The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
HLA-B Locus in Caucasian Patients with Carbamazepine hypersensitivity
Abstract
BACKGROUND: A strong pharmacogenetic association has been reported in Chinese patients between human leukocyte antigen (HLA)-B*1502 and carbamazepine (CBZ)-induced Stevens-Johnson syndrome (SJS). METHODS: We have genotyped the HLA-B alleles in 56 Caucasian patients with varying severities of CBZ hypersensitivity and 43 controls on CBZ without adverse effects. RESULTS: None of our patients (including two with blistering skin rashes) were positive for the HLA-B*1502 allele. HLA-B*0702 allele may protect against severe CBZ hypersensitivity but warrants further study. Of secondary interest, the correlation between HLA-B*0801 and HLA-DR3, DQ2 and TNF -308 alleles (on the ancestral haplotype 8.1) is consistent with our previous findings. CONCLUSION: HLA-B*1502 does not seem to be a marker for all forms of CBZ-induced hypersensitivity in a Caucasian population.
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A marker for Stevens–Johnson syndrome
Chung, W.-H., Hung, S.-I., Hong, H.-S., Hsih, M.-S., Yang, L.-C., Ho, H.-C., Wu, J.-Y., & Chen, Y.-T. (2004) · Nature · doi:10.1038/428486a · Cited by 1,753
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HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol
Hung, S.-I., Chung, W.-H., Liou, L.-B., Chu, C.-C., Lin, M., Huang, H.-P., Lin, Y.-L., Lan, J.-L., Yang, L.-C., Hong, H.-S., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409500102 · Cited by 1,284
Genetic variations in HLA-B region and hypersensitivity reactions to abacavir
Hetherington, S., Hughes, A. R., Mosteller, M., Shortino, D., Baker, K. L., Spreen, W., Lai, E., Davies, K., Handley, A., Dow, D. J., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08158-8 · Cited by 807
Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions
Hung, S.-I., Chung, W.-H., Jee, S.-H., Chen, W.-C., Chang, Y.-T., Lee, W.-R., Hu, S.-L., Wu, M.-T., Chen, G.-S., Wong, T.-W., et al. (2006) · Pharmacogenetics and Genomics · doi:10.1097/01.fpc.0000199500.46842.4a · Cited by 680
Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism
Sette, A., & Sidney, J. (1999) · Immunogenetics · doi:10.1007/s002510050594 · Cited by 635
Cao, K., Hollenbach, J., Shi, X., Shi, W., Chopek, M., & Fernández-Viña, M. A. (2001) · Human Immunology · doi:10.1016/s0198-8859(01)00298-1 · Cited by 465
Anticonvulsant Hypersensitivity Syndrome
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A marker for Stevens-Johnson syndrome …: ethnicity matters
Lonjou, C., Thomas, L., Borot, N., Ledger, N., de Toma, C., LeLouet, H., Graf, E., Schumacher, M., Hovnanian, A., Mockenhaupt, M., et al. (2006) · The Pharmacogenomics Journal · doi:10.1038/sj.tpj.6500356 · Cited by 401
Cost-effectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity
Hughes, D. A., Vilar, F. J., Ward, C. C., Alfirevic, A., Park, B. K., & Pirmohamed, M. (2004) · Pharmacogenetics · doi:10.1097/00008571-200406000-00002 · Cited by 290
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International Con sensus on drug allergy
Demoly, P., Adkinson, N. F., Brockow, K., Castells, M., Chiriac, A. M., Greenberger, P. A., Khan, D. A., Lang, D. M., Park, H. ‐., Pichler, W., et al. (2014) · Allergy · doi:10.1111/all.12350 · Cited by 935
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Husain, Z., Reddy, B. Y., & Schwartz, R. A. (2013) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2013.01.033 · Cited by 489
Next generation disparities in human genomics: concerns and remedies
Need, A. C., & Goldstein, D. B. (2009) · Trends in Genetics · doi:10.1016/j.tig.2009.09.012 · Cited by 398
Current Perspectives on Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Lerch, M., Mainetti, C., Terziroli Beretta-Piccoli, B., & Harr, T. (2018) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-017-8654-z · Cited by 355
Metadata
- Authors
- Alfirevic, A., Jorgensen, A. L., Williamson, P. R., Chadwick, D. W., Park, B. K., & Pirmohamed, M.
- Venue
- Pharmacogenomics
- Publisher
- Informa UK Limited
- Published
- 2006-09
- Volume
- 7
- Issue
- 6
- Pages
- 813-818
- ISSN
- 1462-2416 (ISSN-L)
- 1744-8042
- OpenAlex
- W2118621632
- Cited by
- 264
- References
- 18
- FWCI
- 9.06
- Type
- journal article
- Language
- en
- Open access
- closed
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- Alfirevic, A., Jorgensen, A. L., Williamson, P. R., Chadwick, D. W., Park, B. K., & Pirmohamed, M. (2006). HLA-B Locus in Caucasian Patients with Carbamazepine hypersensitivity. Pharmacogenomics. https://doi.org/10.2217/14622416.7.6.813
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