The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Gold Nanoparticle-Mediated Photothermal Therapy: Current Status and Future Perspective
Abstract
Gold nanoparticles (AuNPs) are attractive photothermal agents for cancer therapy because they show efficient local heating upon excitation of surface plasmon oscillations. The strong absorption, efficient heat conversion, high photostability, inherent low toxicity and well-defined surface chemistry of AuNPs contribute to the growing interest in their photothermal therapy (PTT) applications. The facile tunability of gold nanostructures enables engineering of AuNPs for superior near-infrared photothermal efficacy and target selectivity, which guarantee efficient and deep tissue-penetrating PTT with mitigated concerns regarding side effects by nonspecific distributions. This article discusses the current research findings with representative near-infrared-active AuNPs, which include nanoshell, nanorod, nanocage, nanostar, nanopopcorn and nanoparticle assembly systems. AuNPs successfully demonstrate potential for use in PTT, but several hurdles to clinical applications remain, including long-term toxicity and a need for sophisticated control over biodistribution and clearance. Future research directions are discussed, especially regarding the clinical translation of AuNP photosensitizers.
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Cites
Renal clearance of quantum dots
Soo Choi, H., Liu, W., Misra, P., Tanaka, E., Zimmer, J. P., Itty Ipe, B., Bawendi, M. G., & Frangioni, J. V. (2007) · Nature Biotechnology · doi:10.1038/nbt1340 · Cited by 4,476
A clearer vision for in vivo imaging
Weissleder, R. (2001) · Nature Biotechnology · doi:10.1038/86684 · Cited by 3,839
Tuning Size and Sensing Properties in Colloidal Gold Nanostars
Barbosa, S., Agrawal, A., Rodríguez-Lorenzo, L., Pastoriza-Santos, I., Alvarez-Puebla, R. A., Kornowski, A., Weller, H., & Liz-Marzán, L. M. (2010) · Langmuir · doi:10.1021/la102559e · Cited by 522
Cited by
Recent biomedical applications of gold nanoparticles: A review
Elahi, N., Kamali, M., & Baghersad, M. H. (2018) · Talanta · doi:10.1016/j.talanta.2018.02.088 · Cited by 1,174
Cancer nanomedicine for combination cancer immunotherapy
Nam, J., Son, S., Park, K. S., Zou, W., Shea, L. D., & Moon, J. J. (2019) · Nature Reviews Materials · doi:10.1038/s41578-019-0108-1 · Cited by 940
Self-citationGold Nanoparticles for Photothermal Cancer Therapy
Vines, J. B., Yoon, J.-H., Ryu, N.-E., Lim, D.-J., & Park, H. (2019) · Frontiers in Chemistry · doi:10.3389/fchem.2019.00167 · Cited by 906
Nam, J., Son, S., Ochyl, L. J., Kuai, R., Schwendeman, A., & Moon, J. J. (2018) · Nature Communications · doi:10.1038/s41467-018-03473-9 · Cited by 808
Self-citationKarimi, M., Sahandi Zangabad, P., Ghasemi, A., Amiri, M., Bahrami, M., Malekzad, H., Ghahramanzadeh Asl, H., Mahdieh, Z., Bozorgomid, M., Ghasemi, A., et al. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b00371 · Cited by 500
Metadata
- Authors
- Hwang, S., Nam, J., Jung, S., Song, J., Doh, H., & Kim, S.
- Venue
- Nanomedicine
- Publisher
- Informa UK Limited
- Published
- 2014-09
- Volume
- 9
- Issue
- 13
- Pages
- 2003-2022
- ISSN
- 1743-5889 (ISSN-L)
- 1748-6963
- OpenAlex
- W2029447122
- Cited by
- 283
- References
- 3
- FWCI
- 9.93
- Type
- journal article
- Language
- en
- Open access
- closed
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