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Translating the Diabetes Prevention Program Into an Urban Medically Underserved Community
Open accessAbstract
OBJECTIVE: The objective of this study was to determine if a community-based modified Diabetes Prevention Program Group Lifestyle Balance (GLB) intervention, for individuals with metabolic syndrome, was effective in decreasing risk for type 2 diabetes and cardiovascular disease (CVD) in an urban medically underserved community, and subsequently to determine if improvements in clinical outcomes could be sustained in the short term. RESEARCH DESIGN AND METHODS: This nonrandomized prospective intervention study used a one-group design to test the effectiveness of a community-based GLB intervention. Residents from 11 targeted neighborhoods were screened for metabolic syndrome (n = 573) and took part in a 12-week GLB intervention (n = 88) that addressed safe weight loss and physical activity. RESULTS: A marked decline in weight (46.4% lost > or = 5% and 26.1% lost or = 7%) was observed in individuals after completion of the intervention. Of these subjects, 87.5% (n = 28) and 66.7% (n = 12) sustained the 5% and 7% reduction, respectively, at the 6-month reassessment. Over one-third of the population (43.5%, n = 30) experienced improvements in one or more component of metabolic syndrome, and 73.3% (n = 22) sustained this improvement at the 6-month reassessment. Additional improvements occurred in waist circumference (P < 0.009) and blood pressure levels (P = 0.04) after adjustment for age, sex, race, mean number of GLB classes attended, and time. CONCLUSIONS: Adults in an urban medically underserved community can decrease their risk for type 2 diabetes and CVD through participation in a GLB intervention, and short-term sustainability is feasible. Future research will include long-term follow-up of these subjects.
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“A program targeting a predominantly low-income non-Caucasian urban population delivered a lifestyle intervention in 12 weeks using group sessions and found significant reductions in the proportion of subjects meeting the MetS waist circumference (90% to 68%; p ¼ 0.009) and hypertension (68% to 48%; p ¼ 0.04) criteria over 6 months.At 3 months, 46.4% lost $5% of body weight and 26% lost $7% of body”
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Metadata
- Authors
- Seidel, M. C., Powell, R. O., Zgibor, J. C., Siminerio, L. M., & Piatt, G. A.
- Affiliations
- University of Pittsburgh Medical Center (US)
- University of Pittsburgh (US)
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 2008-04-01
- Volume
- 31
- Issue
- 4
- Pages
- 684-689
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- OpenAlex
- W2102454952
- Cited by
- 164
- References
- 23
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2022: 3 · 2021: 1 · 2020: 3 · 2019: 4 · 2018: 6 · 2017: 5 · 2016: 12 · 2015: 18 · 2014: 20 · 2013: 16 · 2012: 19
- FWCI
- 12.78
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Diabetes Care (publishedVersion)
- PubMed (publishedVersion)
- University Libraries (University of Maryland) (submittedVersion)
- Digital Repository at the University of Maryland (University of Maryland College Park)
- Funders
- Eli Lilly and Company
- Sanofi
- General Mills
- Novo Nordisk
- U.S. Air Force
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Keywords
- Diabetes Prevention Program, metabolic syndrome, type 2 diabetes prevention, cardiovascular risk, community-based intervention, medically underserved populations, urban communities, weight loss, physical activity, waist circumference, blood pressure, intervention sustainability
- MeSH terms
- Adult, Diabetes Mellitus, Diabetes Mellitus, Type 2, Humans, Life Style, Medically Underserved Area, Obesity, Patient Education as Topic, Pennsylvania, Prospective Studies, Unemployment, Urban Population, Risk Assessment, Metabolic Syndrome
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