Physical Activity and Diabetes Complications in Patients With Type 1 Diabetes
Abstract
Physical activity exerts numerous beneficial health effects, and the evidence favoring a physically active lifestyle in the treatment of chronic diseases is substantial (1). For patients with diabetes, physical activity is considered important (2). In theory, regular physical activity may prevent diabetes complications through beneficial effects on glycemic control, insulin sensitivity, blood pressure, lipid profile, and endothelial function. However, physical activity could also cause adverse effects or patients may not be able to exercise due to complications. Little, however, is known about the relationship between physical activity and diabetes complications (3). Therefore, we investigated the associations between physical activity and microvascular and macrovascular diabetic complications in a large cohort of patients with type 1 diabetes from the Finnish Diabetic Nephropathy (FinnDiane) Study. The FinnDiane Study and the assessment of self-reported leisure-time physical activity (LTPA) by a questionnaire have previously been described (4). This is a cross-sectional analysis of 1,945 patients with data on LTPA. Renal status was based on at least three urine collections. Renal function was evaluated by the Cockcroft-Gault formula (5) for estimated creatinine clearance. Data on retinopathy and cardiovascular disease (CVD) were obtained from medical records. Differences between groups were …
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Regular physical activity is associated with reduced risk of microvascular complications, osteoporosis, and cancer in people with type 1 diabetes.
“In addition, regular physical activity is associated with reduced risk of microvascular complications, osteoporosis, and cancer in people with type 1 diabetes (148).”
Cites
Association of depression and diabetes complications: a meta-analysis
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Kahn, J. K., Zola, B., Juni, J. E., & Vinik, A. I. (1986) · Diabetes Care · doi:10.2337/diacare.9.4.389 · Cited by 102 · see citing works
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Holt, R. I. G., DeVries, J. H., Hess-Fischl, A., Hirsch, I. B., Kirkman, M. S., Klupa, T., Ludwig, B., Nørgaard, K., Pettus, J., Renard, E., et al. (2021) · Diabetes Care · doi:10.2337/dci21-0043 · Cited by 699 · see citing works
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Wu, N., Bredin, S. S. D., Guan, Y., Dickinson, K., Kim, D. D., Chua, Z., Kaufman, K., & Warburton, D. E. R. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8020253 · Cited by 110 · see citing works
the FinnDiane Study Group, Tikkanen-Dolenc, H., Wadén, J., Forsblom, C., Harjutsalo, V., Thorn, L. M., Saraheimo, M., Elonen, N., Hietala, K., Summanen, P., et al. (2020) · Acta Diabetologica · doi:10.1007/s00592-019-01454-y · Cited by 43 · see citing works
Self-citation
- Authors
- Wadén, J., Forsblom, C., Thorn, L. M., Saraheimo, M., Rosengård-Bärlund, M., Heikkilä, O., Lakka, T. A., Tikkanen, H., Groop, P.-H., & on behalf of the FinnDiane Study Group
- Affiliations
- Folkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland
- Helsinki University Hospital (FI)
- University of Eastern Finland (FI)
- University of Helsinki (FI)
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 2008-02-01
- Volume
- 31
- Issue
- 2
- Pages
- 230-232
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- OpenAlex
- W2143192304
- Cited by
- 108
- References
- 2
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 3 · 2023: 7 · 2022: 5 · 2021: 7 · 2020: 4 · 2019: 11 · 2018: 4 · 2017: 10 · 2016: 8 · 2015: 11 · 2014: 8 · 2013: 4 · 2012: 3
- FWCI
- 3.86
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Diabetes Care (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Wilhelm och Else Stockmanns Stiftelse
- Folkhälsanin Tutkimussäätiö
- Samfundet Folkhälsan
- Waldemar von Frenckells Stiftelse
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Nephrology › Chronic Kidney Disease and Diabetes
- Keywords
- physical activity, type 1 diabetes, diabetes complications, microvascular complications, macrovascular complications, diabetic nephropathy, diabetic retinopathy, cardiovascular disease, leisure-time physical activity, glycemic control, insulin sensitivity, renal function, endothelial function
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Albuminuria, Child, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Diabetic Angiopathies, Diabetic Nephropathies, Finland, Humans, Middle Aged, Surveys and Questionnaires, Exercise, Renal Replacement Therapy
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