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The cyanobacterial UV-absorbing pigment scytonemin displays radical-scavenging activity
Open accessAbstract
Scytonemin is a 544-Da hydrophobic pigment that can absorb UV-A radiation. It is present in cyanobacterial sheaths and is thought to function as a UV protectant. In this study, scytonemin was purified from the terrestrial cyanobacterium Nostoc commune, and its radical-scavenging activity was characterized. The purified scytonemin quenched an organic radical in vitro and accounted for up to 10% of the total activity of an ethanol extract of N. commune. These results suggest that the extracellular UV-absorbing pigment scytonemin has multiple roles, functioning as a UV sunscreen and an antioxidant relevant to anhydrobiosis in N. commune.
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“it is clear that MAA are multifunctional photoprotective compounds acting as chemical and biological anti-oxidants.”
From Mycosporine-Like Amino Acids for Skin Photoprotection (2019) · cites this paper as [80]
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“This has been demonstrated with different MAA from a large variety of species [78-81].”
From Mycosporine-Like Amino Acids for Skin Photoprotection (2019) · cites this paper as [80]
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Cites
Antioxidant activity applying an improved ABTS radical cation decolorization assay
Re, R., Pellegrini, N., Proteggente, A. R., Pannala, A. S., Yang, M. H., & Rice-Evans, C. A. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00315-3 · Cited by 26,986
Nitrogen mineralization: Challenges of a changing paradigm
Schimel, J. P., & Bennett, J. (2004) · Ecology · doi:10.1890/03-8002 · Cited by 2,511
THE ROLE OF VITRIFICATION IN ANHYDROBIOSIS
Crowe, J. H., Carpenter, J. F., & Crowe, L. M. (1998) · Annual Review of Physiology · doi:10.1146/annurev.physiol.60.1.73 · Cited by 1,360
CHARACTERIZATION AND BIOLOGICAL IMPLICATIONS OF SCYTONEMIN, A CYANOBACTERIAL SHEATH PIGMENT 1
García‐Pichel, F., & Castenholz, R. W. (1991) · Journal of Phycology · doi:10.1111/j.0022-3646.1991.00395.x · Cited by 733
Carotenoid radical chemistry and antioxidant/pro-oxidant properties
El-Agamey, A., Lowe, G. M., McGarvey, D. J., Mortensen, A., Phillip, D. M., Truscott, T. G., & Young, A. J. (2004) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2004.03.007 · Cited by 627
Antioxidant activity of chlorophylls and their derivatives
Lanfer‐Marquez, U. M., Barros, R. M. C., & Sinnecker, P. (2005) · Food Research International · doi:10.1016/j.foodres.2005.02.012 · Cited by 476
Cryptobiosis — a peculiar state of biological organization
Clegg, J. S. (2001) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/s1096-4959(01)00300-1 · Cited by 438
Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects
Carreto, J. I., & Carignan, M. O. (2011) · Marine Drugs · doi:10.3390/md9030387 · Cited by 396
The structure of scytonemin, an ultraviolet sunscreen pigment from the sheaths of cyanobacteria
Proteau, P. J., Gerwick, W. H., Garcia-Pichel, F., & Castenholz, R. (1993) · Experientia · doi:10.1007/bf01923559 · Cited by 392
Tamaru, Y., Takani, Y., Yoshida, T., & Sakamoto, T. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.11.7327-7333.2005 · Cited by 384
Self-citationLife and death of dried prokaryotes
Billi, D., & Potts, M. (2002) · Research in Microbiology · doi:10.1016/s0923-2508(01)01279-7 · Cited by 365
García‐Pichel, F., Sherry, N. D., & Castenholz, R. W. (1992) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1992.tb09596.x · Cited by 340
Lessons from nature: the role of sugars in anhydrobiosis
Crowe, L. M. (2002) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/s1095-6433(01)00503-7 · Cited by 329
Marine Natural Products as Novel Antioxidant Prototypes
Takamatsu, S., Hodges, T. W., Rajbhandari, I., Gerwick, W. H., Hamann, M. T., & Nagle, D. G. (2003) · Journal of Natural Products · doi:10.1021/np0204038 · Cited by 278
Cyanobacterial Responses to UV Radiation
Castenholz, R. W., & García‐Pichel, F. (2012) · Springer eBooks · doi:10.1007/978-94-007-3855-3_19 · Cited by 242
Desiccation tolerance: a simple process?
