Unique Arrangement of α- and β-Cells in Human Islets of Langerhans

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Items 101–200 of 316

1. Passively Operated Microfluidic Device for Stimulation and Secretion Sampling of Single Pancreatic Islets
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2. Insulin, glucagon and somatostatin stores in the pancreas of subjects with type-2 diabetes and their lean and obese non-diabetic controls
   Henquin, Jean-Claude, Ibrahim, Majeed M., Rahier, Jacques · 2017 · Scientific Reports
3. Natural products targeting inflammation-related metabolic disorders: A comprehensive review
   Firzan Nainu, Andri Frediansyah, Sukamto Salang Mamada, Andi Dian Permana, Mirnawati Salampe, Deepak Chandran, Talha Bin Emran, Jesús Simal‐Gándara · 2023 · Heliyon
4. Paracrine and autocrine control of insulin secretion in human islets: evidence and pending questions
   Jean‐Claude Henquin · 2020 · American Journal of Physiology-Endocrinology and Metabolism
5. Islet–immune interactions in type 1 diabetes: the nexus of beta cell destruction
   Leeana D. Peters, Amanda L. Posgai, Todd M. Brusko · 2019 · Clinical & Experimental Immunology
6. Advancing Animal Models of Human Type 1 Diabetes by Engraftment of Functional Human Tissues in Immunodeficient Mice
   Michael A. Brehm, Alvin C. Powers, Leonard D. Shultz, Dale L. Greiner · 2012 · Cold Spring Harbor Perspectives in Medicine
7. The vascular architecture of the pancreatic islets: A homage to august Krogh.
   M. Muratore, Cristiano Santos, P. Rorsman · 2020 · Comparative biochemistry and physiology. Part A, Molecular & integrative physiology
8. Conformal coating by multilayer nano-encapsulation for the protection of human pancreatic islets: In-vitro and in-vivo studies
   Farooq Syed, Marco Bugliani, Michela Novelli, Francesco Olimpico, Mara Suleiman, Lorella Marselli, Ugo Boggi, Franco Filipponi, Vittoria Raffa, Silke Krol et al. · 2018 · Nanomedicine Nanotechnology Biology and Medicine
9. Microfluidic perfusion systems for secretion fingerprint analysis of pancreatic islets: applications, challenges and opportunities
   F. Rafael Castiello, Khalil Heileman, Maryam Tabrizian · 2015 · Lab on a Chip
10. The forgotten members of the glucagon family.
    D. Bataille, S. Dalle · 2014 · Diabetes Research and Clinical Practice
11. Mitochondrial Dynamics and Insulin Secretion
    Uma Dhiraj Kabra, Martin Jastroch · 2023 · International Journal of Molecular Sciences
12. Determinants and dynamics of pancreatic islet architecture
    Melissa T. Adams, Barak Blum · 2022 · Islets
13. From Genetic Association to Molecular Mechanisms for Islet-cell Dysfunction in Type 2 Diabetes
    Katia K. Mattis, Anna L. Gloyn · 2020 · Journal of Molecular Biology
14. Antagonistic Glucagon Receptor Antibody Promotes α-Cell Proliferation and Increases β-Cell Mass in Diabetic Mice
    R. Wei, Liangbiao Gu, J. Yang, Kun Yang, Junling Liu, Yun-Yi Le, Shan Lang, Hai-Ning Wang, Dung Thai, Hai Yan et al. · 2019 · iScience
15. Co-expression of the homologous proteases fibroblast activation protein and dipeptidyl peptidase-IV in the adult human Langerhans islets
    Petr Bušek, Petr Hrabal, Premysl Fric, Aleksi Šedo · 2014 · Histochemistry and Cell Biology
16. Islet Microvasculature Alterations With Loss of Beta-cells in Patients With Type 1 Diabetes
    Joseph S. Canzano, Lith Nasif, E. Butterworth, Dong-Tao A. Fu, M. Atkinson, M. Campbell-Thompson · 2018 · Journal of Histochemistry and Cytochemistry
17. The challenge of correctly reporting hormones content and secretion in isolated human islets
    Jean‐Claude Henquin · 2019 · Molecular Metabolism
18. An engineered macroencapsulation membrane releasing FTY720 to precondition pancreatic islet transplantation
