Unique Arrangement of α- and β-Cells in Human Islets of Langerhans

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Items 101–200 of 316

1. Passively Operated Microfluidic Device for Stimulation and Secretion Sampling of Single Pancreatic Islets
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2. Insulin, glucagon and somatostatin stores in the pancreas of subjects with type-2 diabetes and their lean and obese non-diabetic controls
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3. Natural products targeting inflammation-related metabolic disorders: A comprehensive review
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4. Paracrine and autocrine control of insulin secretion in human islets: evidence and pending questions.
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5. Islet–immune interactions in type 1 diabetes: the nexus of beta cell destruction
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6. Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice.
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7. The vascular architecture of the pancreatic islets: A homage to august Krogh.
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8. Conformal coating by multilayer nano-encapsulation for the protection of human pancreatic islets: In-vitro and in-vivo studies.
   Farooq Syed, M. Bugliani, M. Novelli, F. Olimpico, M. Suleiman, L. Marselli, U. Boggi, F. Filipponi, V. Raffa, S. Krol et al. · 2018 · Nanomedicine: Nanotechnology, Biology and Medicine
9. Microfluidic perfusion systems for secretion fingerprint analysis of pancreatic islets: applications, challenges and opportunities.
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10. The forgotten members of the glucagon family.
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11. Mitochondrial Dynamics and Insulin Secretion
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12. Determinants and dynamics of pancreatic islet architecture
    Melissa T. Adams, Barak Blum · 2022 · Islets
13. From Genetic Association to Molecular Mechanisms for Islet-cell Dysfunction in Type 2 Diabetes
    Katia K. Mattis, Anna L. Gloyn · 2020 · Journal of Molecular Biology
14. Antagonistic Glucagon Receptor Antibody Promotes α-Cell Proliferation and Increases β-Cell Mass in Diabetic Mice
    R. Wei, Liangbiao Gu, J. Yang, Kun Yang, Junling Liu, Yun-Yi Le, Shan Lang, Hai-Ning Wang, Dung Thai, Hai Yan et al. · 2019 · iScience
15. Co-expression of the homologous proteases fibroblast activation protein and dipeptidyl peptidase-IV in the adult human Langerhans islets
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16. Islet Microvasculature Alterations With Loss of Beta-cells in Patients With Type 1 Diabetes
    Joseph S. Canzano, Lith Nasif, E. Butterworth, Dong-Tao A. Fu, M. Atkinson, M. Campbell-Thompson · 2018 · Journal of Histochemistry and Cytochemistry
17. The challenge of correctly reporting hormones content and secretion in isolated human islets
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18. An engineered macroencapsulation membrane releasing FTY720 to precondition pancreatic islet transplantation
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19. Ca2+ oscillations, waves, and networks in islets from human donors with and without type 2 diabetes
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20. Pancreatic Pseudoislets: An Organoid Archetype for Metabolism Research
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21. Lineage Reprogramming: A Promising Road for Pancreatic β Cell Regeneration.
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22. Mathematical models of pancreatic islet size distributions
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23. Dipeptidyl peptidase-4 (DPP-4): Localization and activity in human and rodent islets.
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24. The Sympathetic‐Immune Milieu in Metabolic Health and Diseases: Insights from Pancreas, Liver, Intestine, and Adipose Tissues
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25. Evidence for the existence and potential roles of intra-islet glucagon-like peptide-1
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26. Pancreatic islet response to diabetes during pregnancy in rats
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27. Tissue engineering and 3D printing of bioartificial pancreas for regenerative medicine in diabetes.
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28. Cell Autonomous Dysfunction and Insulin Resistance in Pancreatic α Cells
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29. Design Principles of Pancreatic Islets: Glucose-Dependent Coordination of Hormone Pulses
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30. From Isles of Königsberg to Islets of Langerhans: Examining the Function of the Endocrine Pancreas Through Network Science
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31. Metabolic and functional heterogeneity in pancreatic β cells.
