Beneficial effects of Control-IQ automated insulin delivery in basal-bolus and basal-only insulin users with type 2 diabetes
Open accessAbstract
The t:slim X2 insulin pump with Control-IQ technology (Control-IQ) advanced hybrid closed-loop automated insulin delivery system was evaluated in this prospective single-arm trial. Thirty adults with type 2 diabetes using the Control-IQ system showed substantial glycemic improvement with no increase in hypoglycemia. Mean time in range (70–180 mg/dL) improved 15%, representing an increase of 3.6 hours/day, and mean glucose decreased by 22 mg/dL.
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A small single-arm prospective study in adults with type 2 diabetes on MDI who started AID showed TIR improvement of 15% at 6 weeks.
“Nevertheless, data are increasing; a small, single-arm prospective study in adults with type 2 diabetes who were on MDI and started an AID system revealed improvement of TIR by 15% at 6 weeks (248).”
From 7. Diabetes Technology: Standards of Care in Diabetes—2025 (2025) · cites this paper as [248]
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7. Diabetes Technology: Standards of Care in Diabetes—2025
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- Authors
- Levy, C. J., Raghinaru, D., Kudva, Y. C., Pandit, K., Blevins, T., Casaubon, L., Desjardins, D., Levister, C. M., O’Malley, G., Reid, C., Lum, J., Kollman, C., & Beck, R. W.
- Affiliations
- Icahn School of Medicine at Mount Sinai (US)
- Jaeb Center for Health Research (US)
- Mayo Clinic (US)
- Texas Diabetes & Endocrinology (US)
- Corresponding author
- Lum, John
- ORCID
- Venue
- Clinical Diabetes
- Publisher
- American Diabetes Association
- Published
- 2023-08-28
- Volume
- 42
- Issue
- 1
- Pages
- 116-124
- ISSN
- 0891-8929 (ISSN-L)
- 1945-4953
- PMC
- PMC10788662
- OpenAlex
- W4386212186
- Cited by
- 37
- References
- 18
- Citations by year
- 2026: 5 · 2025: 18 · 2024: 13 · 2023: 1
- FWCI
- 7.54
- Type
- journal article
- Language
- en
- Open access
- green
- pmc.ncbi.nlm.nih.gov
- Locations
- Clinical Diabetes (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Tandem Diabetes Care, Inc
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Keywords
- type 2 diabetes, artificial pancreas, Control-IQ, hybrid closed-loop system, multiple daily insulin injections, glycemic control, time in range, hypoglycemia, continuous glucose monitoring
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