    Daniel T. Bowers, Claire E. Olingy, P. Chhabra, L. Langman, Parker H Merrill, Ritu S Linhart, Michael L. Tanes, Dan Lin, K. Brayman, E. Botchwey · 2017 · Journal of Biomedical Materials Research. Part B - Applied biomaterials
19. Ca2+ oscillations, waves, and networks in islets from human donors with and without type 2 diabetes
    M. Gosak, Richard Yan-Do, Hao-Peng Lin, P. Macdonald, A. Stožer · 2021 · bioRxiv
20. Pancreatic Pseudoislets: An Organoid Archetype for Metabolism Research
    Mollie S. H. Friedlander, Vy Nguyen, Seung K. Kim, Romina J. Bevacqua · 2021 · Diabetes
21. Lineage Reprogramming: A Promising Road for Pancreatic β Cell Regeneration
    Rui Wei, Tianpei Hong · 2016 · Trends in Endocrinology and Metabolism
22. Mathematical models of pancreatic islet size distributions
    Junghyo Jo, Manami Hara, Ulf Ahlgren, Robert L. Sorenson, Vipul Periwal · 2012 · Islets
23. Dipeptidyl peptidase-4 (DPP-4): Localization and activity in human and rodent islets.
    Lie-Hua Liu, B. Omar, P. Marchetti, Ah-Ren Bo · 2014 · Biochemical and Biophysical Research Communications - BBRC
24. The Sympathetic‐Immune Milieu in Metabolic Health and Diseases: Insights from Pancreas, Liver, Intestine, and Adipose Tissues
    Wenran Ren, Meng Hua, Fang Cao, Wenwen Zeng · 2023 · Advanced Science
25. Evidence for the existence and potential roles of intra-islet glucagon-like peptide-1
    Scott A. Campbell, Janyne Johnson, Peter E. Light · 2021 · Islets
26. Pancreatic islet response to diabetes during pregnancy in rats
    Franciane Quintanilha Gallego, Yuri Karen Sinzato, Carolina Abreu Miranda, Isabela Lovizutto Iessi, Bruna Dallaqua, Gustavo Tadeu Volpato, Wellerson Rodrigo Scarano, Sebastián San Martín, Débora Cristina Damasceno · 2018 · Life Sciences
27. Tissue engineering and 3D printing of bioartificial pancreas for regenerative medicine in diabetes
    Andreas Alvin Purnomo Soetedjo, Jia Min Lee, Hwee Hui Lau, Guo Liang Goh, Jia An, Yexin Koh, Wai Yee Yeong, Adrian Kee Keong Teo · 2021 · Trends in Endocrinology and Metabolism
28. Cell Autonomous Dysfunction and Insulin Resistance in Pancreatic α Cells
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29. Design Principles of Pancreatic Islets: Glucose-Dependent Coordination of Hormone Pulses
    Danh-Tai Hoang, Manami Hara, Junghyo Jo · 2016 · PLoS ONE
30. From Isles of Königsberg to Islets of Langerhans: Examining the Function of the Endocrine Pancreas Through Network Science
    Andraž Stožer, Marko Šterk, Eva Paradiž Leitgeb, Rene Markovič, Maša Skelin Klemen, Cara E. Ellis, Lidija Križančić Bombek, Jurij Dolenšek, Patrick E. MacDonald, Marko Gosak · 2022 · Frontiers in Endocrinology
31. Metabolic and Functional Heterogeneity in Pancreatic β Cells
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32. The Role of the α Cell in the Pathogenesis of Diabetes: A World beyond the Mirror
    María Sofía Martínez, Alexander Manzano, Luis Carlos Olivar, Manuel Nava, Juan José Salazar, Luis D’Marco, Rina Ortíz, Maricarmen Chacín, Marion Guerrero‐Wyss, Mayela Cabrera de Bravo et al. · 2021 · International Journal of Molecular Sciences
33. Intercellular Communication in the Islet of Langerhans in Health and Disease
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34. Membrane Potential and Calcium Dynamics in Beta Cells from Mouse Pancreas Tissue Slices: Theory, Experimentation, and Analysis
    Jurij Dolenšek, Denis Špelič, Maša Skelin Klemen, Borut Žalik, Marko Gosak, Marjan Slak Rupnik, Andraž Stožer · 2015 · Sensors
35. The Beta Cell in Its Cluster: Stochastic Graphs of Beta Cell Connectivity in the Islets of Langerhans
    Deborah A. Striegel, Manami Hara, Vipul Periwal · 2015 · PLoS Computational Biology