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32. The Role of the α Cell in the Pathogenesis of Diabetes: A World beyond the Mirror
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33. Intercellular Communication in the Islet of Langerhans in Health and Disease
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34. Membrane Potential and Calcium Dynamics in Beta Cells from Mouse Pancreas Tissue Slices: Theory, Experimentation, and Analysis
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35. The Beta Cell in Its Cluster: Stochastic Graphs of Beta Cell Connectivity in the Islets of Langerhans
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36. Endothelium-derived essential signals involved in pancreas organogenesis.
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37. Ontogeny of Neuro-Insular Complexes and Islets Innervation in the Human Pancreas
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38. Intra-islet glucagon secretion and action in the regulation of glucose homeostasis
    Qinghua Wang, Xinyun Liang, Susanne Wang · 2013 · Frontiers in Physiology
39. Human pluripotent stem cell based islet models for diabetes research.
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40. Regulated and adaptive in vivo insulin secretion from islets only containing β-cells
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41. Bioengineering the Vascularized Endocrine Pancreas: A Fine-Tuned Interplay Between Vascularization, Extracellular-Matrix-Based Scaffold Architecture, and Insulin-Producing Cells
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42. Reduced synchroneity of intra-islet Ca2+ oscillations in vivo in Robo-deficient β cells
    Melissa T Adams, JaeAnn M. Dwulet, J. Briggs, Christopher A. Reissaus, Er-Li Jin, Joseph M. Szulczewski, Melissa R. Lyman, Sophia M. Sdao, Vira Kravets, Sutichot D Nimkulrat et al. · 2021 · eLife
43. Inappropriate glucagon and GLP-1 secretion in individuals with long-standing type 1 diabetes: effects of residual C-peptide
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44. Comparison of pancreatic beta cells and alpha cells under hyperglycemia: Inverse coupling in pAkt-FoxO1
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45. Diabetes imaging—quantitative assessment of islets of Langerhans distribution in murine pancreas using extended-focus optical coherence microscopy
    C. Berclaz, J. Goulley, M. Villiger, C. Pache, A. Bouwens, E. Martin-Williams, D. van de Ville, A. Davison, A. Grapin-Botton, T. Lasser · 2012 · Biomedical Optics Express
46. The Ontogeny of the Endocrine Pancreas in the Fetal/Newborn Baboon
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47. Single nucleus RNA sequencing maps acinar cell states in a human pancreas cell atlas
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48. Histology of Type 1 Diabetes Pancreas.
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49. Development of a peptide-functionalized imaging nanoprobe for the targeting of (FXYD2)γa as a highly specific biomarker of pancreatic beta cells.
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50. Expression and Function of Monoacylglycerol Lipase in Mouse β-cells and Human Islets of Langerhans
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51. Cell-to-cell contact dependence and junctional protein content are correlated with in vivo maturation of pancreatic beta cells.
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52. The Foundation for Engineering a Pancreatic Islet Niche
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53. Role of the active zone protein, ELKS, in insulin secretion from pancreatic β-cells
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54. Pancreatic β-cell heterogeneity in adult human islets and stem cell-derived islets
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55. Restoring normal islet mass and function in type 1 diabetes through regenerative medicine and tissue engineering
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56. Antidiabetic drug therapy alleviates type 1 diabetes in mice by promoting pancreatic α-cell transdifferentiation
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57. Pancreatic Mesenchyme Regulates Islet Cellular Composition in a Patched/Hedgehog-Dependent Manner
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58. Biophysical modeling of β-cells networks: Realistic architectures and heterogeneity effects.