Potts, M. (2001) · Trends in Microbiology · doi:10.1016/s0966-842x(01)02231-4 · Cited by 234
Stevenson, C. S., Capper, E. A., Roshak, A., Márquez, B. L., Eichman, C., Jackson, J. R., Mattern, M. R., Gerwick, W. H., Jacobs, R. S., & Marshall, L. A. (2002) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.102.036350 · Cited by 207
Dillon, J. G., Tatsumi, C. M., Tandingan, P. G., & Castenholz, R. W. (2002) · Archives of Microbiology · doi:10.1007/s00203-001-0395-x · Cited by 177
Scherer, S., Ernst, A., Chen, T.-W., & B�ger, P. (1984) · Oecologia · doi:10.1007/bf00384277 · Cited by 176
Stevenson, C. S., Capper, E. A., Roshak, A. K., Marquez, B., Grace, K., Gerwick, W. H., Jacobs, R. S., & Marshall, L. A. (2002) · Inflammation Research · doi:10.1007/bf02684014 · Cited by 172
Helm, R. F., Huang, Z., Edwards, D., Leeson, H., Peery, W., & Potts, M. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.4.974-982.2000 · Cited by 168
Fleming, E. D., & Castenholz, R. W. (2007) · Environmental Microbiology · doi:10.1111/j.1462-2920.2007.01261.x · Cited by 161
Shirkey, B., Kovarcik, D. P., Wright, D. J., Wilmoth, G., Prickett, T., Helm, R. F., Gregory, E. M., & Potts, M. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.1.189-197.2000 · Cited by 159
Büdel, B., Karsten, U., & García‐Pichel, F. (1997) · Oecologia · doi:10.1007/s004420050296 · Cited by 148
Hill, D. R., Keenan, T. W., Helm, R. F., Potts, M., Crowe, L. M., & Crowe, J. H. (1997) · Journal of Applied Phycology · doi:10.1023/a:1007965229567 · Cited by 144
Molecular Genetics and Genomic Analysis of Scytonemin Biosynthesis in Nostoc punctiforme ATCC 29133
Soule, T. T., Stout, V., Swingley, W. D., Meeks, J. C., & García‐Pichel, F. (2007) · Journal of Bacteriology · doi:10.1128/jb.01816-06 · Cited by 142
Investigating the Initial Steps in the Biosynthesis of Cyanobacterial Sunscreen Scytonemin
Balskus, E. P., & Walsh, C. T. (2008) · Journal of the American Chemical Society · doi:10.1021/ja807192u · Cited by 137
Wright, D. J., Smith, S. C., Joardar, V., Scherer, S., Jervis, J., Warren, A., Helm, R. F., & Potts, M. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m505961200 · Cited by 130
Matsui, K., Nazifi, E., Kunita, S., Wada, N., Matsugo, S., & Sakamoto, T. (2011) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2011.07.003 · Cited by 104
Self-citationHill, D. R., Peat, A., & Potts, M. (1994) · PROTOPLASMA · doi:10.1007/bf01403474 · Cited by 104
Satoh, K., Hirai, M., Nishio, J., Yamaji, T., Kashino, Y., & Koike, H. (2002) · Plant and Cell Physiology · doi:10.1093/pcp/pcf020 · Cited by 100
Species of Nostoc Vaucher Occurring in the Sonoran Desert in Arizona
Cameron, R. E. (1962) · Transactions of the American Microscopical Society · doi:10.2307/3223790 · Cited by 100
Soule, T. T., García‐Pichel, F., & Stout, V. (2009) · Journal of Bacteriology · doi:10.1128/jb.00134-09 · Cited by 90
Sorrels, C. M., Proteau, P., & Gerwick, W. H. (2009) · Applied and Environmental Microbiology · doi:10.1128/aem.02508-08 · Cited by 89
An Enzymatic Cyclopentyl[b]indole Formation Involved in Scytonemin Biosynthesis
Balskus, E. P., & Walsh, C. T. (2009) · Journal of the American Chemical Society · doi:10.1021/ja906752u · Cited by 89
The biosynthesis of cyanobacterial sunscreen scytonemin in intertidal microbial mat communities
Balskus, E. P., Case, R. J., & Walsh, C. T. (2011) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2011.01113.x · Cited by 81
Sakamoto, T., Kumihashi, K., Kunita, S., Masaura, T., Inoue‐Sakamoto, K., & Yamaguchi, M. (2011) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2011.01114.x · Cited by 72
Self-citationMechanisms to Avoid Photoinhibition in a Desiccation-Tolerant Cyanobacterium, Nostoc commune