36. Endothelium-derived essential signals involved in pancreas organogenesis
    Dodanim Talavera‐Adame · 2015 · World Journal of Experimental Medicine
37. Ontogeny of Neuro-Insular Complexes and Islets Innervation in the Human Pancreas
    A. Proshchina, Yulia S. Krivova, V. Barabanov, S. Saveliev · 2014 · Frontiers in Endocrinology
38. Intra-islet glucagon secretion and action in the regulation of glucose homeostasis
    Qinghua Wang, Xinyun Liang, Susanne Wang · 2013 · Frontiers in Physiology
39. Human pluripotent stem cell based islet models for diabetes research.
    D. Balboa, T. Otonkoski · 2015 · Best practice & research. Clinical endocrinology & metabolism
40. Regulated and adaptive in vivo insulin secretion from islets only containing β-cells
    Marta Perez-Frances, Eva Bru-Tarí, Christian M. Cohrs, Maria Valentina Abate, Léon van Gurp, Kenichiro Furuyama, Stephan Speier, Fabrizio Thorel, Pedro Luis Herrera · 2024 · Nature Metabolism
41. Bioengineering the Vascularized Endocrine Pancreas: A Fine-Tuned Interplay Between Vascularization, Extracellular-Matrix-Based Scaffold Architecture, and Insulin-Producing Cells
    Cataldo Pignatelli, Francesco Campo, Alessia Neroni, Lorenzo Piemonti, Antonio Citro · 2022 · Transplant International
42. Reduced synchroneity of intra-islet Ca2+ oscillations in vivo in Robo-deficient β cells
    Melissa T. Adams, JaeAnn M. Dwulet, Jennifer K. Briggs, Christopher A. Reissaus, Erli Jin, Joseph M. Szulczewski, Melissa R. Lyman, Sophia M. Sdao, Vira V. Kravets, Sutichot D. Nimkulrat et al. · 2021 · eLife
43. Inappropriate glucagon and GLP-1 secretion in individuals with long-standing type 1 diabetes: effects of residual C-peptide
    Charles H. Thivolet, Lucien Marchand, Karim Chikh · 2019 · Diabetologia
44. Comparison of pancreatic beta cells and alpha cells under hyperglycemia: Inverse coupling in pAkt-FoxO1
    Mi-Kyung Kim, Hyun Mi Shin, Hye-Sook Jung, Eun Ju Lee, Tae Kyoon Kim, Tae Nyun Kim, Min Jeong Kwon, Soon Hee Lee, Byoung Doo Rhee, Jeong Hyun Park · 2017 · Diabetes Research and Clinical Practice
45. Diabetes imaging—quantitative assessment of islets of Langerhans distribution in murine pancreas using extended-focus optical coherence microscopy
    Corinne Berclaz, Joan Goulley, Martin Villiger, Christophe Pache, Arno Bouwens, Erica Martin-Williams, Dimitri Van De Ville, Anthony C. Davison, Anne Grapin‐Botton, Theo Lasser · 2012 · Biomedical Optics Express
46. The Ontogeny of the Endocrine Pancreas in the Fetal/Newborn Baboon
    Amy R. Quinn, C. Blanco, C. Perego, G. Finzi, S. La Rosa, C. Capella, Rodolfo Guardado-Mendoza, Francesca Casiraghi, A. Gastaldelli, Marney C. Johnson et al. · 2012 · Journal of Endocrinology
47. Single nucleus RNA sequencing maps acinar cell states in a human pancreas cell atlas
    L. Tosti, Y. Hang, O. Debnath, Sebastian Tiesmeyer, Timo Trefzer, K. Steiger, F. W. Ten, Soeren Lukassen, S. Ballke, A. Kühl et al. · 2019 · bioRxiv
48. Histology of Type 1 Diabetes Pancreas.
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49. Development of a peptide-functionalized imaging nanoprobe for the targeting of (FXYD2)γa as a highly specific biomarker of pancreatic beta cells.