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59. Controlled 3D co-culture of beta cells and endothelial cells in a micropatterned collagen sheet for reproducible construction of an improved pancreatic pseudo-tissue
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60. Exploring the molecular mechanisms underlying α- and β-cell dysfunction in diabetes
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61. Localized GLP-1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication
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62. Conflicting Views About Interactions Between Pancreatic α-Cells and β-Cells
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63. The functional importance of the cellular and extracellular composition of the islets of Langerhans
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64. Facilitating islet transplantation using a three-step approach with mesenchymal stem cells, encapsulation, and pulsed focused ultrasound
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65. Engineered Biomaterials for Enhanced Function of Insulin‐Secreting β‐Cell Organoids
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66. Structure of Islets and Vascular Relationship to the Exocrine Pancreas
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67. 3D-Models of Insulin-Producing β-Cells: from Primary Islet Cells to Stem Cell-Derived Islets
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68. Engineering of microscale three-dimensional pancreatic islet models in vitro and their biomedical applications
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69. Engraftment Versus Immunosuppression: Cost-Benefit Analysis of Immunosuppression After Intrahepatic Murine Islet Transplantation
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70. Whole‐Mount Imaging Demonstrates Hypervascularity of the Pancreatic Ducts and Other Pancreatic Structures
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71. Glucagon responses of isolated α cells to glucose, insulin, somatostatin, and leptin.
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72. The Importance of Intra-Islet Communication in the Function and Plasticity of the Islets of Langerhans during Health and Diabetes
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73. Challenges and opportunities in the islet transplantation microenvironment: a comprehensive summary of inflammatory cytokine, immune cells, and vascular endothelial cells
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74. Pancreatic Alpha Cell Mass Across Adult Human Lifespan
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75. Modeling Spatial Correlation of Transcripts with Application to Developing Pancreas
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76. Very Short-Term Effects of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin on the Secretion of Insulin, Glucagon, and Incretin Hormones in Japanese Patients with Type 2 Diabetes Mellitus: Analysis of Meal Tolerance Test Data
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77. Topographical arrangement of α- and β-cells within neo-islet tissues engineered by islet cell sheet transplantation in mice.
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78. β-Cell Generation: Can Rodent Studies Be Translated to Humans?
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79. Comprehensive analysis of human tissues reveals unique expression and localization patterns of HSF1 and HSF2
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80. Decellularization of Human Pancreatic Fragments with Pronounced Signs of Structural Changes
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81. Enhanced spatial resolution in magnetic resonance imaging by dynamic nuclear polarization at 5 K
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82. Activation of GPR119 Stimulates Humanβ-Cell Replication and Neogenesis in Humanized Mice with Functional Human Islets
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83. Sixty Years of Drug Discovery for Type 2 Diabetes: Where Are We Now?
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84. Pancreatic endocrine cell arrangement during human ontogeny.
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85. Insulin regulates glucagon-like peptide-1 secretion by pancreatic alpha cells
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86. Islet Amyloid in Whole Pancreas Transplants for Type 1 Diabetes Mellitus (DM): Possible Role of Type 2 DM for Graft Failure
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87. Activated protein C and its potential applications in prevention of islet β-cell damage and diabetes.
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88. A computational systems analysis of factors regulating α cell glucagon secretion
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89. Three-dimensional bioprinting of functional β-islet-like constructs
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90. Time zones of pancreatic islet metabolism
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91. Long in the shade, glucagon re‐occupies centre court
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92. Sex-dependent intra-islet structural rearrangements affecting alpha-to-beta cell interactions lead to adaptive enhancements of Ca2+ dynamics in prediabetic beta cells
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93. Cell Heterogeneity and Paracrine Interactions in Human Islet Function: A Perspective Focused in β-Cell Regeneration Strategies
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94. Asymmetrical distribution of δ and PP cells in human pancreatic islets.
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95. Histomorphological Developmental Study of Advanced Postnatal of the Pancreas of Local Rabbit
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96. Islet number rather than islet size is a major determinant of β- and α-cell mass in humans.
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97. Physiology of pancreatic β-cells: Ion channels and molecular mechanisms implicated in stimulus-secretion coupling.
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98. Sex differences in androgen regulation of metabolism in nonhuman primates
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99. Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
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100. Dynamic changes in insulin and glucagon during disease progression in rhesus monkeys with obesity‐related type 2 diabetes mellitus
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