Fukuda, S.-Y., Yamakawa, R., Hirai, M. Y., Kashino, Y., Koike, H., & Satoh, K. (2008) · Plant and Cell Physiology · doi:10.1093/pcp/pcn018 · Cited by 72
The Successful Revival of Nostoc commune from a Herbarium Specimen Eighty- Seven Years Old
Lipman, C. B. (1941) · Bulletin of the Torrey Botanical Club · doi:10.2307/2481755 · Cited by 72
Sakamoto, T., Yoshida, T., Arima, H., Hatanaka, Y., Takani, Y., & Tamaru, Y. (2009) · Phycological Research · doi:10.1111/j.1440-1835.2008.00522.x · Cited by 70
Self-citationHirai, M., Yamakawa, R., Nishio, J., Yamaji, T., Kashino, Y., Koike, H., & Satoh, K. (2004) · Plant and Cell Physiology · doi:10.1093/pcp/pch094 · Cited by 59
Arima, H., Horiguchi, N., Takaichi, S., Kofuji, R., Ishida, K., Wada, K., & Sakamoto, T. (2011) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2011.01195.x · Cited by 55
Self-citationYoshida, T., & Sakamoto, T. (2009) · The Journal of General and Applied Microbiology · doi:10.2323/jgam.55.135 · Cited by 45
Self-citationMorsy, F. M., Kuzuha, S., Takani, Y., & Sakamoto, T. (2008) · The Journal of General and Applied Microbiology · doi:10.2323/jgam.54.243 · Cited by 44
Self-citationSquier, A. H., Airs, R. L., Hodgson, D. A., & Keely, B. J. (2004) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.1714 · Cited by 26
Research works printed but not linked: 1
- Potts, M. (2000) Nostoc. In The Ecology of Cyanobacteria, ed. by Whitton, B. A. and Potts, M., Kluwer Academic Publishers, Netherlands, pp. 465-504.
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Rastogi, R. P., & Incharoensakdi, A. (2013) · FEMS Microbiology Ecology · doi:10.1111/1574-6941.12220 · Cited by 172
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Lawrence, K. P., Long, P. F., & Young, A. R. (2019) · Current Medicinal Chemistry · doi:10.2174/0929867324666170529124237 · Cited by 157
Wada, N., Sakamoto, T., & Matsugo, S. (2013) · Metabolites · doi:10.3390/metabo3020463 · Cited by 146
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Metadata
- Authors
- Matsui, K., Nazifi, E., Hirai, Y., Wada, N., Matsugo, S., & Sakamoto, T.
- Affiliations
- Kanazawa University (JP)
- Venue
- The Journal of General and Applied Microbiology
- Publisher
- Microbiology Research Foundation
- Published
- 2012
- Volume
- 58
- Issue
- 2
- Pages
- 137-144
- ISSN
- 0022-1260 (ISSN-L)
- 1349-8037
- OpenAlex
- W2162164905
- Cited by
- 133
- References
- 45
- Citations by year
- 2026: 6 · 2025: 9 · 2024: 2 · 2023: 8 · 2022: 22 · 2021: 10 · 2020: 31 · 2019: 6 · 2018: 7 · 2017: 12 · 2016: 7 · 2015: 3 · 2014: 4 · 2013: 6
- FWCI
- 3.69
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Journal of General and Applied Microbiology (publishedVersion)
- PubMed (publishedVersion)
- Institutional Repositories DataBase (IRDB) (submittedVersion)
- Kanazawa University Repository for Academic Resources (DSpace) (Kanazawa University) (submittedVersion, cc-by-nc-nd)
- Funders
- Japan Society for the Promotion of Science (22510227)
- National Institute for Basic Biology
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Microbial Metabolism and Applications
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Biocrusts and Microbial Ecology
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Keywords
- scytonemin, free radical scavenging, antioxidant activity, UV protection, Nostoc commune, extracellular pigments, anhydrobiosis, UVA absorption, pigment purification
- MeSH terms
- Absorption, Cyanobacteria, Indoles, Phenols, Pigments, Biological, Sunscreening Agents, Ultraviolet Rays, Free Radical Scavengers, Nostoc commune
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