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50. Expression and Function of Monoacylglycerol Lipase in Mouse β-cells and Human Islets of Langerhans
    Chen Li, A. Vilches-Flores, Min Zhao, S. Amiel, Peter M. Jones, S. Persaud · 2012 · Cellular Physiology and Biochemistry
51. Cell-to-cell contact dependence and junctional protein content are correlated with in vivo maturation of pancreatic beta cells.
    J. Santos-Silva, Carolina Prado de França Carvalho, Ricardo Beltrame de Oliveira, A. Boschero, C. Collares-Buzato · 2012 · Canadian Journal of Physiology and Pharmacology
52. The Foundation for Engineering a Pancreatic Islet Niche
    Smit N. Patel, C. Mathews, R. Chandler, C. Stabler · 2022 · Frontiers in Endocrinology
53. Role of the active zone protein, ELKS, in insulin secretion from pancreatic β-cells
    Mica Ohara‐Imaizumi, Kyota Aoyagi, Toshihisa Ohtsuka · 2019 · Molecular Metabolism
54. Pancreatic β-cell heterogeneity in adult human islets and stem cell-derived islets
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55. Restoring normal islet mass and function in type 1 diabetes through regenerative medicine and tissue engineering
    Nicole A. J. Krentz, Lonnie D. Shea, Mark O. Huising, James Shaw · 2021 · The Lancet Diabetes & Endocrinology
56. Antidiabetic drug therapy alleviates type 1 diabetes in mice by promoting pancreatic α-cell transdifferentiation
    D. Sarnobat, Charlotte R Moffett, N. Tanday, F. Reimann, F. Gribble, P. Flatt, A. Tarasov · 2020 · bioRxiv
57. Pancreatic Mesenchyme Regulates Islet Cellular Composition in a Patched/Hedgehog-Dependent Manner
    Daniel Hibsher, Alona Epshtein, Nufar Oren, Limor Landsman · 2016 · Scientific Reports
58. Biophysical modeling of β-cells networks: Realistic architectures and heterogeneity effects.
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59. Controlled 3D co-culture of beta cells and endothelial cells in a micropatterned collagen sheet for reproducible construction of an improved pancreatic pseudo-tissue
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60. Exploring the molecular mechanisms underlying α- and β-cell dysfunction in diabetes
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61. Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication
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62. Conflicting Views About Interactions Between Pancreatic α-Cells and β-Cells
    Gordon C. Weir, Susan Bonner‐Weir · 2023 · Diabetes
63. The functional importance of the cellular and extracellular composition of the islets of Langerhans
    Fredrik C. Wieland, Clemens van Blitterswijk, Aart A. van Apeldoorn, Vanessa L.S. LaPointe · 2021 · Journal of Immunology and Regenerative Medicine
64. Facilitating islet transplantation using a three-step approach with mesenchymal stem cells, encapsulation, and pulsed focused ultrasound
    Mehdi Razavi, Tanchen Ren, Fengyang Zheng, Arsenii V. Telichko, Jing Wang, Jeremy Dahl, Utkan Demirci, Avnesh Sinh Thakor · 2020 · Stem Cell Research & Therapy
65. Engineered Biomaterials for Enhanced Function of Insulin‐Secreting β‐Cell Organoids
    Michael D. Hunckler, Andrés J. García · 2020 · Advanced Functional Materials
66. Structure of Islets and Vascular Relationship to the Exocrine Pancreas
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67. 3D-Models of Insulin-Producing β-Cells: from Primary Islet Cells to Stem Cell-Derived Islets
    Diana Ribeiro, A. Kvist, P. Wittung-Stafshede, R. Hicks, A. Forslöw · 2017 · Stem Cell Reviews and Reports
68. Engineering of microscale three-dimensional pancreatic islet modelsin vitroand their biomedical applications
    Bin Gao, Lin Wang, Shuang Han, Belinda Pingguan‐Murphy, Xiaohui Zhang, Feng Xu · 2015 · Critical Reviews in Biotechnology
69. Engraftment Versus Immunosuppression
    Simona Marzorati, Raffaella Melzi, Antonio Citro, Elisa Cantarelli, Alessia Mercalli, Marina Scavini, Lorenzo Piemonti · 2014 · Transplantation
70. Whole‐Mount Imaging Demonstrates Hypervascularity of the Pancreatic Ducts and Other Pancreatic Structures
    Y. El-Gohary, S. Tulachan, M. Branca, S. Sims-Lucas, Ping Guo, K. Prasadan, C. Shiota, G. Gittes · 2012 · The Anatomical Record
71. Glucagon Responses of Isolated a Cells to Glucose, Insulin, Somatostatin, and Leptin
    Lijun Chen, Jacques Philippé, Roger H. Unger · 2011 · Endocrine Practice
72. The Importance of Intra-Islet Communication in the Function and Plasticity of the Islets of Langerhans during Health and Diabetes
