S. J. (2019) · Electrolytes & Blood Pressure · doi:10.5049/ebp.2019.17.2.36
Agarwal, R. (2018) · doi:10.7912/c2p948
Self-citationGohlisch, C., & van der Giet, M. (2018) · Dialyse aktuell · doi:10.1055/a-0581-1256
“Da die Patienten ohnehin i. d. R. 3-mal wöchentlich zur Dialysetherapie in die Praxis kommen, hat sich die peridialytische Blutdruckmessung als einfach zu praktizieren etabliert.”
BackgroundInfluentialCardiovascular Disease in Dialysis Patients
Jegatheesan, D., Yang, W.-L., Krishnasamy, R., Hawley, C., & Johnson, D. (2017) · InTech eBooks · doi:10.5772/intechopen.70362
“Home BP recordings, including ABPM and self-measured readings have been shown to be greater predictors of all-cause and cardiovascular mortality than haemodialysis unit recordings [24].”
BackgroundReply to: On Poor Agreement Between Dialysis Unit and Ambulatory Blood Pressures
Liu, W.-J., Dai, C.-S., & Yang, J.-W. (2015) · The Journal of Clinical Hypertension · doi:10.1111/jch.12487
“Given the inconvenience and cost of ambulatory BP monitoring, home BP has been shown to be a reliable and feasible option for BP management in dialysis patients.(3)”
MethodCorrelates of Blood Pressure and Predictors of Cardiovascular Mortality in Haemodialysis Patients
Vernaglione, L., Nosella, V., & Chimienti, S. (2010) · High Blood Pressure & Cardiovascular Prevention · doi:10.2165/11311820-000000000-00000
Hypertension in End-Stage Renal Disease
Gupta, S., & Liebman, S. (2020) · Hypertension Journal · doi:10.15713/ins.johtn.0177
“Over a median 24 months of follow-up, higher BPs at home and through ABPM measurements predicted all-cause mortality, whereas in-center measurements did not.[22] In a separate analysis, Agarwal also showed that home systolic BPs and ABPM systolic BPs predicted mortality after a median 29-month follow-up period.”
BackgroundBurnier, M., Viazzi, F. C., Leoncini, G., Wuerzner, G., & Pontremoli, R. (2020) · Updates in hypertension and cardiovascular protection · doi:10.1007/978-3-030-45562-0_1 · Cited by 3
Hypertension in Dialysis Patients: Clinical Epidemiology, Pathogenesis, Diagnosis, and Treatment
Sarafidis, P. A., Georgianos, P. I., & Zoccali, C. (2018) · Updates in hypertension and cardiovascular protection · doi:10.1007/978-3-319-59918-2_24
Naruszewicz, R., & Manitius, J. (2017) · doi:10.5603/ah.2017.0006
“Our findings reveal the predominant role that SBP plays in the development of organ-specific complications [12, 13].”
BackgroundHypertension in End-Stage Renal Disease: Dialysis
Schaefer, F. S. (2017) · Springer eBooks · doi:10.1007/978-3-319-31420-4_48-1
Hypertension in the Dialysis Patient
Sinha, A. D. (2016) · Springer eBooks · doi:10.1007/978-1-4939-6436-9_7
Central BP Monitoring, Home BP Monitoring, Ambulatory BP Monitoring in CKD
Cohen, D. L., Huan, Y., & Townsend, R. R. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1982-6_2
“Interdialytic BP readings done at home in dialysis patients outside the dialysis unit have been shown to predict target organ damage, including left ventricular hypertrophy (LVH) and mortality [52–57].”
BackgroundHypertension in chronic kidney disease
Chaudhary, K., Buddineni, J., Botdorf, J., & Whaley-Connell, A. (2012) · Humana Press eBooks · doi:10.1007/978-1-60327-357-2_4
Weir, M. R., & Portocarrero, M. (2010) · Humana Press eBooks · doi:10.1007/978-1-60327-963-5_8
“Others have demonstrated that activated vitamin D has antiproteinuric effects in patients with nephropathy ( 65 ), despite concomitant use of renal angiotensin system blockers.”
Background
Metadata
- Authors
- Alborzi, P., Patel, N., & Agarwal, R.
- Affiliations
- Richard L. Roudebush VA Medical Center (US)
- Corresponding author
- Agarwal, Rajiv
- ORCID
- Agarwal, Rajiv
- Venue
- Clinical Journal of the American Society of Nephrology
- Published
- 2007-11
- Volume
- 2
- Issue
- 6
- Pages
- 1228-1234
- ISSN
- 1555-9041 (ISSN-L)
- OpenAlex
- W2128457806
- Cited by
- 248
- References
- 0
- Citations by year
- 2026: 3 · 2025: 12 · 2024: 12 · 2023: 15 · 2022: 10 · 2021: 14 · 2020: 16 · 2019: 16 · 2018: 15 · 2017: 16 · 2016: 24 · 2015: 14 · 2014: 11 · 2013: 9 · 2012: 18
- FWCI
- 6.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Journal of the American Society of Nephrology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5t32dk062711-05)
- U.S. Public Health Service (5R01-063020)
- National Institute of Diabetes and Digestive and Kidney Diseases (5T32DK062711)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Nephrology › Dialysis and Renal Disease Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Keywords
- home blood pressure, hemodialysis, ambulatory blood pressure monitoring, cardiovascular mortality, all-cause mortality, prognostic value, self-measured blood pressure, interdialytic interval, systolic blood pressure, diastolic blood pressure, dose-response relationship
- MeSH terms
- Adult, Aged, Blood Pressure Determination, Cross-Sectional Studies, Female, Renal Dialysis, Humans, Male, Middle Aged, Prognosis, Prospective Studies, Self Care, Cohort Studies, Blood Pressure Monitoring, Ambulatory
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