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73. Challenges and opportunities in the islet transplantation microenvironment: a comprehensive summary of inflammatory cytokine, immune cells, and vascular endothelial cells
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74. Pancreatic Alpha Cell Mass Across Adult Human Lifespan
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75. Modeling Spatial Correlation of Transcripts with Application to Developing Pancreas
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76. Very Short-Term Effects of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin on the Secretion of Insulin, Glucagon, and Incretin Hormones in Japanese Patients with Type 2 Diabetes Mellitus: Analysis of Meal Tolerance Test Data
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77. Topographical Arrangement of α- and β-Cells Within Neo-islet Tissues Engineered by Islet Cell Sheet Transplantation in Mice
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78. β-Cell Generation: Can Rodent Studies Be Translated to Humans?
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79. Comprehensive analysis of human tissues reveals unique expression and localization patterns of HSF1 and HSF2
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80. Decellularization of Human Pancreatic Fragments with Pronounced Signs of Structural Changes
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81. Enhanced spatial resolution in magnetic resonance imaging by dynamic nuclear polarization at 5 K
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82. Activation of GPR119 Stimulates Humanβ-Cell Replication and Neogenesis in Humanized Mice with Functional Human Islets
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83. Sixty Years of Drug Discovery for Type 2 Diabetes: Where Are We Now?
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84. Pancreatic endocrine cell arrangement during human ontogeny
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85. Insulin regulates glucagon-like peptide-1 secretion by pancreatic alpha cells
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86. Islet Amyloid in Whole Pancreas Transplants for Type 1 Diabetes Mellitus (DM): Possible Role of Type 2 DM for Graft Failure
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87. Activated protein C and its potential applications in prevention of islet β-cell damage and diabetes.
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88. A computational systems analysis of factors regulating α cell glucagon secretion
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89. Three-dimensional bioprinting of functional β-islet-like constructs
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90. Time zones of pancreatic islet metabolism
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91. Long in the shade, glucagon re‐occupies centre court
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92. Sex-dependent intra-islet structural rearrangements affecting alpha-to-beta cell interactions lead to adaptive enhancements of Ca2+ dynamics in prediabetic beta cells
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93. Cell Heterogeneity and Paracrine Interactions in Human Islet Function: A Perspective Focused in β-Cell Regeneration Strategies
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94. Asymmetrical distribution of δ and PP cells in human pancreatic islets.
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95. Histomorphological Developmental Study of Advanced Postnatal of the Pancreas of Local Rabbit
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96. Islet Number Rather Than Islet Size Is a Major Determinant of β- and α-Cell Mass in Humans
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97. Physiology of pancreatic β-cells: Ion channels and molecular mechanisms implicated in stimulus-secretion coupling
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98. Sex differences in androgen regulation of metabolism in nonhuman primates
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99. Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
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100. Dynamic changes in insulin and glucagon during disease progression in rhesus monkeys with obesity‐related type 2 diabetes mellitus
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